474
Views
49
CrossRef citations to date
0
Altmetric
Original Article

An Update on the Genetics of HLA B27-associated Acute Anterior Uveitis

, MD & , PhD
Pages 108-114 | Received 26 Jan 2011, Accepted 27 Jan 2011, Published online: 23 Mar 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Jordan T Jones, Jacqueline Kitchen & Nasreen Talib. (2022) Down Syndrome-Associated Arthritis (DA): Diagnostic and Management Challenges. Pediatric Health, Medicine and Therapeutics 13, pages 53-62.
Read now
Denis Wakefield, William Yates, Shahriar Amjadi & Peter McCluskey. (2016) HLA-B27 Anterior Uveitis: Immunology and Immunopathology. Ocular Immunology and Inflammation 24:4, pages 450-459.
Read now

Articles from other publishers (47)

Jordan Dean, Sloane McTavish, Yilin Feng, Sandra Hoyek & Nimesh A. Patel. (2023) Persistent Inflammation Associated With HLA-B27 After Pars Plana Vitrectomy With Scleral Buckle Placement. Journal of VitreoRetinal Diseases 7:6, pages 557-561.
Crossref
Danielle dos Reis Annunciato, Thauana Luiza Oliveira, Vanessa Oliveira Magalhães & Marcelo de Medeiros Pinheiro. (2023) Extra-musculoskeletal manifestations driving the therapeutic decision-making in patients with Spondyloarthritis: a 12-month follow-up prospective cohort study. Advances in Rheumatology 63:1.
Crossref
Cristiana Sieiro Santos, Isabel Sendino-Tenorio, Carolina Álvarez Castro, Clara Moriano Morales, Miguel Cordero Coma & Elvira Díez Álvarez. (2023) Factors Associated With Adverse Outcomes in Uveitis Related to Spondyloarthritis. JCR: Journal of Clinical Rheumatology 29:3, pages 132-138.
Crossref
Skender Topi, Lucrezia Bottalico, Ioannis Alexandros Charitos, Marica Colella, Marina Di Domenico, Raffaele Palmirotta & Luigi Santacroce. (2022) Biomolecular Mechanisms of Autoimmune Diseases and Their Relationship with the Resident Microbiota: Friend or Foe?. Pathophysiology 29:3, pages 507-536.
Crossref
Yi-Chiao Bai, Chin-Hsiu Liu, Pui-Ying Leong, Kuo-Lung Lai, Hsin-Hua Chen & James Cheng-Chung Wei. (2022) The Risk of Major Adverse Cardiovascular Events in Ankylosing Spondylitis Patients With a History of Acute Anterior Uveitis: A Nationwide, Population Based Cohort Study. Frontiers in Medicine 9.
Crossref
Dominic King, Joht Singh Chandan, Tom Thomas, Alastair K Denniston, Tasanee Braithwaite, Krishnarajah Niranthrankumar, Raoul Reulen, Nicola Adderley & Nigel J Trudgill. (2022) Risk of a subsequent diagnosis of inflammatory bowel disease in subjects with ophthalmic disorders associated with inflammatory bowel disease: a retrospective cohort analysis of UK primary care data. BMJ Open 12:5, pages e052833.
Crossref
Yi-Fen Lai, Ting-Yi Lin, Wu-Chien Chien, Chien-An Sun, Chi-Hsiang Chung, Yi-Hao Chen, Jiann-Torng Chen & Ching-Long Chen. (2022) Uveitis as a Risk Factor for Developing Acute Myocardial Infarction in Ankylosing Spondylitis: A National Population-Based Longitudinal Cohort Study. Frontiers in Immunology 12.
Crossref
Yoonkyeom Shin, Ji-Man Kang, Junwon Lee, Christopher Seungkyu Lee, Sung Chul Lee & Jong Gyun Ahn. (2021) Epidemiology of pediatric uveitis and associated systemic diseases. Pediatric Rheumatology 19:1.
Crossref
Jonathan Regenold, Hashem Ghoraba, Amir Akhavanrezayat, Wataru Matsumiya, Azadeh Mobasserian, Irmak Karaca, Moosa Zaidi, Brandon Pham & Quan Dong Nguyen. (2021) Unilateral acute anterior uveitis with macular edema following the use of sildenafil citrate in a patient with HLA-B27 positivity. American Journal of Ophthalmology Case Reports 24, pages 101228.
