1,953
Views
133
CrossRef citations to date
0
Altmetric
Review Article

Adipocyte size as a determinant of metabolic disease and adipose tissue dysfunction

, , , &
Pages 301-313 | Received 09 Jan 2015, Accepted 04 Apr 2015, Published online: 17 Aug 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Eve-Julie Tremblay, André Tchernof, Mélissa Pelletier, Nicolas Chabot, Denis R. Joanisse & Pascale Mauriège. (2022) Contribution of markers of adiposopathy and adipose cell size in predicting insulin resistance in women of varying age and adiposity. Adipocyte 11:1, pages 175-189.
Read now
Ville A Palomäki, Vesa Koivukangas, Sanna Meriläinen, Petri Lehenkari & Tuomo J Karttunen. (2022) A Straightforward Method for Adipocyte Size and Count Analysis Using Open-source Software QuPath. Adipocyte 11:1, pages 99-107.
Read now
Prasad G. Kamble, Maria J. Pereira, Stefan Gustafsson, Per Lundkvist, Casimiro Castillejo-López, Tove Fall, Erik Ingelsson & Jan W. Eriksson. (2018) Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover. Adipocyte 7:4, pages 285-296.
Read now
Henrik Svensson, Daniel Olausson, Agneta Holmäng, Eva Jennische, Staffan Edén & Malin Lönn. (2018) Free lipid and computerized determination of adipocyte size. Adipocyte 7:3, pages 180-182.
Read now
Paula A. Lopes, Narcisa M. Bandarra, Susana V. Martins, Marta S. Madeira, Júlia Ferreira, José L. Guil-Guerrero & José A. M. Prates. (2018) Docosahexaenoic acid (DHA) at the sn-2 position of triacylglycerols increases DHA incorporation in brown, but not in white adipose tissue, of hamsters. International Journal of Food Sciences and Nutrition 69:4, pages 458-471.
Read now

Articles from other publishers (128)

Miguel Hernández-Quiles, Laura Martinez Campesino, Imogen Morris, Zabran Ilyas, Steve Reynolds, Nguan Soon Tan, Paula Sobrevals Alcaraz, Edwin C.A. Stigter, Ákos Varga, János Varga, Robert van Es, Harmjan Vos, Heather L. Wilson, Endre Kiss-Toth & Eric Kalkhoven. (2023) The pseudokinase TRIB3 controls adipocyte lipid homeostasis and proliferation in vitro and in vivo. Molecular Metabolism 78, pages 101829.
Crossref
Xiaoyun Cheng, Shuhan Jiang, Boyu Pan, Wei Xie & Jie Meng. (2023) Ectopic and visceral fat deposition in aging, obesity, and idiopathic pulmonary fibrosis: an interconnected role. Lipids in Health and Disease 22:1.
Crossref
Aneliya Parvanova, Elia Reseghetti, Manuela Abbate & Piero Ruggenenti. (2023) Mechanisms and treatment of obesity-related hypertension—Part 1: Mechanisms. Clinical Kidney Journal.
Crossref
Óscar Osorio-Conles, Amanda Jiménez, Ainitze Ibarzabal, José María Balibrea, Ana de Hollanda & Josep Vidal. (2023) Limited Bariatric Surgery-induced Weight Loss in Subjects With Type 2 Diabetes: Predictor Variables in Adipose Tissue. The Journal of Clinical Endocrinology & Metabolism 108:11, pages e1205-e1213.
Crossref
Jin Tae Kim, Jing Chen, Yimeng Zhou, Moon Jeong Son, Dong Hyeon Jeon, Jung Won Kwon, Ga Yeon Lee & Hong Jin Lee. (2023) Cycloastragenol inhibits adipogenesis and fat accumulation in vitro and in vivo through activating Hedgehog signaling. Food Science and Biotechnology.
Crossref
Elna Dickson, Claes Fryklund, Rana Soylu-Kucharz, Marie Sjögren, Karin G. Stenkula & Maria Björkqvist. (2023) Altered Adipocyte Cell Size Distribution Prior to Weight Loss in the R6/2 Model of Huntington’s Disease. Journal of Huntington's Disease, pages 1-14.
Crossref
Annika Nerstedt & Ulf Smith. (2023) The impact of cellular senescence in human adipose tissue. Journal of Cell Communication and Signaling 17:3, pages 563-573.
Crossref
Avital Horwitz & Ruth Birk. (2023) Adipose Tissue Hyperplasia and Hypertrophy in Common and Syndromic Obesity—The Case of BBS Obesity. Nutrients 15:15, pages 3445.
Crossref
Lasse K Markussen & Susanne Mandrup. (2023) Adipocyte gene expression in obesity — insights gained and challenges ahead. Current Opinion in Genetics & Development 81, pages 102060.
Crossref
Yifan Guo, Qilong Zhang, Lifang Zheng, Jian Shou, Shuzhao Zhuang, Weihua Xiao & Peijie Chen. (2023) Depot-specific adaption of adipose tissue for different exercise approaches in high-fat diet/streptozocin-induced diabetic mice. Frontiers in Physiology 14.
Crossref
Alyson Deprez, Marie‐Amélie Lukaszewski, Coraline De Sousa Do Outeiro, Jéssica H. Poletto Bonetto, Ying He, Anik Cloutier, Daniela Ravizzoni Dartora & Anne Monique Nuyt. (2023) Neonatal hyperoxia leads to white adipose tissue remodeling and susceptibility to hypercaloric diet. Physiological Reports 11:13.
