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Inhalation Toxicology
International Forum for Respiratory Research
Volume 23, 2011 - Issue 1
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Research Article

Attempts to counteract phosgene-induced acute lung injury by instant high-dose aerosol exposure to hexamethylenetetramine, cysteine or glutathione

Jürgen PauluhnInstitute of Toxicology, Bayer HealthCare AG, 42096 Wuppertal, GermanyCorrespondence[email protected]
&
Chun Xue HaiDepartment of Toxicology, Fourth Military Medical University, Xi’an, People’s Republic of China
Pages 58-64 | Received 14 Oct 2010, Accepted 17 Nov 2010, Published online: 12 Jan 2011

Citations (15)

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Jie Shen, Jing Wang, Yi-Ru Shao, Dai-Kun He, Lin Zhang, Lubna Nadeem & Guoxiong Xu. (2013) Adenovirus-delivered angiopoietin-1 treatment for phosgene-induced acute lung injury. Inhalation Toxicology 25:5, pages 272-279.
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Wen-Li Li, Chun-Xu Hai & Jürgen Pauluhn. (2011) Inhaled nitric oxide aggravates phosgene model of acute lung injury. Inhalation Toxicology 23:13, pages 842-852.
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Articles from other publishers (13)

Juergen Pauluhn. (2023) Pathogenetic role of alveolar surfactant depleted by phosgene: Biophysical mechanisms and peak inhalation exposure metrics. Regulatory Toxicology and Pharmacology 143, pages 105441.
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M. Pesonen & K. Vähäkangas. (2020) Chloropicrin-induced toxicity in the respiratory system. Toxicology Letters 323, pages 10-18.
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C. Steiner, C. Eisenhawer & R. Merget. (2019) Lungenschädigung durch akute SchadstoffinhalationLung injury due to acute inhalation of hazardous substances. Der Pneumologe 16:3, pages 160-167.
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Derek L. Eisnor & Brent W. Morgan. 2019. Ophthalmology in Military and Civilian Casualty Care. Ophthalmology in Military and Civilian Casualty Care 171 208 .
Rachel Rendell, Sarah Fairhall, Stuart Graham, Steve Rutter, Philippa Auton, Adam Smith, Rosi Perrott & Bronwen Jugg. (2018) Assessment of N -acetylcysteine as a therapy for phosgene-induced acute lung injury. Toxicology Letters 290, pages 145-152.
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Wenli Li & Juergen Pauluhn. (2017) Phosgene‐induced acute lung injury (ALI): differences from chlorine‐induced ALI and attempts to translate toxicology to clinical medicine. Clinical and Translational Medicine 6:1.
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Wenli Li, Martin Rosenbruch & Jürgen Pauluhn. (2015) Effect of PEEP on phosgene-induced lung edema: Pilot study on dogs using protective ventilation strategies. Experimental and Toxicologic Pathology 67:2, pages 109-116.
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Sa Luo, Hubert Trübel, Chen Wang & Jürgen Pauluhn. (2014) Phosgene- and chlorine-induced acute lung injury in rats: Comparison of cardiopulmonary function and biomarkers in exhaled breath. Toxicology 326, pages 109-118.
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Jie Shen, Zhengyi Gan, Jie Zhao, Liming Zhang & Guoxiong Xu. (2012) Ulinastatin reduces pathogenesis of phosgene-induced acute lung injury in rats. Toxicology and Industrial Health 30:9, pages 785-793.
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Fangfang Liu, Jürgen Pauluhn, Hubert Trübel & Chen Wang. (2014) Single high-dose dexamethasone and sodium salicylate failed to attenuate phosgene-induced acute lung injury in rats. Toxicology 315, pages 17-23.
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Wenli Li, Fangfang Liu, Chen Wang, Hubert Truebel & Juergen Pauluhn. (2013) Novel Insights Into Phosgene-Induced Acute Lung Injury in Rats: Role of Dysregulated Cardiopulmonary Reflexes and Nitric Oxide in Lung Edema Pathogenesis. Toxicological Sciences 131:2, pages 612-628.
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Paul D. Tourigny & Chris Hall. (2012) Diagnosis and Management of Environmental Thoracic Emergencies. Emergency Medicine Clinics of North America 30:2, pages 501-528.
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Vassilissa Vinogradoff, Albert Rimola, Fabrice Duvernay, Gregoire Danger, Patrice Theulé & Thierry Chiavassa. (2012) The mechanism of hexamethylenetetramine (HMT) formation in the solid state at low temperature. Physical Chemistry Chemical Physics 14:35, pages 12309.
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