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Original Article

The APC1 Concept of Type I Diabetes

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Pages 179-184 | Received 21 Apr 1997, Accepted 09 Sep 1997, Published online: 07 Jul 2009

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Anne M. Delles, Kate Rittenhouse-Olson, Janet Morgan & Allan R. Oseroff. (2002) A SIMPLE METHOD FOR THE PURIFICATION OF HUMAN PERIPHERAL BLOOD ANTIGEN PRESENTING CELLS (DENDRITIC CELLS, MONOCYTES/MACROPHAGES, AND B LYMPHOCYTES). Immunological Investigations 31:3-4, pages 233-245.
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Wen Li, Yoshimasa Tanaka & Haruki Okamura. 2014. Cytokine Frontiers. Cytokine Frontiers 103 123 .
L Shoda, H Kreuwel, K Gadkar, Y ZhengC Whiting, M Atkinson, J Bluestone, D Mathis, D Young & S Ramanujan. (2010) The Type 1 Diabetes PhysioLab® Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse. Clinical and Experimental Immunology 161:2, pages 250-267.
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Stewart Leung, April Holbrook, Beverly King, Hong-Tao Lu, Vincent Evans, Neil Miyamoto, Cornell Mallari, Susan Harvey, Dave Davey, Elena Ho, Wei-Wei Li, John Parkinson, Richard Horuk, Stefan Jaroch, Markus Berger, Werner Skuballa, Christopher West, Rebecca Pulk, Gary Phillips, Judi Bryant, Babu Subramanyam, Caralee Schaefer, Hugh Salamon, Eric Lyons, Daniela Schilling, Henrik Seidel, Joern Kraetzschmar, Michael Snider & Daniel Perez. (2005) Differential Inhibition of Inducible T Cell Cytokine Secretion by Potent Iron Chelators. SLAS Discovery 10:2, pages 157-167.
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Michael WELSH, Charlotte WELSH, Maria EKMAN, Johan DIXELIUS, Robert HÄGERKVIST, Cecilia ANNERÉN, Björn ÅKERBLOM, Siavosh MAHBOOBI, Subhashini CHANDRASEKHARANEdison T. LIU. (2004) The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity. Biochemical Journal 382:1, pages 261-268.
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N.S. Stoy. (2002) Monocyte/macrophage initiation of organ-specific autoimmunity: the ultimate ‘bystander’ hypothesis?. Medical Hypotheses 58:4, pages 312-326.
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W. Aubrey Soskolne & Avigdor Klinger. (2001) The Relationship Between Periodontal Diseases and Diabetes: An Overview. Annals of Periodontology 6:1, pages 91-98.
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J.B. Classen & D.C. Classen. (2001) Vaccines and the risk of insulin-dependent diabetes (IDDM): potential mechanism of action. Medical Hypotheses 57:5, pages 532-538.
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Laurence KesslerSylviane TritschlerAlain BohbotSeverine SigristVeronique KarstenSophie BoivinPatrick DufourAlain BelcourtMichel Pinget. (2001) Macrophage Activation in Type 1 Diabetic Patients With Catheter Obstruction During Peritoneal Insulin Delivery With an Implantable Pump. Diabetes Care 24:2, pages 302-307.
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Vidya Ganapathy, Tatyana Gurlo, Hilde O. Jarstadmarken & Hermann von Grafenstein. (2000) Regulation of TCR-induced IFN-γ release from islet-reactive non-obese diabetic CD8+ T cells by prostaglandin E2 receptor signaling. International Immunology 12:6, pages 851-860.
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Nicoletti, Di Marco, Zaccone, Magro, Di Mauro, Grasso & Meroni. (2001) Endogenous interleukin‐12 only plays a key pathogenetic role in non‐obese diabetic mouse diabetes during the very early stages of the disease. Immunology 97:3, pages 367-370.
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Wassim Y. Almawi, Hala Tamim & Sami T. Azar. (1999) T Helper Type 1 and 2 Cytokines Mediate the Onset and Progression of Type I (Insulin-Dependent) Diabetes. The Journal of Clinical Endocrinology & Metabolism 84:5, pages 1497-1502.
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Petr Murzenok & Vitaly Goranov. (1999) Do local immune-neuroendocrine disturbances initiate diabetes?. Canadian Journal of Physiology and Pharmacology 77:3, pages 147-155.
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