Crossref
Alfred Yu Ting Chia, Gladys Wei Xin Ang, Anita Sook Yee Chan, Webber Chan, Timothy Kit Yeong Chong & Ying Ying Leung. (2021) Managing Psoriatic Arthritis With Inflammatory Bowel Disease and/or Uveitis. Frontiers in Medicine 8.
Crossref
Nazife Şule Yaşar Bilge, Umut Kalyoncu, Pamir Atagündüz, Ediz Dalkılıç, Yavuz Pehlivan, Orhan Küçükşahin, Cemal Bes, Servet Akar, Muhammet Cinar, Hakan Emmungil, Duygu Ersözlü, Aşkın Ateş, Rıdvan Mercan, Gezmiş Kimyon, Süleyman Serdar Koca, Emel Gonullu, Veli Yazisiz, Emre Tekgöz, Nilüfer Alpay-Kanitez, Abdulsamet Erden, Sedat Kiraz, Belkıs Nihan Coskun, Burcu Yağız, Ufuk İlgen, Ömer Karadağ, Levent Kilic, İhsan Ertenli & Timuçin Kasifoglu. (2021) Uveitis-related Factors in Patients With Spondyloarthritis: TReasure Real-Life Results. American Journal of Ophthalmology 228, pages 58-64.
Crossref
Qiuyun Xu, Jie Zhang, Tingyu Qin, Jingyin Bao, Hongtao Dong, Xiaorong Zhou, Shengping Hou & Liming Mao. (2021) The role of the inflammasomes in the pathogenesis of uveitis. Experimental Eye Research 208, pages 108618.
Crossref
Denis Wakefield, Daniel Clarke & Peter McCluskey. (2021) Recent Developments in HLA B27 Anterior Uveitis. Frontiers in Immunology 11.
Crossref
Elsa How Shing Koy, Pierre Labauge, Athan Baillet, Clément Prati, Hubert Marotte & Yves-Marie Pers. (2021) Immunomodulation with IL-17 and TNF-α in spondyloarthritis: focus on the eye and the central nervous system. Therapeutic Advances in Musculoskeletal Disease 13, pages 1759720X2110258.
Crossref
Judith Rademacher, Uwe Pleyer & Sibylle Winterhalter. 2021. Entzündliche Augenerkrankungen. Entzündliche Augenerkrankungen 503 517 .
Farhad Babaie, Ramin Hosseinzadeh, Mehrdad Ebrazeh, Narges Seyfizadeh, Saeed Aslani, Soraya Salimi, Maryam Hemmatzadeh, Gholamreza Azizi, Farhad Jadidi-Niaragh & Hamed Mohammadi. (2020) The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective. Molecular Immunology 121, pages 7-19.
Crossref
Karin Bengtsson, Eva Klingberg, Anna Deminger, Hanna Wallberg, Lennart T H Jacobsson, Lennart Bergfeldt & Helena Forsblad-d’Elia. (2019) Cardiac conduction disturbances in patients with ankylosing spondylitis: results from a 5-year follow-up cohort study. RMD Open 5:2, pages e001053.
Crossref
Yufeng Qian, Bingqian Chen, Xiaowen Sheng & Yuqin Peng. (2019) The LMP2 CfoI polymorphism is associated with ankylosing spondylitis (AS) risk but not with acute anterior uveitis (AAU). Medicine 98:45, pages e17804.
Crossref
Ashvini Reddy, Fauziyya Muhammad & Darren J. Lee. 2019. Advances in the Diagnosis and Management of Uveitis. Advances in the Diagnosis and Management of Uveitis.
Resham Pattani. (2018) Paediatric eye care Part 2 – Uveitis. Optician 2018:1, pages 6860-1.
Crossref
B R Brown, E J Lee, P E Snow, E E Vance, Y Iwakura, N Ohno, N Miura, X Lin, G D Brown, C A Wells, J R Smith, R R Caspi & H L Rosenzweig. (2017) Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism. Clinical and Experimental Immunology 190:3, pages 293-303.
Crossref
Margo S. Clarke. (2017) Why do Diseases Start One Sided? Clues From HLA-B27 Acute Anterior Uveitis. EMJ Rheumatology, pages 76-82.
Crossref
Adrian Cortes, Calliope A Dendrou, Allan Motyer, Luke Jostins, Damjan Vukcevic, Alexander Dilthey, Peter Donnelly, Stephen Leslie, Lars Fugger & Gil McVean. (2017) Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank. Nature Genetics 49:9, pages 1311-1318.