Crossref
Pedro L. Valenzuela, Pedro Carrera-Bastos, Adrián Castillo-García, Daniel E. Lieberman, Alejandro Santos-Lozano & Alejandro Lucia. (2023) Obesity and the risk of cardiometabolic diseases. Nature Reviews Cardiology 20:7, pages 475-494.
Crossref
Ishwarlal Jialal, Beverley Adams-Huet & Sridevi Devaraj. (2023) Increased Adipocyte Hypertrophy in Patients with Nascent Metabolic Syndrome. Journal of Clinical Medicine 12:13, pages 4247.
Crossref
Suyeon Jeon, Jungu Lee, Yujin Shin & Michung Yoon. (2023) Ascorbic acid reduces insulin resistance and pancreatic steatosis by regulating adipocyte hypertrophy in obese ovariectomized mice. Canadian Journal of Physiology and Pharmacology 101:6, pages 294-303.
Crossref
Weiqi Xu, Yujie Huang, Sainan Tao, Wangting Zhou, Yujia Peng, Wei Dong, Xuhui Kan, Guijie Chen, Xiaoxiong Zeng & Zhonghua Liu. (2023) Effects of long-term administration of theasinensin A on healthy C57BL/6J mice: Enhancing the function of epididymal white adipose tissue and regulating the colonic microenvironment. Food Chemistry 403, pages 134477.
Crossref
昱鹏 熊. (2023) Mechanisms and Research Progress Relatedto Obesity and Metabolic Syndrome. Advances in Clinical Medicine 13:09, pages 14560-14568.
Crossref
Chooi Yeng Lee. (2023) Effects of dietary vitamins on obesity-related metabolic parameters. Journal of Nutritional Science 12.
Crossref
Rohan Varshney, Snehasis Das, G. Devon Trahan, Jacob W. Farriester, Gregory P. Mullen, Gertrude Kyere-Davies, David M. Presby, Julie A. Houck, Patricia G. Webb, Monika Dzieciatkowska, Kenneth L. Jones, Matthew S. Rodeheffer, Jacob E. Friedman, Paul S. MacLean & Michael C. Rudolph. (2023) Neonatal intake of Omega-3 fatty acids enhances lipid oxidation in adipocyte precursors. iScience 26:1, pages 105750.
Crossref
Frédérique Proulx, Giada Ostinelli, Laurent Biertho & André Tchernof. 2023. Duodenal Switch and Its Derivatives in Bariatric and Metabolic Surgery. Duodenal Switch and Its Derivatives in Bariatric and Metabolic Surgery 69 83 .
Teresa Salvatore, Raffaele Galiero, Alfredo Caturano, Luca Rinaldi, Livio Criscuolo, Anna Di Martino, Gaetana Albanese, Erica Vetrano, Christian Catalini, Celestino Sardu, Giovanni Docimo, Raffaele Marfella & Ferdinando Carlo Sasso. (2022) Current Knowledge on the Pathophysiology of Lean/Normal-Weight Type 2 Diabetes. International Journal of Molecular Sciences 24:1, pages 658.
Crossref
A Králová, H Kubátová, S Kauerová, L Janoušek, J Froněk, I Králová Lesná & R Poledne. (2022) Cholesterol efflux and macrophage polarization in human adipose tissue. Physiological Research 71:6, pages 859-868.
Crossref
Damien Chua, Zun Siong Low, Guo Xiang Cheam, Aik Seng Ng & Nguan Soon Tan. (2022) Utility of Human Relevant Preclinical Animal Models in Navigating NAFLD to MAFLD Paradigm. International Journal of Molecular Sciences 23:23, pages 14762.
Crossref
Qian Li & Kirsty L. Spalding. (2022) The regulation of adipocyte growth in white adipose tissue. Frontiers in Cell and Developmental Biology 10.
Crossref
Daniel M. Davies, Kim van den Handel, Soham Bharadwaj & Jette Lengefeld. (2022) Cellular enlargement - A new hallmark of aging?. Frontiers in Cell and Developmental Biology 10.
Crossref
Nadav Kislev, Shira Eidelheit, Shaked Perlmutter & Dafna Benayahu. (2022) How to follow lipid droplets dynamics during adipocyte metabolism. Journal of Cellular Physiology 237:11, pages 4157-4168.
Crossref
Guan Wang, Anying Song, Marie Bae & Qiong A. Wang. 2011. Comprehensive Physiology. Comprehensive Physiology 4119 4132 .
Laura R. Cechinel, Rachael A. Batabyal, Robert J. Freishtat & Irene E. Zohn. (2022) Parental obesity-induced changes in developmental programming. Frontiers in Cell and Developmental Biology 10.
Crossref
L. Turner, M.-F. Gauthier, A. Lafortune, A. Tchernof & S. Santosa. (2022) Adipocyte size, adipose tissue fibrosis, macrophage infiltration and disease risk are different in younger and older individuals with childhood versus adulthood onset obesity. International Journal of Obesity 46:10, pages 1859-1866.
Crossref
Giada Ostinelli, Sofia Laforest, Scott G Denham, Marie-Frederique Gauthier, Virginie Drolet-Labelle, Emma Scott, Frédéric-Simon Hould, Simon Marceau, Natalie Z M Homer, Catherine Bégin, Ruth Andrew & André Tchernof. (2022) Increased Adipose Tissue Indices of Androgen Catabolism and Aromatization in Women With Metabolic Dysfunction. The Journal of Clinical Endocrinology & Metabolism 107:8, pages e3330-e3342.
