Citations (68)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
John H Rex & Sevtap Arikan. (2002) New agents for the treatment of systemic fungal infections – current status. Expert Opinion on Emerging Drugs 7:1, pages 3-32.
Read now
Read now
A. S. Kantarcioglu & A. Yücel. (2002) A flucytosine-resistant Cryptococcus neoformans (serotype D) strain isolated in Turkey from cutaneous lesions. Medical Mycology 40:5, pages 519-523.
Read now
Read now
Sevtap Arikan & John H Rex. (2000) New agents for treatment of systemic fungal infections. Emerging Drugs 5:2, pages 135-160.
Read now
Read now
MaryBeth Frosco & John F Barrett. (1998) Importance of antifungal drug-resistance: clinical significance and need for novel therapy. Expert Opinion on Investigational Drugs 7:2, pages 175-198.
Read now
Read now
J.N. Galgiani, M.G. Rinaldi, A.M. Polak & M.A. Pfaller. (1992) Standardization of antifungal susceptibility testing. Journal of Medical and Veterinary Mycology 30:sup1, pages 213-224.
Read now
Read now
W.L. Whelan & K.J. Kwon-Chung. (1988) Auxotrophic heterozygosities and the ploidy of Candida parapsilosis and Candida krusei. Journal of Medical and Veterinary Mycology 26:3, pages 163-171.
Read now
Read now
Articles from other publishers (62)
Romain Durand, Jordan Jalbert-Ross, Anna Fijarczyk, Alexandre K. Dubé & Christian R. Landry. (2023) Cross-feeding affects the target of resistance evolution to an antifungal drug. PLOS Genetics 19:10, pages e1011002.
Crossref
Crossref
Liu-liu Sun, Hao Li, Tian-hua Yan, Yong-bing Cao, Yuan-ying Jiang & Feng Yang. (2023) Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis. Frontiers in Microbiology 14.
Crossref
Crossref
Hengyu Deng, Jialin Song, Yemei Huang, Chen Yang, Xuelei Zang, Yangyu Zhou, Hongli Li, Bin Dai & Xinying Xue. (2023) Combating increased antifungal drug resistance in <italic>Cryptococcus</italic>, what should we do in the future?. Acta Biochimica et Biophysica Sinica.
Crossref
Crossref
Thomas R Rogers, Paul E Verweij, Mariana Castanheira, Eric Dannaoui, P Lewis White, Maiken Cavling Arendrup, M C Arendrup, S Arikan-Akdagli, F Barchiesi, Jochem Buil, M Castanheira, E Chryssanthou, N Friberg, J Guinea, P Hamal, Ingibjorg Hilmarsdottir, N Klimko, O Kurzai, K Lagrou, C Lass-Flörl, T Matos, J Meletiadis, C Moore, K Muehlethaler & T R Rogers. (2022) Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications. Journal of Antimicrobial Chemotherapy 77:8, pages 2053-2073.
Crossref
Crossref
Yasemin Kaya, Banu Dokuzeylül, Utku Bakırel & Mehmet E. Or. (2022) Antifungal resistance and clinical significance in small animals. German Journal of Veterinary Research 2:2, pages 28-36.
Crossref
Crossref
Fatima Zohra Delma, Abdullah M. S. Al-Hatmi, Roger J. M. Brüggemann, Willem J. G. Melchers, Sybren de Hoog, Paul E. Verweij & Jochem B. Buil. (2021) Molecular Mechanisms of 5-Fluorocytosine Resistance in Yeasts and Filamentous Fungi. Journal of Fungi 7:11, pages 909.
Crossref
Crossref
Yun C. Chang, Ami Khanal Lamichhane, Hongyi Cai, Peter J. Walter, John E. Bennett & Kyung J. Kwon-Chung. (2021) Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci. Nature Communications 12:1.
Crossref
Crossref
Liza C. Loza & Tamara L. Doering. 2021. Comprehensive Glycoscience. Comprehensive Glycoscience
479
506
.
Mónica Galocha, Inês Vieira Costa & Miguel Cacho Teixeira. (2020) Carrier-Mediated Drug Uptake in Fungal Pathogens. Genes 11:11, pages 1324.