Crossref
Ming Ming Yang, Jun Wang, Li Dong, De Ju Kong, Yan Teng, Ping Liu, Jiao Jie Fan & Xu Hui Yu. (2017) Lack of association of C3 gene with uveitis: additional insights into the genetic profile of uveitis regarding complement pathway genes. Scientific Reports 7:1.
Crossref
Andreea S Postole, Alexandra B Knoll, Gerd U Auffarth & Friederike Mackensen. (2016) In vivo confocal microscopy of inflammatory cells in the corneal subbasal nerve plexus in patients with different subtypes of anterior uveitis. British Journal of Ophthalmology 100:11, pages 1551-1556.
Crossref
José A. López de Castro, Carlos Alvarez-Navarro, Ariadna Brito, Pablo Guasp, Adrian Martín-Esteban & Alejandro Sanz-Bravo. (2016) Molecular and pathogenic effects of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in MHC-I-associated inflammatory disorders: Towards a unifying view. Molecular Immunology 77, pages 193-204.
Crossref
Ellen J. Lee, Brieanna R. Brown, Emily E. Vance, Paige E. Snow, Phyllis B. Silver, David Heinrichs, Xin Lin, Yoichiro Iwakura, Christine A. Wells, Rachel R. Caspi & Holly L. Rosenzweig. (2016) Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye. The Journal of Immunology 196:7, pages 3148-3158.
Crossref
Ross E. Petty & James T. Rosenbaum. 2016. Textbook of Pediatric Rheumatology. Textbook of Pediatric Rheumatology 274 284.e3 .
Ulrich Weber, Walter P. Maksymowych, Stanley M. Chan, Kaspar Rufibach, Susanne J. Pedersen, Zheng Zhao, Veronika Zubler, Mikkel ?stergaard & Robert GW Lambert. (2015) Does evaluation of the ligamentous compartment enhance diagnostic utility of sacroiliac joint MRI in axial spondyloarthritis?. Arthritis Research & Therapy 17:1.
Crossref
Ellen J. Lee, Emily E. Vance, Brieanna R. Brown, Paige S. Snow, Jenna S. Clowers, Shimon Sakaguchi & Holly L. Rosenzweig. (2015) Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice. Arthritis Research & Therapy 17:1.
Crossref
Ulrich Weber, Mikkel ?stergaard, Robert G W Lambert, Susanne J Pedersen, Stanley M Chan, Veronika Zubler, Kaspar Rufibach, Zheng Zhao & Walter P Maksymowych. (2015) Candidate lesion-based criteria for defining a positive sacroiliac joint MRI in two cohorts of patients with axial spondyloarthritis. Annals of the Rheumatic Diseases 74:11, pages 1976-1982.
Crossref
Muhammad A. Khan, Muhammad Haroon & James T. Rosenbaum. (2015) Acute Anterior Uveitis and Spondyloarthritis: More Than Meets the Eye. Current Rheumatology Reports 17:9.
Crossref
Ulrich Weber, Veronika Zubler, Zheng Zhao, Robert GW Lambert, Stanley M Chan, Susanne J Pedersen, Mikkel Østergaard, Kaspar Rufibach & Walter P Maksymowych. (2015) Does spinal MRI add incremental diagnostic value to MRI of the sacroiliac joints alone in patients with non-radiographic axial spondyloarthritis?. Annals of the Rheumatic Diseases 74:6, pages 985-992.
Crossref
Ulrich Weber, Zheng Zhao, Kaspar Rufibach, Veronika Zubler, Robert G. W. Lambert, Stanley M. Chan, Mikkel ?stergaard, Susanne J. Pedersen & Walter P. Maksymowych. (2015) Diagnostic Utility of Candidate Definitions for Demonstrating Axial Spondyloarthritis on Magnetic Resonance Imaging of the Spine. Arthritis & Rheumatology 67:4, pages 924-933.
Crossref
Hatem Zeghidi, Phuc Le Hoang & Bahram Bodaghi. (2015) Œil de la spondyloarthrite. Revue du Rhumatisme Monographies 82:1, pages 17-21.
