Advanced search
Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 24, 2012 - Issue 7
Submit an article Journal homepage
332
Views
38
CrossRef citations to date
0
Altmetric
Research Article

Pulmonary and cardiovascular responses of rats to inhalation of a commercial antimicrobial spray containing titanium dioxide nanoparticles

W. McKinneyHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
M. JacksonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
T. M. SagerHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
J. S. ReynoldsHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
B. T. ChenHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
A. AfshariHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
K. KrajnakHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
S. WaughHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
C. JohnsonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
R. R. MercerHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
D. G. FrazerHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
,
T. A. ThomasU.S. Consumer Product Safety Commission, Bethesda, MD, USA
&
V. CastranovaHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USACorrespondence[email protected]
 show all
Pages 447-457 | Received 21 Dec 2011, Accepted 11 Apr 2012, Published online: 30 May 2012

Citations (38)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (10)

K. Krajnak, S. Waugh, Ab Stefaniak, D Schwegler-Berry, Ka Roach, M Barger & Jr. Roberts. (2019) Exposure to graphene nanoparticles induces changes in measures of vascular/renal function in a load and form-dependent manner in mice. Journal of Toxicology and Environmental Health, Part A 82:12, pages 711-726.
Read now
W. Kyle Mandler, Chaolong Qi, Marlene S. Orandle, Khachatur Sarkisian, Robert R. Mercer, Aleksandr B. Stefaniak, Alycia K. Knepp, Lauren N. Bowers, Lori A. Battelli, Justine Shaffer, Sherri A. Friend, Yong Qian & Jennifer D. Sisler. (2019) Mouse pulmonary response to dust from sawing Corian®, a solid-surface composite material. Journal of Toxicology and Environmental Health, Part A 82:11, pages 645-663.
Read now
Jennifer D. Sisler, Chaolong Qi, Walter McKinney, Justine Shaffer, Michael Andrew, Taekhee Lee, Treye Thomas, Vincent Castranova, Robert R. Mercer & Yong Qian. (2018) Physical chemical properties and cell toxicity of sanding copper-treated lumber. Journal of Occupational and Environmental Hygiene 15:4, pages 311-321.
Read now
Zhen Yan, Wenjun Wang, Yongjun Wu, Wei Wang, Bing Li, Ning Liang & Weidong Wu. (2017) Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo. International Journal of Nanomedicine 12, pages 4433-4442.
Read now
Michael R. Cooper, Gavin H. West, Leonard G. Burrelli, Daniel Dresser, Kelsey N. Griffin, Alan M. Segrave, Jon Perrenoud & Bruce E. Lippy. (2017) Inhalation exposure during spray application and subsequent sanding of a wood sealant containing zinc oxide nanoparticles. Journal of Occupational and Environmental Hygiene 14:7, pages 510-522.
Read now
Bean T. Chen, Diane Schwegler-Berry, Amy Cumpston, Jared Cumpston, Sherri Friend, Samuel Stone & Michael Keane. (2016) Performance of a scanning mobility particle sizer in measuring diverse types of airborne nanoparticles: Multi-walled carbon nanotubes, welding fumes, and titanium dioxide spray. Journal of Occupational and Environmental Hygiene 13:7, pages 501-518.
Read now
Peter Møller, Daniel Vest Christophersen, Nicklas Raun Jacobsen, Astrid Skovmand, Ana Cecília Damião Gouveia, Maria Helena Guerra Andersen, Ali Kermanizadeh, Ditte Marie Jensen, Pernille Høgh Danielsen, Martin Roursgaard, Kim Jantzen & Steffen Loft. (2016) Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials. Critical Reviews in Toxicology 46:5, pages 437-476.
Read now
Christian Riebeling, Andreas Luch & Mario Enrico Götz. (2016) Comparative modeling of exposure to airborne nanoparticles released by consumer spray products. Nanotoxicology 10:3, pages 343-351.
Read now
Rona M. Silva, Christel TeeSy, Lisa Franzi, Alex Weir, Paul Westerhoff, James E. Evans & Kent E. Pinkerton. (2013) Biological Response to Nano-Scale Titanium Dioxide (TiO2): Role of Particle Dose, Shape, and Retention. Journal of Toxicology and Environmental Health, Part A 76:16, pages 953-972.
Read now
Jenny R. Roberts, Walter McKinney, Hong Kan, Kristine Krajnak, David G. Frazer, Treye A. Thomas, Stacey Waugh, Allison Kenyon, Robert I. MacCuspie, Vincent A. Hackley & Vincent Castranova. (2013) Pulmonary and Cardiovascular Responses of Rats to Inhalation of Silver Nanoparticles. Journal of Toxicology and Environmental Health, Part A 76:11, pages 651-668.
Read now

