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Journal of Liposome Research Volume 5, 1995 - Issue 1
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Research Article

Preclinical Properties of N4-Hexadecyl- and N4- Octadecyl-1-β-D-Arabinofuranosylcytosine in Liposomal Preparations

R. A. Schwendener Department of Internal Medicine, Division of Oncology, University Hospital, CH-8091, Zürich
,
D. H. Horber Department of Internal Medicine, Division of Oncology, University Hospital, CH-8091, Zürich
,
C. Ottiger Department of Internal Medicine, Division of Oncology, University Hospital, CH-8091, Zürich
&
H. Schott Institute of Organic Chemistry, University of Tübingen, D-72076, Tübingen
Pages 27-47 | Published online: 28 Sep 2008

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GodefridusJ. Peters, AukeD. Adema, IreneV. Bijnsdorp & MaritL. Sandvold. (2011) Lipophilic Prodrugs and Formulations of Conventional (Deoxy)Nucleoside and Fluoropyrimidine Analogs in Cancer. Nucleosides, Nucleotides & Nucleic Acids 30:12, pages 1168-1180.
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Articles from other publishers (9)

Reto Schwendener & Herbert Schott. 2006. Liposome Technology, Volume II. Liposome Technology, Volume II 51 62 .
Takeshi Terada, Mieko Iwai, Shigeru Kawakami, Fumiyoshi Yamashita & Mitsuru Hashida. (2006) Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. Journal of Controlled Release 111:3, pages 333-342.
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Reto Schwendener & Herbert Schott. 2005. Liposomes. Liposomes 58 70 .
Akinobu Hamada, Takeo Kawaguchi & Masahiro Nakano. (2002) Clinical Pharmacokinetics of Cytarabine Formulations. Clinical Pharmacokinetics 41:10, pages 705-718.
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R.A. Schwendener, K. Friedl, H. Depenbrock, H. Schott & A.-R. Hanauske. (2001) In vitro activity of liposomal N4octadecyl-1-β-D-arabinofurano-sylcytosine (NOAC), a new lipophilic derivative of 1-β-D-arabino-furanocylcytosine on biopsized clonogenic human tumor cells and hematopoietic precursor cells. Investigational New Drugs 19:3, pages 203-210.
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R.M.C. Cattaneo-Pangrazzi, H. Schott & R.A. Schwendener. (2000) The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145. The Prostate 45:1, pages 8-18.
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Monica Gulati, Manish Grover, Saranjit Singh & Mandip Singh. (1998) Lipophilic drug derivatives in liposomes. International Journal of Pharmaceutics 165:2, pages 129-168.
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R. A. Schwendener & H. Schott. (1996) Lipophilic 1-?-d-arabinofuranosyl cytosine derivatives in liposomal formulations for oral and parenteral antileukemic therapy in the murine L1210 leukemia model. Journal of Cancer Research and Clinical Oncology 122:12, pages 723-726.
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R. A. Schwendener, D. H. Horber, B. Odermatt & H. Schott. (1996) Oral antitumour activity in murine L1210 leukaemia and pharmacological properties of liposome formulations ofN 4-alkyl derivatives of 1-?-d-arabinofuranosylcytosine. Journal of Cancer Research and Clinical Oncology 122:2, pages 102-108.
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