Crossref
Philip C. Robinson, Theodora A. M. Claushuis, Adrian Cortes, Tammy M. Martin, David M. Evans, Paul Leo, Pamela Mukhopadhyay, Linda A. Bradbury, Katie Cremin, Jessica Harris, Walter P. Maksymowych, Robert D. Inman, Proton Rahman, Nigil Haroon, Lianne Gensler, Joseph E. Powell, Irene E. van der Horst-Bruinsma, Alex W. Hewitt, Jamie E. Craig, Lyndell L. Lim, Denis Wakefield, Peter McCluskey, Valentina Voigt, Peter Fleming, Mariapia Degli-Esposti, Jennifer J. Pointon, Michael H. Weisman, B. Paul Wordsworth, John D. Reveille, James T. Rosenbaum & Matthew A. Brown. (2015) Genetic Dissection of Acute Anterior Uveitis Reveals Similarities and Differences in Associations Observed With Ankylosing Spondylitis. Arthritis & Rheumatology 67:1, pages 140-151.
Crossref
Marcella Prete, Silvana Guerriero, Rosanna Dammacco, Maria Celeste Fatone, Angelo Vacca, Francesco Dammacco & Vito Racanelli. (2014) Autoimmune uveitis: a retrospective analysis of 104 patients from a tertiary reference center. Journal of Ophthalmic Inflammation and Infection 4:1.
Crossref
Inger Jorid Berg, Anne Grete Semb, Désirée van der Heijde, Tore K. Kvien, Jonny Hisdal, Inge C. Olsen, Hanne Dagfinrud & Sella A. Provan. (2014) Uveitis is associated with hypertension and atherosclerosis in patients with ankylosing spondylitis: A cross-sectional study. Seminars in Arthritis and Rheumatism 44:3, pages 309-313.
Crossref
Floris A van Gaalen, Willem Verduijn, Dave L Roelen, Tom W J Huizinga, D?siree van der Heijde & Ren? E M Toes. (2014) HLA-B60 and the HLA-B27/HLA-B60 genotype are not risk factors for acute anterior uveitis. Annals of the Rheumatic Diseases 73:3, pages 633-634.
Crossref
Scott J. Hebbring. (2014) The challenges, advantages and future of phenome‐wide association studies. Immunology 141:2, pages 157-165.
Crossref
Ulrich Weber, Susanne J. Pedersen, Veronika Zubler, Kaspar Rufibach, Stanley M. Chan, Robert G.W. Lambert, Mikkel Østergaard & Walter P. Maksymowych. (2014) Fat Infiltration on Magnetic Resonance Imaging of the Sacroiliac Joints Has Limited Diagnostic Utility in Nonradiographic Axial Spondyloarthritis. The Journal of Rheumatology 41:1, pages 75-83.
Crossref
Philip C. Robinson & Matthew A. Brown. (2014) Genetics of ankylosing spondylitis. Molecular Immunology 57:1, pages 2-11.
Crossref
Karin Brandauer, Arnd Heiligenhaus, Carsten Heinz, Maren Hennig, Friederike Mackensen, Kirsten Minden, Martina Niewerth, Uwe Pleyer, Vedat Schwenger, Sibylle Winterhalter & Markus Zeisbrich. 2014. Entzündliche Augenerkrankungen. Entzündliche Augenerkrankungen 307 330 .
Maike Kulbrock, Ottmar Distl & Bernhard Ohnesorge. (2013) A Review of Candidate Genes for Development of Equine Recurrent Uveitis. Journal of Equine Veterinary Science 33:11, pages 885-892.
Crossref
T. Lapp, D. Reinhold, D. Böhringer & T. Reinhard. (2013) Humanes Leukozytenantigensystem in der AugenheilkundeHuman leukocyte antigen (HLA) system in ophthalmology. Der Ophthalmologe 110:9, pages 849-861.
Crossref
Hongtao Dong, Qiuming Li, Ying Zhang, Wei Tan & Zhengxuan Jiang. (2013) IL23R Gene Confers Susceptibility to Ankylosing Spondylitis Concomitant with Uveitis in a Han Chinese Population. PLoS ONE 8:6, pages e67505.
Crossref
Gernot Steinwender, Ewald Lindner, Martin Weger, Sophie Plainer, Wilfried Renner, Navid Ardjomand & Yosuf El-Shabrawi. (2013) Association between Polymorphism of the Vitamin D Metabolism Gene CYP27B1 and HLA-B27-Associated Uveitis. Is a State of Relative Immunodeficiency Pathogenic in HLA B27-Positive Uveitis?. PLoS ONE 8:4, pages e62244.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.