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Journal of Investigative Surgery Volume 28, 2015 - Issue 1
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ORIGINAL ARTICLES

Cytokine Expression in Human Osteoblasts After Antiseptic Treatment: A Comparative Study Between Polyhexanide and Chlorhexidine

Eric RöhnerDepartment of Orthopaedics, Rudolf-Elle-Hospital, Friedrich-Schiller-University of Jena, Eisenberg, GermanyCorrespondence[email protected]
,
Paula HoffBerlin Brandenburg Center for Regenerative Therapies, Berlin, Germany;Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany
,
Timo GaberBerlin Brandenburg Center for Regenerative Therapies, Berlin, Germany;Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany
,
Annemarie LangBerlin Brandenburg Center for Regenerative Therapies, Berlin, Germany;Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany
,
Pauline VörösDepartment of Traumatology and Orthopaedics, Charité University Hospital, Berlin, Germany
,
Frank ButtgereitBerlin Brandenburg Center for Regenerative Therapies, Berlin, Germany;Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany
,
Carsten PerkaDepartment of Traumatology and Orthopaedics, Charité University Hospital, Berlin, Germany
,
Christoph WindischDepartment of Orthopaedics, Rudolf-Elle-Hospital, Friedrich-Schiller-University of Jena, Eisenberg, Germany
&
Georg MatziolisDepartment of Orthopaedics, Rudolf-Elle-Hospital, Friedrich-Schiller-University of Jena, Eisenberg, Germany
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Pages 1-7 | Received 01 Apr 2014, Accepted 01 Jul 2014, Published online: 05 Aug 2014

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Anton Vitt, Veronica Slizen, Elisabeth A. Boström, Tülay Yucel-Lindberg, Anna Kats, Rachael V. Sugars, Anders Gustafsson & Kåre Buhlin. (2017) Effects of polyhexamethylene guanidine phosphate on human gingival fibroblasts. Acta Odontologica Scandinavica 75:7, pages 524-529.
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Thomas Eberlein, Cornelia Wiegand & Florian H.H. Brill. (2017) According to the Article “Cytokine Expression in Human Osteoblasts After Antiseptic Treatment: A Comparative Study between Polyhexanide and Chlorhexidine” by Röhner E. et al., Journal of Investigative Surgery, 28, 1–7, 2015. Journal of Investigative Surgery 30:1, pages 66-67.
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Eric Röhner, Georg Matziolis & Paula Hoff. (2017) Reply to Letter to the Editor “According to the Article ‘Cytokine Expression in Human Osteoblasts After Antiseptic Treatment:A Comparative Study between Polyhexanide and Chlorhexidine’”. Journal of Investigative Surgery 30:1, pages 68-69.
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Nathalie S. D. Michel, Jürgen R. J. Paletta, Martina Kerwart & Adrian Skwara. (2016) Role of Electrochemically Activated Solution in Asepsis in Osteoblasts and Chondrocytes in vitro. Journal of Investigative Surgery 29:3, pages 157-166.
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Articles from other publishers (12)

Natcha Thongrueang, Shyh-Shyan Liu, Huan-Yu Hsu & Hsu-Hsun Lee. (2022) An in vitro comparison of antimicrobial efficacy and cytotoxicity between povidone-iodine and chlorhexidine for treating clinical endometritis in dairy cows. PLOS ONE 17:7, pages e0271274.
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Łukasz Pałka, Agnieszka Nowakowska-Toporowska & Bartosz Dalewski. (2022) Is Chlorhexidine in Dentistry an Ally or a Foe? A Narrative Review. Healthcare 10:5, pages 764.
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Sabrina Böhle, Eric Röhner, Timo Zippelius, Benjamin Jacob, Georg Matziolis & Sebastian Rohe. (2021) Cytotoxic effect of sodium hypochlorite (Lavanox 0.08%) and chlorhexidine gluconate (Irrisept 0.05%) on human osteoblasts. European Journal of Orthopaedic Surgery & Traumatology 32:1, pages 81-89.
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Z. S. Khabadze, D. S. NazarovaA. A. KulikovaYu. A. GeneralovaE. S. ShilyaevaA. P. Kotelnikova. (2021) Polyhexanide as a new antiseptic composition for a dentist. Endodontics Today 19:4, pages 306-309.
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Jacob F. Markel, Therese Bou-Akl, Paula Dietz & Alan M. Afsari. (2021) The Effect of Different Irrigation Solutions on the Cytotoxicity and Recovery Potential of Human Osteoblast Cells In Vitro. Arthroplasty Today 7, pages 120-125.
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Adaias Oliveira Matos, Amanda Bandeira de Almeida, Thamara Beline, Caroline C. Tonon, Renato Corrêa Viana Casarin, Lester Jack Windsor, Simone Duarte, Francisco Humberto NocitiJr.Jr., Elidiane Cipriano Rangel, Richard L. Gregory & Valentim Adelino Ricardo Barão. (2020) Synthesis of multifunctional chlorhexidine-doped thin films for titanium-based implant materials. Materials Science and Engineering: C 117, pages 111289.
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E. Röhner, B. Jacob, S. Böhle, S. Rohe, B. Löffler, G. Matziolis & T. Zippelius. (2020) Sodium hypochlorite is more effective than chlorhexidine for eradication of bacterial biofilm of staphylococci and Pseudomonas aeruginosa. Knee Surgery, Sports Traumatology, Arthroscopy 28:12, pages 3912-3918.
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In‐Gu Kang, Jinyoung Kim, Suhyung Park, Hyoun‐Ee Kim & Cheol‐Min Han. (2020) PLLA Membrane with Embedded Hydroxyapatite Patterns for Improved Bioactivity and Efficient Delivery of Growth Factor. Macromolecular Bioscience 20:10, pages 2000136.
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Jan Puetzler, Charalampos Zalavras, Thomas F. Moriarty, Michael H.J. Verhofstad, Stephen L. Kates, Michael -J. Raschke, Steffen Rosslenbroich & Willem-J. Metsemakers. (2019) Clinical practice in prevention of fracture-related infection: An international survey among 1197 orthopaedic trauma surgeons. Injury 50:6, pages 1208-1215.
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Flaminia Chellini, Marco Giannelli, Alessia Tani, Lara Ballerini, Larissa Vallone, Daniele Nosi, Sandra Zecchi-Orlandini & Chiara Sassoli. (2017) Mesenchymal stromal cell and osteoblast responses to oxidized titanium surfaces pre-treated with λ = 808 nm GaAlAs diode laser or chlorhexidine: in vitro study. Lasers in Medical Science 32:6, pages 1309-1320.
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Ole Goertz, Henrik Lauer, Tobias Hirsch, Adrien Daigeler, Kamran Harati, Ingo Stricker, Marcus Lehnhardt & Leon von der Lohe. (2016) Evaluation of angiogenesis, epithelialisation and microcirculation after application of polyhexanide, chitosan and sodium chloride in rodents. International Wound Journal 13:6, pages 1161-1167.
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Kosaku Sawada, Jordi Caballé-Serrano, Dieter D. Bosshardt, Benoit Schaller, Richard J. Miron, Daniel Buser & Reinhard Gruber. (2015) Antiseptic solutions modulate the paracrine-like activity of bone chips: differential impact of chlorhexidine and sodium hypochlorite. Journal of Clinical Periodontology 42:9, pages 883-891.
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