Crossref
Qian Li & Kirsty L. Spalding. (2022) Profiling hypertrophic adipocytes in humans, from transcriptomics to diagnostics. eBioMedicine 81, pages 104105.
Crossref
Son Tien Nguyen, Naoto Fujita, Takaya Oshima, Misuzu Nishihira, Haruya Ohno, Masayasu Yoneda & Susumu Urakawa. (2022) Effects of long-term childhood exercise and detraining on lipid accumulation in metabolic-related organs. PLOS ONE 17:6, pages e0270330.
Crossref
Feng Yue, Lihong Du, Ruyu Wang, Baoquan Han, Xiaojun Zhang, Zhangzhang Yao, Wenqiang Zhang, Chang Cai, Zhiying Zhang & Kun Xu. (2022) In vivo Protein Interference: Oral Administration of Recombinant Yeast-Mediated Partial Leptin Reduction for Obesity Control. Frontiers in Microbiology 13.
Crossref
Julius Honecker, Stefan Ruschke, Claudine Seeliger, Samantha Laber, Sophie Strobel, Priska Pröll, Christoffer Nellaker, Cecilia M. Lindgren, Ulrich Kulozik, Josef Ecker, Dimitrios C. Karampinos, Melina Claussnitzer & Hans Hauner. (2022) Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue. eBioMedicine 79, pages 104020.
Crossref
Yair Pincu, Uri Yoel, Yulia Haim, Nataly Makarenkov, Nitzan Maixner, Ruthy Shaco-Levy, Nava Bashan, Dror Dicker & Assaf Rudich. (2022) Assessing Obesity-Related Adipose Tissue Disease (OrAD) to Improve Precision Medicine for Patients Living With Obesity. Frontiers in Endocrinology 13.
Crossref
Yuan Gao, Shihan Yuan, Yuze Chen, Fang Liu, Zihao Wei, Wanxiu Cao, Robert W. Li, Jie Xu, Changhu Xue & Qingjuan Tang. (2022) The improvement effect of astaxanthin-loaded emulsions on obesity is better than that of astaxanthin in the oil phase. Food & Function 13:6, pages 3720-3731.
Crossref
Kerri Z. Delaney & Sylvia Santosa. (2022) Sex differences in regional adipose tissue depots pose different threats for the development of Type 2 diabetes in males and females. Obesity Reviews 23:3.
Crossref
Carrasco N. Fernando & Carrasco N. Gabriela. (2022) Identificación del fenotipo ahorrador para la personalización del manejo del sobrepeso y la obesidad. Revista Médica Clínica Las Condes 33:2, pages 154-162.
Crossref
Xiao‐Yan Huang, Ji‐Xiong Chen, Yi Ren, Li‐Chun Fan, Wei Xiang & Xiao‐Jie He. (2022) Exosomal miR‐122 promotes adipogenesis and aggravates obesity through the VDR/SREBF1 axis. Obesity 30:3, pages 666-679.
Crossref
Dilong Wang, Qiuyan Mai, Xiuyan Yang, Xinjin Chi, Ruohan Li, Jian Jiang, Liang Luo, Xiaoyi Fang, Peng Yun, Liyang Liang, Guang Yang, Kun Song, Liang Fang, Yun Chen, Ying Zhang, Yulong He, Ningning Li & Yihang Pan. (2022) Microduplication of 16p11.2 locus Potentiates Hypertrophic Obesity in Association with Imbalanced Triglyceride Metabolism in White Adipose Tissue . Molecular Nutrition & Food Research 66:5.
Crossref
Run Zhou Ye, Gabriel Richard, Nicolas Gévry, André Tchernof & André C Carpentier. (2022) Fat Cell Size: Measurement Methods, Pathophysiological Origins, and Relationships With Metabolic Dysregulations. Endocrine Reviews 43:1, pages 35-60.
Crossref
Yusuke Higuchi, Takehiro Ogata, Naohiko Nakanishi, Masahiro Nishi, Akira Sakamoto, Yumika Tsuji, Shinya Tomita & Satoaki Matoba. (2022) Requirement of Cavin-2 for the expression and stability of IRβ in adequate adipocyte differentiation. Molecular Metabolism 55, pages 101416.
Crossref
Simon T. Bond, Anna C. Calkin & Brian G. Drew. (2021) Sex differences in white adipose tissue expansion: emerging molecular mechanisms. Clinical Science 135:24, pages 2691-2708.
Crossref
Elizabeth M Cespedes Feliciano, Renate M Winkels, Jeffrey A Meyerhardt, Carla M Prado, Lydia A Afman & Bette J Caan. (2021) Abdominal adipose tissue radiodensity is associated with survival after colorectal cancer. The American Journal of Clinical Nutrition 114:6, pages 1917-1924.
Crossref
Cara Trivett, Zoe J. Lees & Dilys J. Freeman. (2021) Adipose tissue function in healthy pregnancy, gestational diabetes mellitus and pre-eclampsia. European Journal of Clinical Nutrition 75:12, pages 1745-1756.
Crossref
Andrew McColloch, Hanli Liu & Michael Cho. (2021) Reversal of stem cell‐derived hypertrophic adipocytes mediated by photobiomodulation (1064 nm). Translational Biophotonics 3:4.
Crossref
Anna Hanttu, Sauli VuotiPia KiveläPerttu ArkkilaNina LundbomAntti HakkarainenJesper LundbomTiina LehtimäkiHanna ViskariVille LehtinenKirsi H. PietiläinenJussi Sutinen. (2021) Liver Fat, Adipose Tissue, and Body Composition Changes After Switching from a Protease Inhibitor or Efavirenz to Raltegravir. AIDS Patient Care and STDs 35:9, pages 335-341.
