498
Views
37
CrossRef citations to date
0
Altmetric
Research Paper

Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice

, &
Pages 366-375 | Received 26 Dec 2014, Accepted 14 Oct 2015, Published online: 25 Nov 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Mariarosaria Calvello, Maria Chiara Flore & Luca Richeldi. (2019) Novel drug targets in idiopathic pulmonary fibrosis. Expert Opinion on Orphan Drugs 7:3, pages 125-146.
Read now
Riccardo Inchingolo, Carola Condoluci, Andrea Smargiassi, Annelisa Mastrobattista, Cristina Boccabella, Alessia Comes, Nicoletta Golfi & Luca Richeldi. (2017) Are newly launched pharmacotherapies efficacious in treating idiopathic pulmonary fibrosis? Or is there still more work to be done?. Expert Opinion on Pharmacotherapy 18:15, pages 1583-1594.
Read now
Francesco Varone, Giuliano Montemurro, Francesco Macagno, Mariarosaria Calvello, Emanuele Conte, Enrica Intini, Bruno Iovene, Paolo Maria Leone, Pier-Valerio Mari & Luca Richeldi. (2017) Investigational drugs for idiopathic pulmonary fibrosis. Expert Opinion on Investigational Drugs 26:9, pages 1019-1031.
Read now
Francesco Macagno, Francesco Varone, Paolo Maria Leone, Pier-Valerio Mari, Loredana Panico, Ludovica Berardini & Luca Richeldi. (2017) New treatment directions for IPF: current status of ongoing and upcoming clinical trials. Expert Review of Respiratory Medicine 11:7, pages 533-548.
Read now
Adel Mohammadalipour, Jamshid Karimi, Iraj Khodadadi, Ghasem Solgi, Mohammad Hashemnia, Nasrin Sheikh & Majid Bahabadi. (2017) Dasatinib prevent hepatic fibrosis induced by carbon tetrachloride (CCl4) via anti-inflammatory and antioxidant mechanism. Immunopharmacology and Immunotoxicology 39:1, pages 19-27.
Read now

Articles from other publishers (32)

Aarti Jagannath, Lewis Taylor, Yining Ru, Zeinab Wakaf, Kayomavua Akpobaro, Sridhar Vasudevan & Russell G. Foster. (2023) The multiple roles of salt-inducible kinases in regulating physiology. Physiological Reviews 103:3, pages 2231-2269.
Crossref
Liangneng Zou, Dequn Hong, Kecong Li & Bingyuan Jiang. (2022) Salt-inducible kinase 2 (SIK2) inhibitor ARN-3236 attenuates bleomycin-induced pulmonary fibrosis in mice. BMC Pulmonary Medicine 22:1.
Crossref
Lei Wang, Mei Shao, Wei Jiang & Yangfeng Huang. (2022) Resveratrol alleviates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition and down-regulating TLR4/NF-κB and TGF-β1/smad3 signalling pathways in rats. Tissue and Cell 79, pages 101953.
Crossref
Manuel van Gijsel-Bonnello, Nicola J. Darling, Takashi Tanaka, Samuele Di Carmine, Francesco Marchesi, Sarah Thomson, Kristopher Clark, Mariola Kurowska-Stolarska, Henry J. McSorley, Philip Cohen & J. Simon C. Arthur. (2022) Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury. Journal of Biological Chemistry 298:12, pages 102644.
Crossref
Ozgecan Kayalar & Fusun Oztay. (2022) CGRP induces myofibroblast differentiation and the production of extracellular matrix in MRC5s via autocrine and paracrine signalings. Journal of Biochemical and Molecular Toxicology 36:12.
Crossref
Merve Yildirim, Ozgecan Kayalar, Ersan Atahan & Fusun Oztay. (2022) Atorvastatin attenuates pulmonary fibrosis in mice and human lung fibroblasts, by the regulation of myofibroblast differentiation and apoptosis. Journal of Biochemical and Molecular Toxicology 36:7.
Crossref
Bangrong Cai, Liu Yang, Young Do Jung, Ying Zhang, Xinguang Liu, Peng Zhao & Jiansheng Li. (2022) PTEN: An Emerging Potential Target for Therapeutic Intervention in Respiratory Diseases. Oxidative Medicine and Cellular Longevity 2022, pages 1-26.
Crossref
Lydia Ntari, Christoforos Nikolaou, Ksanthi Kranidioti, Dimitra Papadopoulou, Eleni Christodoulou-Vafeiadou, Panagiotis Chouvardas, Florian Meier, Christina Geka, Maria C. Denis, Niki Karagianni & George Kollias. (2021) Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment. Journal of Translational Medicine 19:1.
