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Research Article

P-Glycoprotein: Clinical Significance and Methods of Analysis

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Pages 221-264 | Published online: 27 Sep 2008

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Lale Kostakoglu & Stanley J. Goldsmith. (2001) Imaging Multidrug Resistance in Hematological Malignancies. Hematology 6:2, pages 111-124.
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Wim van de Vrie, Richard L. Marquet, Gerrit Stoter, Ernst A. De Bruijn & Alexander M. M. Eggermont. (1998) In Vivo Model Systems in P-Glycoprotein-Mediated Multidrug Resistance. Critical Reviews in Clinical Laboratory Sciences 35:1, pages 1-57.
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Articles from other publishers (27)

Erwin Danil Yulian, Filipus Dasawala & Nurjati Chairani Siregar. (2022) Association of P-glycoprotein expression and response to anthracycline-based neoadjuvant chemotherapy in locally advanced breast cancer. Medical Journal of Indonesia 31:1, pages 62-9.
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Tulin Ozkan, Yalda Hekmatshoar, Arzu Zeynep Karabay, Asli Koc, Buket Altinok Gunes, Aynur Karadag Gurel & Asuman Sunguroglu. (2021) Assessment of azithromycin as an anticancer agent for treatment of imatinib sensitive and resistant CML cells. Leukemia Research 102, pages 106523.
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Agnieszka Krawczenko, Aleksandra Bielawska-Pohl, Karolina Wojtowicz, Roksana Jura, Maria Paprocka, Elżbieta Wojdat, Urszula Kozłowska, Aleksandra Klimczak, Catherine Grillon, Claudine Kieda & Danuta Duś. (2017) Expression and activity of multidrug resistance proteins in mature endothelial cells and their precursors: A challenging correlation. PLOS ONE 12:2, pages e0172371.
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C. Knorr, J. O. Pelz, J. Göhl, W. Hohenberger & T. Meyer. (2010) Expression of Chemoresistance-Related Genes and Heat Shock Protein 72 in Hyperthermic Isolated Limb Perfusion of Malignant Melanoma: An Experimental Study. Journal of Oncology 2010, pages 1-7.
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Paula Yurie Tanaka & Edenilson Eduardo Calore. (2007) P-glycoprotein expression in non-Hodgkin's lymphomas of human immunodeficiency virus infected patients. Pathology - Research and Practice 203:1, pages 1-7.
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Gianfranco Tramonti, Ping Xie, Elisabeth I. Wallner, Farhad R. Danesh & Yashpal S. Kanwar. (2006) Expression and functional characteristics of tubular transporters: P-glycoprotein, PEPT1, and PEPT2 in renal mass reduction and diabetes. American Journal of Physiology-Renal Physiology 291:5, pages F972-F980.
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Aysun Sükan, Zeynep Yapar, Berksoy Şahin, Oǧuz Kara, A. Fuat Yapar, Salih Çetiner & Mustafa Kibar. (2004) 99mTc tetrofosmin scintigraphy in acute leukaemia: the relationship between marrow uptake of tetrofosmin and P-glycoprotein and chemotherapy response. Nuclear Medicine Communications 25:8, pages 777-785.
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Yuri N. Korystov, Natalia V. Ermakova, Ludmila N. Kublik, Maria Kh. Levitman, Vera V. Shaposhnikova, Vladimir A. Mosin, Viktor A. Drinyaev, Elena B. Kruglyak, Tamara S. Novik & Tatiana S. Sterlina. (2004) Avermectins inhibit multidrug resistance of tumor cells. European Journal of Pharmacology 493:1-3, pages 57-64.
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Shona S. Pendse, David M. Briscoe & Markus H. Frank. (2003) P-glycoprotein and alloimmune T-cell activation. Clinical and Applied Immunology Reviews 4:1, pages 3-14.
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Patrick Kwan, Graeme J. Sills, Elaine Butler, Timothy W. Gant, Brian S. Meldrum & Martin J. Brodie. (2002) Regional Expression of Multidrug Resistance Genes in Genetically Epilepsy‐prone Rat Brain after a Single Audiogenic Seizure. Epilepsia 43:11, pages 1318-1323.
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Graeme J. Sills, Patrick Kwan, Elaine Butler, Elizabeth C.M. de Lange, Dirk-Jan van den Berg & Martin J. Brodie. (2002) P-glycoprotein-mediated efflux of antiepileptic drugs: preliminary studies in mdr1a knockout mice. Epilepsy & Behavior 3:5, pages 427-432.
