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Research Article

Oral Administration of Chlorella Vulgaris Augments Concomitant Antitumor Immunity

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Pages 277-291 | Published online: 28 Sep 2008

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Read on this site (6)

Takayuki Komatsu, Nobuo Kido, Tsuyoshi Sugiyama & Takashi Yokochi. (2013) Antiviral activity of acidic polysaccharides from Coccomyxa gloeobotrydiformi, a green alga, against an in vitro human influenza A virus infection. Immunopharmacology and Immunotoxicology 35:1, pages 1-7.
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Hyo-Jin An, Hong-Kun Rim, Hyun-Ja Jeong, Seung-Heon Hong, Jae-Young Um & Hyung-Min Kim. (2010) Hot water extracts of Chlorella vulgaris improve immune function in protein-deficient weanling mice and immune cells. Immunopharmacology and Immunotoxicology 32:4, pages 585-592.
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Aline Lisie Ramos, Cristiane Okuda Torello & MaryL. S. Queiroz. (2010) Chlorella vulgaris Modulates Immunomyelopoietic Activity and Enhances the Resistance of Tumor-Bearing Mice. Nutrition and Cancer 62:8, pages 1170-1180.
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Mary L.S. Queiroz, Claudia Bincoletto, Marize C. Valadares, Denise C. M. Dantas & Leonilda M. B. Santos. (2002) EFFECTS OF CHLORELLA VULGARIS EXTRACT ON CYTOKINES PRODUCTION IN LISTERIA MONOCYTOGENES INFECTED MICE. Immunopharmacology and Immunotoxicology 24:3, pages 483-496.
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Giselle Z. Justo, Márcia R. Silva & Mary L. S. Queiroz. (2001) EFFECTS OF THE GREEN ALGAE CHLORELLA VULGARIS ON THE RESPONSE OF THE HOST HEMATOPOIETIC SYSTEM TO INTRAPERITONEAL EHRLICH ASCITES TUMOR TRANSPLANTATION IN MICE. Immunopharmacology and Immunotoxicology 23:1, pages 119-132.
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Denise C. M. Dantas, Ramon Kaneno & Mary L. S. Queiroz. (1999) The Effects of Chlorella Vulgaris in The Protection of Mice Infected With Listeria Monocytogenes. Role of Natural Killer Cells. Immunopharmacology and Immunotoxicology 21:3, pages 609-619.
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Eleni Papakonstantinou, Konstantina Dragoumani, Flora Bacopoulou, George P. Chrousos, Elias Eliopoulos & Dimitrios Vlachakis. 2023. GeNeDis 2022. GeNeDis 2022 245 250 .
Susumu Ishiguro, Mary Roth, Ruth Welti, Mayme Loyd, Ravindra Thakkar, Morgan Phillips, Nicole Robben, Deepa Upreti, Ayaka Nakashima, Kengo Suzuki, Jeffrey Comer & Masaaki Tamura. (2022) A Water Extract from Chlorella sorokiniana Cell Walls Stimulates Growth of Bone Marrow Cells and Splenocytes. Nutrients 14:14, pages 2901.
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Haoran Wang, Honghui Liu, Yunfei Guo, Wenjing Zai, Xianghui Li, Wei Xiong, Xiaozhi Zhao, Yingfang Yao, Yiqiao Hu, Zhigang Zou & Jinhui Wu. (2022) Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect. Bioactive Materials 12, pages 97-106.
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Amany Abdel-Rahman Mohamed, Khlood M. El Bohy, Gihan G. Moustafa, Hesham H. Mohammed, Mohamed M. M. Metwally, Heba El Desoukey Mohammed, Mohamed A. Nassan & Taghred M. Saber. (2022) Sustained Functioning Impairments and Oxidative Stress with Neurobehavioral Dysfunction Associated with Oral Nicotine Exposure in the Brain of a Murine Model of Ehrlich Ascites Carcinoma: Modifying the Antioxidant Role of Chlorella vulgaris. Biology 11:2, pages 279.
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Amir Mehdi Hosseini, Seyed Ali Keshavarz, Ensieh Nasli-Esfahani, Fatemehsadat Amiri & Leila Janani. (2021) The effects of Chlorella supplementation on glycemic control, lipid profile and anthropometric measures on patients with type 2 diabetes mellitus. European Journal of Nutrition 60:6, pages 3131-3141.
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Tomohiro Bito, Eri Okumura, Masaki Fujishima & Fumio Watanabe. (2020) Potential of Chlorella as a Dietary Supplement to Promote Human Health. Nutrients 12:9, pages 2524.
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Susumu Ishiguro, Deepa Upreti, Nicole Robben, Riley Burghart, Mayme Loyd, Damilola Ogun, Tran Le, Jennifer Delzeit, Arashi Nakashima, Ravindra Thakkar, Ayaka Nakashima, Kengo Suzuki, Jeffrey Comer & Masaaki Tamura. (2020) Water extract from Euglena gracilis prevents lung carcinoma growth in mice by attenuation of the myeloid-derived cell population. Biomedicine & Pharmacotherapy 127, pages 110166.
