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Autoimmunity Volume 24, 1996 - Issue 1
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Original Article

Influence of the Light Chain Repertoire on Immunoglobulin Genes Encoding Thyroid Autoantibody Fab from Combinatorial Libraries

Juan Carlos Jaume Thyroid Molecular Biology Unit, Veterans' Administration Medical Center and the University of California, San Francisco, California
,
Stefano Portolano Thyroid Molecular Biology Unit, Veterans' Administration Medical Center and the University of California, San Francisco, California
,
Basil Rapoport Thyroid Molecular Biology Unit, Veterans' Administration Medical Center and the University of California, San Francisco, California
&
Sandra M. Mclachlan Thyroid Molecular Biology Unit, Veterans' Administration Medical Center and the University of California, San Francisco, California
Pages 11-23 | Received 01 Mar 1996, Accepted 23 Apr 1996, Published online: 07 Jul 2009

Citations (10)

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Read on this site (2)

Sandra M. McLachlan & Basil Rapoport. (2000) Autoimmune Response to the Thyroid in Humans: Thyroid Peroxidase-The Common Autoantigenic Denominator. International Reviews of Immunology 19:6, pages 587-618.
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Ayumu Kakinuma, Stefano Portolano, Gregorio Chazenbalk, Basil Rapoport & Sandra M. McLachlan. (1997) Insight into Screening Immunoglobulin Gene Combinatorial Libraries in a Phage Display Vector: A Tale of Two Antibodies. Autoimmunity 25:2, pages 73-84.
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Articles from other publishers (8)

Sandra M. McLachlanBasil Rapoport. (2007) Thyroid Peroxidase as an Autoantigen. Thyroid 17:10, pages 939-948.
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Jing Wang & Xuejun Zhu. (2004) The role of pathogenic B-cell clones in antibody mediated autoimmune disorders. Journal of Dermatological Science 36:3, pages 141-148.
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Francesco Latrofa, Pavel Pichurin, Jin Guo, Basil Rapoport & Sandra M. McLachlan. (2003) Thyroglobulin-Thyroperoxidase Autoantibodies Are Polyreactive, Not Bispecific: Analysis Using Human Monoclonal Autoantibodies. The Journal of Clinical Endocrinology & Metabolism 88:1, pages 371-378.
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J GUO, Y WANG, J C JAUME, B RAPOPORT & S M MCLACHLAN. (1999) Rarity of autoantibodies to a major autoantigen, thyroid peroxidase, that interact with denatured antigen or with epitopes outside the immunodominant region. Clinical and Experimental Immunology 117:1, pages 19-29.
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Pavel Pichurin, Jin Guo, Xinmin Yan, Basil Rapoport & Sandra M. McLachlan. (2001) Human Monoclonal Autoantibodies to B-Cell Epitopes Outside the Thyroid Peroxidase Autoantibody Immunodominant Region. Thyroid 11:4, pages 301-313.
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Nicolas Chapal, Sylvie Peraldi-Roux, Damien Bresson, Martine Pugniere, Jean-Claude Mani, Claude Granier, Line Baldet, Bernard Guerrier, Bernard Pau & Majida Bouanani. (2000) Human Anti-Thyroid Peroxidase Single-Chain Fragment Variable of Ig Isolated from a Combinatorial Library Assembled In-Cell: Insights into the In Vivo Situation. The Journal of Immunology 164:8, pages 4162-4169.
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Richard Mclntosh, Philip Watson & Anthony Weetman. (1998) Somatic hypermutation in antoimmune thyroid disease. Immunological Reviews 162:1, pages 219-231.
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Juan Carlos Jaume, Jin Guo, Ayumu Kakinuma, Basil Rapoport & Sandra M. McLachlan. (1997) The Epitopic “Fingerprint” of Thyroid Peroxidase-Specific Fab Isolated from a Patient's Thyroid Gland by the Combinatorial Library Approach Resembles That of Autoantibodies in the Donor's Serum. Clinical Immunology and Immunopathology 84:2, pages 150-157.
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