Crossref
Dominik Weidlich, Julius Honecker, Christof Boehm, Stefan Ruschke, Daniela Junker, Anh T. Van, Marcus R. Makowski, Christina Holzapfel, Melina Claussnitzer, Hans Hauner & Dimitrios C. Karampinos. (2021) Lipid droplet–size mapping in human adipose tissue using a clinical 3T system. Magnetic Resonance in Medicine 86:3, pages 1256-1270.
Crossref
Senem Aykul, Jordan Maust, Vijayalakshmi Thamilselvan, Monique Floer & Erik Martinez-Hackert. (2021) Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis. International Journal of Molecular Sciences 22:16, pages 8472.
Crossref
Sung-Gyu Lee & Hyun Kang. (2021) Anti-Obesity and Lipid Metabolism Effects of Ulmus davidiana var. japonica in Mice Fed a High-Fat Diet . Journal of Microbiology and Biotechnology 31:7, pages 1011-1021.
Crossref
Monika Kubacka, Szczepan Mogilski, Monika Zadrożna, Barbara Nowak, Małgorzata Szafarz, Bartosz Pomierny, Henryk Marona, Anna Waszkielewicz, Wojciech Jawień, Jacek Sapa, Marek Bednarski, Joanna Knutelska & Magdalena Kotańska. (2021) MH-76, a Novel Non-Quinazoline α1-Adrenoceptor Antagonist, but Not Prazosin Reduces Inflammation and Improves Insulin Signaling in Adipose Tissue of Fructose-Fed Rats. Pharmaceuticals 14:5, pages 477.
Crossref
Pauline Morigny, Jeremie Boucher, Peter Arner & Dominique Langin. (2021) Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics. Nature Reviews Endocrinology 17:5, pages 276-295.
Crossref
Giada Ostinelli, Jinchu Vijay, Marie-Claude Vohl, Elin Grundberg & Andre Tchernof. (2021) AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants. Molecular and Cellular Endocrinology 527, pages 111220.
Crossref
Stefanie Schreyer, Nikolaus Berndt, Johannes Eckstein, Michael Mülleder, Shabnam Hemmati-Sadeghi, Charlotte Klein, Basim Abuelnor, Alina Panzel, David Meierhofer, Joachim Spranger, Barbara Steiner & Sebastian Brachs. (2021) Dietary-challenged mice with Alzheimer-like pathology show increased energy expenditure and reduced adipocyte hypertrophy and steatosis. Aging 13:8, pages 10891-10919.
Crossref
Guihuan Li, Zhe Xing, Wenyang Wang, Wenyang Luo, Zunya Ma, Zhicong Wu, Hua Chen, Yuhao Li, Chunxia Wang, Fangyin Zeng & Fan Deng. (2021) Adipose-specific knockout of Protein Kinase D1 suppresses de novo lipogenesis in mice via SREBP1c-dependent signaling. Experimental Cell Research 401:2, pages 112548.
Crossref
Toshiaki Iwase, Xiaoping Wang, Tushaar Vishal Shrimanker, Mikhail G. Kolonin & Naoto T. Ueno. (2021) Body composition and breast cancer risk and treatment: mechanisms and impact. Breast Cancer Research and Treatment 186:2, pages 273-283.
Crossref
Natalie Theobalt, Isabel Hofmann, Sonja Fiedler, Simone Renner, Georg Dhom, Annette Feuchtinger, Axel Walch, Martin Hrabĕ de Angelis, Eckhard Wolf, Rüdiger Wanke & Andreas Blutke. (2021) Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy. PLOS ONE 16:3, pages e0248594.
Crossref
Sofia Laforest, Kaoutar Ennour-Idrissi, Geneviève Ouellette, Marie-Frédérique Gauthier, Annick Michaud, Francine Durocher, André Tchernof & Caroline Diorio. (2020) Associations between markers of mammary adipose tissue dysfunction and breast cancer prognostic factors. International Journal of Obesity 45:1, pages 195-205.
Crossref
P. Morigny & D. Langin. 2021. Les Obésités. Les Obésités 179 182 .
Niklas Mejhert & Mikael Rydén. (2020) Novel aspects on the role of white adipose tissue in type 2 diabetes. Current Opinion in Pharmacology 55, pages 47-52.
Crossref
Valentina Ceccarelli, Ilaria Barchetta, Flavia Agata Cimini, Laura Bertoccini, Caterina Chiappetta, Danila Capoccia, Raffaella Carletti, Claudio Di Cristofano, Gianfranco Silecchia, Mario Fontana, Frida Leonetti, Andrea Lenzi, Marco Giorgio Baroni, Eugenio Barone & Maria Gisella Cavallo. (2020) Reduced Biliverdin Reductase-A Expression in Visceral Adipose Tissue is Associated with Adipocyte Dysfunction and NAFLD in Human Obesity. International Journal of Molecular Sciences 21:23, pages 9091.
Crossref
Benjamin D. Pope, Curtis R. Warren, Madeleine O. Dahl, Christina V. Pizza, Douglas E. Henze, Nina R. Sinatra, Grant M. Gonzalez, Huibin Chang, Qihan Liu, Aaron L. Glieberman, John P. Ferrier, Chad A. Cowan & Kevin Kit Parker. (2020) Fattening chips: hypertrophy, feeding, and fasting of human white adipocytes in vitro . Lab on a Chip 20:22, pages 4152-4165.
