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Immunopharmacology and Immunotoxicology Volume 36, 2014 - Issue 2
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Research Article

In vitro immunomodulatory effects of 5-amino-3-methyl-4-isoxazolecarboxylic acid hydrazide on the cellular immune response

Angelika DryndaDepartment of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life SciencesCorrespondence[email protected]
,
Marcin MączyńskiDepartment of Organic Chemistry, Faculty of Pharmacy, Wrocław Medical University WrocławPoland
,
Stanisław RyngDepartment of Organic Chemistry, Faculty of Pharmacy, Wrocław Medical University WrocławPoland
&
Bożena Obmińska-MrukowiczDepartment of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences
Pages 150-157 | Received 02 Oct 2013, Accepted 29 Jan 2014, Published online: 04 Mar 2014

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Paulina Płoszaj, Andrzej Regiec, Stanisław Ryng, Agnieszka Piwowar & Marian L. Kruzel. (2016) Influence of 5-amino-3-methyl-4-isoxazolecarbohydrazide on selective gene expression in Caco-2 cultured cells. Immunopharmacology and Immunotoxicology 38:6, pages 486-494.
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Angelika Drynda, Bożena Obmińska-Mrukowicz, Marcin Mączyński & Stanisław Ryng. (2015) The effect of 5-amino-3-methyl-4-isoxazolecarboxylic acid hydrazide on lymphocyte subsets and humoral immune response in SRBC-immunized mice. Immunopharmacology and Immunotoxicology 37:2, pages 148-157.
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Articles from other publishers (10)

Izabela Jęśkowiak-Kossakowska, Paulina Jawień, Edward Krzyżak, Marcin Mączyński, Roman Szafran, Adam Szeląg, Maciej Janeczek & Benita Wiatrak. (2023) Search for immunomodulatory compounds with antiproliferative activity against melanoma. Biomedicine & Pharmacotherapy 160, pages 114374.
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Urszula Bąchor, Adam Junka, Malwina Brożyna & Marcin Mączyński. (2023) The In Vitro Impact of Isoxazole Derivatives on Pathogenic Biofilm and Cytotoxicity of Fibroblast Cell Line. International Journal of Molecular Sciences 24:3, pages 2997.
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Jian Yang, Ya-rong Lin, Bo-jun Xiong, Ze-hong Chen, Yu-fei Luo, Ying Xu, Yan-ping Su, Hui-hui Huang & Chang-xi Yu. (2022) Regulation effect of koumine on T-helper cell polarization in rheumatoid arthritis. European Journal of Pharmacology 937, pages 175387.
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Aleksandra Sochacka-Ćwikła, Marcin Mączyński, Żaneta Czyżnikowska, Benita Wiatrak, Izabela Jęśkowiak, Albert Czerski & Andrzej Regiec. (2022) New Oxazolo[5,4-d]pyrimidines as Potential Anticancer Agents: Their Design, Synthesis, and In Vitro Biological Activity Research. International Journal of Molecular Sciences 23:19, pages 11694.
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Aleksandra Sochacka-Ćwikła, Andrzej Regiec, Michał Zimecki, Jolanta Artym, Ewa Zaczyńska, Maja Kocięba, Iwona Kochanowska, Iwona Bryndal, Anna Pyra & Marcin Mączyński. (2020) Synthesis and Biological Activity of New 7-Amino-oxazolo[5,4-d]Pyrimidine Derivatives. Molecules 25:15, pages 3558.
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Michał Zimecki, Urszula Bąchor & Marcin Mączyński. (2018) Isoxazole Derivatives as Regulators of Immune Functions. Molecules 23:10, pages 2724.
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Andrzej Regiec, Piotr Wojciechowski, Adam Pietraszko & Marcin Mączyński. (2018) Infrared spectra and other properties predictions of 5-amino-3-methyl-4-isoxazolecarbohydrazide with electric field simulation using CPC model. Journal of Molecular Structure 1161, pages 320-338.
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Angelika Sysak & Bożena Obmińska-Mrukowicz. (2017) Isoxazole ring as a useful scaffold in a search for new therapeutic agents. European Journal of Medicinal Chemistry 137, pages 292-309.
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Angelika Drynda, Bożena Obmińska-Mrukowicz, Ewa Zaczyńska, Michał Zimecki, Iwona Kochanowska, Stanisław Ryng & Marcin Mączyński. (2017) 5-Amino-3-methyl-4-isoxazolecarboxylic acid hydrazide derivatives with in vitro immunomodulatory activities. Chemical Biology & Drug Design 89:5, pages 705-713.
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Angelika Drynda, Bożena Obmińska-Mrukowicz, Ewa Zaczyńska, Michał Zimecki, Stanisław Ryng & Marcin Mączyński. (2016) Immunoregulatory effects of 4-(4-chlorophenyl)-1-(5-amino-3-methylisoxazole-4-carbonyl)-thiosemicarbazide (06K) in non-immunized and SRBC-immunized mice. Journal of Pharmacy and Pharmacology 68:12, pages 1613-1620.
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