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Critical Reviews in Clinical Laboratory Sciences Volume 30, 1993 - Issue 1
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Research Article

The Structure and Function of Central Nervous System Myelin

Karen A. Williams Research Institute, Hospital for Sick Children, Toronto, M5G 1X8
,
Charles M. Deber Research Institute, Hospital for Sick Children, Toronto, M5G 1X8; Department of Biochemistry, University of Toronto, Toronto, M5S 1A8, Ontario, Canada
&
O. A. Klrschner Neurology Research, Childrens Hospital, Boston, MA
Pages 29-64 | Published online: 27 Sep 2008

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Azra H Ligon, Mark A Pershouse, Samar Jasser, Yong-Kil Hong, Wk Alfred Yung & Peter A Steck. (1998) Differentially expressed gene products in glioblastoma cells suppressed for tumorigenicity. Journal of Neurovirology 4:2, pages 217-226.
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Leming Hang, Robert M. Nakamura & Raymond Tubbs. (1997) Current Concepts and Advances in Clinical Laboratory Testing for Autoimmune Diseases. Critical Reviews in Clinical Laboratory Sciences 34:3, pages 275-311.
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Roland Martin, Henry F. McFarland & J. M. Boggs. (1995) Immunological Aspects of Experimental Allergic Encephalomyelitis and Multiple Sclerosis. Critical Reviews in Clinical Laboratory Sciences 32:2, pages 121-182.
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Fairuz Maliha & Ashfaq Adnan. (2023) Mechanical Responses of a Single Myelin Layer: A Molecular Simulation Study. Biomolecules 13:10, pages 1525.
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Alexandra F. Putka, Juan P. Mato & Hayley S. McLoughlin. (2023) Myelinating Glia: Potential Therapeutic Targets in Polyglutamine Spinocerebellar Ataxias. Cells 12:4, pages 601.
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P.E. Bermejo Velasco, M.R. Blasco Quílez, A.J. Sánchez López & A. García Merino. (2011) Enfermedades desmielinizantes del sistema nervioso central. Concepto, clasificación y epidemiología. Medicine - Programa de Formación Médica Continuada Acreditado 10:75, pages 5065-5068.
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Younjin MinKai KristiansenJoan M. Boggs, Cynthia HustedJoseph A. ZasadzinskiJacob Israelachvili. (2009) Interaction forces and adhesion of supported myelin lipid bilayers modulated by myelin basic protein. Proceedings of the National Academy of Sciences 106:9, pages 3154-3159.
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Marjo S. van der Knaap & Jaap Valk. 2005. Magnetic Resonance of Myelination and Myelin Disorders. Magnetic Resonance of Myelination and Myelin Disorders 1 19 .
Benjamin Ohler, Karlheinz Graf, Richard Bragg, Travis Lemons, Robert Coe, Claude Genain, Jacob Israelachvili & Cynthia Husted. (2004) Role of lipid interactions in autoimmune demyelination. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1688:1, pages 10-17.
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Johannes M. Van Noort, Arianne C. van Sechel, Marianne J.B. van Stipdonk & Jeffrey J. Bajramovic. 1998. Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy, Proceedings of the 20th International Summer School of Brain Research. Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy, Proceedings of the 20th International Summer School of Brain Research 435 452 .
Shlomo Yehuda, Sharon Rabinovitz, David I Mostofsky, Moshe Huberman & Benjamin Sredni. (1997) Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. European Journal of Pharmacology 328:1, pages 23-29.
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Marco Vergelli, Valerie Pinet, Anne B. Vogt, Matthias Kalbus, Mauro Malnati, Paolo Riccio, Eric O. Long & Roland Martin. (2005) HLA‐DR‐restricted presentation of purified myelin basic protein is independent of intracellular processing. European Journal of Immunology 27:4, pages 941-951.
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Shlomo Yehuda, Sharon Rabinovitz & David I. Mostofsky. 1997. Handbook of Essential Fatty Acid Biology. Handbook of Essential Fatty Acid Biology 427 452 .
Marjo S. van der Knaap & Jacob ValkMarjo S. van der Knaap & Jacob Valk. 1995. Magnetic Resonance of Myelin, Myelination, and Myelin Disorders. Magnetic Resonance of Myelin, Myelination, and Myelin Disorders 1 17 .
Hyunglok Chung, Qi Ye, Ye-Jin Park, Zhongyuan Zuo, Oguz Kanca, Jung-Wan Mok, Sudhir Gopal Tattikota, Shenzhao Lu, Norbert Perrimon, Hyun Kyung Lee & Hugo Bellen. (2022) Very Long-Chain Fatty Acids Induce Glial-Derived Sphingosine-1-Phosphate Synthesis, Secretion, and Neuroinflammation. SSRN Electronic Journal.
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