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Original Article

Beta-Cell Rest: A Strategy for the Prevention of Autoimmune Diabetes

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Pages 117-122 | Received 09 Dec 1996, Accepted 07 Feb 1997, Published online: 07 Jul 2009

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F Anders Karlsson, Christian Berne, Elisabeth Björk, Mikael Kullin, Zhanchun Li, Jing-Yie Ma, Anna Schölin & Lijun Zhao. (2000) Beta-cell Activity and Destruction in Type 1 Diabetes. Upsala Journal of Medical Sciences 105:2, pages 85-95.
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Articles from other publishers (17)

Mary Froehlich, Naoru Koizumi, Rosy M. James, Ana Gayle Weatherly Christian, Ankur Choubey, Sunil Patel, Jorge Ortiz & Eric J. Siskind. (2022) The Use of Vasopressors During Deceased Donor Pancreas Procurement Decreases the Risk of Pancreas Transplant Graft Failure. Pancreas 51:7, pages 747-751.
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Teresa Vanessa Fiorentino, Francesca Casiraghi, Alberto M. Davalli, Giovanna Finzi, Stefano La Rosa, Paul B. Higgins, Gregory A. Abrahamian, Alessandro Marando, Fausto Sessa, Carla Perego, Rodolfo Guardado-Mendoza, Subhash Kamath, Andrea Ricotti, Paolo Fiorina, Giuseppe Daniele, Ana M. Paez, Francesco Andreozzi, Raul A. Bastarracea, Anthony G. Comuzzie, Amalia Gastaldelli, Alberto O. Chavez, Eliana S. Di Cairano, Patrice Frost, Livio Luzi, Edward J. Dick, Glenn A. Halff, Ralph A. DeFronzo & Franco Folli. (2019) Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas. JCI Insight 4:20.
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Leif Jansson, Per-Ola Carlsson, Birgitta Bodin & Örjan Källskog. (2011) Flow distribution during infusion of UW and HTK solution in anaesthetised rats. Langenbeck's Archives of Surgery 396:5, pages 677-683.
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Maria Anita RadtkeIngrid NermoenMagnus KollindSvein SkeieJan Inge SørheimJohan SvartbergIngrid HalsTorolf MoenGry Høst DørflingerValdemar Grill. (2010) Six Months of Diazoxide Treatment at Bedtime in Newly Diagnosed Subjects With Type 1 Diabetes Does Not Influence Parameters of β-Cell Function and Autoimmunity but Improves Glycemic Control. Diabetes Care 33:3, pages 589-594.
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Rebecca J Brown & Kristina I Rother. (2008) Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data. Pediatric Diabetes 9:3pt2, pages 14-22.
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N. C. Schloot, P. Hanifi-Moghaddam, N. Aabenhus-Andersen, B. Z. Alizadeh, M. T. Saha, M. Knip, D. Devendra, T. Wilkin, E. Bonifacio, B. O. Roep & H. Kolb. (2007) Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission. Diabetic Medicine 24:5, pages 512-520.
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Beate Karges, Ivana Durinovic-Belló, Eberhard Heinze, Klaus-Michael Debatin, Bernhard Boehm & Wolfram Karges. (2006) Immunological mechanisms associated with long-term remission of human type 1 diabetes. Diabetes/Metabolism Research and Reviews 22:3, pages 184-189.
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M. O. Larsen, B. Rolin, C. F. Gotfredsen, R. D. Carr & J. J. Holst. (2004) Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide?streptozotocin G�ttingen minipig after oral glucose in vivo and in the perfused pancreas. Diabetologia 47:11, pages 1873-1878.
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Eva Örtqvist, Elisabeth Björk, Måna Wallensteen, Johnny Ludvigsson, Jan Åman, Calle Johansson, Gun Forsander, Fredrik Lindgren, Lars Berglund, Mats Bengtsson, Christian Berne, Bengt Persson & F. Anders Karlsson. (2004) Temporary Preservation of β-Cell Function by Diazoxide Treatment in Childhood Type 1 Diabetes. Diabetes Care 27:9, pages 2191-2197.
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Anna Schölin, Agneta Siegbahn, Lars Lind, Christian Berne, Göran Sundkvist, Elisabeth Björk & F. Anders Karlsson. (2004) CRP and IL‐6 concentrations are associated with poor glycemic control despite preserved β‐cell function during the first year after diagnosis of type 1 diabetes. Diabetes/Metabolism Research and Reviews 20:3, pages 205-210.
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Leif Jansson, Mikael Kullin, F. Anders Karlsson, Birgitta Bodin, John Bondo Hansen & Stellan Sandler. (2003) KATP Channels and Pancreatic Islet Blood Flow in Anesthetized Rats. Diabetes 52:8, pages 2043-2048.
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M. Kullin, Z. Li, J. Bondo Hansen, N. Welsh, F. A. Karlsson & S. Sandler. (2003) Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1β mediated suppression—possible involvement of the mitochondrial membrane potential. Diabetologia 46:1, pages 80-88.
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Masafumi Matsuda, Fumiko Kawasaki, Yoshiki Mikami, Yasuo Takeuchi, Mieko Saito, Masaaki Eto & Kohei Kaku. (2002) Rescue of beta-cell exhaustion by diazoxide after the development of diabetes mellitus in rats with streptozotocin-induced diabetes. European Journal of Pharmacology 453:1, pages 141-148.
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Michael Dabrowski, Frances M. Ashcroft, Rebecca Ashfield, Philippe Lebrun, Bernard Pirotte, Jan Egebjerg, John Bondo Hansen & Philip Wahl. (2002) The Novel Diazoxide Analog 3-Isopropylamino-7-Methoxy- 4H -1,2,4-Benzothiadiazine 1,1-Dioxide Is a Selective Kir6.2/SUR1 Channel Opener . Diabetes 51:6, pages 1896-1906.
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JERRY P. PALMER. (2006) Beta Cell Rest and Recovery-Does It Bring Patients with Latent Autoimmune Diabetes in Adults to Euglycemia?. Annals of the New York Academy of Sciences 958:1, pages 89-98.
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EVA STRANDELL, ANNE KAAS, MARIE-LOUISE HARTOFT-NIELSEN, TROELS BOCK, KARSTEN BUSCHARD & KLAUS BENDTZEN. (1999) Cytokine production in NOD mice on prophylactic insulin therapy. APMIS 107:1-6, pages 413-419.
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A. Schölin, C. Berne, E. Schvarcz, F. A. Karlsson & E. Björk. (2001) Factors predicting clinical remission in adult patients with type 1 diabetes. Journal of Internal Medicine 245:2, pages 155-162.
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