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International Journal of Food Sciences and Nutrition Volume 61, 2010 - Issue 8
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Metabolites of amygdalin under simulated human digestive fluids

Soon-Mi Shim Department of Food Science and Technology, Ewha Womans University, Seoul, South Korea
&
Hoonjeong Kwon Department of Food & Nutrition, Seoul National University, Gwanak-gu, Seoul, South KoreaCorrespondence[email protected]
Pages 770-779 | Received 03 Mar 2010, Accepted 22 Mar 2010, Published online: 09 Jun 2010

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Patrik Cmorej, Petr Bruthans, Jaroslav Halamka, Irena Voriskova & David Peran. (2022) Life-Threatening Cyanide Intoxication after Ingestion of Amygdalin in Prehospital Care. Prehospital Emergency Care 26:3, pages 455-458.
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Articles from other publishers (32)

Ahmed Mohammed Alwan & Jalil Tavakol Afshari. (2023) Investigating the Protective Role of Rhodanese Enzyme against Cyanide, the Cytotoxic by-product of Amygdalin, in HDF and L929 Cell Lines. Letters in Drug Design & Discovery 20:9, pages 1295-1307.
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Halfane Lehmane, Arnaud N. Kohonou, Atchadé Pascal Tchogou, Radiate Ba, Durand Dah-Nouvlessounon, Oscar Didagbé, Haziz Sina, Maximin Senou, Adolphe Adjanohoun & Lamine Baba-Moussa. (2023) Antioxidant, Anti-Inflammatory, and Anti-Cancer Properties of Amygdalin Extracted from Three Cassava Varieties Cultivated in Benin. Molecules 28:11, pages 4548.
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Mohamed Ali El-Desouky, Abdelgawad Ali Fahmi & Karima Mahmoud Nasraldin. (2023) The Postulated Mechanism of Action of Amygdalin (Vitamin B17) on Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry 23:8, pages 894-899.
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Ahmed Mohammed Alwan, Dinesh Rokaya, Goma Kathayat & Jalil Tavakol Afshari. (2023) Onco-immunity and therapeutic application of amygdalin: A review. Journal of Oral Biology and Craniofacial Research 13:2, pages 155-163.
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Guoqin Zhang, Meiqi Liu, Zicheng Ma, Meng Wang, Lili Sun, Yanan Liu & Xiaoliang Ren. (2023) Analysis of Bitter Almonds and Processed Products Based on HPLC‐Fingerprints and Chemometry. Chemistry & Biodiversity 20:3.
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Marianna Giancaterino, Thomas Fauster, Anna Krottenthaler & Henry Jäger. (2023) Effect of pulsed electric field pre-treatment on the debittering process of cherry kernels. Innovative Food Science & Emerging Technologies 83, pages 103234.
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Vadivelan RamachandranKirankumar Rapindra HosalliInbakumar VijayakumarLalithkumar ManiRuchi TiwariGaurav Tiwari. (2022) A review on antitumor action of amygdalin on various types of cancers. Research Journal of Pharmacy and Technology, pages 5373-5380.
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Qiuyu Wen, Shen Yu, Shanshan Wang, Yan Qin, Quan Xia, Sheng Wang, Guanjun Chen, Chenlin Shen & Shuai Song. (2022) Impact of intestinal microbiota on metabolic toxicity and potential detoxification of amygdalin. Frontiers in Microbiology 13.
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Alexander V. Sirotkin & Adriana Kolesarova. 2022. Environmental Contaminants and Medicinal Plants Action on Female Reproduction. Environmental Contaminants and Medicinal Plants Action on Female Reproduction 245 399 .
Daniela Figurová, Katarína Tokárová, Hana Greifová, Nikola Knížatová, Adriana Kolesárová & Norbert Lukáč. (2021) Inflammation, It’s Regulation and Antiphlogistic Effect of the Cyanogenic Glycoside Amygdalin. Molecules 26:19, pages 5972.
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Adriana Kolesarova, Simona Baldovska & Shubhadeep Roychoudhury. (2021) The Multiple Actions of Amygdalin on Cellular Processes with an Emphasis on Female Reproduction. Pharmaceuticals 14:9, pages 881.
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Pascual Garcia-Perez, Jianbo Xiao, Paulo E. S. Munekata, Jose M. Lorenzo, Francisco J. Barba, Muhammad Shahid Riaz Rajoka, Lillian Barros, Rafael Mascoloti Sprea, Joana S. Amaral, Miguel A. Prieto & Jesus Simal-Gandara. (2021) Revalorization of Almond By-Products for the Design of Novel Functional Foods: An Updated Review. Foods 10:8, pages 1823.
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Ewa Jaszczak-Wilke, Żaneta Polkowska, Marek Koprowski, Krzysztof Owsianik, Alyson E. Mitchell & Piotr Bałczewski. (2021) Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds. Molecules 26:8, pages 2253.
