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Gynecological Endocrinology Volume 31, 2015 - Issue 7
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Original Article

Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in the placenta of pregnancies complicated with preeclampsia

Peter ChedrauiEnrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador, ;Facultad de Ciencias Médicas, Research Area for Women’s Health, Institute of Biomedicine, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador, Correspondence[email protected]
,
Mariela E. AndradeEnrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador,
,
Danny Salazar-PousadaEnrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador, ;Facultad de Ciencias Médicas, Research Area for Women’s Health, Institute of Biomedicine, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador,
,
Gustavo S. EscobarFacultad de Ciencias Médicas, Research Area for Women’s Health, Institute of Biomedicine, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador,
,
Luis HidalgoEnrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador, ;Facultad de Ciencias Médicas, Research Area for Women’s Health, Institute of Biomedicine, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador,
,
Cecibel RamirezFacultad de Ciencias Médicas, Research Area for Women’s Health, Institute of Biomedicine, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador,
,
Marc E. A. SpaandermanSchool for Oncology and Developmental Biology Maastricht (GROW), Maastricht University, Maastricht, the Netherlands, and
,
Boris W. KramerSchool for Oncology and Developmental Biology Maastricht (GROW), Maastricht University, Maastricht, the Netherlands, and ;Department of Pediatrics, Division of Neonatology, Maastricht University Medical Center, Maastricht, the Netherlands
&
Antonio W. D. GavilanesFacultad de Ciencias Médicas, Research Area for Women’s Health, Institute of Biomedicine, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador, ;School for Oncology and Developmental Biology Maastricht (GROW), Maastricht University, Maastricht, the Netherlands, and ;Department of Pediatrics, Division of Neonatology, Maastricht University Medical Center, Maastricht, the Netherlands
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Pages 569-572 | Received 01 Feb 2015, Accepted 15 Mar 2015, Published online: 02 Jun 2015

Citations (13)

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Sadia Mahmood, Hooria Younas, Amna Younus & Sammar Nathenial. (2021) A narrative review on the role of folate-mediated one-carbon metabolism and its associated gene polymorphisms in posing risk to preeclampsia. Clinical and Experimental Hypertension 43:6, pages 487-504.
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Articles from other publishers (12)

Olesya Efremova, Irina Ponomarenko & Mikhail Churnosov. (2022) Role of intergenic interactions among folate cycle genes in the development of fetal growth retardation. Reproductive and Developmental Medicine 7:1, pages 32-37.
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Xiaosong Yuan, Xiaoya Han, Wenbo Zhou, Wei Long, Huiyan Wang, Bin Yu & Bin Zhang. (2022) Association of folate and vitamin B12 imbalance with adverse pregnancy outcomes among 11,549 pregnant women: An observational cohort study. Frontiers in Nutrition 9.
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Maria Paola Bertuccio, Monica Currò, Daniela Caccamo & Riccardo Ientile. (2022) Dietary Intake and Genetic Background Influence Vitamin Needs during Pregnancy. Healthcare 10:5, pages 768.
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Kirk P. Conrad, Ira M. Bernstein & Alison D. Gernand. 2022. Chesley's Hypertensive Disorders in Pregnancy. Chesley's Hypertensive Disorders in Pregnancy 71 94 .
Tanja Jankovic‐Karasoulos, Denise L. Furness, Shalem Y. Leemaqz, Gustaaf A. Dekker, Luke E. Grzeskowiak, Jessica A. Grieger, Prabha H. Andraweera, Dylan McCullough, Dale McAninch, Lesley M. McCowan, Tina Bianco‐Miotto & Claire T. Roberts. (2020) Maternal folate, one‐carbon metabolism and pregnancy outcomes. Maternal & Child Nutrition 17:1.
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Giulia F. Del Gobbo, Chaini Konwar & Wendy P. Robinson. (2019) The significance of the placental genome and methylome in fetal and maternal health. Human Genetics 139:9, pages 1183-1196.
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Abbas Mohammadpour‐Gharehbagh, Danial Jahantigh, Mohsen Saravani, Mahdiyeh Harati‐Sadegh, Rostam Maruie‐Milan, Batool Teimoori & Saeedeh Salimi. (2019) Impact of HOTAIR variants on preeclampsia susceptibility based on blood and placenta and in silico analysis . IUBMB Life 71:9, pages 1367-1381.
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Hui Mo, Meng Rao, Gang Wang, Yan‐Xi Long, Hua‐Wei Wang & Li Tang. (2019) Polymorphism of MTHFR 1298A>C in relation to adverse pregnancy outcomes in Chinese populations . Molecular Genetics & Genomic Medicine 7:5, pages e642.
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M.C. Ergoren & P. Tulay. (2019) Investigation of potential biomarkers for thrombosis related diseases in Turkish Cypriot population. International Journal of Biological Macromolecules 124, pages 515-518.
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Rafael Tomoya Michita, Valéria de Lima Kaminski & José Artur Bogo Chies. (2018) Genetic Variants in Preeclampsia: Lessons From Studies in Latin-American Populations. Frontiers in Physiology 9.
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Giulia F. Del Gobbo, E. Magda Price, Courtney W. Hanna & Wendy P. Robinson. (2018) No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation. Clinical Epigenetics 10:1.
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Abbas Mohammadpour‐Gharehbagh, Batool Teimoori, Mehrnaz Narooei‐nejad, Mehrnaz Mehrabani, Ramin Saravani & Saeedeh Salimi. (2017) The association of the placental MTHFR 3′‐UTR polymorphisms, promoter methylation, and MTHFR expression with preeclampsia. Journal of Cellular Biochemistry 119:2, pages 1346-1354.
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