1,214
Views
25
CrossRef citations to date
0
Altmetric
Review Article

Genomic medicine and risk prediction across the disease spectrumFootnote

, , , , , , , , , , , , , , , , , , , , , , , & show all
Pages 120-137 | Received 06 Jul 2014, Accepted 20 Nov 2014, Published online: 19 Jan 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Abisola O. Okunola, Karin J. Baatjes, Annalise E. Zemlin, Rispah Torrorey-Sawe, Magda Conradie, Martin Kidd, Rajiv T. Erasmus, Nerina C. van der Merwe & Maritha J. Kotze. (2023) Pathology-supported genetic testing for the application of breast cancer pharmacodiagnostics: family counselling, lifestyle adjustments and change of medication. Expert Review of Molecular Diagnostics 23:5, pages 431-443.
Read now
Demosthenes E. Ziogas, Ioannis D. Kyrochristos & Dimitrios H. Roukos. (2018) Next-generation sequencing: from conventional applications to breakthrough genomic analyses and precision oncology. Expert Review of Medical Devices 15:1, pages 1-3.
Read now
Anna Middleton. (2017) Your DNA, Your Say. The New Bioethics 23:1, pages 74-80.
Read now

Articles from other publishers (22)

Joseph H. Gallagher, Jason L. Vassy & Marla L. Clayman. (2023) Navigating the uncertainty of precision cancer screening: The role of shared decision-making. PEC Innovation 2, pages 100127.
Crossref
Carolyn Riley Chapman. (2022) Ethical, legal, and social implications of genetic risk prediction for multifactorial disease: a narrative review identifying concerns about interpretation and use of polygenic scores. Journal of Community Genetics.
Crossref
Hui-Lin Chin, Nour Gazzaz, Stephanie Huynh, Iulia Handra, Lynn Warnock, Ashley Moller-Hansen, Pierre Boerkoel, Julius O.B. Jacobsen, Christèle du Souich, Nan Zhang, Kent Shefchek, Leah M. Prentice, Nicole Washington, Melissa Haendel, Linlea Armstrong, Lorne Clarke, Wenhui Laura Li, Damian Smedley, Peter N. Robinson & Cornelius F. Boerkoel. (2022) The Clinical Variant Analysis Tool: Analyzing the evidence supporting reported genomic variation in clinical practice. Genetics in Medicine 24:7, pages 1512-1522.
Crossref
Kelly M. Schiabor Barrett, Max Masnick, Kathryn E. Hatchell, Juliann M. Savatt, Natalie Banet, Adam Buchanan & Huntington F. Willard. (2022) Clinical validation of genomic functional screen data: Analysis of observed BRCA1 variants in an unselected population cohort. Human Genetics and Genomics Advances 3:2, pages 100086.
Crossref
Lwando Mampunye, Nerina C. van der Merwe, Kathleen A. Grant, Armand V. Peeters, Rispah Torrorey-Sawe, David J. French, Kelebogile E. Moremi, Martin Kidd, Petrus C. van Eeden, Fredrieka M. Pienaar & Maritha J. Kotze. (2021) Pioneering BRCA1/2 Point-Of-Care Testing for Integration of Germline and Tumor Genetics in Breast Cancer Risk Management: A Vision for the Future of Translational Pharmacogenomics. Frontiers in Oncology 11.
Crossref
Lu Li & Vassilios Papadopoulos. (2021) Advances in stem cell research for the treatment of primary hypogonadism. Nature Reviews Urology 18:8, pages 487-507.
Crossref
Susan J. van Rensburg, Ronald van Toorn, Rajiv T. Erasmus, Coenraad Hattingh, Clint Johannes, Kelebogile E. Moremi, Merlisa C. Kemp, Penelope Engel-Hills & Maritha J. Kotze. (2021) Pathology-supported genetic testing as a method for disability prevention in multiple sclerosis (MS). Part I. Targeting a metabolic model rather than autoimmunity. Metabolic Brain Disease 36:6, pages 1151-1167.
Crossref
Mahwash Mukhtar, Saman Sargazi, Mahmood Barani, Henning Madry, Abbas Rahdar & Magali Cucchiarini. (2021) Application of Nanotechnology for Sensitive Detection of Low-Abundance Single-Nucleotide Variations in Genomic DNA: A Review. Nanomaterials 11:6, pages 1384.
Crossref