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Yan He, Weiwei Su, Xiang He, Taobin Chen, Xuan Zeng, Zenghao Yan, Weijian Zhang, Wei Yang, Jianmin Guo & Hao Wu. (2021) Pharmacokinetics and biotransformation investigation in beagle dog of active compounds from naoxintong capsule. Biomedicine & Pharmacotherapy 133, pages 110940.
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Hyun Woo Choi & Hyun-Seok Kim. (2020) Amygdalin and Quality Characteristics of Maesil Chung by Different Cultivars of Maesil (<i>Prunus mume</i>). Food Engineering Progress 24:4, pages 285-291.
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Yongheng Zhong, Tao Xu, Qi Chen, Kaimian Li, Zhenwen Zhang, Huaxin Song, Mengmeng Wang, Xiaodan Wu & Baiyi Lu. (2020) Development and validation of eight cyanogenic glucosides via ultra-high-performance liquid chromatography-tandem mass spectrometry in agri-food. Food Chemistry 331, pages 127305.
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Vasil Tsanov & Hristo Tsanov. (2020) Theoretical Analysis for the Safe Form and Dosage of Amygdalin Product. Anti-Cancer Agents in Medicinal Chemistry 20:7, pages 897-908.
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Xiao-Yan He, Li-Juan Wu, Wen-Xiang Wang, Pei-Jun Xie, Yun-Hui Chen & Fei Wang. (2020) Amygdalin - A pharmacological and toxicological review. Journal of Ethnopharmacology 254, pages 112717.
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Jeffrey D. White. 2020. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 500 511.e4 .
Yan He, Weiwei Su, Taobin Chen, Xuan Zeng, Zenghao Yan, Jianmin Guo, Wei Yang & Hao Wu. (2019) Identification of prototype compounds and derived metabolites of naoxintong capsule in beagle dog urine and feces by UFLC-Q-TOF-MS/MS. Journal of Pharmaceutical and Biomedical Analysis 176, pages 112806.
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Eun-Hye Choi, Seon-Bong Lee, Da-Yeon Lee, Goon-Tae Kim, Soon-Mi Shim & Tae-Sik Park. (2019) Increased Intestinal Absorption of Vitamin U in Steamed Graviola Leaf Extract Activates Nicotine Detoxification. Nutrients 11:6, pages 1334.
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Jiamin Shi, Qianqian Chen, Meng Xu, Qing Xia, Tiansheng Zheng, Junliang Teng, Ming Li & Lihong Fan. (2019) Recent updates and future perspectives about amygdalin as a potential anticancer agent: A review. Cancer Medicine 8:6, pages 3004-3011.
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Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Christiane Vleminckx, Heather Wallace, Diane Benford, Leon Brimer, Francesca Romana Mancini, Manfred Metzler, Barbara Viviani, Andrea Altieri, Davide Arcella, Hans Steinkellner & Tanja Schwerdtle. (2019) Evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels. EFSA Journal 17:4.
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Ewa Jaszczak, Krystyna Kozioł, Bogumiła Kiełbratowska & Żaneta Polkowska. (2019) Application of ion chromatography with pulsed amperometric detection for the determination of trace cyanide in biological samples, including breast milk. Journal of Chromatography B 1110-1111, pages 36-42.
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Peter Cressey & John Reeve. (2019) Metabolism of cyanogenic glycosides: A review. Food and Chemical Toxicology 125, pages 225-232.
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Mi-Ran Go, Hyeon-Jin Kim, Jin Yu & Soo-Jin Choi. (2018) Toxicity and Toxicokinetics of Amygdalin in Maesil ( Prunus mume ) Syrup: Protective Effect of Maesil against Amygdalin Toxicity . Journal of Agricultural and Food Chemistry 66:43, pages 11432-11440.
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Chao Liu, Xia Li, Honggai Yang, Xinhui Mao, Juan Wang & Wenyuan Gao. (2017) Effect of Natural β-Glucosidase Inhibitors in Reducing Toxicity of Amygdalin in Persicae Semen. Phytotherapy Research 31:5, pages 771-777.
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Roman A. Blaheta, Karen Nelson, Axel Haferkamp & Eva Juengel. (2016) Amygdalin, quackery or cure?. Phytomedicine 23:4, pages 367-376.
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Stefania Milazzo, Markus Horneber & Edzard Ernst. (2015) Laetrile treatment for cancer. Cochrane Database of Systematic Reviews 2018:7.
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Jeffrey D. White. 2014. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 519 529.e4 .
SOON-MI SHIM. (2012) CHANGES IN PROFILING OF PHENOLIC COMPOUNDS, ANTIOXIDATIVE EFFECT AND TOTAL PHENOLIC CONTENT IN SMILAX CHINA UNDER IN VITRO PHYSIOLOGICAL CONDITION . Journal of Food Biochemistry 36:6, pages 748-755.
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Stefania Milazzo, Edzard Ernst, Stephane Lejeune, Katja Boehm & Markus Horneber. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.

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