Crossref
Alan Ramalho, Nadine Leblanc, Marie-Gil Fortin, André Marette, André Tchernof & Hélène Jacques. (2020) Characterization of a Coproduct from the Sea Cucumber Cucumaria frondosa and Its Effects on Visceral Adipocyte Size in Male Wistar Rats. Marine Drugs 18:11, pages 530.
Crossref
Haodong Zhou, Guy Trudel, Konstantin Alexeev, Justin Thomas & Odette Laneuville. (2020) Hyperplasia and accelerated hypertrophy of marrow adipocytes with knee immobilization were sustained despite remobilization. Journal of Applied Physiology 129:4, pages 701-708.
Crossref
Jingyan GuanYunfan HeXinhui WangYao YaoYe LiZijue WangYunzi ChenZiqing DongFeng Lu. (2020) Identification of High-Quality Fat Based on Precision Centrifugation in Lipoaspirates Using Marker Floats. Plastic & Reconstructive Surgery 146:3, pages 541-550.
Crossref
Purificación Ros, Francisca Díaz, Alejandra Freire-Regatillo, Pilar Argente-Arizón, Vicente Barrios, Jesús Argente & Julie A Chowen. (2020) Sex Differences in Long-term Metabolic Effects of Maternal Resveratrol Intake in Adult Rat Offspring. Endocrinology 161:8.
Crossref
Sanna Maria Honkala, Piryanka Motiani, Riikka Kivelä, Karthik Amudhala Hemanthakumar, Erik Tolvanen, Kumail Kumar Motiani, Jari-Joonas Eskelinen, Kirsi A Virtanen, Jukka Kemppainen, Marja Anneli Heiskanen, Eliisa Löyttyniemi, Pirjo Nuutila, Kari K Kalliokoski & Jarna Christina Hannukainen. (2020) Exercise training improves adipose tissue metabolism and vasculature regardless of baseline glucose tolerance and sex. BMJ Open Diabetes Research & Care 8:1, pages e000830.
Crossref
Fiona Allum & Elin Grundberg. (2020) Capturing functional epigenomes for insight into metabolic diseases. Molecular Metabolism 38, pages 100936.
Crossref
Marwa S. Hamza, Moustafa Sayed & Salama Salama. (2020) 2-Methoxyestradiol inhibits high fat diet-induced obesity in rats through modulation of adipose tissue macrophage infiltration and immunophenotype. European Journal of Pharmacology 878, pages 173106.
Crossref
Tongtong Zhang, Hongtao Liu, Rui Mao, Huawu Yang, Yuanchuan Zhang, Yu Zhang, Pengsen Guo, Dafang Zhan, Bin Xiang & Yanjun Liu. (2020) The lncRNA RP11-142A22.4 promotes adipogenesis by sponging miR-587 to modulate Wnt5β expression. Cell Death & Disease 11:6.
Crossref
Laura L. Gonzalez, Karin Garrie & Mark D. Turner. (2020) Role of S100 proteins in health and disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:6, pages 118677.
Crossref
Tim Hollstein & Paolo Piaggi. (2020) Metabolic Factors Determining the Susceptibility to Weight Gain: Current Evidence. Current Obesity Reports 9:2, pages 121-135.
Crossref
Marie-Eve PichéAndré TchernofJean-Pierre Després. (2020) Obesity Phenotypes, Diabetes, and Cardiovascular Diseases. Circulation Research 126:11, pages 1477-1500.
Crossref
Hiroko Horiuchi, Kohei Kamikado, Ryo Aoki, Natsuki Suganuma, Tomohiko Nishijima, Akiho Nakatani & Ikuo Kimura. (2020) Bifidobacterium animalis subsp. lactis GCL2505 modulates host energy metabolism via the short-chain fatty acid receptor GPR43. Scientific Reports 10:1.
Crossref
Lailan Safina Nasution, Ahmad Aulia Jusuf, Sri Widia Jusman & Mohamad Sadikin. (2020) Hypoxia and autophagic response of obese adult rat adipocytes which differ in nutritional state during childhood. Journal of Clinical Biochemistry and Nutrition 66:2, pages 132-138.
Crossref
Alessandra Feraco, Vincenzo Marzolla, Angelo Scuteri, Andrea Armani & Massimiliano Caprio. (2020) Mineralocorticoid Receptors in Metabolic Syndrome: From Physiology to Disease. Trends in Endocrinology & Metabolism 31:3, pages 205-217.
Crossref
Zhendong Sun, Zhi Tang, Xiaoxi Yang, Qian S. Liu, Yong Liang, Heidelore Fiedler, Jianqing Zhang, Qunfang Zhou & Guibin Jiang. (2020) Perturbation of 3-tert-butyl-4-hydroxyanisole in adipogenesis of male mice with normal and high fat diets. Science of The Total Environment 703, pages 135608.
Crossref
Jinchu Vijay, Marie-Frédérique Gauthier, Rebecca L. Biswell, Daniel A. Louiselle, Jeffrey J. Johnston, Warren A. Cheung, Bradley Belden, Albena Pramatarova, Laurent Biertho, Margaret Gibson, Marie-Michelle Simon, Haig Djambazian, Alfredo Staffa, Guillaume Bourque, Anita Laitinen, Johanna Nystedt, Marie-Claude Vohl, Jason D. Fraser, Tomi Pastinen, André Tchernof & Elin Grundberg. (2019) Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types. Nature Metabolism 2:1, pages 97-109.
