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Research Article

Nanoethosomal formulation for skin targeting of amphotericin B: an in vitro and in vivo assessment

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Pages 294-307 | Received 04 Aug 2014, Accepted 03 Dec 2014, Published online: 30 Dec 2014

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Tushit Sharma, Shubham Thakur, Manjot Kaur, Amrinder Singh & Subheet Kumar Jain. (2023) Novel Hyaluronic Acid ethosomes based gel formulation for topical use with reduced toxicity, better skin permeation, deposition, and improved pharmacodynamics. Journal of Liposome Research 33:2, pages 129-143.
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Manjot Kaur, Kanwardeep Singh & Subheet Kumar Jain. (2020) Luliconazole vesicular based gel formulations for its enhanced topical delivery. Journal of Liposome Research 30:4, pages 388-406.
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Subheet Kumar Jain, Manreet Kaur, Pankaj Kalyani, Anshula Mehra, Navjot Kaur & Neha Panchal. (2019) Microsponges enriched gel for enhanced topical delivery of 5-fluorouracil. Journal of Microencapsulation 36:7, pages 677-691.
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Tian Fu, Jinglin Yi, Songyi Lv & Bing Zhang. (2017) Ocular amphotericin B delivery by chitosan-modified nanostructured lipid carriers for fungal keratitis-targeted therapy. Journal of Liposome Research 27:3, pages 228-233.
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Aishwarya Agrawal, Aalind Joshi & Sankha Bhattacharya. (2024) Recent Excavation of Nanoethosomes in Current Drug Delivery. Current Drug Delivery 21:2, pages 168-183.
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Manjot Kaur, Riya Shivgotra, Shubham Thakur, Rasdeep Kour, Manpreet Singh, Navid Reza Shahtaghi, Satwinderjeet Kaur & Subheet Kumar Jain. (2023) A novel nanoemulgel formulation of Luliconazole with augmented antifungal efficacy: In-vitro, in-silico, ex-vivo, and in-vivo studies. Journal of Drug Delivery Science and Technology 89, pages 105102.
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Manishi Mahajan, Manjot Kaur, Shubham Thakur, Amrinder Singh, Navid Reza Shahtaghi, Riya Shivgotra, Nitish Bhardwaj, Shagun Saini & Subheet Kumar Jain. (2022) Solid Lipid Nanoparticles as Carrier to Increase Local Bioavailability of Acitretin After Topical Administration in Psoriasis Treatment. Journal of Pharmaceutical Innovation 18:1, pages 220-237.
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Hassan Raza, Shefaat Ullah Shah, Zakir Ali, Atif Ullah Khan, Irfa Basharat Rajput, Arshad Farid, Mohammed Al Mohaini, Abdulkhaliq J. Alsalman, Maitham A. Al Hawaj, Saima Mahmood, Abid Hussain & Kifayat Ullah Shah. (2022) In Vitro and Ex Vivo Evaluation of Fluocinolone Acetonide–Acitretin-Coloaded Nanostructured Lipid Carriers for Topical Treatment of Psoriasis. Gels 8:11, pages 746.
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Shanta Mahajan, Kirandeep Kaur, Navdeep Saini, Tajeshwar Kumar Chaudhary, Lovedeep Nim & Neena Bedi. (2022) Development and Evaluation of Topical Nanoemulgel Formulation of Tazarotene for Effective Treatment of Excision Wounds. Current Nanomedicine 12:2, pages 137-149.
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Mogana Rajagopal, Alok K. Paul, Ming-Tatt Lee, Anabelle Rose Joykin, Choo-Shiuan Por, Tooba Mahboob, Cristina C. Salibay, Mario S. Torres, Maria Melanie M. Guiang, Mohammed Rahmatullah, Rownak Jahan, Khoshnur Jannat, Polrat Wilairatana, Maria de Lourdes Pereira, Chooi Ling Lim & Veeranoot Nissapatorn. (2022) Phytochemicals and Nano-Phytopharmaceuticals Use in Skin, Urogenital and Locomotor Disorders: Are We There?. Plants 11:9, pages 1265.
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Bhaskar Kurangi, Sunil Jalalpure & Satveer Jagwani. (2021) Formulation and Evaluation of Resveratrol Loaded Cubosomal Nanoformulation for Topical Delivery. Current Drug Delivery 18:5, pages 607-619.