Crossref
Amitava Mukherjee, Michael W. Epperly, Donna Shields, Wen Hou, Renee Fisher, Diala Hamade, Hong Wang, M. Saiful Huq, Riyue Bao, Tracy Tabib, Daisy Monier, Simon Watkins, Michael Calderon & Joel S. Greenberger. (2021) Ionizing irradiation-induced Fgr in senescent cells mediates fibrosis. Cell Death Discovery 7:1.
Crossref
Zishuang Liu, Shanshan Chen, Xinfeng Zhang, Fangfang Liu, Kai Yang, Ge Du & Xi Rui. (2021) Dasatinib protects against acute respiratory distress syndrome via Nrf2‐regulated M2 macrophages polarization . Drug Development Research 82:8, pages 1247-1257.
Crossref
Nabila M.E. Hassan, George S.G. Shehatou, Hany Ibrahim Kenawy & Eman Said. (2021) Dasatinib mitigates renal fibrosis in a rat model of UUO via inhibition of Src/STAT-3/NF-κB signaling. Environmental Toxicology and Pharmacology 84, pages 103625.
Crossref
Shunichiro Ueda, Betty M. Nunn, Rajat Chauhan, Kevin McDonald, Henry J. Kaplan, Martin G. O’Toole & Shigeo Tamiya. (2021) Sustained dasatinib treatment prevents early fibrotic changes following ocular trauma. Graefe's Archive for Clinical and Experimental Ophthalmology 259:5, pages 1103-1111.
Crossref
Hassan Reda Hassan Elsayed, Mohammad El-Nablaway, Basma H. Othman, Asim Mohammed Abdalla, Eman Mohammad El Nashar, Mostafa Mohammed Abd-Elmonem & Randa El-Gamal. (2021) Can Dasatinib Ameliorate the Hepatic changes, Induced by Long Term Western Diet, in Mice?. Annals of Anatomy - Anatomischer Anzeiger 234, pages 151626.
Crossref
Ozgecan Kayalar, Fusun Oztay & Hurrem Gul Ongen. (2020) Gastrin-releasing peptide induces fibrotic response in MRC5s and proliferation in A549s. Cell Communication and Signaling 18:1.
Crossref
Fusun Oztay, Sevim Tunali, Ozgecan Kayalar & Refiye Yanardag. (2020) The protective effect of vitamin U on valproic acid‐induced lung toxicity in rats via amelioration of oxidative stress. Journal of Biochemical and Molecular Toxicology 34:12.
Crossref
Hang Li, Caiping Zhao, Ye Tian, Juan Lu, Guiyu Zhang, Shuang Liang, Dongfeng Chen, Xiaohong Liu, Weihong Kuang & Meiling Zhu. (2020) Src family kinases and pulmonary fibrosis: A review. Biomedicine & Pharmacotherapy 127, pages 110183.
Crossref
Zhenglin Piao, Jae-Kuk Yoo, Byeong-Wook Park, Seung Bo Seo, Sung-Jin Park, Ha-Young Jeon, Md. Mahbubur Rahman, Namsoo Kim & Sokho Kim. (2020) Therapeutic effects of shibashin misena® against fine-dust-induced pulmonary disorders in mice. Biomedicine & Pharmacotherapy 125, pages 110018.
Crossref
Marcelo B. Cavalcante, Tatiana D. Saccon, Allancer D.C. Nunes, James L. Kirkland, Tamara Tchkonia, Augusto Schneider & Michal M. Masternak. (2020) Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice. Aging 12:3, pages 2711-2722.
Crossref
Wouter Tobias van Haaften, Tjasso Blokzijl, Hendrik Sijbrand Hofker, Peter Olinga, Gerard Dijkstra, Ruud A. Bank & Miriam Boersema. (2020) Intestinal stenosis in Crohn’s disease shows a generalized upregulation of genes involved in collagen metabolism and recognition that could serve as novel anti-fibrotic drug targets. Therapeutic Advances in Gastroenterology 13, pages 175628482095257.
Crossref
Ayse Karatug Kacar, Merve Yildirim, Sehnaz Bolkent & Fusun Oztay. (2019) The effects of atorvastatin on the kidney injury in mice with pulmonary fibrosis. Journal of Pharmacy and Pharmacology 71:8, pages 1301-1310.
