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Original Article

Human B Cell Differentiation Induced by Microbial Superantigens: Unselected Peripheral Blood Lymphocytes Secrete Polyclonal Immunoglobulin in Response to Mycopusma Arthrztidzs Mitogen

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Pages 23-32 | Received 07 Feb 1992, Accepted 06 Aug 1992, Published online: 07 Jul 2009

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Stuart Macphail. (1999) Superantigens: Mechanisms by which they may Induce, Exacerbate and Control Autoimmune Diseases. International Reviews of Immunology 18:1-2, pages 141-180.
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Articles from other publishers (26)

Goran Abdurrahman, Frieder Schmiedeke, Claus Bachert, Barbara M. Bröker & Silva Holtfreter. (2020) Allergy—A New Role for T Cell Superantigens of Staphylococcus aureus?. Toxins 12:3, pages 176.
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Courtney E Meilleur, Christine M Wardell, Tina S Mele, Jimmy D Dikeakos, Jack R Bennink, Hong-Hua Mu, John K McCormick & S M Mansour Haeryfar. (2019) Bacterial Superantigens Expand and Activate, Rather than Delete or Incapacitate, Preexisting Antigen-Specific Memory CD8+ T Cells. The Journal of Infectious Diseases 219:8, pages 1307-1317.
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Hermínio M. da Rocha Sobrinho, Renata Jarach, Nilzio A. da Silva, Marina T. Shio, Sonia Jancar, Jorge Timenetsky, Milton A. P. Oliveira, Miriam L. Dorta & Fátima Ribeiro-Dias. (2010) Mycoplasmal lipid-associated membrane proteins and Mycoplasma arthritidis mitogen recognition by serum antibodies from patients with rheumatoid arthritis. Rheumatology International 31:7, pages 951-957.
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Wenyi Luo, Huilan Yu, Zuhua Cao, Trenton R. Schoeb, Michele Marron & Kevin Dybvig. (2008) Association of Mycoplasma arthritidis Mitogen with Lethal Toxicity but Not with Arthritis in Mice . Infection and Immunity 76:11, pages 4989-4998.
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Barry C. Cole & Hong-Hua Mu. 2007. Superantigens. Superantigens 37 57 .
Heide Müller-Alouf, Christophe Carnoy, Michel Simonet & Joseph E. Alouf. (2001) Superantigen bacterial toxins: state of the art. Toxicon 39:11, pages 1691-1701.
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William Stohl, Dong Xu, Song Zang, Kyung S. Kim, Lily Li, Julie A. Hanson, Stephen A. Stohlman, Chella S. David & Chaim O. Jacob. (2001) In vivo staphylococcal superantigen-driven polyclonal Ig responses in mice: dependence upon CD4+ cells and human MHC class II. International Immunology 13:10, pages 1291-1300.
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Anke Hendricks, Wolfgang Leibold, Volkhard Kaever & H.-Joachim Schuberth. (2000) Prostaglandin E2 is Variably Induced by Bacterial Superantigens in Bovine Mononuclear Cells and Has a Regulatory Role for the T Cell Proliferative Response. Immunobiology 201:5, pages 493-505.
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Hong-Hua Mu, Allen D. Sawitzke & Barry C. Cole. (2000) Modulation of Cytokine Profiles by the Mycoplasma Superantigen Mycoplasma arthritidis Mitogen Parallels Susceptibility to Arthritis Induced by M. arthritidis . Infection and Immunity 68:3, pages 1142-1149.
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Linda Rasooly & Noel R. Rose. 2000. Nutrition and Immunology. Nutrition and Immunology 355 361 .
Shmuel Razin, David Yogev & Yehudith Naot. (1998) Molecular Biology and Pathogenicity of Mycoplasmas. Microbiology and Molecular Biology Reviews 62:4, pages 1094-1156.
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Leung, Hauk, Strickland, Travers & Norris. (1998) The role of superantigens in human diseases: therapeutic implications for the treatment of skin diseases. British Journal of Dermatology 139, pages 17-29.
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William Stohl, David H. Lynch, Gary C. Starling & Peter A. Kiener. (1998) Superantigen-Driven, CD8+ T Cell-Mediated Down-Regulation: CD95 (Fas)-Dependent Down-Regulation of Human Ig Responses Despite CD95-Independent Killing of Activated B Cells. The Journal of Immunology 161:7, pages 3292-3298.
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William Stohl, Julie E. Elliott, David H. Lynch & Peter A. Kiener. (1998) CD95 (Fas)-Based, Superantigen-Dependent, CD4+ T Cell-Mediated Down-Regulation of Human In Vitro Immunoglobulin Responses. The Journal of Immunology 160:11, pages 5231-5238.
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Andrew S. Hodtsev, Yongwon Choi, Eugenia Spanopoulou & David N. Posnett. (1998) Mycoplasma Superantigen Is a CDR3-dependent Ligand for the T Cell Antigen Receptor. The Journal of Experimental Medicine 187:3, pages 319-327.
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K L KnudtsonM ManoharD E JoynerE A AhmedB C Cole. (1997) Expression of the superantigen Mycoplasma arthritidis mitogen in Escherichia coli and characterization of the recombinant protein. Infection and Immunity 65:12, pages 4965-4971.
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B C Cole, A D Sawitzke, E A Ahmed, C L Atkin & C S David. (1997) Allelic polymorphisms at the H-2A and HLA-DQ loci influence the response of murine lymphocytes to the Mycoplasma arthritidis superantigen MAM. Infection and Immunity 65:10, pages 4190-4198.
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C BernatchezR Al-DaccakP E MayerK MehindateL RinkS MecheriW Mourad. (1997) Functional analysis of Mycoplasma arthritidis-derived mitogen interactions with class II molecules. Infection and Immunity 65:6, pages 2000-2005.
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Raimund W. Kinne, Ernesta Palombo-Kinne & Frank Emmrich. (1997) T-cells in the pathogenesis of rheumatoid arthritis Villains or accomplices?. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1360:2, pages 109-141.
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Monique Lafon & Anne Galelli. (1996) Superantigen related to rabies. Springer Seminars in Immunopathology 17:4, pages 307-318.
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Barry C. Cole & Allen Sawitzke. 1995. Mechanisms and Models in Rheumatoid Arthritis. Mechanisms and Models in Rheumatoid Arthritis 47 66 .
C L AtkinS WeiB C Cole. (1994) The Mycoplasma arthritidis superantigen MAM: purification and identification of an active peptide. Infection and Immunity 62:12, pages 5367-5375.
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K MehindateR al-DaccakL RinkS MecheriJ HébertW Mourad. (1994) Modulation of Mycoplasma arthritidis-derived superantigen-induced cytokine gene expression by dexamethasone and interleukin-4. Infection and Immunity 62:11, pages 4716-4721.
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Gary Zagon, Joseph R. Tumang, Yixin Li, Steven M. Friedman & Mary K. Crow. (2005) Increased frequency of vβ17‐positive t cells in patients with rheumatoid arthritis. Arthritis & Rheumatism 37:10, pages 1431-1440.
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R al-DaccakK MehindateJ HébertL RinkS MecheriW Mourad. (1994) Mycoplasma arthritidis-derived superantigen induces proinflammatory monokine gene expression in the THP-1 human monocytic cell line. Infection and Immunity 62:6, pages 2409-2416.
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N BhardwajA S HodtsevA NisanianS KabakS M FriedmanB C ColeD N Posnett. (1994) Human T-cell responses to Mycoplasma arthritidis-derived superantigen. Infection and Immunity 62:1, pages 135-144.
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