Crossref
Crossref
Saman Nematollahi & Veronica Dioverti‐Prono. (2020) Cryptococcal infection in haematologic malignancies and haematopoietic stem cell transplantation. Mycoses 63:10, pages 1033-1046.
Crossref
Crossref
Lukas Birštonas, Alex Dallemulle, Manuel S. López-Berges, Ilse D. Jacobsen, Martin Offterdinger, Beate Abt, Maria Straßburger, Ingo Bauer, Oliver Schmidt, Bettina Sarg, Herbert Lindner, Hubertus Haas & Fabio Gsaller. (2020) Multiplex Genetic Engineering Exploiting Pyrimidine Salvage Pathway-Based Endogenous Counterselectable Markers. mBio 11:2.
Crossref
Crossref
R. Blake Billmyre, Shelly Applen Clancey, Lucy X. Li, Tamara L. Doering & Joseph Heitman. (2020) 5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus. Nature Communications 11:1.
Crossref
Crossref
Kiem Vu, George R ThompsonIIIIII, Chandler C Roe, Jane E Sykes, Elizabeth M Dreibe, Shawn R Lockhart, Wieland Meyer, David M Engelthaler & Angie Gelli. (2018) Flucytosine resistance in Cryptococcus gattii is indirectly mediated by the FCY2-FCY1-FUR1 pathway. Medical Mycology 56:7, pages 857-867.
Crossref
Crossref
Fabio Gsaller, Takanori Furukawa, Paul D. Carr, Bharat Rash, Christoph Jöchl, Margherita Bertuzzi, Elaine M. Bignell & Michael J. Bromley. (2018) Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy 62:6.
Crossref
Crossref
Xi-Ren Deng, Fu-Cai Wang, Mu-Ying Ying, Jie-Yu Zhang, Ying Ying, Ling-Bing Zeng, Xue-Fei Hu, Ke Wang, Qiong Liu & Xiao-Tian Huang. (2017) Characterization of the Same Mutations in FCA1 Gene Associated With 5-FC Resistance of Candida albicans. Jundishapur Journal of Microbiology 10:8.
Crossref
Crossref
Liliana Scorzoni, Ana C. A. de Paula e Silva, Caroline M. Marcos, Patrícia A. Assato, Wanessa C. M. A. de Melo, Haroldo C. de Oliveira, Caroline B. Costa-Orlandi, Maria J. S. Mendes-Giannini & Ana M. Fusco-Almeida. (2017) Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis. Frontiers in Microbiology 08.
Crossref
Crossref
Kimberly E. Hanson, Jelena Catania, Barbara D. Alexander & John R. Perfect. 2017. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance
1119
1140
.
Robert A. Akins & Jack D. Sobel. 2017. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance
429
475
.
Jyotsna Chandra & Mahmoud A. Ghannoum. 2017. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance
407
413
.
Jose A Reales-Calderón, Gloria Molero, Concha Gil & José L Martínez. (2016) The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies. Future Medicinal Chemistry 8:12, pages 1503-1520.
Crossref
Crossref
Uh Jin KimSook-In Jung. (2015) Invasive Fungal Infections in the Era of Antifungal Resistance. Korean Journal of Medicine 88:5, pages 518.
Crossref
Crossref
H.R. Ashbee & M.H. Gilleece. 2014. Handbook of Pharmacogenomics and Stratified Medicine. Handbook of Pharmacogenomics and Stratified Medicine
879
900
.
A. Espinel-Ingroff, A. Chowdhary, M. Cuenca-Estrella, A. Fothergill, J. Fuller, F. Hagen, N. Govender, J. Guarro, E. Johnson, C. Lass-Flörl, S. R. Lockhart, M. A. Martins, J. F. Meis, M. S. C. Melhem, L. Ostrosky-Zeichner, T. Pelaez, M. A. Pfaller, W. A. Schell, L. Trilles, S. Kidd & J. Turnidge. (2012) Cryptococcus neoformans-Cryptococcus gattii Species Complex: an International Study of Wild-Type Susceptibility Endpoint Distributions and Epidemiological Cutoff Values for Amphotericin B and Flucytosine. Antimicrobial Agents and Chemotherapy 56:6, pages 3107-3113.
