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Research Article

In Vitro Inhibition of Cellular Immune Responses by Benzodiazepines and Pk 11195 Effects on Mitogen-and Alloantigen-driven Lymphocyte Proliferation and on IL-1, IL-2 Synthesis and IL-2 Receptor Expression

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Pages 557-582 | Published online: 28 Sep 2008

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Ricardo Lazzarini, João Palermo-Neto & Benjamin Eurico Malucelli. (2001) REDUCTION OF ACUTE INFLAMMATION IN RATS BY DIAZEPAM: ROLE OF PERIPHERAL BENZODIAZEPINE RECEPTORS AND CORTICOSTERONE. Immunopharmacology and Immunotoxicology 23:2, pages 253-265.
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F.R. Silva & J. Palermo-Neto. (1999) Developmental, Neuro and Immunotoxic Effects of Perinatal Diazepam Treatment in Rats. Immunopharmacology and Immunotoxicology 21:2, pages 247-265.
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Articles from other publishers (20)

Emma L. Sparrow, Sonya James, Khiyam Hussain, Stephen A. Beers, Mark S. Cragg & Yury D. Bogdanov. (2021) Activation of GABA(A) receptors inhibits T cell proliferation. PLOS ONE 16:5, pages e0251632.
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Jessica L Hughes, John S Beech, P Simon Jones, Dechao Wang, David K Menon, Franklin I Aigbirhio, Tim D Fryer & Jean-Claude Baron. (2019) Early-stage 11 C-Flumazenil PET predicts day-14 selective neuronal loss in a rodent model of transient focal cerebral ischemia . Journal of Cerebral Blood Flow & Metabolism 40:10, pages 1997-2009.
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Kenneth M. Rosenberg & Nevil J. Singh. (2019) Mouse T cells express a neurotransmitter-receptor signature that is quantitatively modulated in a subset- and activation-dependent manner. Brain, Behavior, and Immunity 80, pages 275-285.
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B.L.F. Kaplan. 2018. Comprehensive Toxicology. Comprehensive Toxicology 791 825 .
Yannan Zhang, Sifei Yu, Xiaomin Li, Binyan Yang & Changyou Wu. (2017) The ligands of translocator protein inhibit human Th1 responses and the rejection of murine skin allografts. Clinical Science 131:4, pages 297-308.
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Dariusz Andrzejczak. (2011) Padaczka a cytokiny prozapalne. Immunomoduluj?ce w?a?ciwo?ci lek?w przeciwpadaczkowych. Neurologia i Neurochirurgia Polska 45:3, pages 275-285.
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Camila Bento de Lima, Monica Sakai, Andreia Oliveira Latorre, Regina Lucia de Moraes Moreau & João Palermo-Neto. (2010) Effects of different doses and schedules of diazepam treatment on lymphocyte parameters in rats. International Immunopharmacology 10:11, pages 1335-1343.
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Min Wei, Li Li, Rui Meng, Yanying Fan, Yun Liu, Liang Tao, Xianguo Liu & Changyou Wu. (2010) Suppressive effect of diazepam on IFN-? production by human T cells. International Immunopharmacology 10:3, pages 267-271.
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Shiaw-Pyng Wey, Hsin-Ying Wu, Fang-Chia Chang & Tong-Rong Jan. (2008) Methamphetamine and diazepam suppress antigen-specific cytokine expression and antibody production in ovalbumin-sensitized BALB/c mice. Toxicology Letters 181:3, pages 157-162.
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Manuel Freire-Garabal, Milvia Varela, Pilar Riveiro, José Balboa, David Liñares, Paula Mañá, Jose M. Mayán, Manuel Rey-Méndez & Marı́a J. Núñez. (2000) Effects of nefazodone on the immune system of mice. European Neuropsychopharmacology 10:4, pages 255-264.
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J. D. Waterfield, E. G. McGeer & P. L. McGeer. (1999) The peripheral benzodiazepine receptor ligand PK 11195 inhibits arthritis in the MRL-lpr mouse model. Rheumatology 38:11, pages 1068-1073.
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Jardena Nordenberg, Eyal Fenig, Marina Landau, Ronit Weizman & Abraham Weizman. (1999) Effects of psychotropic drugs on cell proliferation and differentiation. Biochemical Pharmacology 58:8, pages 1229-1236.
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Fatima Ammadi, Sa?d Boukhris, Abdelaziz Souizi & G?rard Coudert. (1999) Synth?se d'une nouvelle s?rie de 1,4-benzodiaz?pine-5-ones ? partir des epoxydes cyanoesters. Tetrahedron Letters 40:36, pages 6517-6518.
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Jide Tian, Cindy Chau, Tim G Hales & Daniel L Kaufman. (1999) GABAA receptors mediate inhibition of T cell responses. Journal of Neuroimmunology 96:1, pages 21-28.
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Tanimoto Yutaka, Onishi Yoshiaki, Sato Yutaka & Kizaki Harutoshi. (1999) Benzodiazepine Receptor Agonists Modulate Thymocyte Apoptosis Through Reduction of the Mitochondrial Transmembrane Potential. Japanese Journal of Pharmacology 79:2, pages 177-183.
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Flora Zavala. (1997) Benzodiazepines, anxiety and immunity. Pharmacology & Therapeutics 75:3, pages 199-216.
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Hanna Bessler, Bella Caspi, Moshe Gavish, Moshe Rehavi, Jacob Hart & Ronit Weizman. (1997) Peripheral-type benzodiazepine receptor ligands modulate human natural killer cell activity. International Journal of Immunopharmacology 19:5, pages 249-254.
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M. Schlumpf, R. Parmar, E. E. Bütikofer, S. Inderbitzin, A. R. Salili, A. A. Schreiber, H. R. Ramseier, H. van Loveren & W. Lichtensteiger. 1995. Toxicology in Transition. Toxicology in Transition 261 287 .
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M. Schlumpf, E.E. Bütikofer, A.A. Schreiber, R. Parmar, H.R. Ramseier & W. Lichtensteiger. (1994) Delayed developmental immunotoxicity of prenatal benzodiazepines. Toxicology in Vitro 8:5, pages 1061-1065.
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