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Original Article

Lack of Association between CTLA-4 Gene Polymorphism and IDDM in Japanese Subjects

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Pages 53-56 | Received 16 Feb 1998, Published online: 07 Jul 2009

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Yoshiyuki Ban, Matsuo Taniyama, Teruaki Tozaki, Tatsuo Yanagawa, Satoru Yamada, Taro Maruyama, Akira Kasuga, Motowo Tomita & Yoshio Ban. (2001) No Association of Type 1 Diabetes with a Microsatellite Marker for CTLA-4 in a Japanese Population. Autoimmunity 34:1, pages 39-43.
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Articles from other publishers (24)

Hai Duc Nguyen, Amir Ardeshir, Vivian A. Fonseca & Woong-Ki Kim. (2024) Cluster of differentiation molecules in the metabolic syndrome. Clinica Chimica Acta 561, pages 119819.
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Ahmed Al-Hakami. (2020) Serum sCTLA-4 level is not associated with type 1 diabetes or the coexistence of autoantibodies in children and adolescent patients from the southern region of Saudi Arabia. Autoimmunity Highlights 11:1.
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Bo Wang, Wei Du, Yutao Jia, Xiaobai Zhang & Guorui Ma. (2017) Cytotoxic T-lymphocyte-associated protein 4 +49A/G polymorphisms contribute to the risk of type 1 diabetes in children: An updated systematic review and meta-analysis with trial sequential analysis. Oncotarget 8:6, pages 10553-10564.
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Alessandro P. Delitala, Giuseppe Fanciulli, Magdalena Zoledziewska, Maristella Pitzalis, Pierpaolo Pusceddu, Paola Frongia, Loreta Puddu, Alessandra Errigo, Margherita Maioli, Giuseppe Delitala & Giovanni M. Pes. (2014) Allelic variant in CTLA4 is associated with thyroid failure and faster β ‐cell exhaustion in latent autoimmune diabetes in adults CTLA4 等位基因变异与成人迟发型自身免疫性糖尿病患者的甲状腺功能衰竭以及 β ‐细胞加速衰竭有关 . Journal of Diabetes 7:1, pages 68-73.
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Joanne YW Ng, Fiona OJ Luk, Timothy YY Lai & Chi-Pui Pang. (2014) Influence of molecular genetics in Vogt-Koyanagi-Harada disease. Journal of Ophthalmic Inflammation and Infection 4:1.
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Ahmed A. El-Kafoury, Medhat Haroun, Amira Mohamed Embaby & Ali Salem Dawoods. (2014) The association of polymorphic sites in some genes with type 1 diabetes mellitus in a sample of Egyptian children. Egyptian Journal of Medical Human Genetics 15:3, pages 265-272.
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Jingnan Wang, Lianyong Liu, Junhua Ma, Fei Sun, Zefei Zhao & Mingjun Gu. (2014) Common Variants on Cytotoxic T Lymphocyte Antigen-4 Polymorphisms Contributes to Type 1 Diabetes Susceptibility: Evidence Based on 58 Studies. PLoS ONE 9:1, pages e85982.
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Zixian Chen, Min Fei, Da Fu, Liang Zhang, Yushui Ma, Yichao Wang, Feng Zhang, Qing Xia & Xiaofeng Wang. (2013) Association between cytotoxic T lymphocyte antigen-4 polymorphism and type 1 diabetes: A meta-analysis. Gene 516:2, pages 263-270.
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Xiaoyu SiXiufeng ZhangYing LuoWenru Tang. (2012) Association Between the CTLA-4 +49A/G Polymorphism and Type 1 Diabetes: A Meta-Analysis. Genetic Testing and Molecular Biomarkers 16:11, pages 1336-1342.
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Song-tao Tang, Hai-qin Tang, Qiu Zhang, Chang-jiang Wang, You-min Wang & Wen-jia Peng. (2012) Association of cytotoxic T-lymphocyte associated antigen 4 gene polymorphism with type 1 diabetes mellitus: A meta-analysis. Gene 508:2, pages 165-187.
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Min Ho JungJeesuk YuChoong Ho ShinByung Kyu SuhSei Won YangByung Churl Lee. (2009) Association of Cytotoxic T Lymphocyte Antigen-4 Gene Polymorphisms and HLA Class II Alleles with the Development of Type 1 Diabetes in Korean Children and Adolescents. Journal of Korean Medical Science 24:6, pages 1004.
