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Molecular Membrane Biology Volume 31, 2014 - Issue 7-8
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Research Article

Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4

Justin C. DemeDepartment of Microbiology and Immunology, McGill University MontrealCanada
,
Mark A. HancockMcGill University Surface Plasmon Resonance (SPR) Facility MontrealCanada
,
Xiaobing XiaStructural Genomics Consortium, University of Oxford OxfordUK
,
Chitra A. ShintreStructural Genomics Consortium, University of Oxford OxfordUK
,
Maria PlesaDepartment of Microbiology and Immunology, McGill University MontrealCanada;Department of Human Genetics, McGill University MontrealCanada
,
Jaeseung C. KimDepartment of Microbiology and Immunology, McGill University MontrealCanada;Department of Human Genetics, McGill University MontrealCanada
,
Elisabeth P. CarpenterStructural Genomics Consortium, University of Oxford OxfordUK
,
David S. RosenblattDepartment of Human Genetics, McGill University MontrealCanada
&
James W. CoultonDepartment of Microbiology and Immunology, McGill University MontrealCanadaCorrespondence[email protected]
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Pages 250-261 | Received 05 Aug 2014, Accepted 08 Nov 2014, Published online: 23 Dec 2014

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Jean-Louis Guéant, Rosa-Maria Guéant-Rodriguez, Viola J. Kosgei & David Coelho. (2022) Causes and consequences of impaired methionine synthase activity in acquired and inherited disorders of vitamin B12 metabolism. Critical Reviews in Biochemistry and Molecular Biology 57:2, pages 133-155.
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Areti-Maria Vasilogianni, Sarah Alrubia, Eman El-Khateeb, Zubida M. Al-Majdoub, Narciso Couto, Brahim Achour, Amin Rostami-Hodjegan & Jill Barber. (2024) Complementarity of two proteomic data analysis tools in the identification of drug-metabolising enzymes and transporters in human liver. Molecular Omics.
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Amer Alam & Kaspar P. Locher. (2023) Structure and Mechanism of Human ABC Transporters. Annual Review of Biophysics 52:1, pages 275-300.
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Thomas J. McCorvie, Douglas Ferreira, Wyatt W. Yue & D. Sean Froese. (2023) The complex machinery of human cobalamin metabolism. Journal of Inherited Metabolic Disease 46:3, pages 406-420.
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Haining YangMian LiLiang ZouHui ZouYan ZhaoYazhou CuiJinxiang Han. (2023) A regionally adapted HRM-based technique to screen MMACHC carriers for methylmalonic acidemia with homocystinuria in Shandong Province, China. Intractable & Rare Diseases Research 12:1, pages 29-34.
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Akari Miyamoto, Takashi Yamanaka, Satomi Suzuki, Kota Kunii, Kenichiro Kurono, Akira Yoshimi, Masafumi Hidaka, Satoshi Ogasawara, Kei Nanatani & Keietsu Abe. (2022) Oligomeric state of the aspartate:alanine transporter from Tetragenococcus halophilus . The Journal of Biochemistry 172:4, pages 217-224.
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Kosuke Kawaguchi & Tsuneo Imanaka. (2022) Substrate Specificity and the Direction of Transport in the ABC Transporters ABCD1–3 and ABCD4. Chemical and Pharmaceutical Bulletin 70:8, pages 533-539.
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Luciana Hannibal & Donald W. Jacobsen. 2022. Vitamin B12. Vitamin B12 275 298 .
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Sönke Rudnik & Markus Damme. (2020) The lysosomal membrane—export of metabolites and beyond. The FEBS Journal 288:14, pages 4168-4182.
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Chiao-Yin Sun, Shin C. Chang, Hsiu-Po Wang, Yu-Jung Lee, Kuei-Hsiang Pan, Chieh-Liang Lin, Yu-Ting Hsieh, Yng-Cun Ta, Yau-Hung Chen & Ming-Fu Chang. (2021) LMBD1 protein participates in cell mitosis by regulating microtubule assembly. Biochemical Journal 478:12, pages 2321-2337.
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Nishitha R. Pillai, Dana Miller, Elizabeth I. Pierpont, Susan A. Berry & Anjali Aggarwal. (2021) Cobalamin J disease detected on newborn screening: Novel variant and normal neurodevelopmental course. American Journal of Medical Genetics Part A 185:6, pages 1870-1874.
