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International Journal of Radiation Biology Volume 91, 2015 - Issue 7
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DTPA DI-ETHYL ESTER FOR DECORPORATION OF 241 AM

Orally administered DTPA di-ethyl ester for decorporation of 241Am in dogs: Assessment of safety and efficacy in an inhalation-contamination model

James E. HuckleUniversity of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, Chapel Hill, NC
,
Matthew P. SadgroveUniversity of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, Chapel Hill, NC
,
Erik PacyniakUniversity of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, Chapel Hill, NC
,
Marina G. D. LeedUniversity of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, Chapel Hill, NC
,
Waylon M. WeberLovelace Respiratory Research Institute, Albuquerque, NM
,
Melanie Doyle-EiseleLovelace Respiratory Research Institute, Albuquerque, NM
,
Raymond A. GuilmetteLovelace Respiratory Research Institute, Albuquerque, NM
,
Bushra J. AghaAgha Consulting, Chapel Hill, NC
,
Robert L. SusickSusick Consulting, Chapel Hill, NC, USA
,
Russell J. MumperUniversity of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, Chapel Hill, NC
&
Michael JayUniversity of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, Chapel Hill, NCCorrespondence[email protected]
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Pages 568-575 | Received 22 Jul 2014, Accepted 17 Mar 2015, Published online: 21 May 2015

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Angela M. Groves & Jacqueline P. Williams. (2019) Saving normal tissues – a goal for the ages. International Journal of Radiation Biology 95:7, pages 920-935.
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Anissa Tazrart, Marie-Alexandrine Bolzinger, Sylvie Coudert, Stephanie Lamart, Brian W. Miller, Jaime F. Angulo, Stéphanie Briançon & Nina M. Griffiths. (2017) Skin absorption of actinides: influence of solvents or chelates on skin penetration ex vivo. International Journal of Radiation Biology 93:6, pages 607-616.
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Articles from other publishers (10)

Thomas A. Winters, David R. Cassatt, Jenna R. Harrison-Peters, Brynn A. Hollingsworth, Carmen I. Rios, Merriline M. Satyamitra, Lanyn P. Taliaferro & Andrea L. DiCarlo. (2023) Considerations of Medical Preparedness to Assess and Treat Various Populations During a Radiation Public Health Emergency. Radiation Research 199:3.
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Lanyn P. Taliaferro, Andrea L. DiCarlo & Merriline M. Satyamitra. (2022) NIH Policies and Regulatory Pathways for the Advancement of Radiation Medical Countermeasures and Biodosimetry Tools to U.S. FDA Licensure. Radiation Research 197:5.
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Merriline M. SatyamitraZulmarie Perez-HortaAndrea L. DiCarloDavid R. CassattCarmen I. RiosPaul W. PriceLanyn P. Taliaferro. (2022) NIH Policies and Regulatory Pathways to U.S. FDA licensure: Strategies to Inform Advancement of Radiation Medical Countermeasures and Biodosimetry Devices. Radiation Research 197:5.
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A. N. Grebenyuk & V. D. Gladkikh. (2020) Modern Condition and Prospects for the Development of Medicines towards Prevention and Early Treatment of Radiation Damage. Biology Bulletin 46:11, pages 1540-1555.
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Carla Coste Sanchez, Arjun Kalra, Tonglei Li & Michael Jay. (2018) Solid-State Characterization of Three Polymorphs of an Orally Available Analog of Diethylenetriaminepentaacetic Acid. AAPS PharmSciTech 20:1.
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Diane RiccobonoMarco ValenteMichel DrouetFranck CalamaiAmandine Abriat. (2018) French Policies for Victim Management During Mass Radiological Accidents/Attacks. Health Physics 115:1, pages 179-184.
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A. Tazrart, M.A. Bolzinger, A. Moureau, T. Molina, S. Coudert, J.F. Angulo, S. Briancon & N.M. Griffiths. (2017) Penetration and decontamination of americium-241 ex vivo using fresh and frozen pig skin. Chemico-Biological Interactions 267, pages 40-47.
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John P. Prybylski, Richard C. Semelka & Michael Jay. (2016) Can gadolinium be re-chelated in vivo? Considerations from decorporation therapy. Magnetic Resonance Imaging 34:10, pages 1391-1393.
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Rebecca J. Abergel. 2016. Metal Chelation in Medicine. Metal Chelation in Medicine 183 212 .
J. Fu, M. Sadgrove, L. Marson & M. Jay. (2016) Biotransformation Capacity of Carboxylesterase in Skin and Keratinocytes for the Penta-Ethyl Ester Prodrug of DTPA. Drug Metabolism and Disposition 44:8, pages 1313-1318.
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