Crossref
Joanne T.M. Tan, Victoria A. Nankivell, Carmel Bilu, Tomer Shemesh, Stephen J. Nicholls, Paul Zimmet, Noga Kronfeld-Schor, Alex Brown & Christina A. Bursill. (2019) High-Energy Diet and Shorter Light Exposure Drives Markers of Adipocyte Dysfunction in Visceral and Subcutaneous Adipose Depots of Psammomys obesus. International Journal of Molecular Sciences 20:24, pages 6291.
Crossref
Nathan F. Denton, Mohamed Eghleilib, Sama Al-Sharifi, Marijana Todorčević, Matt J. Neville, Nellie Loh, Alexander Drakesmith, Fredrik Karpe & Katherine E. Pinnick. (2019) Bone morphogenetic protein 2 is a depot-specific regulator of human adipogenesis. International Journal of Obesity 43:12, pages 2458-2468.
Crossref
Assel Sarsenbayeva, Cátia M. Marques-Santos, Ketan Thombare, Giada Di Nunzio, Kristina E. Almby, Martin Lundqvist, Jan W. Eriksson & Maria J. Pereira. (2019) Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism. Psychoneuroendocrinology 110, pages 104445.
Crossref
Zijian Fang, Susan Pyne & Nigel J. Pyne. (2019) WITHDRAWN: Ceramide and Sphingosine 1-Phosphate in adipose dysfunction. Progress in Lipid Research, pages 100991.
Crossref
Zhihui Yu, Ning Wang, Gan Hu & Meihu Ma. (2019) Comparison of long-term effects of egg yolk consumption under normal and high fat diet on lipid metabolism and fatty acids profile in mice. Food Science and Biotechnology 28:4, pages 1195-1206.
Crossref
M. Rydén, P. Petrus, D. P. Andersson, G. Medina‐Gómez, E. Escasany, P. Corrales Cordón, I. Dahlman, A. Kulyté & P. Arner. (2019) Insulin action is severely impaired in adipocytes of apparently healthy overweight and obese subjects. Journal of Internal Medicine 285:5, pages 578-588.
Crossref
Zijian Fang, Susan Pyne & Nigel J. Pyne. (2019) Ceramide and sphingosine 1-phosphate in adipose dysfunction. Progress in Lipid Research 74, pages 145-159.
Crossref
Jennifer Labrecque, Andréanne Michaud, Marie-Frédérique Gauthier, Mélissa Pelletier, François Julien, Léonie Bouvet-Bouchard & André Tchernof. (2019) Interleukin-1β and prostaglandin-synthesizing enzymes as modulators of human omental and subcutaneous adipose tissue function. Prostaglandins, Leukotrienes and Essential Fatty Acids 141, pages 9-16.
Crossref
Paul B. Higgins, Franco Folli, Marcia C. R. Andrade, Jaydee Foster, Vicki Mattern, Rita Paroni, Natalia Schlabritz-Loutsevitch, V. Saroja Voruganti, Shyamesh Kumar, Rodolfo Guardado-Mendoza, Gaetano Bulfamante, Paolo Fiorina, Antonio E. Pontiroli, Gene B. Hubbard, Michael Owston, Edward J. Dick & Anthony G. Comuzzie. (2019) Duodenal adipose tissue is associated with obesity in baboons (Papio sp): a novel site of ectopic fat deposition in non-human primates. Acta Diabetologica 56:2, pages 227-236.
Crossref
Younghyun Park, Joonseong Jang, Dongju Lee & Michung Yoon. (2018) Vitamin C Inhibits Visceral Adipocyte Hypertrophy and Lowers Blood Glucose Levels in High-Fat-Diet-Induced Obese C57BL/6J Mice. Biomedical Science Letters 24:4, pages 311-318.
Crossref
Peter Arner, Paul Petrus, David Esteve, Anne Boulomié, Erik Näslund, Anders Thorell, Hui Gao, Ingrid Dahlman & Mikael Rydén. (2018) Screening of potential adipokines identifies S100A4 as a marker of pernicious adipose tissue and insulin resistance. International Journal of Obesity 42:12, pages 2047-2056.
Crossref
Lars-Georg Hersoug, Peter Møller & Steffen Loft. (2018) Role of microbiota-derived lipopolysaccharide in adipose tissue inflammation, adipocyte size and pyroptosis during obesity. Nutrition Research Reviews 31:2, pages 153-163.
Crossref
Ahmad Zulkifli Mohd Rafie, Amir Syahir, Wan Amir Nizam Wan Ahmad, Mohd Zulkifli Mustafa & Abdul Razak Mariatulqabtiah. (2018) Supplementation of Stingless Bee Honey from Heterotrigona itama Improves Antiobesity Parameters in High-Fat Diet Induced Obese Rat Model . Evidence-Based Complementary and Alternative Medicine 2018, pages 1-10.
Crossref
Ann Hammarstedt, Silvia Gogg, Shahram Hedjazifar, Annika Nerstedt & Ulf Smith. (2018) Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity. Physiological Reviews 98:4, pages 1911-1941.
Crossref
Qi YuRuihan LiuLijuan HanGuangwei ZhangHua GuanQi PanSiwang WangEnqi Liu. (2018) Dietary restriction slightly affects glucose homeostasis and delays plasma cholesterol removal in rabbits with dietary lipid lowering. Applied Physiology, Nutrition, and Metabolism 43:10, pages 996-1002.
Crossref
Nathan Denton, Katherine E. Pinnick & Fredrik Karpe. (2018) Cartilage oligomeric matrix protein is differentially expressed in human subcutaneous adipose tissue and regulates adipogenesis. Molecular Metabolism 16, pages 172-179.
