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Original Article

Vitamin D3 and Calcipotriol Enhance the Secretion of Transforming Growth Factor-β1 and -β2 in Cultured Murine Keratinocytes

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Pages 153-163 | Received 03 Sep 1992, Accepted 09 Oct 1992, Published online: 11 Jul 2009

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Efstratios Vakirlis, Athanasios Kastanis & Demetrios Ioannides. (2008) Calcipotriol/betamethasone dipropionate in the treatment of psoriasis vulgaris. Therapeutics and Clinical Risk Management 4:1, pages 141-148.
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A Charakida, O Dadzie, F Teixeira, M Charakida, G Evangelou & AC Chu. (2006) Calcipotriol/betamethasone dipropionate for the treatment of psoriasis. Expert Opinion on Pharmacotherapy 7:5, pages 597-606.
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Articles from other publishers (41)

Marjolein van Driel, Alberto Muñoz & Johannes P.T.M. van Leeuwen. 2024. Feldman and Pike's Vitamin D. Feldman and Pike's Vitamin D 679 718 .
Erika Minowa, Yoshihito Kurashige, Syed Taufiqul Islam, Koki Yoshida, Sayaka Sakakibara, Yunosuke Okada, Yusuke Fujita, Dembereldorj Bolortsetseg, Yuji Murai, Yoshihiro Abiko & Masato Saitoh. (2021) Increased integrity of cell–cell junctions accompanied by increased expression of claudin 4 in keratinocytes stimulated with vitamin D3. Medical Molecular Morphology 54:4, pages 346-355.
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Marjolein van Driel, Johannes P.T.M. van Leeuwen, Alberto Muñoz & David Feldman. 2018. Vitamin D. Vitamin D 711 742 .
Isa Khaheshi, Saeed Keshavarz, Abbas Ali Imani Fooladi, Majid Ebrahimi, Samaneh Yazdani, Yunes Panahi, Majid Shohrati & Mohammad Reza Nourani. (2011) Loss of expression of TGF-βs and their receptors in chronic skin lesions induced by sulfur mustard as compared with chronic contact dermatitis patients. BMC Dermatology 11:1.
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Johannes P.T.M. van Leeuwen, Marjolein van Driel, David Feldman & Alberto Muñoz. 2011. Vitamin D. Vitamin D 1591 1624 .
Arnaud Teichert & Daniel D. Bikle. 2011. Signaling Pathways in Squamous Cancer. Signaling Pathways in Squamous Cancer 283 303 .
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Daniel D. Bikle, Yuko Oda & Zhongian Xie. (2005) Vitamin D and skin cancer: A problem in gene regulation. The Journal of Steroid Biochemistry and Molecular Biology 97:1-2, pages 83-91.
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JOHANNES P.T.M. VAN LEEUWEN & HUIBERT A.P. POLS. 2005. Vitamin D. Vitamin D 1571 1597 .
Daniel D. Bikle. (2004) Vitamin D and Skin Cancer. The Journal of Nutrition 134:12, pages 3472S-3478S.
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Justin Annes, Melinda Vassallo, John S Munger & Daniel B Rifkin. (2004) A genetic screen to identify latent transforming growth factor β activators. Analytical Biochemistry 327:1, pages 45-54.
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P.C.M. van de Kerkhof & P.E.J. van Erp. 2003. Textbook of Psoriasis. Textbook of Psoriasis 83 109 .
Christian Lefebvre d'Hellencourt, Claudia N. Montero-Menei, Rozenn Bernard & Dominique Couez. (2003) Vitamin D3 inhibits proinflammatory cytokines and nitric oxide production by the EOC13 microglial cell line. Journal of Neuroscience Research 71:4, pages 575-582.
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Elin Albrechtsson, Tord Jonsson, Sebastian Möller, Mattias Höglund, Bodil Ohlsson & Jan Axelson. (2003) Vitamin D receptor is expressed in pancreatic cancer cells and a vitamin D3 analogue decreases cell number. Pancreatology 3:1, pages 41-46.
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Alper Gurlek, Mark R. Pittelkow & Rajiv Kumar. (2002) Modulation of Growth Factor/Cytokine Synthesis and Signaling by 1α,25-Dihydroxyvitamin D3: Implications in Cell Growth and Differentiation. Endocrine Reviews 23:6, pages 763-786.
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Carlos L. Arteaga. (2002) The tumor microenvironment: a potential arbitrator of the tumor suppressive and promoting actions of TGFβ. Differentiation 70:9-10, pages 574-582.
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David Nagel & Rajiv Kumar. (2002) 1α,25-Dihydroxyvitamin D3 Increases TGF β1 Binding to Human Osteoblasts. Biochemical and Biophysical Research Communications 290:5, pages 1558-1563.
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Kerry L. Burnstein. 2002. Steroid Hormones and Cell Cycle Regulation. Steroid Hormones and Cell Cycle Regulation 173 190 .
Christian Beck, Hans Schreiber & Donald A. Rowley. (2001) Role of TGF-? in immune-evasion of cancer. Microscopy Research and Technique 52:4, pages 387-395.
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Katri Koli, Juha Saharinen, Marko Hyyti�inen, Carita Penttinen & Jorma Keski-Oja. (2001) Latency, activation, and binding proteins of TGF-?. Microscopy Research and Technique 52:4, pages 354-362.
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N. Oyama, K. Iwatsuki, M. Satoh, H. Akiba & F. Kaneko. (2001) Dermal fibroblasts are one of the therapeutic targets for topical application of 1α,25‐dihydroxyvitamin D 3 : the possible involvement of transforming growth factor‐β induction . British Journal of Dermatology 143:6, pages 1140-1148.
