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Sanath Kumar, Manjusha Lekshmi, Jerusha Stephen, Anely Ortiz-Alegria, Matthew Ayitah & Manuel F. Varela. (2023) Dynamics of efflux pumps in antimicrobial resistance, persistence, and community living of Vibrionaceae. Archives of Microbiology 206:1.
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Manuel F. Varela, Anely Ortiz-Alegria, Manjusha Lekshmi, Jerusha Stephen & Sanath Kumar. (2023) Functional Roles of the Conserved Amino Acid Sequence Motif C, the Antiporter Motif, in Membrane Transporters of the Major Facilitator Superfamily. Biology 12:10, pages 1336.
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Manuel F. Varela, Jerusha Stephen, Deeksha Bharti, Manjusha Lekshmi & Sanath Kumar. (2023) Inhibition of Multidrug Efflux Pumps Belonging to the Major Facilitator Superfamily in Bacterial Pathogens. Biomedicines 11:5, pages 1448.
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Jerusha Stephen, Fathima Salam, Manjusha Lekshmi, Sanath H. Kumar & Manuel F. Varela. (2023) The Major Facilitator Superfamily and Antimicrobial Resistance Efflux Pumps of the ESKAPEE Pathogen Staphylococcus aureus. Antibiotics 12:2, pages 343.
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P.V. Ragavendran, Vaishnavi Tripathi & Sheetal Gandotra. (2022) Structure prediction-based insights into the patatin family of Mycobacterium tuberculosis. Microbiology 168:12.
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Guoqing Zhai, Zhengyu Zhang & Changjiang Dong. (2022) Mutagenesis and functional analysis of SotB: A multidrug transporter of the major facilitator superfamily from Escherichia coli. Frontiers in Microbiology 13.
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Yan Shang, Peiwen Lv, Dandan Su, Yaru Li, Yu Liang, Cuiqing Ma & Chunyu Yang. (2021)
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Jerusha Stephen, Manjusha Lekshmi, Parvathi Ammini, Sanath H. Kumar & Manuel F. Varela. (2022) Membrane Efflux Pumps of Pathogenic Vibrio Species: Role in Antimicrobial Resistance and Virulence. Microorganisms 10:2, pages 382.
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Sushant Kumar, Arunabh Athreya, Ashutosh Gulati, Rahul Mony Nair, Ithayaraja Mahendran, Rakesh Ranjan & Aravind Penmatsa. (2021) Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Communications Biology 4:1.
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Manuel F. Varela, Jerusha Stephen, Manjusha Lekshmi, Manisha Ojha, Nicholas Wenzel, Leslie M. Sanford, Alberto J. Hernandez, Ammini Parvathi & Sanath H. Kumar. (2021) Bacterial Resistance to Antimicrobial Agents. Antibiotics 10:5, pages 593.
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Ilyas Alav, Jessica Kobylka, Miriam S. Kuth, Klaas M. Pos, Martin Picard, Jessica M. A. Blair & Vassiliy N. Bavro. (2021) Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria. Chemical Reviews 121:9, pages 5479-5596.
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Bing Zhang, Xue Liu, Elisabeth Lambert, Guillaume Mas, Sebastian Hiller, Jan-Willem Veening & Camilo Perez. (2020) Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis. Nature Structural & Molecular Biology 27:6, pages 561-569.
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Sanath Kumar, Manjusha Lekshmi, Ammini Parvathi, Manisha Ojha, Nicholas Wenzel & Manuel F. Varela. (2020) Functional and Structural Roles of the Major Facilitator Superfamily Bacterial Multidrug Efflux Pumps. Microorganisms 8:2, pages 266.
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Taru Singh, Sajad Ahmad Dar, Shukla Das & Shafiul Haque. 2020. Drug Discovery Targeting Drug-Resistant Bacteria. Drug Discovery Targeting Drug-Resistant Bacteria
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Manuel F Varela & Sanath Kumar. (2019) Strategies for discovery of new molecular targets for anti-infective drugs. Current Opinion in Pharmacology 48, pages 57-68.
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Poonam Vishwakarma, Atanu Banerjee, Ritu Pasrija, Rajendra Prasad & Andrew M. Lynn. (2018) Phylogenetic and conservation analyses of MFS transporters. 3 Biotech 8:11.
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Kumar Nagarathinam, Yoshiko Nakada-Nakura, Christoph Parthier, Tohru Terada, Narinobu Juge, Frank Jaenecke, Kehong Liu, Yunhon Hotta, Takaaki Miyaji, Hiroshi Omote, So Iwata, Norimichi Nomura, Milton T. Stubbs & Mikio Tanabe. (2018) Outward open conformation of a Major Facilitator Superfamily multidrug/H+ antiporter provides insights into switching mechanism. Nature Communications 9:1.
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Manjusha Lekshmi, Parvathi Ammini, Jones Adjei, Leslie M. Sanford, Ugina Shrestha, Sanath Kumar & Manuel F. Varela. (2018) Modulation of antimicrobial efflux pumps of the major facilitator superfamily in <em>Staphylococcus aureus</em>. AIMS Microbiology 4:1, pages 1-18.
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Ping Li, Yinzhong Gu, Jiang Li, Longxiang Xie, Xue Li & Jianping Xie. (2017) Mycobacterium tuberculosis Major Facilitator Superfamily Transporters. The Journal of Membrane Biology 250:6, pages 573-585.
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Karl A. Hassan, Annette Fagerlund, Liam D. H. Elbourne, Aniko Vörös, Jasmin K. Kroeger, Roger Simm, Nicolas J. Tourasse, Sarah Finke, Peter J. F. Henderson, Ole Andreas Økstad, Ian T. Paulsen & Anne-Brit Kolstø. (2017) The putative drug efflux systems of the Bacillus cereus group. PLOS ONE 12:5, pages e0176188.
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Sergio Romero-Romero, Froylan Gomez Lagunas & Daniel Balleza. (2017) Side chain flexibility and coupling between the S4-S5 linker and the TRP domain in thermo-sensitive TRP channels: Insights from protein modeling. Proteins: Structure, Function, and Bioinformatics 85:4, pages 630-646.
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Prathusha Kakarla, Ranjana KC, Ugina Shrestha, Indrika Ranaweera, Mun Mun Mukherjee, T. Mark Willmon, Alberto J. Hernandez, Sharla R. Barr & Manuel F. Varela. 2017. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer
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Jody Andersen, Gui-Xin He, Prathusha Kakarla, Ranjana KC, Sanath Kumar, Wazir Lakra, Mun Mukherjee, Indrika Ranaweera, Ugina Shrestha, Thuy Tran & Manuel Varela. (2015) Multidrug Efflux Pumps from Enterobacteriaceae, Vibrio cholerae and Staphylococcus aureus Bacterial Food Pathogens. International Journal of Environmental Research and Public Health 12:2, pages 1487-1547.
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P. Ryan Steed, Ping Zou, Kristin E. Trone & Hassane S. Mchaourab. (2013) Structure and pH-Induced Structural Rearrangements of the Putative Multidrug Efflux Pump EmrD in Liposomes Probed by Site-Directed Spin Labeling. Biochemistry 52:45, pages 7964-7974.
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Dana Yaffe, Sebastian Radestock, Yonatan Shuster, Lucy R. Forrest & Shimon Schuldiner. (2013) Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences 110:15.
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Jody L. Floyd, Kenneth P. Smith, Sanath H. Kumar, Jared T. Floyd & Manuel F. Varela. (2010)
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