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Original Article

Neuropeptide Y, leptin, galanin and insulin in women with polycystic ovary syndrome

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Pages 344-351 | Published online: 05 Aug 2009

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Read on this site (5)

Eleni Bili, Evdokia Karagianni, Dimitrios G. Goulis, Konstantinos A. Toulis, Grigoris Grimbizis & Basil C. Tarlatzis. (2017) Galanin in pregnancy: Is there an association with birth weight and gestational diabetes?. The Journal of Maternal-Fetal & Neonatal Medicine 30:23, pages 2812-2817.
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Bożena Bidzińska-Speichert, Agnieszka Lenarcik, Urszula Tworowska-Bardzińska, Ryszard Ślęzak, Grażyna Bednarek-Tupikowska & Andrzej Milewicz. (2012) Pro12Ala PPAR γ2 gene polymorphism in PCOS women: the role of compounds regulating satiety. Gynecological Endocrinology 28:3, pages 195-198.
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Hiroyuki Shimizu & Masatomo Mori. (2005) The brain–adipose axis: A review of involvement of molecules. Nutritional Neuroscience 8:1, pages 7-20.
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Suke Wang, Joyce Hwa & Geoffrey Varty. (2000) Galanin receptors and their therapeutic potential. Emerging Drugs 5:4, pages 415-440.
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Articles from other publishers (35)

