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In Vitro and Animal Studies

Identification of ACE-inhibitory peptides from Phaseolus vulgaris after in vitro gastrointestinal digestion

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Pages 774-782 | Received 15 May 2015, Accepted 12 Aug 2015, Published online: 23 Sep 2015

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Jyoti Tripathi, Sumit Gupta & Satyendra Gautam. (2023) Alpha-cadinol as a potential ACE-inhibitory volatile compound identified from Phaseolus vulgaris L. through in vitro and in silico analysis. Journal of Biomolecular Structure and Dynamics 41:9, pages 3847-3861.
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Chaudhari Hiralben Mansinhbhai, Amar Sakure, Zhenbin Liu, Ruchika Maurya, Sujit Das, Bethsheba Basaiawmoit, Mahendra Bishnoi, Kanthi Kiran Kondepudi, Srichandan Padhi, Amit Kumar Rai, Birendra K. Mishra & Subrota Hati. (2023) Anti-Inflammatory, ACE Inhibitory, Antioxidative Activities and Release of Novel Antihypertensive and Antioxidative Peptides from Whey Protein Hydrolysate with Molecular Interactions. Journal of the American Nutrition Association 42:4, pages 371-385.
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Samir Mahgoub, Mahmoud Alagawany, Maha Nader, Safaa M. Omar, Mohamed E. Abd El-Hack, Ayman Swelum, Shaaban S. Elnesr, Asmaa F. Khafaga, Ayman E. Taha, Mayada R. Farag, Ruchi Tiwari, Gopi Marappan, Ashraf S. El-Sayed, Shailesh K. Patel, Mamta Pathak, Izabela Michalak, Etab S. Al-Ghamdi & Kuldeep Dhama. (2023) Recent Development in Bioactive Peptides from Plant and Animal Products and Their Impact on the Human Health. Food Reviews International 39:1, pages 511-536.
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Domancar Orona-Tamayo, María Elena Valverde & Octavio Paredes-López. (2019) Bioactive peptides from selected latin american food crops – A nutraceutical and molecular approach. Critical Reviews in Food Science and Nutrition 59:12, pages 1949-1975.
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Jessica L Correa, José Edgar Zapata & Blanca Hernández-Ledesma. (2022) Release of Bioactive Peptides from Erythrina edulis (Chachafruto) Proteins under Simulated Gastrointestinal Digestion. Nutrients 14:24, pages 5256.
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Juliana Vila Verde Ribeiro, Daniel Graziani, Jhulle Horrane Moreira Carvalho, Michelle Mendanha Mendonça, Lara Marques Naves, Helton Freires Oliveira, Hericles Mesquita Campos, Maria Clorinda Soares Fioravanti, Lilian Fernanda Pacheco, Patricia Maria Ferreira, Gustavo Rodrigues Pedrino, Paulo César Ghedini, Kátia Flávia Fernandes, Karla de Aleluia Batista & Carlos Henrique Xavier. (2022) A peptide fraction from hardened common beans (Phaseolus vulgaris) induces endothelium-dependent antihypertensive and renal effects in hypertensive rats. Current Research in Food Science, pages 100410.
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Divyang Solanki, Amar Sakure, Sangeeta Prakash & Subrota Hati. (2022) Characterization of Angiotensin I-Converting Enzyme (ACE) inhibitory peptides produced in fermented camel milk (Indian breed) by Lactobacillus acidophilus NCDC-15. Journal of Food Science and Technology 59:9, pages 3567-3577.
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Gaurav Kumar Panchal, Sujit Das, Amar Sakure, Brij Pal Singh & Subrota Hati. (2021) Production and characterization of antioxidative peptides during lactic fermentation of goat milk. Journal of Food Processing and Preservation 45:12.
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Ahmed S. Gouda, Fatima G. Adbelruhman, Hamedah Sabbah Alenezi & Bruno Mégarbane. (2021) Theoretical benefits of yogurt-derived bioactive peptides and probiotics in COVID-19 patients – A narrative review and hypotheses. Saudi Journal of Biological Sciences 28:10, pages 5897-5905.
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Bhoomika Patel, Supriya Sharma, Nisha Nair, Jaseela Majeed, Ramesh K. Goyal & Mahaveer Dhobi. (2021) Therapeutic opportunities of edible antiviral plants for COVID-19. Molecular and Cellular Biochemistry 476:6, pages 2345-2364.
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Lineth Juliana Vega-Rojas, Ivan Luzardo-Ocampo, Juan Mosqueda, Dulce María Palmerín-Carreño, Antonio Escobedo-Reyes, Alejandro Blanco-Labra, Konisgmar Escobar-García & Teresa García-Gasca. (2021) Bioaccessibility and In Vitro Intestinal Permeability of a Recombinant Lectin from Tepary Bean (Phaseolus acutifolius) Using the Everted Intestine Assay. International Journal of Molecular Sciences 22:3, pages 1049.
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D. Graziani, J.V.V. Ribeiro, V.S. Cruz, R.M. Gomes, E.G. Araújo, A.C.M. Santos Júnior, H.C.M. Tomaz, C.H. Castro, W. Fontes, K.A. Batista, K.F. Fernandes & C.H. Xavier. (2021) Oxidonitrergic and antioxidant effects of a low molecular weight peptide fraction from hardened bean (Phaseolus vulgaris) on endothelium. Brazilian Journal of Medical and Biological Research 54:6.