Crossref
Crossref
Min-Hee Song, Jang-Won Lee, Min Su Kim, Ja-Kyung Yoon, Theodore C. White, Anna Floyd, Joseph Heitman, Anna K. Strain, Judith N. Nielsen, Kirsten Nielsen & Yong-Sun Bahn. (2012) A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans. Eukaryotic Cell 11:1, pages 53-67.
Crossref
Crossref
Edmond J. Byrnes, Wenjun Li, Ping Ren, Yonathan Lewit, Kerstin Voelz, James A. Fraser, Fred S. Dietrich, Robin C. May, Sudha Chatuverdi, Vishnu Chatuverdi & Joseph Heitman. (2011) A Diverse Population of Cryptococcus gattii Molecular Type VGIII in Southern Californian HIV/AIDS Patients. PLoS Pathogens 7:9, pages e1002205.
Crossref
Crossref
Thomas D. Edlind. 2011. Molecular Microbiology. Molecular Microbiology
677
684
.
M. A. Pfaller, J. K. Lodge & M. A. Ghannoum. 2010. Cryptococcus. Cryptococcus
203
216
.
Thomas D. Edlind & Santosh K. Katiyar. (2010)
Mutational Analysis of Flucytosine Resistance in
Candida glabrata
. Antimicrobial Agents and Chemotherapy 54:11, pages 4733-4738.
Crossref
Crossref
Sevtap Arikan & John H. Rex. 2010. Topley & Wilson's Microbiology and Microbial Infections. Topley & Wilson's Microbiology and Microbial Infections.
Sélène Ferrari & Dominique Sanglard. 2010. Pathogenic Yeasts. Pathogenic Yeasts
327
358
.
Rong Zhao, Wen Bin, YouJiang Diao, Jian Yang, Tao Liu, JunPing Peng & Qi Jin. (2009) Global transcriptional profiles of Trichophyton rubrum in response to Flucytosine. Science in China Series C: Life Sciences 52:12, pages 1173-1185.
Crossref
Crossref
Pranab Mukherjee & Mingyue Wang. 2009. Antifungal Therapy. Antifungal Therapy
63
86
.
Richard Drew. 2009. Antifungal Therapy. Antifungal Therapy
184
198
.
Martine Florent, Thierry Noël, Gwenaël Ruprich-Robert, Bruno Da Silva, Valérie Fitton-Ouhabi, Christiane Chastin, Nicolas Papon & Florence Chapeland-Leclerc. (2009)
Nonsense and Missense Mutations in
FCY2
and
FCY1
Genes Are Responsible for Flucytosine Resistance and Flucytosine-Fluconazole Cross-Resistance in Clinical Isolates of
Candida lusitaniae
. Antimicrobial Agents and Chemotherapy 53:7, pages 2982-2990.
Crossref
Crossref
Kimberly E. Hanson, Barbara D. Alexander & John Perfect. 2009. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance
967
985
.
Jyotsna Chandra, Sotohy Mohammad & Mahmoud A. Ghannoum. 2009. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance
313
326
.
John P. Paluszynski, Roland Klassen & Friedhelm Meinhardt. (2008) Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast. Microbiology 154:10, pages 3154-3164.
Crossref
Crossref
Luis Ostrosky-Zeichner & John H. Rex. 2008. Critical Care Medicine. Critical Care Medicine
1089
1109
.
Beth A. Arthington-Skaggs & John H. Rex. 2008. Antimicrobial Resistance and Implications for the Twenty-First Century. Antimicrobial Resistance and Implications for the Twenty-First Century
325
369
.
Thomas D. Edlind. 2007. Evolutionary Biology of Bacterial and Fungal Pathogens. Evolutionary Biology of Bacterial and Fungal Pathogens
297
306
.
Marybeth A. Maligie & Claude P. Selitrennikoff. (2005)
Cryptococcus neoformans
Resistance to Echinocandins: (1,3)β-Glucan Synthase Activity Is Sensitive to Echinocandins
. Antimicrobial Agents and Chemotherapy 49:7, pages 2851-2856.
