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Original Article

Evidence for an Altered T-Cell Receptor Repertoire in Crohn's Disease

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Pages 301-307 | Received 24 Feb 1994, Published online: 07 Jul 2009

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M. Chiba, S. Hoshina, M. Kono, M. Tobita, T. Fukushima, M. Iizuka, S. Watanabe. (2001) Staphylococcus aureus in Inflammatory Bowel Disease. Scandinavian Journal of Gastroenterology 36:6, pages 615-620.
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Elisa Rosati, Mikhail V Pogorelyy, C Marie Dowds, Frederik T Moller, Signe B Sorensen, Yuri B Lebedev, Norbert Frey, Stefan Schreiber, Martina E Spehlmann, Vibeke Andersen, Ilgar Z Mamedov & Andre Franke. (2020) Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases. Journal of Crohn's and Colitis 14:6, pages 778-790.
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Keerthana Saravanarajan, Atiyekeogbebe Rita Douglas, Mohd Syafiq Ismail, Joseph Omorogbe, Serhiy Semenov, Greg Muphy, Fiona O’Riordan, Deirdre McNamara & Shigeki Nakagome. (2020) Genomic profiling of intestinal T-cell receptor repertoires in inflammatory bowel disease. Genes & Immunity 21:2, pages 109-118.
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Sezin Günaltay, Dirk Repsilber, Gisela Helenius, Nils Nyhlin, Johan Bohr, Olof Hultgren & Elisabeth Hultgren Hörnquist. (2017) Oligoclonal T-cell Receptor Repertoire in Colonic Biopsies of Patients with Microscopic Colitis and Ulcerative Colitis. Inflammatory Bowel Diseases 23:6, pages 932-945.
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Christopher S. J. Probert, Lawrence J. Saubermann, Steven Balk & Richard S. Blumberg. (2007) Repertoire of the αβ T-cell receptor in the intestine. Immunological Reviews 215:1, pages 215-225.
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Joel V. Weinstock. 2004. Infection and Autoimmunity. Infection and Autoimmunity 649 673 .
Joel V. Weinstock. 2003. Granulomatous Infections and Inflammations. Granulomatous Infections and Inflammations 293 320 .
Wolfgang HoltmeierAndreas HennemannEkkehard May, Rainer Duchmann & Wolfgang F. Caspary. (2002) T cell receptor δ repertoire in inflamed and noninflamed colon of patients with IBD analyzed by CDR3 spectratyping. American Journal of Physiology-Gastrointestinal and Liver Physiology 282:6, pages G1024-G1034.
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L. Caradonna, L. Amati, T. Magrone, N.M. Pellegrino, E. JirilloD. Caccavo. (2016) Invited review: Enteric bacteria, lipopolysaccharides and related cytokines in inflammatory bowel disease: biological and clinical significance. Journal of Endotoxin Research 6:3, pages 205-214.
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E. Gemmell, D. A. Grieco, M. P. Cullinan, B. Westerman & G. J. Seymour. (1998) Antigen-specific T-cell receptor Vβ expression in Porphyromonas gingivalis -specific T-cell lines . Oral Microbiology and Immunology 13:6, pages 355-361.
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Ian M Orme & Alan D Roberts. (1998) Changes in integrin/adhesion molecule expression, but not in the T-cell receptor repertoire, in old mice infected with tuberculosis1This work was supported by NIH grant AG-06946.1. Mechanisms of Ageing and Development 105:1-2, pages 19-29.
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L. MAYER. (2010) Review article: Local and systemic regulation of mucosal immunity. Alimentary Pharmacology & Therapeutics 11, pages 81-88.
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E. Gemmell, D.A. Grieco, K. Yamazaki, T. Nakajima & G.J. Seymour. (1997) Expression of receptor β-chain variable region by T cells in human periodontal disease. Archives of Oral Biology 42:10-11, pages 683-694.
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Ulrika Brommé, Johan Grunewald, Annika Scheynius, Olle Olerup & Rolf Hultcrantz. (1997) Preferential Vβ3 usage by hepatic T lymphocytes in patients with primary sclerosing cholangitis. Journal of Hepatology 26:3, pages 527-534.
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Lisa Lih-Brody, Saul R. Powell, Kevin P. Collier, Gautam M. Reddy, Renee Cerchia, Ellen Kahn, Gary S. Weissman, Seymour Katz, Robert A. Floyd, Matthew J. McKinley, Stanley E. Fisher & Gerard E. Mullin. (1996) Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease. Digestive Diseases and Sciences 41:10, pages 2078-2086.
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Gerard E. Mullin, Zev R. Maycon, Lorenz Braun-Elwert, Reneé Cerchia, Stephen P. James, Seymour Katz, Gary S. Weissman, Matthew J. McKinley & Stanley E. Fisher. (1996) Inflammatory Bowel Disease Mucosal Biopsies Have Specialized Lymphokine mRNA Profiles. Inflammatory Bowel Diseases 2:1, pages 16-26.
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Beena Gulwani-Akolkar, Pradip N. Akolkar, Matthew Mckinley, Stanley E. Fisher & Jack Silver. (1995) Crohn's disease is accompanied by changes in the CD4+, but not CD8+, T cell receptor BV repertoire of lamina propria lymphocytes. Clinical Immunology and Immunopathology 77:1, pages 95-106.
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