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Dhvany Kinariwala, Gauravkumar Panchal, Amar Sakure & Subrota Hati. (2019) Exploring the Potentiality of Lactobacillus Cultures on the Production of Milk-Derived Bioactive Peptides with Antidiabetic Activity. International Journal of Peptide Research and Therapeutics 26:3, pages 1613-1627.
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Heena Parmar, Subrota Hati, Gauravkumar Panchal & Amar A. Sakure. (2019) Purification and Production of Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Bioactive Peptides Derived from Fermented Goat Milk. International Journal of Peptide Research and Therapeutics 26:2, pages 997-1011.
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Gauravkumar Panchal, Subrota Hati & Amar Sakure. (2020) Characterization and production of novel antioxidative peptides derived from fermented goat milk by L. fermentum. LWT 119, pages 108887.
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Connie Schisano, Viviana Narciso, Maria Maisto, Giuseppe Annunziata, Paolo Grieco, Eduardo Maria Sommella, Gian Carlo Tenore & Ettore Novellino. (2019) In vitro effects of protein fractions from Controne beans (Phaseolus vulgaris L. ecotype Controne) on intestinal permeability, ACE and α-amylase activities. European Food Research and Technology 245:10, pages 2311-2322.
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Alberto R. Corrochano, Anita Ferraretto, Elena Arranz, Milda Stuknytė, Michela Bottani, Paula M. O'Connor, Phil M. Kelly, Ivano De Noni, Vitaly Buckin & Linda Giblin. (2019) Bovine whey peptides transit the intestinal barrier to reduce oxidative stress in muscle cells. Food Chemistry 288, pages 306-314.
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Heena Parmar, Subrota Hati & Amar Sakure. (2017) In Vitro and In Silico Analysis of Novel ACE-Inhibitory Bioactive Peptides Derived from Fermented Goat Milk. International Journal of Peptide Research and Therapeutics 24:3, pages 441-453.
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Subrota Hati, Nikita Patel, Amar Sakure & Surajit Mandal. (2017) Influence of Whey Protein Concentrate on the Production of Antibacterial Peptides Derived from Fermented Milk by Lactic Acid Bacteria. International Journal of Peptide Research and Therapeutics 24:1, pages 87-98.
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Chunyan Qi, Rong Zhang, Fuzhi Liu, Tong Zheng & Wenjuan Wu. (2018) Molecular mechanism of interactions between inhibitory tripeptide GEF and angiotensin-converting enzyme in aqueous solutions by molecular dynamic simulations. Journal of Molecular Liquids 249, pages 389-396.
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Divyangkumar Solanki, Subrota Hati & Amar Sakure. (2017) In Silico and In vitro Analysis of Novel Angiotensin I-Converting Enzyme (ACE) inhibitory Bioactive Peptides Derived from Fermented Camel Milk (Camelus dromedarius). International Journal of Peptide Research and Therapeutics 23:4, pages 441-459.
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Davide Tagliazucchi, Sherif Shamsia, Ahmed Helal & Angela Conte. (2017) Angiotensin-converting enzyme inhibitory peptides from goats' milk released by in vitro gastro-intestinal digestion. International Dairy Journal 71, pages 6-16.
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Carlo G. Rizzello, Davide Tagliazucchi, Elena Babini, Giuseppina Sefora Rutella, Danielle L. Taneyo Saa & Andrea Gianotti. (2016) Bioactive peptides from vegetable food matrices: Research trends and novel biotechnologies for synthesis and recovery. Journal of Functional Foods 27, pages 549-569.
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Giuseppina Sefora Rutella, Lisa Solieri, Serena Martini & Davide Tagliazucchi. (2016) Release of the Antihypertensive Tripeptides Valine-Proline-Proline and Isoleucine-Proline-Proline from Bovine Milk Caseins during in Vitro Gastrointestinal Digestion. Journal of Agricultural and Food Chemistry 64:45, pages 8509-8515.
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Davide Tagliazucchi, Ahmed Helal, Elena Verzelloni & Angela Conte. (2016) Bovine milk antioxidant properties: effect of in vitro digestion and identification of antioxidant compounds. Dairy Science & Technology 96:5, pages 657-676.
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Davide Tagliazucchi, Sherif Shamsia & Angela Conte. (2016) Release of angiotensin converting enzyme-inhibitory peptides during in vitro gastro-intestinal digestion of camel milk. International Dairy Journal 56, pages 119-128.
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Diego A. Luna-Vital, Katie Liang, Elvira González de Mejía & Guadalupe Loarca-Piña. (2016) Dietary peptides from the non-digestible fraction of Phaseolus vulgaris L. decrease angiotensin II-dependent proliferation in HCT116 human colorectal cancer cells through the blockade of the renin–angiotensin system. Food & Function 7:5, pages 2409-2419.
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