Advanced search
Publication Cover
International Journal of Radiation Biology Volume 91, 2015 - Issue 1
Submit an article Journal homepage
455
Views
25
CrossRef citations to date
0
Altmetric
RADIOSENSITISATION OF GLIOBLASTOMA CELLS USING A HISTONE DEACETYLASE INHIBITOR

Radiosensitization of glioblastoma cells using a histone deacetylase inhibitor (SAHA) comparing carbon ions with X-rays

Lara BarazzuolIon Beam Centre, University of Surrey, Guildford, Surrey, UKCorrespondence[email protected]
,
J. Charles G. JeynesIon Beam Centre, University of Surrey, Guildford, Surrey, UK
,
Michael J. MerchantIon Beam Centre, University of Surrey, Guildford, Surrey, UK
,
Anne-Catherine WéraIon Beam Centre, University of Surrey, Guildford, Surrey, UK
,
Miriam A. BarryIon Beam Centre, University of Surrey, Guildford, Surrey, UK;Royal Surrey County Hospital, Guildford, Surrey, UK
,
Karen J. KirkbyIon Beam Centre, University of Surrey, Guildford, Surrey, UK
&
Masao SuzukiNational Institute of Radiobiological Sciences (HIMAC), Chiba, Japan
 show all
Pages 90-98 | Received 15 Jan 2014, Accepted 19 Jun 2014, Published online: 21 Jul 2014

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

John E. Moulder. (2019) Chemical radiosensitizers: the Journal history. International Journal of Radiation Biology 95:7, pages 940-944.
Read now

Articles from other publishers (24)

