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Gynecological Endocrinology Volume 30, 2014 - Issue 10
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Adenomyosis

Efficacy of dienogest in the treatment of symptomatic adenomyosis: a pilot study

Tetsuya HirataDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapanCorrespondence[email protected]
,
Gentaro IzumiDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Masashi TakamuraDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Ako SaitoDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Akari NakazawaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Miyuki HaradaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Yasushi HirotaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Kaori KogaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
,
Tomoyuki FujiiDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
&
Yutaka OsugaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo TokyoJapan
 show all
Pages 726-729 | Received 10 Feb 2014, Accepted 19 May 2014, Published online: 06 Jun 2014

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Juan Miao, Jing Lu, Juanjuan Tang & Pinhong Lu. (2022) Long-term treatment of dienogest with symptomatic adenomyosis: retrospective analysis of efficacy and safety in clinical practice. Gynecological Endocrinology 38:8, pages 656-660.
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Takashi Matsushima, Shigeo Akira, Koichi Yoneyama & Toshiyuki Takeshita. (2020) Recurrence of uterine adenomyosis after administration of gonadotropin-releasing hormone agonist and the efficacy of dienogest. Gynecological Endocrinology 36:6, pages 521-524.
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Articles from other publishers (35)

Vitaly B. Tskhay, Anna A. Bakunina & Gulnar T. Mikailli. (2023) Medical treatment of adenomyosis: a literature review. Gynecology 25:2, pages 133-139.
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Michel Canis & Sun-Wei Guo. (2023) In the thicket of fears, doubts, and murky facts: some reflections on treatment modalities for endometriosis-associated pain. Human Reproduction 38:7, pages 1245-1252.
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Tasuku Harada, Fuminori Taniguchi, Sun‐Wei Guo, Young Min Choi, Kutay Omer Biberoglu, Shaw‐Jenq Sean Tsai, Saeed Alborzi, Moamar Al‐Jefout, Amphan Chalermchokcharoenkit, Angela G. Sison‐Aguilar, Yoke‐Fai Fong, Hemantha Senanayake, Alexander Popov, Andon Hestiantoro & Yuval Kaufman. (2023) The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis. Reproductive Medicine and Biology 22:1.
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Alexandros Lazaridis, Alexandros L. Grammatis, Stuart Spencer & Martin Hirsch. (2022) Nonsurgical management of adenomyosis: an overview of current evidence. Current Opinion in Obstetrics & Gynecology 34:5, pages 315-323.
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Min Feng, Liang-Hsuan Chen, Le-Tien Hsu & Hsien-Ming Wu. (2022) Segmented in vitro fertilization and frozen embryo transfer in dienogest-treated patient with adenomyosis: A case report and lierature review. Taiwanese Journal of Obstetrics and Gynecology 61:5, pages 906-908.
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Kiran Kumar Rathinam, Justin Jacob Abraham, Heema Preethy S, Shevaani S.A, Maitrayee Sen, Melvin George & Priyadharshini A. (2022) Evaluation of pharmacological interventions in the management of adenomyosis: a systematic review. European Journal of Clinical Pharmacology 78:4, pages 531-545.
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Ezgi Darici & Engin Oral. 2022. Endometriosis and Adenomyosis. Endometriosis and Adenomyosis 531 556 .
Silvia Vannuccini & Sara Clemenza. 2022. Endometriosis and Adenomyosis. Endometriosis and Adenomyosis 423 440 .
Mohammed Nagdi Zaki, Aafia Mohammed Farooq Gheewale, Nada Ibrahim & Ibrahim Abd Elrahman. (2021) Late presentation of extrauterine adenomyomas after laparoscopic morcellation at hysterectomy: a case report. BMC Women's Health 21:1.
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Christina Anna Stratopoulou, Jacques Donnez & Marie-Madeleine Dolmans. (2021) Conservative Management of Uterine Adenomyosis: Medical vs. Surgical Approach. Journal of Clinical Medicine 10:21, pages 4878.
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Ahmed I. Hassanin, Ahmed A. Youssef, Asmaa M. Yousef & Mohammed K. Ali. (2021) Comparison of dienogest versus combined oral contraceptive pills in the treatment of women with adenomyosis: A randomized clinical trial. International Journal of Gynecology & Obstetrics 154:2, pages 263-269.
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Fady I. Sharara, Mira H. Kheil, Anis Feki, Sara Rahman, Jordan S. Klebanoff, Jean Marc Ayoubi & Gaby N. Moawad. (2021) Current and Prospective Treatment of Adenomyosis. Journal of Clinical Medicine 10:15, pages 3410.
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Julia E Dobrokhotova, Donna M Kalimatova, Irina Yu Ilyina & Igor I Grishin. (2021) Study of dienogest clinical efficacy in the treatment of adenomyosis. Journal of Endometriosis and Pelvic Pain Disorders 13:2, pages 136-141.
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A.M. Alcalde, M.A. Martínez-Zamora & F. Carmona. (2021) Adenomiosis. Una gran desconocida: ¿Qué debemos saber?. Clínica e Investigación en Ginecología y Obstetricia 48:2, pages 184-189.
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A.L. Tikhomirov, S.I. Sarsania, T.V. Dedy & E.A. Osetskaya. (2021) Clinical examples of the rational applying of the «gold standard» of hormonal therapy for endometriosis. Rossiiskii vestnik akushera-ginekologa 21:4, pages 99.