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T. Leivo, U. Kiistala, M. Vesterinen, K. Owaribe, R.E. Burgeson, I. Virtanen & A. Oikarinen. (2000) Re-epithelialization rate and protein expression in the suction-induced wound model: comparison between intact blisters, open wounds and calcipotriol-pretreated open wounds. British Journal of Dermatology 142:5, pages 991-1002.
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Juha Saharinen, Marko Hyytiäinen, Jussi Taipale & Jorma Keski-Oja. (1999) Latent transforming growth factor-β binding proteins (LTBPs)—structural extracellular matrix proteins for targeting TGF-β action. Cytokine & Growth Factor Reviews 10:2, pages 99-117.
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Katri M. Koli & Carlos L. Arteaga. 1999. Breast Cancer. Breast Cancer 95 119 .
H�l�ne Defacque, David Piquemal, Annie Basset, Jacques Marti & Th�r�se Commes. (1999) Transforming growth factor-?1 is an autocrine mediator of U937 cell growth arrest and differentiation induced by vitamin D3 and retinoids. Journal of Cellular Physiology 178:1, pages 109-119.
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Yuji Yamaguchi, Satoshi Itami, Kenju Nishida & Yumi Ando. (1998) Taurin-conjugated ursodeoxycholic acid has a reversible inhibitory effect on human keratinocyte growth. Journal of Dermatological Science 18:1, pages 35-42.
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L. Verlinden, A. Verstuyf, R. Convents, S. Marcelis, M. Van Camp & R. Bouillon. (1998) Action of 1,25(OH)2D3 on the cell cycle genes, cyclin D1, p21 and p27 in MCF-7 cells. Molecular and Cellular Endocrinology 142:1-2, pages 57-65.
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Jussi Taipale, Juha Saharinen & Jorma Keski-Oja. 1998. 87 134 .
Yanhong Wu, James D. Haugen, Alan R. Zinsmeister & Rajiv Kumar. (1997) 1α,25-Dihydroxyvitamin D3Increases Transforming Growth Factor and Transforming Growth Factor Receptor Type I and II Synthesis in Human Bone Cells. Biochemical and Biophysical Research Communications 239:3, pages 734-739.
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John S. Munger, John G. Harpel, Pierre-Emmanuel Gleizes, Roberta Mazzieri, Irene Nunes & Daniel B. Rifkin. (1997) Latent transforming growth factor-β: Structural features and mechanisms of activation. Kidney International 51:5, pages 1376-1382.
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Robert Gniadecki. (2009) Effects of 1,25‐dihydroxyvitamin D 3 and its 20‐epi analogues (MC 1288, MC 1301, KH 1060), on clonal keratinocyte growth: evidence for differentiation of keratinocyte stem cells and analysis of the modulatory effects of cytokines . British Journal of Pharmacology 120:6, pages 1119-1127.
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Noriaki Toyota, Hiroyuki Sakai, Hidetoshi Takahashi, Yoshio Hashimoto & Hajime Iizuka. (1996) Inhibitory effect of 1α,25-dihydroxyvitamin D3 on mast cell proliferation and A23187-induced histamine release, also accompanied by a decreased c-kit receptor. Archives of Dermatological Research 288:11, pages 709-715.
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Andrew P. Lea & Karen L. Goa. (2012) Calcipotriol. Clinical Immunotherapeutics 5:3, pages 230-248.
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Katri Koli & Jorma Keski-Oja. 1996. 63 94 .
David Danielpour. (1996) Induction of transforming growth factor-β autocrine activity by all-trans-retinoic acid and 1α,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells. Journal of Cellular Physiology 166:1, pages 231-239.
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Yoshio Hashimoto, Masato Tsutsui, Shinobu Matsuo, Susumu Iizuka & Hajime Iizuka. (1995) Topical tacalcitol (1,24-(R)-dihydroxyvitamin D3) induces a transient increase in thymidine incorporation and calmodulin content in pig epidermis following tape stripping in vivo. Journal of Dermatological Science 10:3, pages 196-202.
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R. GNIADECKI, M. GNIADECKA & J. SERUP. (2010) The effects of KH 1060, a potent 20-epi analogue of the vitamin D3 hormone, on hairless mouse skin in vivo. British Journal of Dermatology 132:6, pages 841-852.
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FredVVan Ruissen, Peter C.M. Van De Kerkhof & Joost Schalkwijk. (1995) Signal transduction pathways in epidermal proliferation and cutaneous inflammation. Clinics in Dermatology 13:2, pages 161-190.
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Errol Prens, Reno Debets & Joost Hegmans. (1995) T lymphocytes in psoriasis. Clinics in Dermatology 13:2, pages 115-129.
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Robert Gniadecki & Jørgen Serup. (1995) Stimulation of epidermal proliferation in mice with 1α,25-dihydroxyvitamin D3 and receptor-active 20-epi analogues of 1α,25-dihydroxyvitamin D3. Biochemical Pharmacology 49:5, pages 621-624.
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Katri Koli & Jorma Keski-Oja. (1993) Vitamin D3 and Calcipotriol Decrease Extracellular Plasminogen Activator Activity in Cultured Keratinocytes. Journal of Investigative Dermatology 101:5, pages 706-712.
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