Patrycja Kurowska, Monika Dawid, Julia Oprocha, Natalia Respekta, Loïse Serra, Anthony Estienne, Piotr Pawlicki, Małgorzata Kotula-Balak, Fabrice Guérif, Joelle Dupont & Agnieszka Rak. (2023) Spexin role in human granulosa cells physiology and PCOS: expression and negative impact on steroidogenesis and proliferation. Biology of Reproduction 109:5, pages 705-719.
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Wei-hong Chen, Yan-chuan Shi, Qiao-yi Huang, Jia-ming Chen, Zhi-yi Wang, Shu Lin & Qi-yang Shi. (2023) Potential for NPY receptor–related therapies for polycystic ovary syndrome: an updated review. Hormones 22:3, pages 441-451.
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Yoko Urata, Reza Salehi, Brandon A. Wyse, Sahar Jahangiri, Clifford L. Librach, Chii-Ruey Tzeng, Yutaka Osuga & Benjamin Tsang. (2023) Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects. Journal of Ovarian Research 16:1.
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Priyankur Roy, Prabhat Agrawal, Prashant Gupta, Ruchika Garg & Juhi Srivastava. (2023) Advances in Neuroendocrine Research on Polycystic Ovary Syndrome: New Hope for Treatment Decoding the Link between Hormones and the Brain. Journal of South Asian Federation of Obstetrics and Gynaecology 15:1, pages 114-119.
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Yang Li, Wang Zhi, Dong Haoxu, Wang Qing, Cheng Ling, Yi Ping & Huang Dongmei. (2022) Effects of electroacupuncture on the expression of hypothalamic neuropeptide Y and ghrelin in pubertal rats with polycystic ovary syndrome. PLOS ONE 17:6, pages e0259609.
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Izzati Mohd Zahir, Satoshi Ogawa, Nisha Angela Dominic, Tomoko Soga & Ishwar S. Parhar. (2022) Spexin and Galanin in Metabolic Functions and Social Behaviors With a Focus on Non-Mammalian Vertebrates. Frontiers in Endocrinology 13.
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Ismail Guzelkas, Zerrin Orbak, Hakan Doneray, Nurinnisa Ozturk & Nevin Sagsoz. (2022) Serum kisspeptin, leptin, neuropeptide Y, and neurokinin B levels in adolescents with polycystic ovary syndrome. Journal of Pediatric Endocrinology and Metabolism 35:4, pages 481-487.
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Umit Gorkem & Engin Yildirim. (2022) Alarin: A new predictive marker in infertile women with polycystic ovary syndrome: A case–control study. Journal of Obstetrics and Gynaecology Research 48:4, pages 980-986.
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Anna Szeliga, Ewa Rudnicka, Marzena Maciejewska-Jeske, Marek Kucharski, Anna Kostrzak, Marta Hajbos, Olga Niwczyk, Roman Smolarczyk & Blazej Meczekalski. (2022) Neuroendocrine Determinants of Polycystic Ovary Syndrome. International Journal of Environmental Research and Public Health 19:5, pages 3089.
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Miłosz Gołyszny, Ewa Obuchowicz & Michał Zieliński. (2022) Neuropeptides as regulators of the hypothalamus-pituitary-gonadal (HPG) axis activity and their putative roles in stress-induced fertility disorders. Neuropeptides 91, pages 102216.
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WaliuOlatunbosun Oladosu, OlanrewajuSaheed Jimoh, WasiuAdebisi Adeniyi, AdewaleMukaila Alayo, AminatOlayinka Ahmed, SekinatTitilayo Raji-Olarinoye, TaofeeqAbiodun Ajadi & SikiruAbayomi Biliaminu. (2022) Pattern of common hormonal disorders among patients with polycystic ovarian syndrome at a tertiary health facility in Nigeria. Nigerian Journal of Medicine 31:1, pages 92.
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Ying Liu, Yu-Chen Xu, Yu-Gui Cui, Shi-Wen Jiang, Fei-Yang Diao, Jia-Yin Liu & Xiang Ma. (2022) Androgen Excess Increases Food Intake in a Rat Polycystic Ovary Syndrome Model by Downregulating Hypothalamus Insulin and Leptin Signaling Pathways Preceding Weight Gain. Neuroendocrinology 112:10, pages 966-981.
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Sunduz Ozlem Altinkaya. (2021) Galanin and glypican-4 levels depending on metabolic and cardiovascular risk factors in patients with polycystic ovary syndrome. Archives of Endocrinology and Metabolism.
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Marta Tyszkiewicz-Nwafor, Katarzyna Jowik, Agata Dutkiewicz, Agata Krasinska, Natalia Pytlinska, Monika Dmitrzak-Weglarz, Marta Suminska, Agata Pruciak, Bogda Skowronska & Agnieszka Slopien. (2021) Neuropeptide Y and Peptide YY in Association with Depressive Symptoms and Eating Behaviours in Adolescents across the Weight Spectrum: From Anorexia Nervosa to Obesity. Nutrients 13:2, pages 598.
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Farahnaz Azin & Homayoun Khazali. (2020) Neuropeptide galanin and its effects on metabolic and reproductive disturbances in female rats with estradiol valerate (EV) - Induced polycystic ovary syndrome (PCOS). Neuropeptides 80, pages 102026.
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Tolga KOSECI, Omer KAYA, Veysel HAKSOYLER, Didem DERICI YILDIRIM & Kerem SEZER. (2019) Investigation of the relationship between insulin resistance and neuropeptide Y levels in polycystic ovary syndromePolikistik over sendromunda insülin rezistansı ve nöropeptid Y düzeyleri arasındaki ilişkinin araştırılması. Marmara Medical Journal 32:1, pages 1-6.
