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Inhalation Toxicology
International Forum for Respiratory Research
Volume 24, 2012 - Issue 11
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Research Article

Development of multi-route physiologically-based pharmacokinetic models for ethanol in the adult, pregnant, and neonatal rat

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Pages 698-722 | Received 19 Apr 2012, Accepted 09 Jul 2012, Published online: 06 Sep 2012

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Sheppard A. Martin, Wendy M. Oshiro, Paul A. Evansky, Laura L. Degn, Allen D. Ledbetter, Jermaine Ford, Q. Todd Krantz, William R. LeFew, Tracey E. Beasley, Hisham El-Masri, Eva D. McLanahan, William K. Boyes & Philip J. Bushnell. (2014) Use of novel inhalation kinetic studies to refine physiologically-based pharmacokinetic models for ethanol in non-pregnant and pregnant rats. Inhalation Toxicology 26:10, pages 598-619.
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Micah N. Jasper, Sheppard A. Martin, Wendy M. Oshiro, Jermaine Ford, Philip J. Bushnell & Hisham El-Masri. (2016) Application of Biologically Based Lumping To Investigate the Toxicokinetic Interactions of a Complex Gasoline Mixture. Environmental Science & Technology 50:6, pages 3231-3238.
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David W. Herr, Danielle L. Freeborn, Laura Degn, Sheppard A. Martin, Jayna Ortenzio, Lara Pantlin, Charles W. Hamm & William K. Boyes. (2016) Neurophysiological assessment of auditory, peripheral nerve, somatosensory, and visual system function after developmental exposure to gasoline, E15, and E85 vapors. Neurotoxicology and Teratology 54, pages 78-88.
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Philip J. Bushnell. (2015) Testing for cognitive function in animals in a regulatory context. Neurotoxicology and Teratology 52, pages 68-77.
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S.R. Crowell, J.N. Smith, J.A. Creim, W. Faber & J.G. Teeguarden. (2015) Physiologically based pharmacokinetic modeling of ethyl acetate and ethanol in rodents and humans. Regulatory Toxicology and Pharmacology 73:1, pages 452-462.
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Andrew Maier, Jerald L. Ovesen, Casey L. Allen, Raymond G. York, Bernard K. Gadagbui, Christopher R. Kirman, Torka Poet & Antonio Quiñones-Rivera. (2015) Safety assessment for ethanol-based topical antiseptic use by health care workers: Evaluation of developmental toxicity potential. Regulatory Toxicology and Pharmacology 73:1, pages 248-264.
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W.M. Oshiro, T.E. Beasley, K.L. McDaniel, P.A. Evansky, S.A. Martin, V.C. Moser, M.E. Gilbert & P.J. Bushnell. (2015) Prenatal exposure to vapors of gasoline–ethanol blends causes few cognitive deficits in adult rats. Neurotoxicology and Teratology 49, pages 59-73.
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Sheppard A. Martin, Eva D. McLanahan, Philip J. Bushnell, E. Sidney HunterIIIIII & Hisham El-Masri. (2015) Species Extrapolation of Life-Stage Physiologically-Based Pharmacokinetic (PBPK) Models to Investigate the Developmental Toxicology of Ethanol Using In vitro to In vivo (IVIVE) Methods. Toxicological Sciences 143:2, pages 512-535.
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Linda G. Roberts, Thomas M. Gray, Gary W. Trimmer, Robert M. Parker, F. Jay Murray, Ceinwen A. Schreiner & Charles R. Clark. (2014) Health assessment of gasoline and fuel oxygenate vapors: Developmental toxicity in rats. Regulatory Toxicology and Pharmacology 70:2, pages S69-S79.
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W.M. Oshiro, T.E. Beasley, K.L. McDaniel, M.M. Taylor, P. Evansky, V.C. Moser, M.E. Gilbert & P.J. Bushnell. (2014) Selective cognitive deficits in adult rats after prenatal exposure to inhaled ethanol. Neurotoxicology and Teratology 45, pages 44-58.
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Martin H. Plawecki & David W. Crabb. 2014. Alcohol and the Nervous System. Alcohol and the Nervous System 55 69 .

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