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Molecular Membrane Biology Volume 11, 1994 - Issue 2
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Original Article

A combined X-ray and neutron diffraction study of selectively deuterated melittin in phospholipid bilayers: effect of pH

J. P. Bradshaw Department of Preclinical Veterinary Sciences, Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Summerhall, Edinburgh, EH9 1QH, UK; Department of Biochemistry, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 1QH, UK
,
C. E. Dempsey Department of Biochemistry and Centre for Molecular Recognition, University of Bristol, Bristol, BS8 1TD, UK
&
A. Watts Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK
Pages 79-86 | Received 17 May 1993, Published online: 09 Jul 2009

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Burkhard Bechinger. (2004) Structure and Function of Membrane-Lytic Peptides. Critical Reviews in Plant Sciences 23:3, pages 271-292.
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L. I. Butenko, S. A. Kuleshova, J. V. Podgornaya, L. P. Myikots & A. B. Dmitriev. (2018) PHYSICO-CHEMICAL STUDIES OF APITOXIN AND PRODUCTS ON ITS BASIS. Pharmacy & Pharmacology 6:4, pages 351-366.
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Andrew Hung, Serdar Kuyucak, Christina I. Schroeder & Quentin Kaas. (2017) Modelling the interactions between animal venom peptides and membrane proteins. Neuropharmacology 127, pages 20-31.
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Julia Setzler, Carolin Seith, Martin Brieg & Wolfgang Wenzel. (2014) SLIM: An improved generalized Born implicit membrane model. Journal of Computational Chemistry 35:28, pages 2027-2039.
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Huan Zhan & Themis Lazaridis. (2013) Inclusion of Lateral Pressure/Curvature Stress Effects in Implicit Membrane Models. Biophysical Journal 104:3, pages 643-654.
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Mohan Babu Boggara, Mihaela Mihailescu & Ramanan Krishnamoorti. (2012) Structural Association of Nonsteroidal Anti-Inflammatory Drugs with Lipid Membranes. Journal of the American Chemical Society 134:48, pages 19669-19676.
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Sheeba J. Irudayam & Max L. Berkowitz. (2012) Binding and reorientation of melittin in a POPC bilayer: Computer simulations. Biochimica et Biophysica Acta (BBA) - Biomembranes 1818:12, pages 2975-2981.
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Sheeba J. Irudayam & Max L. Berkowitz. (2011) Influence of the arrangement and secondary structure of melittin peptides on the formation and stability of toroidal pores. Biochimica et Biophysica Acta (BBA) - Biomembranes 1808:9, pages 2258-2266.
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Moutusi Manna & Chaitali Mukhopadhyay. (2009) Cause and Effect of Melittin-Induced Pore Formation: A Computational Approach. Langmuir 25:20, pages 12235-12242.
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Justin A. Lemkul & David R. Bevan. (2009) Perturbation of membranes by the amyloid β-peptide - a molecular dynamics study. FEBS Journal 276:11, pages 3060-3075.
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H. Raghuraman & Amitabha Chattopadhyay. (2006) Melittin: a Membrane-active Peptide with Diverse Functions. Bioscience Reports 27:4-5, pages 189-223.
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H. Raghuraman & Amitabha Chattopadhyay. (2007) Orientation and Dynamics of Melittin in Membranes of Varying Composition Utilizing NBD Fluorescence. Biophysical Journal 92:4, pages 1271-1283.
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Durba Sengupta, Lars Meinhold, Dieter Langosch, G. Matthias Ullmann & Jeremy C. Smith. (2005) Understanding the energetics of helical peptide orientation in membranes. Proteins: Structure, Function, and Bioinformatics 58:4, pages 913-922.
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Themis Lazaridis. (2003) Effective energy function for proteins in lipid membranes. Proteins: Structure, Function, and Genetics 52:2, pages 176-192.