Crossref
Asuncion Martinez-Anton, Delphine Gras, Arnaud Bourdin, Patrice Dubreuil & Pascal Chanez. (2019) KIT as a therapeutic target for non-oncological diseases. Pharmacology & Therapeutics 197, pages 11-37.
Crossref
Fusun Oztay, Ozgecan Kayalar & Merve Yildirim. 2019. Oxidative Stress in Lung Diseases. Oxidative Stress in Lung Diseases 325 353 .
Andrea Smargiassi, Giuliana Pasciuto, Emanuele Giovanni Conte, Mariarita Andreani, Roberta Marra & Luca Richeldi. 2019. Idiopathic Pulmonary Fibrosis. Idiopathic Pulmonary Fibrosis 325 364 .
Giuliana Pasciuto, Riccardo Inchingolo, Carola Condoluci, Daniele Magnini, Bruno Iovene & Luca Richeldi. (2018) Approved and Experimental Therapies for Idiopathic Pulmonary Fibrosis. Current Pulmonology Reports 7:4, pages 107-117.
Crossref
Ryota Kanemaru, Fumiyuki Takahashi, Motoyasu Kato, Yoichiro Mitsuishi, Ken Tajima, Hiroaki Ihara, Moulid Hidayat, Aditya Wirawan, Yoshika Koinuma, Daisuke Hayakawa, Shigehiro Yagishita, Ryo Ko, Tadashi Sato, Norihiro Harada, Yuzo Kodama, Fariz Nurwidya, Shinichi Sasaki, Shin-ichiro Niwa & Kazuhisa Takahashi. (2018) Dasatinib Suppresses TGFβ-Mediated Epithelial–Mesenchymal Transition in Alveolar Epithelial Cells and Inhibits Pulmonary Fibrosis. Lung 196:5, pages 531-541.
Crossref
Shijing Jia, Manisha Agarwal, Jibing Yang, Jeffrey C. Horowitz, Eric S. White & Kevin K. Kim. (2018) Discoidin Domain Receptor 2 Signaling Regulates Fibroblast Apoptosis through PDK1/Akt. American Journal of Respiratory Cell and Molecular Biology 59:3, pages 295-305.
Crossref
Jennifer M.S. Sucre, Gail H. Deutsch, Christopher S. Jetter, Namasivayam Ambalavanan, John T. Benjamin, Linda A. Gleaves, Bryan A. Millis, Lisa R. Young, Timothy S. Blackwell, Jonathan A. Kropski & Susan H. Guttentag. (2018) A Shared Pattern of β-Catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis. The American Journal of Pathology 188:4, pages 853-862.
Crossref
Fusun Oztay, Serap Sancar-Bas, Selda Gezginci-Oktayoglu, Merve Ercin & Sehnaz Bolkent. (2018) Exendin-4 partly ameliorates - hyperglycemia-mediated tissue damage in lungs of streptozotocin-induced diabetic mice. Peptides 99, pages 99-107.
Crossref
Daniele Magnini, Giuliano Montemurro, Bruno Iovene, Linda Tagliaboschi, Rafael Emanuele Gerardi, Erminia Lo Greco, Teresa Bruni, Alessio Fabbrizzi, Francesco Lombardi & Luca Richeldi. (2017) Idiopathic Pulmonary Fibrosis: Molecular Endotypes of Fibrosis Stratifying Existing and Emerging Therapies. Respiration 93:6, pages 379-395.
Crossref
Hu Zhao, Huan Bian, Xin Bu, Shuya Zhang, Pan Zhang, Jiangtian Yu, Xiaofeng Lai, Di Li, Chuchao Zhu, Libo Yao & Jin Su. (2016) Targeting of Discoidin Domain Receptor 2 (DDR2) Prevents Myofibroblast Activation and Neovessel Formation During Pulmonary Fibrosis. Molecular Therapy 24:10, pages 1734-1744.
Crossref
Xingqi Wang, Zijun Ouyang, Qian You, Shuai He, Qianqian Meng, Chunhui Hu, Xudong Wu, Yan Shen, Yang Sun, Xuefeng Wu & Qiang Xu. (2016) Obaculactone protects against bleomycin-induced pulmonary fibrosis in mice. Toxicology and Applied Pharmacology 303, pages 21-29.
Crossref
Dinesh Khanna, Jörg H.W. Distler, Peter Sandner & Oliver Distler. (2016) Emerging strategies for treatment of systemic sclerosis. Journal of Scleroderma and Related Disorders 1:2, pages 186-193.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.