Crossref
Crossref
P. Brian Smith, William J. Steinbach & Daniel K. BenjaminJr.Jr.. (2005) Invasive Candida infections in the neonate. Drug Resistance Updates 8:3, pages 147-162.
Crossref
Crossref
Xiaomin Zhao, Claude Pujol, David R. Soll & Lois L. Hoyer. (2003) Allelic variation in the contiguous loci encoding Candida albicans
ALS5, ALS1 and ALS9. Microbiology 149:10, pages 2947-2960.
Crossref
Crossref
H. Vanden Bossche, M. Engelen & F. Rochette. (2003) Antifungal agents of use in animal health - chemical, biochemical and pharmacological aspects. Journal of Veterinary Pharmacology and Therapeutics 26:1, pages 5-29.
Crossref
Crossref
Sofia Perea & Thomas F. Patterson. (2002) Antifungal Resistance in Pathogenic Fungi. Clinical Infectious Diseases 35:9, pages 1073-1080.
Crossref
Crossref
Kenneth S. McKeegan, M.Ines Borges-Walmsley & Adrian R. Walmsley. (2002) Microbial and viral drug resistance mechanisms. Trends in Microbiology 10:10, pages s8-s14.
Crossref
Crossref
Dimitrios P Kontoyiannis & Russell E Lewis. (2002) Antifungal drug resistance of pathogenic fungi. The Lancet 359:9312, pages 1135-1144.
Crossref
Crossref
Maher M. Balkis, Steven D. Leidich, Pranab K. Mukherjee & Mahmoud A. Ghannoum. (2002) Mechanisms of Fungal Resistance. Drugs 62:7, pages 1025-1040.
Crossref
Crossref
Jennifer K. Lodge & John R. Perfect. 2002. Pathogen Genomics. Pathogen Genomics
197
214
.
Michael E. Klepser. (2012)
Antifungal Resistance Among
Candida
Species
. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 21:8P2.
Crossref
Crossref
Mahmoud A. Ghannoum & Louis B. Rice. (1999) Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance. Clinical Microbiology Reviews 12:4, pages 501-517.
Crossref
Crossref
Lauren D. Stegman, Alnawaz Rehemtulla, Bradley Beattie, Els Kievit, Theodore S. Lawrence, Ronald G. Blasberg, Juri G. Tjuvajev & Brian D. Ross. (1999)
Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with
in vivo
magnetic resonance spectroscopy
. Proceedings of the National Academy of Sciences 96:17, pages 9821-9826.
Crossref
Crossref
John R. Perfect & Gary M. Cox. (1999) Drug resistance in Cryptococcus neoformans. Drug Resistance Updates 2:4, pages 259-269.
Crossref
Crossref
Arturo Casadevall & John R. Perfect. 1998. Cryptococcus neoformans. Cryptococcus neoformans
115
144
.
Arturo Casadevall & John R. Perfect. 1998. Cryptococcus neoformans. Cryptococcus neoformans
457
518
.
Theodore C. White, Kieren A. Marr & Raleigh A. Bowden. (1998) Clinical, Cellular, and Molecular Factors That Contribute to Antifungal Drug Resistance. Clinical Microbiology Reviews 11:2, pages 382-402.
Crossref
Crossref
T C White. (1997) The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans. Antimicrobial Agents and Chemotherapy 41:7, pages 1488-1494.
Crossref
Crossref
J. PLA, C. GIL, L. MONTEOLIVA, F. NAVARRO-GARCÍA, M. SÁNCHEZ & C. NOMBELA. (1996) UnderstandingCandida albicans at the Molecular Level. Yeast 12:16, pages 1677-1702.
Crossref
Crossref
M B KurtzG AbruzzoA FlatteryK BartizalJ A MarrinanW LiJ MilliganK NollstadtC M Douglas. (1996) Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies. Infection and Immunity 64:8, pages 3244-3251.
Crossref
Crossref
Frank C. Odds. (1996) Resistance of clinically important yeasts to antifungal agents. International Journal of Antimicrobial Agents 6:3, pages 145-147.
Crossref
Crossref
R. T. M. Poulter. 1991. Candida Albicans. Candida Albicans
188
197
.
R. T. M. Poulter. 1991. Candida Albicans. Candida Albicans
164
187
.