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Kalina Hristova, Christopher E. Dempsey & Stephen H. White. (2001) Structure, Location, and Lipid Perturbations of Melittin at the Membrane Interface. Biophysical Journal 80:2, pages 801-811.
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S. Krueger, C. W. Meuse, C. F. Majkrzak, J. A. Dura, N. F. Berk, M. Tarek & A. L. Plant. (2000) Investigation of Hybrid Bilayer Membranes with Neutron Reflectometry:  Probing the Interactions of Melittin. Langmuir 17:2, pages 511-521.
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John Katsaras & Thomas GutberletStephen H. White & Kalina Hristova. 2001. Lipid Bilayers. Lipid Bilayers 189 206 .
G. Fragneto, F. Graner, T. Charitat, P. Dubos & E. Bellet-Amalric. (2000) Interaction of the Third Helix of Antennapedia Homeodomain with a Deposited Phospholipid Bilayer:  A Neutron Reflectivity Structural Study. Langmuir 16:10, pages 4581-4588.
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Michal Bachar & Oren M. Becker. (2000) Protein-Induced Membrane Disorder: A Molecular Dynamics Study of Melittin in a Dipalmitoylphosphatidylcholine Bilayer. Biophysical Journal 78:3, pages 1359-1375.
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Burkhard Bechinger. (1999) The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy. Biochimica et Biophysica Acta (BBA) - Biomembranes 1462:1-2, pages 157-183.
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Gerhard Gröbner, Clemens Glaubitz & Anthony Watts. (1999) Probing Membrane Surfaces and the Location of Membrane-Embedded Peptides by 13C MAS NMR Using Lanthanide Ions. Journal of Magnetic Resonance 141:2, pages 335-339.
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Michal Bachar & Oren M. Becker. (1999) Melittin at a membrane/water interface: Effects on water orientation and water penetration. The Journal of Chemical Physics 111:18, pages 8672-8685.
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Kalina Hristova, William C. Wimley, Vinod K. Mishra, G.M. Anantharamiah, Jere P. Segrest & Stephen H. White. (1999) An amphipathic α-helix at a membrane interface: a structural study using a novel X-ray diffraction method 1 1Edited by D. C. Rees. Journal of Molecular Biology 290:1, pages 99-117.
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Jeremy P. BradshawRichard J. BushbyColin C. D. GilesMartin R. Saunders. (1999) Orientation of the Headgroup of Phosphatidylinositol in a Model Biomembrane As Determined by Neutron Diffraction. Biochemistry 38:26, pages 8393-8401.
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Simon Bernèche, Mafalda Nina & Benoît Roux. (1998) Molecular Dynamics Simulation of Melittin in a Dimyristoylphosphatidylcholine Bilayer Membrane. Biophysical Journal 75:4, pages 1603-1618.
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Yi Wu & Senfang Sui. (1998) Probing interaction of melittin with lipid membranes using liquid secondary ion mass spectrometry. Science in China Series B: Chemistry 41:1, pages 77-84.
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Jeremy P Bradshaw, Richard J Bushby, Colin C.D Giles, Martin R Saunders & Anand Saxena. (1997) The headgroup orientation of dimyristoylphosphatidylinositol-4-phosphate in mixed lipid bilayers: a neutron diffraction study. Biochimica et Biophysica Acta (BBA) - Biomembranes 1329:1, pages 124-138.
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Alexey S. Ladokhin. 1997. Flourescence Spectroscopy. Flourescence Spectroscopy 462 473 .
Mark E. Blaylock & Allan S. Hoffman. (1996) Affinity binding on argon plasma-immobilized biotinylated phospholipids. Plasmas and Polymers 1:3, pages 261-277.
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Jeremy P. Bradshaw, Richard J. Bushby, Colin C.D. Giles, Martin R. Saunders & David G. Reid. (1996) Neutron diffraction reveals the orientation of the headgroup of inositol lipids in model membranes. Nature Structural Biology 3:2, pages 125-127.
Crossref
J. P. Bradshaw, K. C. Duff, P. J. Gilchrist & A. M. Saxena. 1996. Neutrons in Biology. Neutrons in Biology 191 202 .
S. König, P. Méléard & D. Roux. (1994) A comparison of DMPC membranes mixed with melittin or C12E5. Il Nuovo Cimento D 16:9, pages 1585-1594.
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