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Shweta Nene, Saurabh Shah, Nagarjun Rangaraj, Neelesh Kumar Mehra, Pankaj Kumar Singh & Saurabh Srivastava. (2021) Lipid based nanocarriers: A novel paradigm for topical antifungal therapy. Journal of Drug Delivery Science and Technology 62, pages 102397.
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Manuela Carvalheiro, Jennifer Vieira, Catarina Faria-Silva, Joana Marto & Sandra Simões. (2021) Amphotericin B-loaded deformable lipid vesicles for topical treatment of cutaneous leishmaniasis skin lesions. Drug Delivery and Translational Research 11:2, pages 717-728.
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Navjot Kaur, Manjot Kaur, Manishi Mahajan & Subheet Kumar Jain. (2020) Development, characterization and evaluation of nanocarrier based formulations of antipsoriatic drug “acitretin” for skin targeting. Journal of Drug Delivery Science and Technology 60, pages 102010.
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Anjali Mishra, Mehdiya Bano, Amol Chhatrapati Bisen, Sarvesh Verma, Sachin Nashik Sanap, Raj Kishor, P.K. Shukla & Rabi Sankar Bhatta. (2020) Topical corneal targeted sustained release amphotericin B liposomal formulation for the treatment of fungal keratitis and its PK-PD evaluation. Journal of Drug Delivery Science and Technology 60, pages 101944.
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Sara R. Botros, Amal K. Hussein & Heba F. Mansour. (2020) A Novel Nanoemulsion Intermediate Gel as a Promising Approach for Delivery of Itraconazole: Design, In Vitro and Ex Vivo Appraisal. AAPS PharmSciTech 21:7.
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Faustino & Pinheiro. (2020) Lipid Systems for the Delivery of Amphotericin B in Antifungal Therapy. Pharmaceutics 12:1, pages 29.
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Kanika Thakur, Gajanand Sharma, Bhupindar Singh & Om Prakash Katare. (2019) Topical Drug Delivery of Anti-infectives Employing Lipid-Based Nanocarriers: Dermatokinetics as an Important Tool. Current Pharmaceutical Design 24:43, pages 5108-5128.
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Feilong Zhou, Hongmei Xu, Zhimei Song, Li Zhu, Sijia Feng & Runliang Feng. (2019) α-Linolenic acid-modified pluronic 127-CS copolymeric micelles for the skin targeted delivery of amphotericin B. New Journal of Chemistry 43:1, pages 444-453.
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Lakhvir Kaur, Kanwaldeep Singh, Surinder Paul, Sukhprit Singh, Shashank Singh & Subheet Kumar Jain. (2018) A Mechanistic Study to Determine the Structural Similarities Between Artificial Membrane Strat-M™ and Biological Membranes and Its Application to Carry Out Skin Permeation Study of Amphotericin B Nanoformulations. AAPS PharmSciTech 19:4, pages 1606-1624.
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Lilian Sosa, Beatriz Clares, Helen L. Alvarado, Nuria Bozal, Oscar Domenech & Ana C. Calpena. (2017) Amphotericin B releasing topical nanoemulsion for the treatment of candidiasis and aspergillosis. Nanomedicine: Nanotechnology, Biology and Medicine 13:7, pages 2303-2312.
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MS Roberts, Y Mohammed, MN Pastore, S Namjoshi, S Yousef, A Alinaghi, IN Haridass, E Abd, VR Leite-Silva, HAE Benson & JE Grice. (2017) Topical and cutaneous delivery using nanosystems. Journal of Controlled Release 247, pages 86-105.
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Swati Pund & Amita Joshi. 2017. Nano- and Microscale Drug Delivery Systems. Nano- and Microscale Drug Delivery Systems 439 480 .
Pio Maria Furneri, Giulio P. Petronio, Virginia Fuochi, Sarha Cupri & Rosario Pignatello. 2017. Nanostructures for Drug Delivery. Nanostructures for Drug Delivery 697 748 .
N. Škalko-Basnet & Ž. Vanić. 2017. Functionalized Nanomaterials for the Management of Microbial Infection. Functionalized Nanomaterials for the Management of Microbial Infection 111 152 .

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