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Susumu Ishiguro, Nicole Robben, Riley Burghart, Paige Cote, Sarah Greenway, Ravindra Thakkar, Deepa Upreti, Ayaka Nakashima, Kengo Suzuki, Jeffrey Comer & Masaaki Tamura. (2020) Cell Wall Membrane Fraction of Chlorella sorokiniana Enhances Host Antitumor Immunity and Inhibits Colon Carcinoma Growth in Mice . Integrative Cancer Therapies 19, pages 153473541990055.
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Susumu Ishiguro, Deepthi Uppalapati, Zachary Goldsmith, Dana Robertson, Jacob Hodge, Hayley Holt, Arashi Nakashima, Katie Turner & Masaaki Tamura. (2017) Exopolysaccharides extracted from Parachlorella kessleri inhibit colon carcinoma growth in mice via stimulation of host antitumor immune responses. PLOS ONE 12:4, pages e0175064.
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Sophie Hidalgo-LucasPascale RozanLaetitia Guérin-DeremauxBlandine BaertNicolas ViolleMarie-Hélène Saniez-DegraveJean-François Bisson. (2016) Benefits of Preventive Administration of Chlorella sp. on Visceral Pain and Cystitis Induced by a Single Administration of Cyclophosphamide in Female Wistar Rat . Journal of Medicinal Food 19:5, pages 450-456.
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Julian N. Rosenberg, Naoko Kobayashi, Austin Barnes, Eric A. Noel, Michael J. Betenbaugh & George A. Oyler. (2014) Comparative Analyses of Three Chlorella Species in Response to Light and Sugar Reveal Distinctive Lipid Accumulation Patterns in the Microalga C. sorokiniana. PLoS ONE 9:4, pages e92460.
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Li Li, Wei Li, Yong-ho Kim & Yong Woo Lee. (2013) Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice. Experimental and Toxicologic Pathology 65:1-2, pages 73-80.
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Jung Hyun Kwak, Seung Han Baek, Yongje Woo, Jae Kab Han, Byung Gon Kim, Oh Yoen Kim & Jong Ho Lee. (2012) Beneficial immunostimulatory effect of short-term Chlorella supplementation: enhancement of Natural Killercell activity and early inflammatory response (Randomized, double-blinded, placebo-controlled trial). Nutrition Journal 11:1.
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. 2011. A Guide to Evidence-based Integrative and Complementary Medicine. A Guide to Evidence-based Integrative and Complementary Medicine 200 247 .
Jae-Young Shim, Hye-seoung Shin, Jae-Gab Han, Hyeung-Suk Park, Byung-Lak Lim, Kyung-Won Chung & Ae-Son Om. (2008) Protective Effects of Chlorella vulgaris on Liver Toxicity in Cadmium-Administered Rats . Journal of Medicinal Food 11:3, pages 479-485.
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Kaoru Hazeki, Misako Matsumoto, Ken Kodama, Takashi Ebihara & Tsukasa Seya. 2007. Spirulina in Human Nutrition and Health. Spirulina in Human Nutrition and Health 195 203 .
Hyo-Jin An, Hyun-Myung Choi, Hyeung-Suk Park, Jae-Gab Han, Eun-Hee Lee, Young-Sig Park, Jae-Young Um, Seung-Heon Hong & Hyung-Min Kim. (2006) Oral Administration of Hot Water Extracts of<i> Chlorella vulgaris</i> Increases Physical Stamina in Mice. Annals of Nutrition and Metabolism 50:4, pages 380-386.
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J.A. Kralovec, M.R. Power, F. Liu, E. Maydanski, H.S. Ewart, L.V. Watson, C.J. Barrow & T.J. Lin. (2005) An aqueous Chlorella extract inhibits IL-5 production by mast cells in vitro and reduces ovalbumin-induced eosinophil infiltration in the airway in mice in vivo. International Immunopharmacology 5:4, pages 689-698.
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Suh-Ching Yang. (2005) Apoptosis induced by nucleosides in the human hepatoma HepG2. World Journal of Gastroenterology 11:40, pages 6381.
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Takashi Hasegawa, Shoichiro Kumamoto, Kikuo Nomoto & Yasunobu Yoshikai. 2005. Bioactive Natural Products (Part K). Bioactive Natural Products (Part K) 761 795 .
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Takashi Hasegawa, Tetsuya Matsuguchi, Kiyoshi Noda, Kuniaki Tanaka, Shoichiro Kumamoto, Yukihiro Shoyama & Yasunobu Yoshikai. (2002) Toll-like receptor 2 is at least partly involved in the antitumor activity of glycoprotein from Chlorella vulgaris. International Immunopharmacology 2:4, pages 579-589.
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Tomohiro Hirahashi, Misako Matsumoto, Kaoru Hazeki, Yoshiko Saeki, Michio Ui & Tsukasa Seya. (2002) Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis. International Immunopharmacology 2:4, pages 423-434.
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Kuniaki Tanaka, Yikihiro Shoyama, Akira Yamada, Kiyoshi Noda, Fumiko Konishi & Kikuo Nomoto. 2001. Bioactive Natural Products (Part F). Bioactive Natural Products (Part F) 429 458 .

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