Crossref
Alberto Francisco Rubio-Guerra, Daniel Rabindranath Benítez-Maldonado, José Juan Lozano-Nuevo, Karla Corina Arana-Pazos, Saul Huerta-Ramirez & Jorge Luis Narváez-Rivera. (2018) Correlación entre el grosor de la grasa epicárdica y los marcadores bioquímicos de riesgo metabólico. Medicina Clínica 151:6, pages 236-238.
Crossref
Alberto Francisco Rubio-Guerra, Daniel Rabindranath Benítez-Maldonado, José Juan Lozano-Nuevo, Karla Corina Arana-Pazos, Saul Huerta-Ramirez & Jorge Luis Narváez-Rivera. (2018) Correlation between epicardial fat thickness and biochemical markers of metabolic risk. Medicina Clínica (English Edition) 151:6, pages 236-238.
Crossref
Karin G. Stenkula & Charlotte Erlanson-Albertsson. (2018) Adipose cell size: importance in health and disease. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 315:2, pages R284-R295.
Crossref
A Akshayavardhani & Pooja Pratheesh. (2018) An Insight on Selective Signaling Pathways Linking Obesity and Cancer. SBV Journal of Basic, Clinical and Applied Health Science 1:A3, pages 8-13.
Crossref
Ruben Rodriguez, Jacqueline N Minas, Jose Pablo Vazquez-Medina, Daisuke Nakano, David G Parkes, Akira Nishiyama & Rudy M Ortiz. (2018) Chronic AT1 blockade improves glucose homeostasis in obese OLETF rats. Journal of Endocrinology 237:3, pages 271-284.
Crossref
Xiaoying He, Hongyu Guan, Weiwei Liang, Zhimin Huang, Lijuan Xu, Pengyuan Zhang, Fen Xu & Yanbing Li. (2018) Exendin-4 modifies adipogenesis of human adipose-derived stromal cells isolated from omentum through multiple mechanisms. International Journal of Obesity 42:5, pages 1051-1061.
Crossref
Raquel Franco Leal, Lívia Bitencourt Pascoal, Francesca Aparecida Ramos da Silva & Bruno Lima Rodrigues. 2018. Adipose Tissue. Adipose Tissue.
Aleksandra Tarasiuk, Paula Mosińska & Jakub Fichna. (2018) The mechanisms linking obesity to colon cancer: An overview. Obesity Research & Clinical Practice 12:3, pages 251-259.
Crossref
Geneviève B. Marchand, Anne-Marie Carreau, Sofia Laforest, Julie-Anne Côté, Marleen Daris, Katherine Cianflone, Cornelia Prehn, Jerzy Adamski & André Tchernof. (2018) Circulating steroid levels as correlates of adipose tissue phenotype in premenopausal women. Hormone Molecular Biology and Clinical Investigation 34:1.
Crossref
A. Ishaq, J. Schröder, N. Edwards, T. von Zglinicki & Gabriele Saretzki. (2017) Dietary Restriction Ameliorates Age-Related Increase in DNA Damage, Senescence and Inflammation in Mouse Adipose Tissuey. The journal of nutrition, health & aging 22:4, pages 555-561.
Crossref
Diana Vargas, Carolina López, Edward Acero, Edgar Benitez, Angélica Wintaco, Jaime Camacho, Marisol Carreño, Juan Umaña, Daniela Jimenez, Said Díaz & Fernando Lizcano. (2018) Thermogenic capacity of human periaortic adipose tissue is transformed by body weight. PLOS ONE 13:3, pages e0194269.
Crossref
F. Haczeyni, K. S. Bell-Anderson & G. C. Farrell. (2018) Causes and mechanisms of adipocyte enlargement and adipose expansion. Obesity Reviews 19:3, pages 406-420.
Crossref
Sofia Laforest, Mélissa Pelletier, Andréanne Michaud, Marleen Daris, Justine Descamps, Denis Soulet, Michael D. Jensen & André Tchernof. (2018) Histomorphometric analyses of human adipose tissues using intact, flash-frozen samples. Histochemistry and Cell Biology 149:3, pages 209-218.
Crossref
Soon Shik Shin & Michung Yoon. (2018) Korean red ginseng ( Panax ginseng ) inhibits obesity and improves lipid metabolism in high fat diet-fed castrated mice. Journal of Ethnopharmacology 210, pages 80-87.
Crossref
Thierry Chénard, Frédéric Guénard, Marie-Claude Vohl, André Carpentier, André Tchernof & Rafael J. Najmanovich. (2017) Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes. BMC Systems Biology 11:1.
Crossref
Henry Thompson, John McGinley, Elizabeth Neil & Mark Brick. (2017) Beneficial Effects of Common Bean on Adiposity and Lipid Metabolism. Nutrients 9:9, pages 998.
Crossref
Jennifer Labrecque, Sofia Laforest, Andréanne Michaud, Laurent Biertho & André Tchernof. (2017) Impact of Bariatric Surgery on White Adipose Tissue Inflammation. Canadian Journal of Diabetes 41:4, pages 407-417.
Crossref
Miriam A. Bredella, Kalypso Karastergiou, Stijn A. Bos, Anu V. Gerweck, Martin Torriani, Susan K. Fried & Karen K. Miller. (2017) GH administration decreases subcutaneous abdominal adipocyte size in men with abdominal obesity. Growth Hormone & IGF Research 35, pages 17-20.
Crossref
Roel G. Vink, Nadia J. Roumans, Birgitta W. van der Kolk, Parastoo Fazelzadeh, Mark V. Boekschoten, Edwin C. Mariman & Marleen A. van Baak. (2017) Adipose Tissue Meal-Derived Fatty Acid Uptake Before and After Diet-Induced Weight Loss in Adults with Overweight and Obesity. Obesity 25:8, pages 1391-1399.