Lina Yin, Yun Gao, Xuxia Zhang, Jing Wang, Defang Ding, Yaping Zhang, Junxiang Zhang & Honghong Chen. (2016) Niclosamide sensitizes triple-negative breast cancer cells to ionizing radiation in association with the inhibition of Wnt/β-catenin signaling. Oncotarget 7:27, pages 42126-42138.
Crossref
Liesbeth Everix, Elsie Neo Seane, Thomas Ebenhan, Ingeborg Goethals & Julie Bolcaen. (2023) Introducing HDAC-Targeting Radiopharmaceuticals for Glioblastoma Imaging and Therapy. Pharmaceuticals 16:2, pages 227.
Crossref
Semer Maksoud. (2022) The DNA Double-Strand Break Repair in Glioma: Molecular Players and Therapeutic Strategies. Molecular Neurobiology 59:9, pages 5326-5365.
Crossref
Ankita Nachankar, Takahiro Oike, Hirofumi Hanaoka, Ayaka Kanai, Hiro Sato, Yukari Yoshida, Hideru Obinata, Makoto Sakai, Naoto Osu, Yuka Hirota, Akihisa Takahashi, Atsushi Shibata & Tatsuya Ohno. (2021) 64Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity. Cancers 13:24, pages 6159.
Crossref
Jonathan Dow, Adam Krysztofiak, Yanfeng Liu, Daniel A. Colon-Rios, Faye A. Rogers & Peter M. Glazer. (2021) Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of DNA Repair. Molecular Cancer Research 19:12, pages 2057-2067.
Crossref
Alicia M. Johnson, Paula V. Bennett, Katherine Z. Sanidad, Anthony Hoang, James H. Jardine, Deborah J. Keszenman & Paul F. Wilson. (2021) Evaluation of Histone Deacetylase Inhibitors as Radiosensitizers for Proton and Light Ion Radiotherapy. Frontiers in Oncology 11.
Crossref
Xiuhong Wei, Bolian Xiao, Liying Wang, Lanlan Zang & Fengyuan Che. (2021) Potential new targets and drugs related to histone modifications in glioma treatment. Bioorganic Chemistry 112, pages 104942.
Crossref
Beatrice Ferrari, Elisa Roda, Erica Cecilia Priori, Fabrizio De Luca, Angelica Facoetti, Mauro Ravera, Federico Brandalise, Carlo Alessandro Locatelli, Paola Rossi & Maria Grazia Bottone. (2021) A New Platinum-Based Prodrug Candidate for Chemotherapy and Its Synergistic Effect With Hadrontherapy: Novel Strategy to Treat Glioblastoma. Frontiers in Neuroscience 15.
Crossref
Changhoon Choi, Ga Haeng Lee, Arang Son, Gyu Sang Yoo, Jeong Il Yu & Hee Chul Park. (2021) Downregulation of Mcl-1 by Panobinostat Potentiates Proton Beam Therapy in Hepatocellular Carcinoma Cells. Cells 10:3, pages 554.
Crossref
Shuhua Zheng & Wensi Tao. (2020) Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs. Frontiers in Oncology 10.
Crossref
Maja Svetličič, Anton Bomhard, Christoph Sterr, Fabian Brückner, Magdalena Płódowska, Halina Lisowska & Lovisa Lundholm. (2020) Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells. Cells 9:5, pages 1165.
Crossref
Lin Kong & JiadeJ Lu. (2020) Particle radiation therapy in the management of adult high-grade glioma: A narrative review. Glioma 3:4, pages 149.
Crossref
Lin Kong, Jing Gao, Jiyi Hu, Rong Lu, Jing Yang, Xianxin Qiu, Weixu Hu & Jiade J. Lu. (2019) Carbon ion radiotherapy boost in the treatment of glioblastoma: a randomized phase I/III clinical trial. Cancer Communications 39:1, pages 5.
Crossref
Younghyun Lee & Ryuichi Okayasu. (2018) Strategies to Enhance Radiosensitivity to Heavy Ion Radiation Therapy. International Journal of Particle Therapy 5:1, pages 114-121.
Crossref
Ariungerel Gerelchuluun, Junko Maeda, Eri Manabe, Colleen Brents, Takeji Sakae, Akira Fujimori, David Chen, Koji Tsuboi & Takamitsu Kato. (2018) Histone Deacetylase Inhibitor Induced Radiation Sensitization Effects on Human Cancer Cells after Photon and Hadron Radiation Exposure. International Journal of Molecular Sciences 19:2, pages 496.
Crossref
Pallavi Srivastava, Asitikantha Sarma & Chandra Mohini Chaturvedi. (2018) Targeting DNA repair with PNKP inhibition sensitizes radioresistant prostate cancer cells to high LET radiation. PLOS ONE 13:1, pages e0190516.
Crossref
Luciana O. Almeida, Douglas M. Guimarães, Manoela D. Martins, Marco A.T. Martins, Kristy A. Warner, Jacques E. Nör, Rogerio M. Castilho & Cristiane H. Squarize. (2017) Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence. Stem Cell Research 21, pages 94-105.
Crossref
Dong Hoon Lee, Hyun-Wook Ryu, Hye-Rim Won & So Hee Kwon. (2017) Advances in epigenetic glioblastoma therapy. Oncotarget 8:11, pages 18577-18589.
Crossref
Katsuyo SaitoTomoo FunayamaYuichiro YokotaTakashi Murakami & Yasuhiko Kobayashi. (2017) Histone Deacetylase Inhibitors Sensitize Murine B16F10 Melanoma Cells to Carbon Ion Irradiation by Inducing G1 Phase Arrest. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 40:6, pages 844-851.
Crossref
Che-Chia Hsu, Wen-Chang Chang, Tsung-I Hsu, Jr-Jiun Liu, Shiu-Hwa Yeh, Jia-Yi Wang, Jing-Ping Liou, Chiung-Yuan Ko, Kwang-Yu Chang & Jian-Ying Chuang. (2016) Suberoylanilide hydroxamic acid represses glioma stem-like cells. Journal of Biomedical Science 23:1.
Crossref
Zhiqiang Zhang, Yunmin Wang, Jiehan Chen, Qijia Tan, Caijun Xie, Cong Li, Wengang Zhan & Mei Wang. (2016) Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity. Cancer Chemotherapy and Pharmacology 78:6, pages 1289-1296.
Crossref
Ranjit S. Bindra & Suzanne L. Wolden. (2015) Advances in Radiation Therapy in Pediatric Neuro-oncology. Journal of Child Neurology 31:4, pages 506-516.
Crossref
Patrick Maier, Linda Hartmann, Frederik Wenz & Carsten Herskind. (2016) Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization. International Journal of Molecular Sciences 17:1, pages 102.
Crossref
Rosaria Benedetti, Mariarosaria Conte, Concetta Iside & Lucia Altucci. (2015) Epigenetic-based therapy: From single- to multi-target approaches. The International Journal of Biochemistry & Cell Biology 69, pages 121-131.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.