Articles from other publishers (28)

Todd R. Harris, Julie A. Griffith, Colleen E. C. Clarke, Krista L. Garner, Elizabeth C. Bowdridge, Evan DeVallance, Kevin J. Engles, Thomas P. Batchelor, William T. Goldsmith, Kim Wix, Timothy R. Nurkiewicz & Amy A. Rand. (2023) Distinct profiles of oxylipid mediators in liver, lung, and placenta after maternal nano-TiO 2 nanoparticle inhalation exposure . Environmental Science: Advances 2:5, pages 740-748.
Crossref
Vuk Uskoković. (2023) Lessons from the history of inorganic nanoparticles for inhalable diagnostics and therapeutics. Advances in Colloid and Interface Science 315, pages 102903.
Crossref
Kristine Krajnak, Kristen A. Russ, Walter McKinney, Stacey Waugh, Wen Zheng, Hong Kan, Michael L. Kashon, Jared Cumpston & Jeffrey S. Fedan. (2022) Biological effects of crude oil vapor. IV. Cardiovascular effects. Toxicology and Applied Pharmacology 447, pages 116071.
Crossref
Sara B. Fournier, Vincent Lam, Michael J. Goedken, Laura Fabris & Phoebe A. Stapleton. (2021) Development of coronary dysfunction in adult progeny after maternal engineered nanomaterial inhalation during gestation. Scientific Reports 11:1.
Crossref
Ashley Cox, Pranav Chandra & Nilesh Sharma. 2021. Nanomaterial Biointeractions at the Cellular, Organismal and System Levels. Nanomaterial Biointeractions at the Cellular, Organismal and System Levels 3 51 .
Kristen A. Russ, Janet A. Thompson, Jeffrey S. Reynolds, Robert R. Mercer, Dale W. Porter, Walter McKinney, Richard D. Dey, Mark Barger, Jared Cumpston, Thomas P. Batchelor, Michael L. Kashon, Vamsi Kodali, Mark C. Jackson, Krishnan Sriram & Jeffrey S. Fedan. (2020) Biological effects of inhaled hydraulic fracturing sand dust. IV. Pulmonary effects. Toxicology and Applied Pharmacology 409, pages 115284.
Crossref
Zhen Luo, Zhuoqing Li, Zhe Xie, Inna M. Sokolova, Lan Song, Willie J. G. M. Peijnenburg, Menghong Hu & Youji Wang. (2020) Rethinking Nano‐TiO 2 Safety: Overview of Toxic Effects in Humans and Aquatic Animals . Small 16:36, pages 2002019.
Crossref
Yoann Montigaud, Sophie Périnel-Ragey, Laurent Plantier, Lara Leclerc, Clémence Goy, Anthony Clotagatide, Nathalie Prévôt & Jérémie Pourchez. (2019) Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies. Scientific Reports 9:1.
Crossref
S. B. Fournier, S. Kallontzi, L. Fabris, C. Love & P. A. Stapleton. (2019) Effect of Gestational Age on Maternofetal Vascular Function Following Single Maternal Engineered Nanoparticle Exposure. Cardiovascular Toxicology 19:4, pages 321-333.
Crossref
Yoann Montigaud, Sophie Périnel, Jean-Christophe Dubus, Lara Leclerc, Marie Suau, Clémence Goy, Anthony Clotagatide, Nathalie Prévôt & Jérémie Pourchez. (2019) Development of an ex vivo respiratory pediatric model of bronchopulmonary dysplasia for aerosol deposition studies. Scientific Reports 9:1.
Crossref
Zhangjian Chen, Di Zhou, Yun Wang, Lin Zhao, Guiping Hu, Jiaxing Liu, Huimin Feng, Changmao Long, Tenglong Yan, Shupei Zhou & Guang Jia. (2018) Combined effect of titanium dioxide nanoparticles and glucose on the cardiovascular system in young rats after oral administration. Journal of Applied Toxicology 39:4, pages 590-602.
Crossref
Robert R. Mercer, James F. Scabilloni, Liying Wang, Lori A. Battelli, James M. Antonini, Jenny R. Roberts, Yong Qian, Jennifer D. Sisler, Vincent Castranova, Dale W. Porter & Ann F. Hubbs. (2017) The Fate of Inhaled Nanoparticles: Detection and Measurement by Enhanced Dark-field Microscopy. Toxicologic Pathology 46:1, pages 28-46.
Crossref