Crossref
Sean H.P.P. Roerink, Margreet A.E.M. Wagenmakers, Johan F. Langenhuijsen, Dov B. Ballak, Hanne M.M. Rooijackers, Frank C. d'Ancona, François M. van Dielen, Jan W.A. Smit, Theo S. Plantinga, Romana T. Netea-Maier & Ad R.M.M. Hermus. (2017) Increased Adipocyte Size, Macrophage Infiltration, and Adverse Local Adipokine Profile in Perirenal Fat in Cushing's Syndrome. Obesity 25:8, pages 1369-1374.
Crossref
Yulia Haim, Matthias Blüher, Daniel Konrad, Nir Goldstein, Nora Klöting, Ilana Harman-Boehm, Boris Kirshtein, Doron Ginsberg, Tanya Tarnovscki, Yftach Gepner, Iris Shai & Assaf Rudich. (2017) ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype. Molecular Metabolism 6:7, pages 725-736.
Crossref
Emilie PastelLaura J. McCullochRebecca WardShivam JoshiKim M. GoodingAngela C. ShoreKatarina Kos. (2017) GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction. Clinical Science 131:5, pages 343-353.
Crossref
Jessica Murphy, Grégory Moullec & Sylvia Santosa. (2017) Factors associated with adipocyte size reduction after weight loss interventions for overweight and obesity: a systematic review and meta-regression. Metabolism 67, pages 31-40.
Crossref
Ioannis Akoumianakis, Nadia Akawi & Charalambos Antoniades. (2017) Exploring the Crosstalk between Adipose Tissue and the Cardiovascular System. Korean Circulation Journal 47:5, pages 670.
Crossref
Johan Hoffstedt, Daniel P. Andersson, Daniel Eriksson Hogling, Jakob Theorell, Erik Näslund, Anders Thorell, Anna Ehrlund, Mikael Rydén & Peter Arner. (2017) Long-term Protective Changes in Adipose Tissue After Gastric Bypass. Diabetes Care 40:1, pages 77-84.
Crossref
Jun Shi, Manshu Yu & Meixiao Sheng. (2017) Angiogenesis and Inflammation in Peritoneal Dialysis: The Role of Adipocytes. Kidney and Blood Pressure Research 42:2, pages 209-219.
Crossref
A. O. Joaquim, C. P. Coelho, P. Dias Motta, L. F. Fel�cio, E. F. Bondan, E. Teodorov, M. F. M. Martins, T. B. Kirsten, L. V. Bonamin & M. M. Bernardi. (2017) Maternal food restriction in rats of the F0 generation increases retroperitoneal fat, the number and size of adipocytes and induces periventricular astrogliosis in female F1 and male F2 generations. Reproduction, Fertility and Development 29:7, pages 1340.
Crossref
Mohamed Fouad Mansour, Chon-Wai Jeremy Chan, Sofia Laforest, Alain Veilleux & André Tchernof. 2017. Adipose Tissue Biology. Adipose Tissue Biology 257 300 .
Atilla Engin. 2017. Obesity and Lipotoxicity. Obesity and Lipotoxicity 135 160 .
Susan K. Fried. (2017) Adipocyte size redux. Obesity 25:1, pages 15-15.
Crossref
Sofia Laforest, Andréanne Michaud, Gaétan Paris, Mélissa Pelletier, Hubert Vidal, Alain Géloën & André Tchernof. (2017) Comparative analysis of three human adipocyte size measurement methods and their relevance for cardiometabolic risk. Obesity 25:1, pages 122-131.
Crossref
Gonzalo Torres-Villalobos, Nashla Hamdan-Pérez, Andrea Díaz-Villaseñor, Armando R. Tovar, Ivan Torre-Villalvazo, Guillermo Ordaz-Nava, Sofía Morán-Ramos, Lilia G. Noriega, Braulio Martínez-Benítez, Alejandro López-Garibay, Samuel Torres-Landa, Juan C. Ceballos-Cantú, Claudia Tovar-Palacio, Elizabeth Figueroa-Juárez, Marcia Hiriart, Roberto Medina-Santillán, Carmen Castillo-Hernández & Nimbe Torres. (2016) Autologous subcutaneous adipose tissue transplants improve adipose tissue metabolism and reduce insulin resistance and fatty liver in diet-induced obesity rats. Physiological Reports 4:17, pages e12909.
Crossref
Michael Lenz, Nadia JT Roumans, Roel G Vink, Marleen A van Baak, Edwin CM Mariman, Ilja CW Arts, Theo M de Kok & Gökhan Ertaylan. (2016) Estimating real cell size distribution from cross-section microscopy imaging. Bioinformatics 32:17, pages i396-i404.
Crossref
Jane J. Lee, Alison Pedley, Udo Hoffmann, Joseph M. Massaro, John F. KeaneyJr.Jr., Ramachandran S. Vasan & Caroline S. Fox. (2016) Cross‐Sectional Associations of Computed Tomography (CT)‐Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study. Journal of the American Heart Association 5:3.
Crossref
Andréanne Michaud, Sofia Laforest, Mélissa Pelletier, Mélanie Nadeau, Serge Simard, Marleen Daris, Mathieu Lebœuf, Hubert Vidal, Alain Géloën & André Tchernof. (2016) Abdominal adipocyte populations in women with visceral obesity. European Journal of Endocrinology 174:2, pages 227-239.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.