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Gynecological Endocrinology Volume 13, 1999 - Issue 4
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Original Article

Double-blind, placebo-controlled study of the effects of tibolone on bone mineral density in postmenopausal osteoporotic women with and without previous fractures

P. W. Pavlov Department of Orthopedic Surgery, Sint Maartenskliniek, Nijmegen, The Netherlands
,
J. Ginsburg Department of Endocrinology, The Royal Free Hospital, London, UK
,
P. M. Kicovic Reproductive Medicine Section, MRDU, NV Organon, Oss, The Netherlands
,
D. B. van der Schaaf Department of Orthopedic Surgery, Sint Maartenskliniek, Nijmegen, The Netherlands
,
G. Prelevic Department of Endocrinology, The Royal Free Hospital, London, UK
&
H. J. T. Coelingh Bennink Reproductive Medicine Section, MRDU, NV Organon, Oss, The NetherlandsView further author information
Pages 230-237 | Published online: 05 Aug 2009

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Andrew Grey. (2007) Emerging pharmacologic therapies for osteoporosis. Expert Opinion on Emerging Drugs 12:3, pages 493-508.
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Eric J MacLaughlin, Rebecca B Sleeper, Danny McNatty & Cynthia L Raehl. (2006) Management of Age-Related Osteoporosis and Prevention of Associated Fractures. Therapeutics and Clinical Risk Management 2:3, pages 281-295.
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Andrew Grey & Ian R Reid. (2005) Emerging and potential therapies for osteoporosis. Expert Opinion on Investigational Drugs 14:3, pages 265-278.
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Jean-Pierre Devogelaer. (2004) A review of the effects of tibolone on the skeleton. Expert Opinion on Pharmacotherapy 5:4, pages 941-949.
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O. Ylikorkala & M. Metsä-Heikkilä. (2002) Hormone replacement therapy in women with a history of breast cancer. Gynecological Endocrinology 16:6, pages 469-478.
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Ilgiz V. Galyautdinov, Zarema R. Khairullina, Valery P. Sametov, Zabir S. Muslimov, Leonard M. Khalilov & Victor N. Odinokov. (2016) 7α-Alkylation and 7,7-bis-alkylation of 20-hydroxyecdysone with propargyl bromide in a lithium–ammonia solution and catalytic reductive spirocyclization of 7,7-bis(2-propyn-1-yl)-14-deoxy-Δ8(14)-20-hydroxyecdysone. Steroids 107, pages 121-127.
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Ilgiz V. Galyautdinov, Zarema R. Khairullina, Elvira R. Zaripova, Valery P. Sametov, Ekaterina S. Mescheryakova, Zabir S. Muslimov, Oleg S. Mozgovoi, Leonard M. Khalilov & Victor N. Odinokov. (2015) Stereospecific 7α-alkylation of 20-hydroxyecdysone in a lithium–ammonia solution. Steroids 98, pages 122-125.
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A. El Maghraoui, A. Rezqi, A. Mounach, L. Achemlal, A. Bezza & I. Ghozlani. (2013) Systematic vertebral fracture assessment in asymptomatic postmenopausal women. Bone 52:1, pages 176-180.
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A. El Maghraoui, A. Mounach, A. Rezqi, L. Achemlal, A. Bezza & I. Ghozlani. (2012) Vertebral fracture assessment in asymptomatic men and its impact on management. Bone 50:4, pages 853-857.
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A. El Maghraoui, F. Morjane, A. Nouijai, L. Achemlal, A. Bezza & I. Ghozlani.. (2009) Vertebral fracture assessment in Moroccan women: Prevalence and risk factors. Maturitas 62:2, pages 171-175.
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A. El Maghraoui, A. Mounach, S. Gassim & M. Ghazi. (2008) Vertebral fracture assessment in healthy men: Prevalence and risk factors. Bone 43:3, pages 544-548.
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P. D. Delmas, S. R. Davis, J. Hensen, S. Adami, S. van Os & E. A. Nijland. (2008) Effects of tibolone and raloxifene on bone mineral density in osteopenic postmenopausal women. Osteoporosis International 19:8, pages 1153-1160.
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E.A. Nijland, W.C.M. Weijmar Schultz & S.R. Davis. (2007) Effects of tibolone and raloxifene on health-related quality of life and sexual function. Maturitas 58:2, pages 164-173.
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. 2006. Wiley Handbook of Current and Emerging Drug Therapies. Wiley Handbook of Current and Emerging Drug Therapies.
