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International Journal of Radiation Biology Volume 91, 2015 - Issue 10
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ORIGINAL ARTICLE

High dose rate and flattening filter free irradiation can be safely implemented in clinical practice

Ludwig DuboisDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the NetherlandsCorrespondence[email protected]
,
Rianne BiemansDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Brigitte ReniersDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Geert BosmansDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Daniela TraniDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Mark PodestaDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Robert KollaardDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Kasper ma RouschopDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Jan TheysDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Marc VooijsDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Martin PruschyDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland
,
Frank VerhaegenDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
&
Philippe LambinDepartment of Radiation Oncology (MAASTRO), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands
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Pages 778-785 | Received 21 Nov 2014, Accepted 24 Jun 2015, Published online: 28 Aug 2015

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Serhat Aras, İ̇hsan Oğuz Tanzer, Seyhan Karaçavuş, Neslihan Sayir, Esra Erdem, Fatih Hacımustafaoğlu, Ceren Ezgi Erdoğan, Tansel Sapmaz, Türkan İkizceli, Halime Hanım Pençe, Kürşad Nuri Baydili & Tolga Katmer. (2023) Effect of melatonin on low and high dose radiotherapy induced thyroid injury. Biotechnic & Histochemistry 98:5, pages 346-352.
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Junko Takahashi, Masaki Misawa & Hitoshi Iwahashi. (2016) Combined treatment with X-ray irradiation and 5-aminolevulinic acid elicits better transcriptomic response of cell cycle-related factors than X-ray irradiation alone. International Journal of Radiation Biology 92:12, pages 774-789.
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Articles from other publishers (7)

Valentina Dini, Giuseppe Esposito, Andrea Sacconi, Marco D’Andrea, Maria Antonella Tabocchini, Pasquale Anello, Lucia Ricci-Vitiani, Mariachiara Buccarelli, Roberto Pallini & Lidia Strigari. (2023) Effectiveness of Flattening-Filter-Free versus Flattened Beams in V79 and Glioblastoma Patient-Derived Stem-like Cells. International Journal of Molecular Sciences 24:2, pages 1107.
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P Kouris, A Moutsatsos, E P Pappas, I Beli, P Pantelakos, P Karaiskos & E Pantelis. (2021) Assessing the dose rate delivery of helical TomoTherapy prostate and head & neck treatments. Biomedical Physics & Engineering Express 8:1, pages 015005.
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Mustapha Assalmi & El Yamani Diaf. (2022) Monte Carlo Simulation of Surface Dose and Dose Rate in 6MV-FFF Beams. Moscow University Physics Bulletin 76:S1, pages S36-S51.
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Serhat Aras. (2021) Effect of Flattening Filter and Flattening Filter Free beams on radiotherapy-induced peripheral blood cell damage. Radiation Physics and Chemistry 182, pages 109383.
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Daisuke Kawahara, Hisashi Nakano, Akito Saito, Shuichi Ozawa & Yasushi Nagata. (2020) Dose compensation based on biological effectiveness due to interruption time for photon radiation therapy. The British Journal of Radiology 93:1111, pages 20200125.
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Philippe Lambin, Relinde I.Y. Lieverse, Franziska Eckert, Damiënne Marcus, Cary Oberije, Alexander M.A. van der Wiel, Chandan Guha, Ludwig J. Dubois & Joseph O. Deasy. (2020) Lymphocyte-Sparing Radiotherapy: The Rationale for Protecting Lymphocyte-rich Organs When Combining Radiotherapy With Immunotherapy. Seminars in Radiation Oncology 30:2, pages 187-193.
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Julia Torres del Río, Cristina Forastero, Miguel Moreno-Torres, María Molina-Matas, Ana M. Martínez-Felipe, Álvaro Moreno, Jesús J. López-Peñalver & Damián Guirado. (2019) Use of radiochromic film dosimetry in radiobiology experiments. Radiation Physics and Chemistry 156, pages 169-173.
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