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Autoimmunity Volume 19, 1994 - Issue 4
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Original Article

Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II

Jochen Seissler Department of Internal Medicine III, University of Leipzig, D-04103, Leipzig
,
Sabine Bieg Department of Internal Medicine III, University of Leipzig, D-04103, Leipzig
,
Nadja Yassin Department of Internal Medicine III, University of Leipzig, D-04103, Leipzig
,
Ludwig Mauch Department Molecular Biology, ELIAS, D-79114, Freiburg
,
Wolfgang Northemann Department Molecular Biology, ELIAS, D-79114, Freiburg
,
Bernhard O. Boehm Department Internal Medicine I, University of Ulm, D-89081, Ulm, Germany
&
Werner A. Scherbaum Department of Internal Medicine III, University of Leipzig, D-04103, Leipzig
 show all
Pages 231-238 | Received 01 Sep 1994, Accepted 29 Nov 1994, Published online: 07 Jul 2009

Citations (20)

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Mohd Wajid A. Khan, Subuhi Sherwani, Wahid A. Khan, Moinuddin & Rashid Ali. (2009) Characterization of hydroxyl radical modified GAD65: A potential autoantigen in type 1 diabetes. Autoimmunity 42:2, pages 150-158.
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Nils G. Morgenthaler, Jochen Seissler, Peter Achenbach, Daniela Glawe, Mark Payton, Hans-Michael Meinck, Michael R. Christie & Werner A. Scherbaum. (1997) Antibodies to the Tyrosine Phosphatase-like Protein IA-2 are highly associated with IDDM, but not with Autoimmune Endocrine Diseases or Stiff Man Syndrome. Autoimmunity 25:4, pages 203-211.
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Articles from other publishers (18)

Tamang Sapana, Wei Li, Fengyan Tian, Wenhao Yan, Binghua Dou, Shuang Hua & Zhihong Zhuo. (2023) A case report of anti-GAD65 antibody-positive autoimmune encephalitis in children associated with autoimmune polyendocrine syndrome type-II and literature review. Frontiers in Immunology 14.
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Salman Mansoor & Kevin Murphy. (2020) Anti-GAD-associated limbic encephalitis: an unusual clinical manifestation from northwest of Ireland. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 56:1.
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Susanne Fauser, Ingo Uttner, Helena Ariño, Werner A. Scherbaum, Albert Saiz & Jan Lewerenz. (2015) Long latency between GAD-antibody detection and development of limbic encephalitis – a case report. BMC Neurology 15:1.
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Zsuzsanna Kemény, Patrícia Pálfi, Judit Demeter, Gyula Poór, Emese Kiss & Péter Bálint. (2013) The stiff-person syndrome: a brief review and report of two cases. Orvosi Hetilap 154:50, pages 1984-1990.
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Mario Manto & P Jissendi. (2010) Brain Imaging in Cerebellar Ataxia Associated with Autoimmune Polyglandular Syndrome Type 2. Journal of Neuroimaging 22:3, pages 308-311.
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Bindu Jayakrishnan, David E. Hoke, Christopher G. Langendorf, Ashley M. Buckle & Merrill J. Rowley. (2011) An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes. PLoS ONE 6:4, pages e18411.
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Claudia Scotti, Paola Mignosi, Paola Filipazzi, Maria Claudia Lazzè, Monica Savio, Donata Cappelletti, Maria Valentina Pasquetto, Enrico Solcia, Vanio Vannini & Patrizia Sommi. (2010) Molecular Alterations in Fibroblasts Exposed to Helicobacter pylori Broth Culture Filtrate: A Potential Trigger of Autoimmunity? . Helicobacter 15:1, pages 76-77.
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Gustavo Mazzi, Dina De Roia, Barbara Cruciatti, Sabrina Matà & Raffaele Catapano. (2008) Plasma exchange for anti GAD associated non paraneoplastic limbic encephalitis. Transfusion and Apheresis Science 39:3, pages 229-233.
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William H. Hoffman, Sandra W. Helman, Elizabeth Sekul, James E. Carroll & Roger A. Vega. (2003) Lambert–Eaton Myasthenic syndrome in a child with an autoimmune phenotype. American Journal of Medical Genetics Part A 119A:1, pages 77-80.
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Hans-Michael Meinck & Philip D. Thompson. (2002) Stiff man syndrome and related conditions. Movement Disorders 17:5, pages 853-866.
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M COSTA, A SAIZ, R CASAMITJANA, M CASTAÑER FERNÁNDEZ, A SANMARTÍ, F GRAUS & D JARAQUEMADA. (2002) T-cell reactivity to glutamic acid decarboxylase in stiff-man syndrome and cerebellar ataxia associated with polyendocrine autoimmunity. Clinical and Experimental Immunology 129:3, pages 471-478.
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Hans-Michael Meinck. (2001) Stiff Man Syndrome. CNS Drugs 15:7, pages 515-526.
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Steven D. Chessler & Åke Lernmark. (2000) Alternative Splicing of GAD67 Results in the Synthesis of a Third Form of Glutamic-acid Decarboxylase in Human Islets and Other Non-neural Tissues. Journal of Biological Chemistry 275:7, pages 5188-5192.
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Powers, Bavik, Tremble, Daw, Scherbaum & Banga. (1999) Comparative analysis of epitope recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different autoimmune disorders. Clinical and Experimental Immunology 118:3, pages 349-356.
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Jadwiga Furmaniak, Jane Sanders & Bernard Rees Smith. 1999. Autoimmune Endocrinopathies. Autoimmune Endocrinopathies 183 216 .
Petra Obermayer-Straub & Michael P. Manns. (1998) 6 Autoimmune polyglandular syndromes. Baillière's Clinical Gastroenterology 12:2, pages 293-315.
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P. Peterson, R. Uibo & K. J. E. Krohn. 1998. Endocrine Autoimmunity and Associated Conditions. Endocrine Autoimmunity and Associated Conditions 163 182 .
Michael Powell, Louise Prentice, Takayuki Asawa, Ryoji Kato, Joanna Sawicka, Hideaki Tanaka, Vaughan Petersen, Andrea Munkley, Sharon Morgan, Bernard Rees Smith & Jadwiga Furmaniak. (1996) Glutamic acid decarboxylase autoantibody assay using 125I-labelled recombinant GAD65 produced in yeast. Clinica Chimica Acta 256:2, pages 175-188.
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