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Immunopharmacology and Immunotoxicology Volume 15, 1993 - Issue 2-3
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Research Article

Immunotoxic Effects of Mercuric Compounds on Human Lymphocytes and Monocytes. IV. Alterations in Cellular Glutathione Content

B. J. Shenker Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, 19104-6002
,
C. Rooney Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, 19104-6002
,
L. Vitale And Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, 19104-6002
,
J. S. Mayro Department of Biochemistry, University of Pennsylvania School of Dental Medicine, 4010 Locust Street, Philadelphia, PA, 19104-6002
&
I. M. Shapiro Department of Biochemistry, University of Pennsylvania School of Dental Medicine, 4010 Locust Street, Philadelphia, PA, 19104-6002
Pages 273-290 | Published online: 28 Sep 2008

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Sang Hyun Kim & Raghubir P. Sharma. (2005) Mercury Alters Endotoxin-Induced Inflammatory Cytokine Expression in Liver: Differential Roles of P38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases. Immunopharmacology and Immunotoxicology 27:1, pages 123-135.
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Waldemar Lutz & Wojciech Wasowicz. (2003) Metal-Induced Modulation of Redox Cell-Signaling in the Immune System. Comments on Toxicology 9:1, pages 59-83.
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Eliane Moisan, Sylvie Arbour, Nhi Nguyen, Marie-Josée Hébert, Denis Girard, Jacques Bernier, Michel Fournier & Edouard Kouassi. (2002) PROLONGATION OF HUMAN NEUTROPHIL SURVIVAL BY LOW-LEVEL MERCURY VIA INHIBITION OF SPONTANEOUS APOPTOSIS. Journal of Toxicology and Environmental Health, Part A 65:2, pages 183-203.
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Sa Thompson, Kl Roellich, A Grossmann, Sg Gilbert & Tj Kavanagh. (1998) Alterations in Immune Parameters Associated with Low Level Methylmercury Exposure in Mice. Immunopharmacology and Immunotoxicology 20:2, pages 299-314.
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Articles from other publishers (28)

