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IVF and Luteal Phase Support

Which luteal phase support is better for each IVF stimulation protocol to achieve the highest pregnancy rate? A superiority randomized clinical trial

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Pages 902-908 | Received 15 May 2014, Accepted 09 Sep 2014, Published online: 30 Sep 2014

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Iva Pitner, Mislav Mikuš, Marina Šprem Goldštajn, Antonio Simone Laganà, Vito Chiantera, Federico Ferrari, Mohsin Shah, Maurizio Nicola D’Alterio, Salvatore Giovanni Vitale & Stefano Angioni. (2023) Effects of different progesterone levels on reproductive outcomes in assisted reproductive technologies: from molecular basis to treatment strategies. Gynecological Endocrinology 39:1.
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Xueyan Bai, Yang Zhang, Shan Liu, Danni Qu, Hui Su, Haiying Ren & Yuan Li. (2017) The decline in serum estradiol on the second day after oocyte retrieval affects the outcome of IVF/ICSI-ET treatment in high ovarian responders. Gynecological Endocrinology 33:6, pages 452-457.
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Articles from other publishers (26)

琰睿 陈. (2023) Clinical Research Progress on Luteal Phase Support of Antagonist in IVF-ET. Advances in Clinical Medicine 13:04, pages 5215-5222.
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Yang Liu, Yanzhi Wu, Zhengmei Pan, Fangjie Jiang, Youhui Lu & Yushi Meng. (2022) Single-Dose Versus Multiple-Dose GnRH Agonist for Luteal-Phase Support in Women Undergoing IVF/ICSI Cycles: A Network Meta-Analysis of Randomized Controlled Trials. Frontiers in Endocrinology 13.
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Jovan Bila & Svetlana Spremovic-Radjenovic. (2022) Adjuvant therapy in assisted fertilization procedures. Srpski arhiv za celokupno lekarstvo 150:11-12, pages 729-731.
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Gon Shoham, Milton Leong & Ariel Weissman. (2021) A 10-year follow‐up on the practice of luteal phase support using worldwide web‐based surveys. Reproductive Biology and Endocrinology 19:1.
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Hsien-Ming Wu, Hsun-Ming Chang & Peter C.K. Leung. (2021) Gonadotropin-releasing hormone analogs: Mechanisms of action and clinical applications in female reproduction. Frontiers in Neuroendocrinology 60, pages 100876.
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Nasrin Saharkhiz, Saghar Salehpour, Sedighe Hosseini, Hossein Hosseinirad & Leila Nazari. (2020) Effects of gonadotropin-releasing hormone agonist (GnRH-a) as luteal phase support in intracytoplasmic sperm injection (ICSI) cycles: a randomized controlled trial. Middle East Fertility Society Journal 25:1.
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Angela Baerwald & Roger Pierson. (2020) Ovarian follicular waves during the menstrual cycle: physiologic insights into novel approaches for ovarian stimulation. Fertility and Sterility 114:3, pages 443-457.
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Soghra Rabiei, Mohammad Fallah & Fatemeh Jamshidi. (2020) Comparison of Pregnancy Rate of Frozen Embryos by Two Methods: Long with GnRH Agonist and OCP with Estradiol Only. Avicenna Journal of Clinical Medicine 27:1, pages 5-12.
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Mengling Song, Chunlian Liu, Rong Hu, Feimiao Wang & Zhenghao Huo. (2019) Administration effects of single‑dose GnRH agonist for luteal support in females undertaking IVF/ICSI cycles: A meta‑analysis of randomized controlled trials. Experimental and Therapeutic Medicine.
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Rachel Cutting. 2018. Clinical Reproductive Science. Clinical Reproductive Science 341 349 .
Mauro Cozzolino, Amerigo Vitagliano, Maria Valentina Di Giovanni, Antonio Simone Laganà, Salvatore Giovanni Vitale, Mija Blaganje, Kristina Drusany Starič, Kobal Borut, Tito Silvio Patrelli & Marco Noventa. (2018) Ultrasound-guided embryo transfer: summary of the evidence and new perspectives. A systematic review and meta-analysis. Reproductive BioMedicine Online 36:5, pages 524-542.
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V. M. Denisova, E. V. Isakova & V. S. Korsak. (2017) Luteal phase support in ART programs (a review). Problemy reproduktsii 23:2, pages 37.
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Salvatore Gizzo, Marco Noventa, Michela Quaranta, Roberta Venturella, Amerigo Vitagliano, Michele Gangemi & Donato D'Antona. (2016) New frontiers in human assisted reproduction - from research to clinical practice: Several considerations. Molecular Medicine Reports 14:5, pages 4037-4041.