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Adriana M Doi, Earnestine Holmes & Kevin M Kleinow. (2001) P-glycoprotein in the catfish intestine: inducibility by xenobiotics and functional properties. Aquatic Toxicology 55:3-4, pages 157-170.
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Ian F. Faneyte, Petra M.P. Kristel & Marc J. van de Vijver. (2001) DeterminingMDR1/P-glycoprotein expression in breast cancer. International Journal of Cancer 93:1, pages 114-122.
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S Bard. (2000) Multixenobiotic resistance as a cellular defense mechanism in aquatic organisms. Aquatic Toxicology 48:4, pages 357-389.
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Hiroyuki Kobayashi, Yuzuru Takemura, Yohko Kawai, Hayato Miyachi, Masaki Kawabata, Takuya Matsumura, Takuya Yamashita, Shigehisa Mori, Kenichi Furihata, Shigetaka Shimodaira, Kazuo Motoyoshi, Tomomitsu Hotta, Susumu Sekiguchi, Yasuhiko Ando & Kiyoaki Watanabe. (2000) Competitive reverse transcription?polymerase chain reaction assay for quantification of human multidrug resistance 1 (MDR1 ) gene expression in fresh leukemic cells. Journal of Laboratory and Clinical Medicine 135:2, pages 199-209.
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C. Dhooge, B. De Moerloose, G. Laureys, J. Kint, A. Ferster, D. De Bacquer, J. Philippe & Y. Benoit. (2001) P‐glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia: results of a 6‐year prospective study. British Journal of Haematology 105:3, pages 676-683.
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Van Der Heyden, Highley, De Bruijn, Tjaden, Reeuwijk, Van Slooten, Van Oosterom & Maes. (1999) Pharmacokinetics and bioavailability of oral 5′-deoxy-5-fluorouridine in cancer patients. British Journal of Clinical Pharmacology 47:4, pages 351-356.
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John M. Martin, Stephen R. Madigosky, Zhe-ming Gu, Dawei Zhou, Jinn Wu & Jerry L. McLaughlin. (1998) Chemical Defense in the Zebra Swallowtail Butterfly, Eurytides marcellus , Involving Annonaceous Acetogenins . Journal of Natural Products 62:1, pages 2-4.
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Catharina Dhooge & Barbara De Moerloose. 1999. Drug Resistance in Leukemia and Lymphoma III. Drug Resistance in Leukemia and Lymphoma III 11 19 .
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B. J. Trock, F. Leonessa & R. Clarke. (1997) Multidrug Resistance in Breast Cancer: a Meta-analysis of MDR1/gp170 Expression and Its Possible Functional Significance. JNCI Journal of the National Cancer Institute 89:13, pages 917-931.
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Nicholas H. Oberlies, Ching-jer Chang & Jerry L. McLaughlin. (1997) Structure−Activity Relationships of Diverse Annonaceous Acetogenins against Multidrug Resistant Human Mammary Adenocarcinoma (MCF-7/Adr) Cells. Journal of Medicinal Chemistry 40:13, pages 2102-2106.
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Nicholas H. Oberlies, Vicki L. Croy, Marietta L. Harrison & Jerry L. McLaughlin. (1997) The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells. Cancer Letters 115:1, pages 73-79.
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E. Moran, I. Cleary, A.M. Larkin, R. Nic Amhlaoibh, A. Masterson, R.J. Scheper, M.A. Izquierdo, M. Center, F. O'Sullivan & M. Clynes. (1997) Co-expression of MDR-associated markers, including P-170, MRP and LRP and cytoskeletal proteins, in three resistant variants of the human ovarian carcinoma cell line, OAW42. European Journal of Cancer 33:4, pages 652-660.
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Hiroyuki Kobayashi, Yuzuru Takemura, Hayato Miyachi, Masaki Kawabata, Shigehisa Mori, Yohko Kawai, Kenichi Furihata, Susumu Sekiguchi & Kiyoaki Watanabe. (1997) Quantitative analysis of human multidrug resistance 1 (MDR1) gene expression by nonisotopic competitive reverse transcriptase polymerase chain reaction assay. Journal of Clinical Laboratory Analysis 11:5, pages 258-266.
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Mary W. Davey, Rebecca M. Hargrave & Ross A. Davey. (1996) Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells. Leukemia Research 20:8, pages 657-664.
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