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Original Article (Fast Track)

Impact of non-inhibited platelet supplementation on platelet reactivity in patients treated with prasugrel or ticagrelor for an acute coronary syndrome: An ex vivo study

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Pages 324-330 | Received 01 Feb 2015, Accepted 25 Mar 2015, Published online: 23 Apr 2015

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M.U. Zafar, J.J. Badimon & G. Escolar. (2018) Incomplete reversibility of platelet inhibition following prolonged exposure to ticagrelor: comment. Journal of Thrombosis and Haemostasis 16:3, pages 605-606.
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P. Gaussem, A.-C. Martin, T. Belleville-Rolland, D. Helley, C. Bachelot-Loza & A. Godier. (2017) Antiplaquettaires et transfusion. Transfusion Clinique et Biologique 24:3, pages 160-165.
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Paul KrugerNoel ChanJohn W. Eikelboom. (2017) Platelet Transfusion for Ticagrelor Reversal. Circulation: Cardiovascular Interventions 10:8.
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Crossref
Marie Lordkipanidzé. (2015) Is platelet transfusion the solution to reverse platelet inhibition in patients on triple antiplatelet therapy?. Thrombosis Research 136:6, pages 1057-1058.
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Dirk SibbingSteffen Massberg. (2015) Restoring Platelet Function in Patients on P2Y 12 Receptor Inhibitor Treatment . Circulation: Cardiovascular Interventions 8:11.
Crossref

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