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Journal of Investigative Surgery Volume 3, 1990 - Issue 1
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Original Article

A New Liver Perfusion and Preservation System for Transplantation Research in Large Animals

Katsuhiko Yanaga Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
,
Leonard Makowka Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
,
Guy Lebeau Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
,
Ruey Rong Hwang Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
,
Mitsuo Shimada Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
,
Saburo Kakizoe Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
,
A. Jake Demetris Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
&
Thomas E. Starzl Department of Surgery and Pathology, University Health Science Center of Pittsburgh University of Pittsburgh, Falk Clinic 4 West, Pittsburgh, PA, 15213
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Pages 65-75 | Published online: 09 Jul 2009

Citations (18)

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Read on this site (2)

Solly S. Mizrahi, Jon W. Jones & Frederick R. Bentley. (1996) A Facilitated Technique for Hepatectomy of Porcine Liver. Journal of Investigative Surgery 9:5, pages 393-398.
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Denise L. Travis, A. William Paulsen & Yuri Genyk. (1996) Development of an in Situ Isolated Porcine Liver Perfusion Model for Tightly Controlled Physiologic and Pharmacologic Studies. Journal of Investigative Surgery 9:2, pages 131-147.
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Articles from other publishers (16)

Nicola De Stefano, Alberto Calleri, Victor Navarro-Tableros, Federica Rigo, Damiano Patrono & Renato Romagnoli. (2022) State-of-the-Art and Future Directions in Organ Regeneration with Mesenchymal Stem Cells and Derived Products during Dynamic Liver Preservation. Medicina 58:12, pages 1826.
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Laurence Verstraeten & Ina Jochmans. (2022) Sense and Sensibilities of Organ Perfusion as a Kidney and Liver Viability Assessment Platform. Transplant International 35.
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Nicholas GilboTine WylinVeerle HeedfeldIna JochmansJacques PirennePeter FriendDiethard Monbaliu. (2021) Porcine Liver Normothermic Machine Perfusion: Methodological Framework and Potential Pitfalls. Transplantation Direct 8:1, pages e1276.
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Miriam Cortes-Cerisuelo. 2021. Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation. Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation 275 288 .
Mikako GochiFuminori KatoAsuka ToriumiTomoko KawagoeShuichi YotsuyaDaisuke IshiiMasahide OtaniYuji NishikawaHiroyuki FurukawaNaoto Matsuno. (2020) A Novel Preservation Solution Containing Quercetin and Sucrose for Porcine Kidney Transplantation. Transplantation Direct 6:12, pages e624.
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Francesca Maione, Nicholas Gilbo, Silvia Lazzaro, Peter Friend, Giovanni Camussi, Renato Romagnoli, Jacques Pirenne, Ina Jochmans & Diethard Monbaliu. (2018) Porcine Isolated Liver Perfusion for the Study of Ischemia Reperfusion Injury. Transplantation 102:7, pages 1039-1049.
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Clifford Akateh, Eliza W. Beal, Bryan A. Whitson & Sylvester M. Black. (2018) Normothermic Ex-vivo Liver Perfusion and the Clinical Implications for Liver Transplantation. Journal of Clinical and Translational Hepatology 6:3, pages 1-7.
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S.A. Karangwa, P. Dutkowski, P. Fontes, P.J. Friend, J.V. Guarrera, J.F. Markmann, H. Mergental, T. Minor, C. Quintini, M. Selzner, K. Uygun, C.J. Watson & R.J. Porte. (2016) Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines. American Journal of Transplantation 16:10, pages 2932-2942.
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Bo Wang & Jason A. Wertheim. 2016. Translating Regenerative Medicine to the Clinic. Translating Regenerative Medicine to the Clinic 309 313 .
D. Bon, P.-O. Delpech, N. Chatauret, T. Hauet, L. Badet & B. Barrou. (2014) Does machine perfusion decrease ischemia reperfusion injury?. Progrès en Urologie 24, pages S44-S50.
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M Thamara PR Perera, Darius F Mirza & Elwyn Elias. (2009) Liver transplantation: Issues for the next 20âyears. Journal of Gastroenterology and Hepatology 24, pages S124-S131.
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M. Adham, J.M. Sab, C. Ducerf, D. Tassaux, C. Vianey-Saban, M. Chevallier, E. de la Roche, Q.V. Le, T. Bizollon, C. Barakat, G. Debize, M. Vernet, M. Pouyet & J. Baulieux. (1997) Correction of acute liver cell failure disorders through liver xenoperfusion: Experimental study. Transplantation Proceedings 29:7, pages 3013-3014.
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Takahiko Seo, Hisami Ando, Yoshio Watanabe, Fujio Ito, Satoshi Iino, Hiroyuki Takagi & Takahiro Ito. (1997) Biochemical and morphological changes in the liver during isolated liver perfusion with double bypass using automatic blood pumps. Journal of Pediatric Surgery 32:1, pages 75-79.
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Hidetoshi Itasaka, Keiji Kishikawa, Taketoshi Suehiro, Katsuhiko Yanaga, Mitsuo Shimada, Hidefumi Higashi, Saburo Kakizoe, Tetsuo Ikeda, Shigeki Wakiyama & Keizo Sugimachi. (1994) Serum hyaluronic acid for the assessment of graft viability in porcine liver transplantation. Surgery Today 24:8, pages 719-724.
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P. Neuhaus & G. Blumhardt. (2018) Extracorporeal Liver Perfusion: Applications of an Improved Model for Experimental Studies of the Liver. The International Journal of Artificial Organs 16:10, pages 729-739.
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Mitsuo Shimada, Katsuhiko Yanaga, Keiji Kishikawa, Saburo Kakizoe, Hidetoshi Itasaka, Tetsuo Ikeda, Taketoshi Suehiro & Kcizo Sugimachi. (1993) Prediction of hepatic graft viability before reperfusion: an analysis of effluent from porcine allografts. Transplant International 6:1, pages 4-7.
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