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Inhalation Toxicology
International Forum for Respiratory Research
Volume 26, 2014 - Issue 7
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Research Article

Acute pulmonary toxicity following inhalation exposure to aerosolized VX in anesthetized rats

Xinqi PengAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
,
Michael W. PerkinsAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
,
Jannitt SimonsAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
,
Alicia M. WitriolAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
,
Ashley M. RodriguezAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
,
Brittany M. BenjaminAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
,
Jennifer DevorakAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSA
&
Alfred M. SciutoAnalytical Toxicology Division, Medical Toxicology Branch, United States Army Medical Research Institute of Chemical Defense Aberdeen Proving Ground, MDUSACorrespondence[email protected]
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Pages 371-379 | Received 07 Jan 2014, Accepted 25 Feb 2014, Published online: 25 Apr 2014

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E. Wigenstam, E. Artursson, A. Bucht & L. Thors. (2023) Pharmacological prophylaxis with pyridostigmine bromide against nerve agents adversely impact on airway function in an ex vivo rat precision-cut lung slice model. Toxicology Mechanisms and Methods 33:9, pages 732-740.
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Alfred M. Sciuto & Xinqi Peng. (2018) Pulmonary toxicity following inhalation exposure to VX in anesthetized rats: Possible roles for compromised immunity and oxidative stress-induced lung injury. Experimental Lung Research 44:8-9, pages 379-396.
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Michael W. Perkins, Benjamin Wong, Ashley Rodriguez, Jennifer Devorak & Alfred M. Sciuto. (2015) Measurement of various respiratory dynamics parameters following acute inhalational exposure to soman vapor in conscious rats. Inhalation Toxicology 27:9, pages 432-439.
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Articles from other publishers (8)

Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Marcio de Araujo Furtado, Volodymyr I. Pidoplichko & Maria F. M. Braga. (2023) Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition. Toxics 11:10, pages 866.
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E. Wigenstam, E. Forsberg, A. Bucht & L. Thors. (2021) Efficacy of atropine and scopolamine on airway contractions following exposure to the nerve agent VX. Toxicology and Applied Pharmacology 419, pages 115512.
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Vassiliki Aroniadou-Anderjaska, James P. Apland, Taiza H. Figueiredo, Marcio De Araujo Furtado & Maria F. Braga. (2020) Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasures. Neuropharmacology 181, pages 108298.
Crossref
Alfred M. Sciuto & Urmila P. Kodavanti. 2020. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 515 544 .
E. Bloch-Shilderman, G. Yacov, L. Cohen, I. Egoz, H. Gutman, R. Gez, I. Rabinovitz & U. Nili. (2019) Repetitive antidotal treatment is crucial in eliminating eye pathology, respiratory toxicity and death following whole-body VX vapor exposure in freely moving rats. Archives of Toxicology 93:5, pages 1365-1384.
Crossref
E. Bloch-Shilderman, I. Rabinovitz, I. Egoz, G. Yacov, N. Allon & U. Nili. (2017) Determining a threshold sub-acute dose leading to minimal physiological alterations following prolonged exposure to the nerve agent VX in rats. Archives of Toxicology 92:2, pages 873-892.
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Eleanor M. Summerhill, Gary W. Hoyle, Sven-Eric Jordt, Bronwen J. Jugg, James G. Martin, Sadis Matalon, Steven E. Patterson, David J. Prezant, Alfred M. Sciuto, Erik R. Svendsen, Carl W. White & Livia A. Veress. (2017) An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters. Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness. Annals of the American Thoracic Society 14:6, pages 1060-1072.
Crossref
Alfred M. Sciuto & Urmila P. Kodavanti. 2015. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 489 518 .

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