Matteo Chiara, Pietro Mandreoli, Marco Antonio Tangaro, Anna Maria D’Erchia, Sandro Sorrentino, Cinzia Forleo, David S Horner, Federico Zambelli & Graziano Pesole. (2020) VINYL: Variant prIoritizatioN bY survivaL analysis. Bioinformatics 36:24, pages 5590-5599.
Crossref
Jaco Oosthuizen, Maritha J. Kotze, Nicole Van Der Merwe, Ettienne J. Myburgh, Phillip Bester & Nerina C. van der Merwe. (2021) Globally Rare BRCA2 Variants With Founder Haplotypes in the South African Population: Implications for Point-of-Care Testing Based on a Single-Institution BRCA1/2 Next-Generation Sequencing Study. Frontiers in Oncology 10.
Crossref
Rispah Torrorey-Sawe, Nicole van der Merwe, Simeon Kipkoech Mining & Maritha J. Kotze. (2020) Pioneering Informed Consent for Return of Research Results to Breast Cancer Patients Facing Barriers to Implementation of Genomic Medicine: The Kenyan BRCA1/2 Testing Experience Using Whole Exome Sequencing. Frontiers in Genetics 11.
Crossref
Giuseppe Novelli, Michela Biancolella, Andrea Latini, Aldo Spallone, Paola Borgiani & Marisa Papaluca. (2020) Precision Medicine in Non-Communicable Diseases. High-Throughput 9:1, pages 3.
Crossref
Julia Citron, Emma Willcocks, George Crowley, Sophia Kwon & Anna Nolan. (2019) Genomics of Particulate Matter Exposure Associated Cardiopulmonary Disease: A Narrative Review. International Journal of Environmental Research and Public Health 16:22, pages 4335.
Crossref
Ann Chen Wu, James P. Kiley, Patricia J. Noel, Shashi Amur, Esteban G. Burchard, John P. Clancy, Joshua Galanter, Maki Inada, Tiffanie K. Jones, Jonathan A. Kropski, James E. Loyd, Lawrence M. Nogee, Benjamin A. Raby, Angela J. Rogers, David A. Schwartz, Don D. Sin, Avrum Spira, Scott T. Weiss, Lisa R. Young & Blanca E. Himes. (2018) Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement. American Journal of Respiratory and Critical Care Medicine 198:12, pages e116-e136.
Crossref
Galina Hovhannisyan, Tigran Harutyunyan & Rouben Aroutiounian. (2018) Micronuclei and What They Can Tell Us in Cytogenetic Diagnostics. Current Genetic Medicine Reports 6:4, pages 144-154.
Crossref
Aniwaa Owusu Obeng, Kezhen Fei, Kenneth Levy, Amanda Elsey, Toni Pollin, Andrea Ramirez, Kristin Weitzel & Carol Horowitz. (2018) Physician-Reported Benefits and Barriers to Clinical Implementation of Genomic Medicine: A Multi-Site IGNITE-Network Survey. Journal of Personalized Medicine 8:3, pages 24.
Crossref
Nicola Mulder. (2017) Development to enable precision medicine in Africa. Personalized Medicine 14:6, pages 467-470.
Crossref
Matteo Chiara & Giulio Pavesi. (2017) Evaluation of Quality Assessment Protocols for High Throughput Genome Resequencing Data. Frontiers in Genetics 8.
Crossref
Nicole van der Merwe, Armand Peeters, Fredrieka Pienaar, Juanita Bezuidenhout, Susan van Rensburg & Maritha Kotze. (2017) Exome Sequencing in a Family with Luminal-Type Breast Cancer Underpinned by Variation in the Methylation Pathway. International Journal of Molecular Sciences 18:2, pages 467.
Crossref
Jonathan Roberts & Anna Middleton. (2018) Genetics in the 21st Century: Implications for patients, consumers and citizens. F1000Research 6, pages 2020.
Crossref
M. Elizabeth Fini, Stephen G. Schwartz, Xiaoyi Gao, Shinwu Jeong, Nitin Patel, Tatsuo Itakura, Marianne O. Price, Francis W. PriceJr.Jr., Rohit Varma & W. Daniel Stamer. (2017) Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine. Progress in Retinal and Eye Research 56, pages 58-83.
Crossref
Lynnette R. Ferguson, Bobbi Laing, Gareth Marlow & Karen Bishop. (2016) The role of vitamin D in reducing gastrointestinal disease risk and assessment of individual dietary intake needs: Focus on genetic and genomic technologies. Molecular Nutrition & Food Research 60:1, pages 119-133.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.