M. Firoze Khan & Gangduo Wang. (2018) Environmental agents, oxidative stress and autoimmunity. Current Opinion in Toxicology 7, pages 22-27.
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Renee M. Gardner & Jennifer F. Nyland. 2016. Environmental Influences on the Immune System. Environmental Influences on the Immune System 273 302 .
Anselm Mak & Sen Tay. (2014) Environmental Factors, Toxicants and Systemic Lupus Erythematosus. International Journal of Molecular Sciences 15:9, pages 16043-16056.
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EC Somers & BC Richardson. (2014) Environmental exposures, epigenetic changes and the risk of lupus. Lupus 23:6, pages 568-576.
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Janet Kern, Boyd Haley, David Geier, Lisa Sykes, Paul King & Mark Geier. (2013) Thimerosal Exposure and the Role of Sulfation Chemistry and Thiol Availability in Autism. International Journal of Environmental Research and Public Health 10:8, pages 3771-3800.
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Michael Schiraldi & Marc Monestier. (2009) How can a chemical element elicit complex immunopathology? Lessons from mercury-induced autoimmunity. Trends in Immunology 30:10, pages 502-509.
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Jason Y. Chang & Pao-Feng Tsai. (2009) IL-6 release from mouse glia caused by MeHg requires cytosolic phospholipase A2 activation. Neuroscience Letters 461:2, pages 85-89.
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Bruce J. Shenker, Nancy N. Maserejian, Annie Zhang & Sonja McKinlay. (2008) Immune Function Effects of Dental Amalgam in Children. The Journal of the American Dental Association 139:11, pages 1496-1505.
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Jaya Vas & Marc Monestier. (2008) Immunology of Mercury. Annals of the New York Academy of Sciences 1143:1, pages 240-267.
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Jason Y. Chang & Pao-Feng Tsai. (2008) Prevention of methylmercury-induced mitochondrial depolarization, glutathione depletion and cell death by 15-deoxy-delta-12,14-prostaglandin J2. NeuroToxicology 29:6, pages 1054-1061.
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Peter Frisk, Ylva Molin & Nils-Gunnar Ilbäck. (2008) Tissue uptake of mercury is changed during the course of a common viral infection in mice. Environmental Research 106:2, pages 178-184.
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Richard Deth, Christina Muratore, Jorge Benzecry, Verna-Ann Power-Charnitsky & Mostafa Waly. (2008) How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis. NeuroToxicology 29:1, pages 190-201.
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N.G. Pabello & D.A. Lawrence. (2006) Neuroimmunotoxicology: Modulation of neuroimmune networks by toxicants. Clinical Neuroscience Research 6:1-2, pages 69-85.
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Saeko Araragi, Masuo Kondoh, Masaki Kawase, Sayaka Saito, Minoru Higashimoto & Masao Sato. (2003) Mercuric chloride induces apoptosis via a mitochondrial-dependent pathway in human leukemia cells. Toxicology 184:1, pages 1-9.
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Bruce J. Shenker, Lisa Pankoski, Ali Zekavat & Irving M. Shapiro. (2002) Mercury-Induced Apoptosis in Human Lymphocytes: Caspase Activation Is Linked to Redox Status. Antioxidants & Redox Signaling 4:3, pages 379-389.
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M.V Rao, N.J Chinoy, M.B Suthar & M.I Rajvanshi. (2001) Role of ascorbic acid on mercuric chloride-induced genotoxicity in human blood cultures. Toxicology in Vitro 15:6, pages 649-654.
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Bruce J. Shenker, Tai L. Guo & Irving M. Shapiro. (2000) Mercury-Induced Apoptosis in Human Lymphoid Cells: Evidence That the Apoptotic Pathway Is Mercurial Species Dependent. Environmental Research 84:2, pages 89-99.
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Zbigniew Zabiński, Zbigniew DabrowskiPaulin Moszczyński & Jan Rutowski. (2016) The activity of erythrocyte enzymes and basic indices of peripheral blood erythrocytes from workers chronically exposed to mercury vapours. Toxicology and Industrial Health 16:2, pages 211-217.
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Bruce J. Shenker, Tai L. Guo, Insug O & Irving M. Shapiro. (1999) Induction of Apoptosis in Human T-Cells by Methyl Mercury: Temporal Relationship between Mitochondrial Dysfunction and Loss of Reductive Reserve. Toxicology and Applied Pharmacology 157:1, pages 23-35.
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P Brousseau, J Pellerin, Y Morin, D Cyr, B Blakley, H Boermans & M Fournier. (1999) Flow cytometry as a tool to monitor the disturbance of phagocytosis in the clam Mya arenaria hemocytes following in vitro exposure to heavy metals.. Toxicology 142:2, pages 145-156.
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Maria E. Ariza, Gautam N. Bijur & Marshall V. WilliamsMaria E. Ariza, Gautam N. Bijur & Marshall V. Williams. 1999. Environmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity. Environmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity 53 95 .
Tai Liang Guo, Mark A. Miller, Irving M. Shapiro & Bruce J. Shenker. (1998) Mercuric Chloride Induces Apoptosis in Human T Lymphocytes: Evidence of Mitochondrial Dysfunction. Toxicology and Applied Pharmacology 153:2, pages 250-257.
Crossref
Bruce J. Shenker, Tai L. Guo & Irving M. Shapiro. (1998) Low-Level Methylmercury Exposure Causes Human T-Cells to Undergo Apoptosis: Evidence of Mitochondrial Dysfunction. Environmental Research 77:2, pages 149-159.
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Mary Luci de Souza QueirozSocrates Calvoso PenaTereza Sueko Ide SallesEduardo Melo de CapitaniSara Teresinha Olalla Saad. (2016) Abnormal antioxidant system in erythrocytes of mercury-exposed workers. Human & Experimental Toxicology 17:4, pages 225-230.
Crossref
O InSug, Sugandha Datar, Cameron J Koch, Irving M Shapiro & Bruce J Shenker. (1997) Mercuric compounds inhibit human monocyte function by inducing apoptosis: evidence for formation of reactive oxygen species, development of mitochondrial membrane permeability transition and loss of reductive reserve. Toxicology 124:3, pages 211-224.
Crossref
Bruce J. Shenker, Sugandha Datar, Kyle Mansfield & Irving M. Shapiro. (1997) Induction of Apoptosis in Human T-Cells by Organomercuric Compounds: A Flow Cytometric Analysis. Toxicology and Applied Pharmacology 143:2, pages 397-406.
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J Koropatnick & R K Zalups. (2009) Effect of non‐toxic mercury, zinc or cadmium pretreatment on the capacity of human monocytes to undergo lipopolysaccharide‐induced activation. British Journal of Pharmacology 120:5, pages 797-806.
Crossref
David A. Lawrence & Michael J. McCabeJr.Jr.. 1995. Metal Toxicology. Metal Toxicology 305 337 .

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