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Liping Du, Peizeng Yang, Shengping Hou, Xiaomin Lin, Hongyan Zhou, Xiangkun Huang, Li Wang & Aize Kijlstra. (2008) Association of the CTLA-4 gene with Vogt–Koyanagi–Harada syndrome. Clinical Immunology 127:1, pages 43-48.
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K. Haller, K. Kisand, H. Pisarev, L. Salur, T. Laisk, V. Nemvalts & R. Uibo. (2007) Insulin gene VNTR, CTLA‐4 +49A/G and HLA‐DQB1 alleles distinguish latent autoimmune diabetes in adults from type 1 diabetes and from type 2 diabetes group . Tissue Antigens 69:2, pages 121-127.
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Brian Golden, Lara Levin, Yoshiyuki Ban, Erlinda Concepcion, David A. Greenberg & Yaron Tomer. (2005) Genetic Analysis of Families with Autoimmune Diabetes and Thyroiditis: Evidence for Common and Unique Genes. The Journal of Clinical Endocrinology & Metabolism 90:8, pages 4904-4911.
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Fotini K. Kavvoura & John P. A. Ioannidis. (2005) CTLA-4 Gene Polymorphisms and Susceptibility to Type 1 Diabetes Mellitus: A HuGE Review and Meta-Analysis. American Journal of Epidemiology 162:1, pages 3-16.
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K. Haller, K. Kisand, V. Nemvalts, A.‐P. Laine, J. Ilonen & R. Uibo. (2004) Type 1 diabetes is insulin −2221 MspI and CTLA‐4 +49 A/G polymorphism dependent. European Journal of Clinical Investigation 34:8, pages 543-548.
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Pierre A. Zalloua, Antoine Abchee, Hadia Shbaklo, Tony G. Zreik, Henry Terwedow, Georges Halaby & Sami T. Azar. (2004) Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene. Human Immunology 65:7, pages 719-724.
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Ainhoa Martín-Pagola, Guiomar Pérez de Nanclares, Juan C. Vitoria, J. Ramón Bilbao, Lourdes Ortiz, Paul Zubillaga & Luis Castaño. (2003) No Association of CTLA4 Gene With Celiac Disease in the Basque Population. Journal of Pediatric Gastroenterology and Nutrition 37:2, pages 142-145.
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Ainhoa Martín‐Pagola, Guiomar Pérez de Nanclares, Juan C. Vitoria, J. Ramón Bilbao, Lourdes Ortiz, Paul Zubillaga & Luis Castaño. (2003) No Association of CTLA4 Gene With Celiac Disease in the Basque Population . Journal of Pediatric Gastroenterology and Nutrition 37:2, pages 142-145.
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Mie Mochizuki, Shin Amemiya, Kisho Kobayashi, Koji Kobayashi, Yoshie Shimura, Toshihide Ishihara, Yoshiko Nakagomi, Kazumichi Onigata, Shinya Tamai, Akira Kasuga & Shinpei Nanazawa. (2003) Association of the CTLA-4 Gene 49 A/G Polymorphism With Type 1 Diabetes and Autoimmune Thyroid Disease in Japanese Children. Diabetes Care 26:3, pages 843-847.
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E. Yung, P. S. Cheng, T. F. Fok & G. W. K. Wong. (2002) CTLA‐4 gene A–G polymorphism and childhood Graves’ disease. Clinical Endocrinology 56:5, pages 649-653.
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Noriko Kikuoka, Shigetaka Sugihara, Tatsuo Yanagawa, Ayako Ikezaki, Hye Sook Kim, Hisafumi Matsuoka, Yasuyuki Kobayashi, Kunio Wataki, Susumu Konda, Hirokazu Sato, Shigeki Miyamoto, Nozomu Sasaki, Tateo Sakamaki, Hiroo Niimi & Mitsunori Murata. (2008) Cytotoxic T lymphocyte antigen 4 gene polymorphism confers susceptibility to Type 1 diabetes in Japanese children: analysis of association with HLA genotypes and autoantibodies. Clinical Endocrinology 55:5, pages 597-603.
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Satoru Yamada, Yoshiko Motohashi, Tatsuo Yanagawa, Taro Maruyama, Akira Kasuga, Hiroshi Hirose, Koichi Matsubara, Akira Shimada & Takao Saruta. (2001) NeuroD/BETA2 Gene G→A Polymorphism May Affect Onset Pattern of Type 1 Diabetes in Japanese. Diabetes Care 24:8, pages 1438-1441.
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Alberto Pugliese. 2001. Genetics of Diabetes Mellitus. Genetics of Diabetes Mellitus 25 42 .

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