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Romualdi Daniela, Immediata Valentina, De Cicco Simona, Tagliafem Valeria & Lanzone Antonio. (2018) Neuroendocrine Regulation of Food Intake in Polycystic Ovary Syndrome. Reproductive Sciences 25:5, pages 644-653.
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Holly R. Harris & Kathryn L. Terry. (2016) Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review. Fertility Research and Practice 2:1.
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Dinka Pavicic Baldani, Lana Skrgatic & Roya Ougouag. (2015) Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women. International Journal of Endocrinology 2015, pages 1-17.
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A. Gonzalez-Bulnes & S. Astiz. 2014. Handbook of diet and nutrition in the menstrual cycle, periconception and fertility. Handbook of diet and nutrition in the menstrual cycle, periconception and fertility 401 412 .
Raymond M Anchan, Jennifer Lindsey, Edward Newton, John Thyfault & James DeVente. (2013) Peripartum changes in the orexigenic CNS peptide neuropeptide-Y in gestational diabetics. Journal of Diabetes Research and Clinical Metabolism 2:1, pages 23.
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Miguel A. Velazquez & Tom P. Fleming. 2013. Oogenesis. Oogenesis 329 351 .
S.S. Lim, M.J. Davies, R.J. Norman & L.J. Moran. (2012) Overweight, obesity and central obesity in women with polycystic ovary syndrome: a systematic review and meta-analysis. Human Reproduction Update 18:6, pages 618-637.
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Soyoung Kim, Yoojeong Jin, Youngshim Choi & Taesun Park. (2011) Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice. Biochemical Pharmacology 81:11, pages 1343-1351.
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Maria Orbetzova, Blagovest Pehlivanov, Mitko Mitkov, Iliana Atanassova, Zdravko Kamenov, Georgi Kolarov & Gencho Genchev. (2011) Effect of Short-Term Standard Therapeutic Regimens on Neuropeptide Y and Adipose Tissue Hormones in Overweight Insulinresistant Women with Polycystic Ovary Syndrome. Folia Medica 53:3.
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Christopher J Brewer & Adam H Balen. (2010) The adverse effects of obesity on conception and implantation. REPRODUCTION 140:3, pages 347-364.
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Aleksandra Marciniak, Jolanta Nawrocka-Rutkowska, Agnieszka Brodowska, Robert Sienkiewicz, Iwona Szydłowska & Andrzej Starczewski. (2009) Leptin concentrations in patients with polycystic ovary syndrome before and after met-formin treatment depending on insulin resistance, body mass index and androgen con-centrations--introductory report.. Folia Histochemica et Cytobiologica 47:2.
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N J Poritsanos, T M Mizuno, M-E Lautatzis & M Vrontakis. (2009) Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. International Journal of Obesity 33:12, pages 1381-1389.
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Louise Mannerås, Stefan Cajander, Malin Lönn & Elisabet Stener-Victorin. (2009) Acupuncture and exercise restore adipose tissue expression of sympathetic markers and improve ovarian morphology in rats with dihydrotestosterone-induced PCOS. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 296:4, pages R1124-R1131.
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Daniela Romualdi, Laura De Marinis, Giuseppe Campagna, Caterina Proto, Antonio Lanzone & Maurizio Guido. (2008) Alteration of ghrelin-neuropeptide Y network in obese patients with polycystic ovary syndrome: role of hyperinsulinism. Clinical Endocrinology 69:4, pages 562-567.
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Carmen N. Mircea, Marla E. Lujan & Roger A. Pierson. (2007) Metabolic Fuel and Clinical Implications for Female Reproduction. Journal of Obstetrics and Gynaecology Canada 29:11, pages 887-902.
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M.L. Hendriks, J.C.F. Ket, P.G.A. Hompes, R. Homburg & C.B. Lambalk. (2007) Why does ovarian surgery in PCOS help? Insight into the endocrine implications of ovarian surgery for ovulation induction in polycystic ovary syndrome. Human Reproduction Update 13:3, pages 249-264.
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Urho Abramov, Anders Florén, David J. Echevarria, Ariel Brewer, Honeyleen Manuzon, John K. Robinson, Tamas Bartfai, Eero Vasar & Ülo Langel. (2004) Regulation of feeding by galnon. Neuropeptides 38:1, pages 55-61.
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Denis A. Magoffin, Priya S. Duggal & Robert J. Norman. 2003. Leptin and Reproduction. Leptin and Reproduction 333 345 .
Brinda N. Kalro, Tammy L. Loucks & Sarah L. Berga. (2001) Neuromodulation in Polycystic Ovary Syndrome. Obstetrics and Gynecology Clinics of North America 28:1, pages 35-62.
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