Hakan Kiran & Gurkan Kiran. (2005) Short-term effects of hormone therapy on serum C-reactive protein levels in postmenopausal women. Archives of Gynecology and Obstetrics 274:1, pages 9-12.
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Cynthia J Lees, Antwan G. H Ederveen, Cees P. M Spanjers & Thomas B Clarkson. (2005) Effects of tibolone on bone quality in ovariectomized monkeys. Menopause 12:5, pages 613-618.
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P. Kenemans & L. Speroff. (2005) Tibolone: Clinical recommendations and practical guidelines. Maturitas 51:1, pages 21-28.
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Gordana M. Prelevic, Athina Markou, Amanda Arnold, Clive Bartram, Zarko Puzigaca & Jean Ginsburg. (2004) The effect of tibolone on bone mineral density in postmenopausal women with osteopenia or osteoporosis—8 years follow-up. Maturitas 47:3, pages 229-234.
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R.M. Francis, S.P. Baillie, A.J. Chuck, P.R. Crook, N. Dunn, J.N. Fordham, C. Kelly & A. Rodgers. (2004) Acute and long-term management of patients with vertebral fractures. QJM 97:2, pages 63-74.
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Stephen F. Hodgson, Nelson B. Watts, John P. Bilezikian, Bart L. Clarke, T. Kenney Gray, David W. Harris, C. Conrad JohnstonJrJr, Michael Kleerekoper, Robert Lindsay, Marjorie M. Luckey, Michael R. McClung, Howard R. Nankin, Steven M. Petak, Robert R. Recker, Robert J. Anderson, Donald A. Bergman, Zachary T. Bloomgarden, Richard A. Dickey, Pasquale J. Palumbo, Anne L. Peters, Herbert I. Rettinger, Helena W. Rodbard & Harvey A. Rubenstein. (2003) American Association of Clinical Endocrinologists Medical Guidelines For Clinical Practice For The Prevention and Treatment of Postmenopausal Osteoporosis: 2001 Edition, With Selected Updates For 2003. Endocrine Practice 9:6, pages 544-564.
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John E Morley & Fran E Kaiser. (2003) Female sexuality. Medical Clinics of North America 87:5, pages 1077-1090.
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J. E. Morley & H. M. Perry. (2003) Androgens and Women at the Menopause and Beyond. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 58:5, pages M409-M416.
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. (2003) Osteoporosis postmenopáusica. Guía de práctica clínica. Revista Clínica Española 203:10, pages 496-506.
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Inka Wiegratz, Franz Starflinger, Wolfgang Tetzloff, Beate Leifels-Fischer, Frans A Helmond, Jeanne S.E Dericks-Tan & Herbert Kuhl. (2002) Effect of tibolone compared with sequential hormone replacement therapy on carbohydrate metabolism in postmenopausal women. Maturitas 41:2, pages 133-141.
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S. Palacios. (2001) Tibolone: a tissue-specific approach to the menopause. European Heart Journal Supplements 3:suppl_M, pages M12-M16.
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Santiago Palacios. (2001) Tibolone: what does tissue specific activity mean?. Maturitas 37:3, pages 159-165.
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K. Brooke-Wavell, G.M. Prelevic, C. Bakridan & J. Ginsburg. (2001) Effects of physical activity and menopausal hormone replacement therapy on postural stability in postmenopausal women — a cross-sectional study. Maturitas 37:3, pages 167-172.
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Robert Lindsay & Felicia Cosman. 2001. Osteoporosis. Osteoporosis 577 601 .
M. Dowsett. (2000) Use of risk determinants for different breast cancer prevention strategies. European Journal of Cancer 36:10, pages 1283-1287.
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K. Brooke-Wavell, G.M. Prelevic, C. Bartram & J. Ginsburg. (2000) The influence of physical activity on the response of bone mineral density to 5 years tibolone. Maturitas 35:3, pages 229-235.
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T Simoncini & A.R Genazzani. (2000) Tibolone inhibits leukocyte adhesion molecule expression in human endothelial cells. Molecular and Cellular Endocrinology 162:1-2, pages 87-94.
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J. Zochling & P. N. Sambrook. 2000. Sex Hormone Replacement Therapy. Sex Hormone Replacement Therapy 11 29 .

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