Sophie Perinel, Jérémie Pourchez, Lara Leclerc, John Avet, Marc Durand, Nathalie Prévôt, Michèle Cottier & Jean M. Vergnon. (2017) Development of an ex vivo human-porcine respiratory model for preclinical studies. Scientific Reports 7:1.
Crossref
Sophie Perinel, Lara Leclerc, Nathalie Prévôt, Agathe Deville, Michèle Cottier, Marc Durand, Jean-Michel Vergnon & Jérémie Pourchez. (2016) Micron-sized and submicron-sized aerosol deposition in a new ex vivo preclinical model. Respiratory Research 17:1.
Crossref
F. U. Rehman, C. Zhao, H. Jiang & X. Wang. (2016) Biomedical applications of nano-titania in theranostics and photodynamic therapy. Biomaterials Science 4:1, pages 40-54.
Crossref
Ashok K. Singh. 2016. Engineered Nanoparticles. Engineered Nanoparticles 451 514 .
Jennifer D. Sisler, Ruibin Li, Walter McKinney, Robert R. Mercer, Zhaoxia Ji, Tian Xia, Xiang Wang, Justine Shaffer, Marlene Orandle, Amy L. Mihalchik, Lori Battelli, Bean T. Chen, Michael Wolfarth, Michael E. Andrew, Diane Schwegler-Berry, Dale W. Porter, Vincent Castranova, Andre Nel & Yong Qian. (2016) Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle and Fibre Toxicology 13:1.
Crossref
Zhangjian Chen, Yun Wang, Lin Zhuo, Shi Chen, Lin Zhao, Xianguo Luan, Haifang Wang & Guang Jia. (2015) Effect of titanium dioxide nanoparticles on the cardiovascular system after oral administration. Toxicology Letters 239:2, pages 123-130.
Crossref
Elyse Julian, Andrea M. Palestro & Jacqueline A. Thomas. (2015) Pediatric Sunscreen and Sun Safety Guidelines. Clinical Pediatrics 54:12, pages 1133-1140.
Crossref
Stefan Rupf, Hendrik Berger, Axel Buchter, Volker Harth, Mei Fang Ong & Matthias Hannig. (2014) Exposure of patient and dental staff to fine and ultrafine particles from scanning spray. Clinical Oral Investigations 19:4, pages 823-830.
Crossref
Andrea L. Armstead, Valerie C. Minarchick, Dale W. Porter, Timothy R. Nurkiewicz & Bingyun Li. (2015) Acute Inflammatory Responses of Nanoparticles in an Intra-Tracheal Instillation Rat Model. PLOS ONE 10:3, pages e0118778.
Crossref
Alexandra Noël & Ginette Truchon. (2015) Inhaled Titanium Dioxide Nanoparticles: A Review of Their Pulmonary Responses with Particular Focus on the Agglomeration State. Nano LIFE 05:01, pages 1450008.
Crossref
Huiting Qiao, Wenyong Liu, Hongyu Gu, Daifa Wang & Yu Wang. (2015) The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation. Journal of Nanomaterials 2015, pages 1-8.
Crossref
Robert R. Mercer & James D. Crapo. 2015. Comparative Biology of the Normal Lung. Comparative Biology of the Normal Lung 93 104 .
Alexandra Noël, Michel Charbonneau, Yves Cloutier, Robert Tardif & Ginette Truchon. (2013) Rat pulmonary responses to inhaled nano-TiO2: effect of primary particle size and agglomeration state. Particle and Fibre Toxicology 10:1.
Crossref
Ann F. Hubbs, Linda M. Sargent, Dale W. Porter, Tina M. Sager, Bean T. Chen, David G. Frazer, Vincent Castranova, Krishnan Sriram, Timothy R. Nurkiewicz, Steven H. Reynolds, Lori A. Battelli, Diane Schwegler-Berry, Walter McKinney, Kara L. Fluharty & Robert R. Mercer. (2013) Nanotechnology: Toxicologic Pathology. Toxicologic Pathology 41:2, pages 395-409.
Crossref
Robert R Mercer, James F Scabilloni, Ann F Hubbs, Liying Wang, Lori A Battelli, Walter McKinney, Vincent Castranova & Dale W Porter. (2013) Extrapulmonary transport of MWCNT following inhalation exposure. Particle and Fibre Toxicology 10:1, pages 38.
Crossref
Patrick T. O'Shaughnessy. (2013) Occupational health risk to nanoparticulate exposure. Environ. Sci.: Processes Impacts 15:1, pages 49-62.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.