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Katsuki Kitai, Kosuke Kawaguchi, Takenori Tomohiro, Masashi Morita, Takanori So & Tsuneo Imanaka. (2021) The lysosomal protein ABCD4 can transport vitamin B12 across liposomal membranes in vitro. Journal of Biological Chemistry 296, pages 100654.
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Gergely Szakacs & Rupert Abele. (2020) An inventory of lysosomal ABC transporters. FEBS Letters 594:23, pages 3965-3985.
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Aatish Mahajan, Divika Sapehia, Shilpa Thakur, Palani Selvam Mohanraj, Rashmi Bagga & Jyotdeep Kaur. (2019) Effect of imbalance in folate and vitamin B12 in maternal/parental diet on global methylation and regulatory miRNAs. Scientific Reports 9:1.
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Young Min Choi, Yong-Il Kim, Jung-Hwa Choi, Sushil Bhandari, In-Koo Nam, KwangHeum Hong, SeongAe Kwak, Hong-Seob So, Do-Sim Park, Cheol-Hee Kim, Tae-Young Choi & Seong-Kyu Choe. (2019) Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia. Biochemical and Biophysical Research Communications 514:4, pages 1264-1269.
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Xiaodong Liu. 2019. Drug Transporters in Drug Disposition, Effects and Toxicity. Drug Transporters in Drug Disposition, Effects and Toxicity 13 100 .
S. Surendran, A. Adaikalakoteswari, P. Saravanan, I. A. Shatwaan, J. A. Lovegrove & K. S. Vimaleswaran. (2018) An update on vitamin B12-related gene polymorphisms and B12 status. Genes & Nutrition 13:1.
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Han Feng, Shijie Zhang, Jennifer Man-Fan Wan, Lifeng Gui, Mengcheng Ruan, Na Li, Hongyu Zhang, Zhiguo Liu & Hualin Wang. (2018) Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice. Carbohydrate Polymers 200, pages 144-153.
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Kallol Gupta, Jingwen Li, Idlir Liko, Joseph Gault, Cherine Bechara, Di Wu, Jonathan T S Hopper, Kevin Giles, Justin L P Benesch & Carol V Robinson. (2018) Identifying key membrane protein lipid interactions using mass spectrometry. Nature Protocols 13:5, pages 1106-1120.
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Hamid M. Said & Ebba Nexo. 2018. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 1201 1248 .
Megan K. McDonald, Julie-Anne Fritz, Dongxin Jia, Deborah Scheuchner, Floyd F. Snyder, Avalyn Stanislaus, Jared Curle, Liang Li, Sally P. Stabler, Robert H. Allen, Paul E. Mains & Roy A. Gravel. (2017) Identification of ABC transporters acting in vitamin B 12 metabolism in Caenorhabditis elegans. Molecular Genetics and Metabolism 122:4, pages 160-171.
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Victoria Fettelschoss, Patricie Burda, Corinne Sagné, David Coelho, Corinne De Laet, Seraina Lutz, Terttu Suormala, Brian Fowler, Nicolas Pietrancosta, Bruno Gasnier, Beat Bornhauser, D.Sean Froese & Matthias R. Baumgartner. (2017) Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1. Journal of Biological Chemistry 292:28, pages 11980-11991.
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Carlos R. Ferreira & William A. Gahl. (2017) Lysosomal storage diseases. Translational Science of Rare Diseases 2:1-2, pages 1-71.
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David Watkins & David S Rosenblatt. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 9 .
Christine Bassila, Rose Ghemrawi, Justine Flayac, D. Sean Froese, Matthias R. Baumgartner, Jean-Louis Guéant & David Coelho. (2017) Methionine synthase and methionine synthase reductase interact with MMACHC and with MMADHC. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863:1, pages 103-112.
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Insa Buers, Petra Pennekamp, Yvonne Nitschke, Chrishanthi Lowe, Boris V. Skryabin & Frank Rutsch. (2016) Lmbrd1 expression is essential for the initiation of gastrulation . Journal of Cellular and Molecular Medicine 20:8, pages 1523-1533.
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Kosuke Kawaguchi, Takumi Okamoto, Masashi Morita & Tsuneo Imanaka. (2016) Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1. Scientific Reports 6:1.
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Viktor Hlaváč & Pavel Souček. (2015) Role of family D ATP-binding cassette transporters (ABCD) in cancer. Biochemical Society Transactions 43:5, pages 937-942.
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