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Marco Noventa, Michela Quaranta, Amerigo Vitagliano, Vescio Cinthya, Romina Valentini, Tania Campagnaro, Roberto Marci, Rossana Di Paola, Carlo Alviggi, Michele Gangemi, Carlo Saccardi, Giovanni Battista Nardelli & Salvatore Gizzo. (2016) May Underdiagnosed Nutrition Imbalances Be Responsible for a Portion of So-Called Unexplained Infertility? From Diagnosis to Potential Treatment Options. Reproductive Sciences 23:6, pages 812-822.
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Hesham G Al-Inany, Mohamed A Youssef, Reuben Olugbenga Ayeleke, Julie Brown, Wai Sun Lam & Frank J Broekmans. (2016) Gonadotrophin-releasing hormone antagonists for assisted reproductive technology. Cochrane Database of Systematic Reviews 2016:8.
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W. P. Martins, R. A. Ferriani, P. A. Navarro & C. O. Nastri. (2016) GnRH agonist during luteal phase in women undergoing assisted reproductive techniques: systematic review and meta-analysis of randomized controlled trials. Ultrasound in Obstetrics & Gynecology 47:2, pages 144-151.
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Young Bae Hansen, Vibeke Myrhøj, Finn Stener Jørgensen & Steen Sørensen. (2016) Investigation on the ability of first trimester glycodelin and angiopoietin-2 to predict small-for-gestational age pregnancies at delivery. Clinical Chemistry and Laboratory Medicine (CCLM) 0:0.
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Salvatore Gizzo, Michela Quaranta, Alessandra Andrisani, Luciana Bordin, Amerigo Vitagliano, Federica Esposito, Roberta Venturella, Cecilia Zicchina, Michele Gangemi & Marco Noventa. (2016) Serum Stem Cell Factor Assay in Elderly Poor Responder Patients Undergoing IVF: A New Biomarker to Customize Follicle Aspiration Cycle by Cycle. Reproductive Sciences 23:1, pages 61-68.
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Stefano Palomba, Susanna Santagni & Giovanni Battista La Sala. (2015) Progesterone administration for luteal phase deficiency in human reproduction: an old or new issue?. Journal of Ovarian Research 8:1.
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Salvatore Gizzo, Alessandra Andrisani, Marco Noventa, Michela Quaranta, Federica Esposito, Decio Armanini, Michele Gangemi, Giovanni B Nardelli, Pietro Litta, Donato D’Antona & Guido Ambrosini. (2015) Menstrual cycle length: a surrogate measure of reproductive health capable of improving the accuracy of biochemical/sonographical ovarian reserve test in estimating the reproductive chances of women referred to ART. Reproductive Biology and Endocrinology 13:1.
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Gautam N. Allahbadia. (2015) The Ideal Stimulation Protocol: Is There One?. The Journal of Obstetrics and Gynecology of India 65:6, pages 357-361.
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Anna Ghirardello, Salvatore Gizzo, Marco Noventa, Michela Quaranta, Amerigo Vitagliano, Nicoletta Gallo, Giorgia Pantano, Marianna Beggio, Chiara Cosma, Michele Gangemi, Mario Plebani & Andrea Doria. (2015) Acute immunomodulatory changes during controlled ovarian stimulation: evidence from the first trial investigating the short-term effects of estradiol on biomarkers and B cells involved in autoimmunity. Journal of Assisted Reproduction and Genetics 32:12, pages 1765-1772.
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Charalampos S Siristatidis, Ahmed Gibreel, George Basios, Abha Maheshwari & Siladitya Bhattacharya. (2015) Gonadotrophin-releasing hormone agonist protocols for pituitary suppression in assisted reproduction. Cochrane Database of Systematic Reviews.
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SALVATORE GIZZO, ALESSANDRA ANDRISANI, MARCO NOVENTA, MICHELE GANGEMI, GIOVANNI BATTISTA NARDELLI & GUIDO AMBROSINI. (2015) Pretreatment with oral contraceptive pills to identify poor responders that may benefit from rLH supplementation during GnRH-antagonist treatment for IVF: A pilot perspective study proposal. Experimental and Therapeutic Medicine 10:5, pages 1692-1696.
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Salvatore Gizzo, Amerigo Vitagliano, Marco Noventa, Pietro Litta, Carlo Saccardi & Michela Quaranta. (2015) Surgery, endometriosis-related infertility and negative impact on ovarian reserve: “which came first, the hen or the egg?” An unresolved dilemma. Archives of Gynecology and Obstetrics 292:4, pages 709-711.
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SALVATORE GIZZO, ALESSANDRA ANDRISANI, MARCO NOVENTA, SERENA MANFÈ, ALESSANDRA OLIVA, MICHELE GANGEMI, GIOVANNI BATTISTA NARDELLI & GUIDO AMBROSINI. (2015) Recombinant LH supplementation during IVF cycles with a GnRH-antagonist in estimated poor responders: A cross-matched pilot investigation of the optimal daily dose and timing. Molecular Medicine Reports 12:3, pages 4219-4229.
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