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Xiaocen Niu, Qun Luo, Chunfen Wang, Lihua Zhu & Lili Huang. (2021) Effects of Etonogestrel implants on pelvic pain and menstrual flow in women suffering from adenomyosis or endometriosis. Medicine 100:6, pages e24597.
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Masashi Takamura, Kaori Koga, Miyuki Harada, Yasushi Hirota, Tomoyuki Fujii & Yutaka Osuga. (2020) A case of hemorrhagic shock occurred during dienogest therapy for uterine adenomyosis. Journal of Obstetrics and Gynaecology Research 46:12, pages 2696-2700.
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Elena Andreeva & Yulia Absatarova. (2020) Triptorelin for the treatment of adenomyosis: A multicenter observational study of 465 women in Russia. International Journal of Gynecology & Obstetrics 151:3, pages 347-354.
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Rushania I. Gabidullina, Angelina I. Kuptsova, Ekaterina A. Koshelnikova, Fikret R. Nuhbala, Rufat R. Bagirli, Elmira R. Mingaleva & Endzhe A. Khaliullina. (2020) Adenomyosis: clinical aspects, impact on fertility and pregnancy outcome. Gynecology 22:4, pages 55-61.
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Adela G. Cope, Alessandra J. Ainsworth & Elizabeth A. Stewart. (2020) Current and Future Medical Therapies for Adenomyosis. Seminars in Reproductive Medicine 38:02/03, pages 151-156.
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Jing Xue, Lei Li, Feifei Li, Na Li, Tao Li & Changzhong Li. (2020) Expression of Lewis (b) blood group antigen interferes with oral dienogest therapy among women with adenomyosis. Journal of Reproductive Immunology 137, pages 103079.
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Khaleque N Khan, Akira Fujishita, Akemi Koshiba, Taisuke Mori, Haruo Kuroboshi, Hiroshi Ogi, Kyoko Itoh, Masahiro Nakashima & Jo Kitawaki. (2019) Biological differences between focal and diffuse adenomyosis and response to hormonal treatment. Reproductive BioMedicine Online 38:4, pages 634-646.
Crossref
C. Huchon, X. Fritel, M. Mimouni & A. Fauconnier. (2018) Dolor pélvico crónico de la mujer. Orientación diagnóstica y conducta práctica. EMC - Ginecología-Obstetricia 54:3, pages 1-8.
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Kazuaki Neriishi, Tetsuya Hirata, Shinya Fukuda, Gentaro Izumi, Akari Nakazawa, Naoko Yamamoto, Miyuki Harada, Yaushi Hirota, Kaori Koga, Osamu Wada-Hiraike, Tomoyuki Fujii & Yutaka Osuga. (2018) Long-term dienogest administration in patients with symptomatic adenomyosis. Journal of Obstetrics and Gynaecology Research 44:8, pages 1439-1444.
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Margit Dueholm. (2018) Minimally invasive treatment of adenomyosis. Best Practice & Research Clinical Obstetrics & Gynaecology 51, pages 119-137.
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Silvia Vannuccini, Stefano Luisi, Claudia Tosti, Flavia Sorbi & Felice Petraglia. (2018) Role of medical therapy in the management of uterine adenomyosis. Fertility and Sterility 109:3, pages 398-405.
Crossref
Yutaka Osuga, Haruka Fujimoto-Okabe & Atsushi Hagino. (2017) Evaluation of the efficacy and safety of dienogest in the treatment of painful symptoms in patients with adenomyosis: a randomized, double-blind, multicenter, placebo-controlled study. Fertility and Sterility 108:4, pages 673-678.
Crossref
Arisa Takeuchi, Kaori Koga, Mariko Miyashita, Tomoko Makabe, Fusako Sue, Miyuki Harada, Tetsuya Hirata, Yasushi Hirota, Tomoyuki Fujii & Yutaka Osuga. (2016) Dienogest reduces proliferation, NGF expression and nerve fiber density in human adenomyosis. European Journal of Obstetrics & Gynecology and Reproductive Biology 207, pages 157-161.
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Claudia Tosti, Libera Troìa, Silvia Vannuccini, Lucia Lazzeri, Stefano Luisi & Felice Petraglia. (2016) Current and Future Medical Treatment of Adenomyosis. Journal of Endometriosis and Pelvic Pain Disorders 8:4, pages 127-135.
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Khaleque N. Khan, Akira Fujishita, Michio Kitajima, Hideaki Masuzaki, Masahiro Nakashima & Jo Kitawaki. (2016) Biological differences between functionalis and basalis endometria in women with and without adenomyosis. European Journal of Obstetrics & Gynecology and Reproductive Biology 203, pages 49-55.
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Youn-Jee ChungSo-Yeon KangMi-Rang ChoiHyun-Hee ChoJang-Heub KimMee-Ran Kim. (2016) Robot-Assisted Laparoscopic Adenomyomectomy for Patients Who Want to Preserve Fertility. Yonsei Medical Journal 57:6, pages 1531.
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Muhammad Fawzy & Yasser Mesbah. (2015) Comparison of dienogest versus triptorelin acetate in premenopausal women with adenomyosis: a prospective clinical trial. Archives of Gynecology and Obstetrics 292:6, pages 1267-1271.
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L. Pelage, S. Fenomanana, J.-L. Brun, J.-M. Levaillant & H. Fernandez. (2015) Traitements de l’adénomyose (hors désir de grossesse). Gynécologie Obstétrique & Fertilité 43:5, pages 404-411.
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Matteo Morotti, Fausta Sozzi, Valentino Remorgida, Pier Luigi Venturini & Simone Ferrero. (2014) Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment. European Journal of Obstetrics & Gynecology and Reproductive Biology 183, pages 188-192.
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