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Journal of Liposome Research Volume 2, 1992 - Issue 1
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Research Article

Preparation and Characterization of Liposomal Doxorubicin for Human Use

Shimon Amselem Departments of Membrane Biochemistry, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
,
Rivka Cohen Departments of Membrane Biochemistry, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
,
Shula Druckmann Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
,
Alberto Gabizon Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
,
Dorit Goren Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
,
Robert M. Abra Liposome Technology Inc., Menlo Park, California, USA
,
Anthony Huang Liposome Technology Inc., Menlo Park, California, USA
,
Roger New Royal Liverpool Hospital, Liverpool, United Kingdom
&
Yechezkel Barenholz Departments of Membrane Biochemistry, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
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Pages 93-123 | Published online: 28 Sep 2008

Citations (17)

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Elijah M. Bolotin, Rivka Cohen, Liliana K. Bar, Noam Emanuel, Sami Ninio, Yechezkel Barenholz & Danilo D. Lasic. (1994) Ammonium Sulfate Gradients for Efficient and Stable Remote Loading of Amphipathic Weak Bases into Liposomes and Ligandoliposomes.. Journal of Liposome Research 4:1, pages 455-479.
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D. Engelhard, A. Eldor, I. Polacheck, I. Hardan, D. Ben-yehuda, S. Amselem, I. F. Salkin, G. Lopez-berestein, T. Sacks, E. A. Rachmilewitz & Y. Barenholz. (1993) Disseminated Visceral Fusariosis Treated with Amphotericin B-Phospholipid Complex. Leukemia & Lymphoma 9:4-5, pages 385-392.
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Articles from other publishers (15)

Vedagopuram Sreekanth, Nihal Medatwal, Sanjay Pal, Sandeep Kumar, Sagar Sengupta & Avinash Bajaj. (2017) Molecular Self-Assembly of Bile Acid-Phospholipids Controls the Delivery of Doxorubicin and Mice Survivability. Molecular Pharmaceutics 14:8, pages 2649-2659.
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Zhong-Kai Cui, Katarina Edwards, Alejandro Nieto Orellana, Guillaume Bastiat, Jean-Pierre Benoit & Michel Lafleur. (2014) Impact of interfacial cholesterol-anchored polyethylene glycol on sterol-rich non-phospholipid liposomes. Journal of Colloid and Interface Science 428, pages 111-120.
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Manish Singh, Somanath Kundu, Amarendar Reddy M, Vedagopuram Sreekanth, Rajender K. Motiani, Sagar Sengupta, Aasheesh Srivastava & Avinash Bajaj. (2014) Injectable small molecule hydrogel as a potential nanocarrier for localized and sustained in vivo delivery of doxorubicin. Nanoscale 6:21, pages 12849-12855.
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Thong Cao, Michael Mitchell, Jane Liesveld & Michael King. (2013) Stem Cell Enrichment with Selectin Receptors: Mimicking the pH Environment of Trauma. Sensors 13:9, pages 12516-12526.
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Michael J. Mitchell, Christina S. Chen, Varun Ponmudi, Andrew D. Hughes & Michael R. King. (2012) E-selectin liposomal and nanotube-targeted delivery of doxorubicin to circulating tumor cells. Journal of Controlled Release 160:3, pages 609-617.
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Michael J. Mitchell, Carlos A. Castellanos & Michael R. King. (2012) Nanostructured Surfaces to Target and Kill Circulating Tumor Cells While Repelling Leukocytes. Journal of Nanomaterials 2012, pages 1-10.
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Yechezkel Barenholz. 2006. Liposome Technology, Volume II. Liposome Technology, Volume II 1 25 .
Ayelet M Samuni, Alexander Lipman & Yechezkel Barenholz. (2000) Damage to liposomal lipids: protection by antioxidants and cholesterol-mediated dehydration. Chemistry and Physics of Lipids 105:2, pages 121-134.
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Liliana K. Bar, Yechezkel Barenholz & Thomas E. Thompson. (1997) Effect of Sphingomyelin Composition on the Phase Structure of Phosphatidylcholine−Sphingomyelin Bilayers. Biochemistry 36:9, pages 2507-2516.
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Sriram Vemuri & C.T Rhodes. (1995) Preparation and characterization of liposomes as therapeutic delivery systems: a review. Pharmaceutica Acta Helvetiae 70:2, pages 95-111.
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Shimon Amselem, Rivka Cohen & Yechezkel Barenholz. (1993) In vitro tests to predict in vivo performance of liposomal dosage forms. Chemistry and Physics of Lipids 64:1-3, pages 219-237.
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Vered Borenstain & Yechezkel Barenholz. (1993) Characterization of liposomes and other lipid assemblies by multiprobe fluorescence polarization. Chemistry and Physics of Lipids 64:1-3, pages 117-127.
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Raphael Gorodetsky, Shimon Amselem & Yechezkel Barenholz. (1993) Trace element analysis of liposomal formulations by diagnostic X-ray fluorescence spectrometry (DXS). Chemistry and Physics of Lipids 64:1-3, pages 31-34.
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Gilad Haran, Rivka Cohen, Liliana K Bar & Yechezkel Barenholz. (1993) Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochimica et Biophysica Acta (BBA) - Biomembranes 1151:2, pages 201-215.
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Yechezkel Barenholz, Shimon Amselem, Dorit Goren, Rivka Cohen, Dan Gelvan, Amram Samuni, Elisabeth B. Golden & Alberto Gabizon. (2006) Stability of liposomal doxorubicin formulations: Problems and prospects. Medicinal Research Reviews 13:4, pages 449-491.
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