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Immunopharmacology and Immunotoxicology Volume 35, 2013 - Issue 4

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Research Article

[6]-Shogaol inhibits the production of proinflammatory cytokines via regulation of NF-κB and phosphorylation of JNK in HMC-1 cells

Youngjoo SohnCollege of Korean Medicine, Kyung Hee University, 1, Hoegi-dong, Dongdaemun-gu Seoul, 130-701Republic of Korea

Na-Young HanCollege of Korean Medicine, Kyung Hee University, 1, Hoegi-dong, Dongdaemun-gu Seoul, 130-701Republic of Korea

Min Jung LeeCollege of Korean Medicine, Kyung Hee University, 1, Hoegi-dong, Dongdaemun-gu Seoul, 130-701Republic of Korea

Hyun-Joo ChoCollege of Korean Medicine, Kyung Hee University, 1, Hoegi-dong, Dongdaemun-gu Seoul, 130-701Republic of Korea

Hyuk-Sang JungCollege of Korean Medicine, Kyung Hee University, 1, Hoegi-dong, Dongdaemun-gu Seoul, 130-701Republic of KoreaCorrespondence[email protected]

Pages 462-470 | Received 26 Nov 2012, Accepted 01 Mar 2013, Published online: 16 Apr 2013

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https://doi.org/10.3109/08923973.2013.782318

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Ha-Rim Kim, Eun-Mi Noh & Seon-Young Kim. (2023) Anti-inflammatory effect and signaling mechanism of 8-shogaol and 10-shogaol in a dextran sodium sulfate-induced colitis mouse model. Heliyon 9:1, pages e12778.
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Iris Bischoff-Kont, Tobias Primke, Lea S. Niebergall, Thomas Zech & Robert Fürst. (2022) Ginger Constituent 6-Shogaol Inhibits Inflammation- and Angiogenesis-Related Cell Functions in Primary Human Endothelial Cells. Frontiers in Pharmacology 13.
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Xiaoxuan Guo, Jing Qiu & Yongzhong Qian. (2021) 6-Shogaol Mitigates Sepsis-Associated Hepatic Injury through Transcriptional Regulation. Nutrients 13:10, pages 3427.
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Iris Bischoff-Kont & Robert Fürst. (2021) Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes. Pharmaceuticals 14:6, pages 571.
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Yong‐Gun Kim, Myoung Ok Kim, Sung‐Hyun Kim, Hyo Jeong Kim, Nitin Kumar Pokhrel, Ji Hye Lee, Heon‐Jin Lee, Jae‐Young Kim & Youngkyun Lee. (2019) 6‐Shogaol, an active ingredient of ginger, inhibits osteoclastogenesis and alveolar bone resorption in ligature‐induced periodontitis in mice. Journal of Periodontology 91:6, pages 809-818.
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Yun‑Mi Kang, Kyung‑Sook Chung, In‑Hoon Kook, Yoon‑Bum Kook, Hyunsu Bae, Minho Lee & Hyo‑Jin An. (2018) Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses. International Journal of Molecular Medicine.
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Guang Zheng, Nannan Wang & Hongtao Guo. (2017) Digestive functions regulated by 6-shogaol towards stomach and small intestine. Digestive functions regulated by 6-shogaol towards stomach and small intestine.

Julia Luettig, Rita Rosenthal, In-Fah M. Lee, Susanne M. Krug & Jörg D. Schulzke. (2016) The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling. Molecular Nutrition & Food Research 60:12, pages 2576-2586.
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Minho Moon, Hyo Geun Kim, Jin Gyu Choi, Hyein Oh, Paula KJ Lee, Sang Keun Ha, Sun Yeou Kim, Yongkon Park, Youngbuhm Huh & Myung Sook Oh. (2014) 6-Shogaol, an active constituent of ginger, attenuates neuroinflammation and cognitive deficits in animal models of dementia. Biochemical and Biophysical Research Communications 449:1, pages 8-13.
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[6]-Shogaol inhibits the production of proinflammatory cytokines via regulation of NF-κB and phosphorylation of JNK in HMC-1 cells

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[6]-Shogaol inhibits the production of proinflammatory cytokines via regulation of NF-κB and phosphorylation of JNK in HMC-1 cells

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