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Platelets Volume 21, 2010 - Issue 2
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Research Article

VerifyNow and VASP phosphorylation assays give similar results for patients receiving clopidogrel, but they do not always correlate with platelet aggregation

Audrey Bidet Centre de Référence des Pathologies Plaquettaires, Laboratoire d’hématologie, Pessac, France
,
Catherine Jais Département des Soins Intensifs de Cardiologie, Hôpital Cardiologique, CHU de Bordeaux, Pessac, France
,
Etienne Puymirat Département des Soins Intensifs de Cardiologie, Hôpital Cardiologique, CHU de Bordeaux, Pessac, France
,
Pierre Coste Département des Soins Intensifs de Cardiologie, Hôpital Cardiologique, CHU de Bordeaux, Pessac, France
,
Alan Nurden Centre de Référence des Pathologies Plaquettaires, Laboratoire d’hématologie, Pessac, France
,
Joseph Jakubowski Lilly Research Laboratories, Indianapolis, IN, USA
&
Paquita Nurden Centre de Référence des Pathologies Plaquettaires, Laboratoire d’hématologie, Pessac, FranceCorrespondence[email protected]
, MD, PhD show all
Pages 94-100 | Received 11 Sep 2009, Accepted 23 Oct 2009, Published online: 12 Feb 2010

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Gilles Lemesle, Jean-Baptiste Landel, Anne Bauters, Cédric Delhaye, Laurent Bonello, Arnaud Sudre, Sophie Susen, Christophe Bauters & Jean-Marc Lablanche. (2014) Poor agreement between light transmission aggregometry, Verify Now P2Y12 and vasodilatator-stimulated phosphoprotein for clopidogrel low-response assessment: A potential explanation of negative results of recent randomized trials. Platelets 25:7, pages 499-505.
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Paul Harrison. (2012) Advances in the monitoring of anti-P2Y12 therapy. Platelets 23:7, pages 510-525.
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Sung Gyun Ahn, Seung-Hwan Lee, Joong Kyung Sung, Jang-Young Kim & Junghan Yoon. (2011) Intra-individual variability of residual platelet reactivity assessed by the VerifyNow-P2Y12 assay in patients with clopidogrel resistance after percutaneous coronary intervention. Platelets 22:4, pages 305-307.
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N Marsousi, CF Samer, P Fontana, JL Reny, S Rudaz, JA Desmeules & Y Daali. (2016) Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach. Clinical Pharmacology & Therapeutics 100:3, pages 295-304.
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Sandra Le Quellec, Jean-Claude Bordet, Claude Negrier & Yesim Dargaud. (2017) Comparison of current platelet functional tests for the assessment of aspirin and clopidogrel response. Thrombosis and Haemostasis 116:10, pages 638-650.
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Vikram Khanna, Alex Hobson, Rand Mikael, Nalyaka Sambu, Nicola Englyst & Nick Curzen. (2017) Does the VerifyNow P2Y12 assay overestimate “therapeutic response” to clopidogrel?. Thrombosis and Haemostasis 111:06, pages 1150-1159.
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Sandra A Weiss & William Weintraub. (2012) Overview of platelet functional testing methods and their controversial role in the clopidogrel-treated patient. Interventional Cardiology 4:5, pages 537-547.
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Ravi Patni, M. Asghar Nawaz, Antanas Macys, K.M. John Chan & P. Punjabi. (2012) Assessment of Platelet Function in Patients on Antiplatelet Therapy Undergoing Cardiac Surgery: A Review. Heart, Lung and Circulation 21:8, pages 455-462.
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M J Sheffield, D K Lambert, V L Baer, E Henry, A Butler, G L Snow & R D Christensen. (2011) Effect of ampicillin on bleeding time in very low birth-weight neonates during the first week after birth. Journal of Perinatology 31:7, pages 477-480.
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Stacy E. F. Melanson. (2011) Literature Review on Point-of-Care Testing (August 2009-December 2010). Point of Care: The Journal of Near-Patient Testing & Technology 10:2, pages 63-68.
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Alf-Aage R Pettersen, Harald Arnesen, Trine B Opstad & Ingebjorg Seljeflot. (2011) The influence of CYP 2C19*2 polymorphism on platelet function testing during single antiplatelet treatment with clopidogrel. Thrombosis Journal 9:1, pages 4.
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Louis M. Fink, Richard A. Marlar & Jonathan L. Miller. 2011. Henry's Clinical Diagnosis and Management by Laboratory Methods. Henry's Clinical Diagnosis and Management by Laboratory Methods 831 842 .
Lawrence Brass. (2010) Understanding and Evaluating Platelet Function. Hematology 2010:1, pages 387-396.
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