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Critical Reviews in Toxicology Volume 46, 2016 - Issue 1
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Review Articles

Illustrative case using the RISK21 roadmap and matrix: prioritization for evaluation of chemicals found in drinking water

Douglas C. WolfSyngenta Crop Protection LLC, Greensboro, NC, USA
,
Ammie BachmanExxonMobil Biomedical Sciences, Inc., Annandale, NJ, USA
,
Gordon BarrettHealth Canada, Ottawa, Ontario, Canada
,
Cheryl BellinDuPont Haskell Global Centers for Health & Environmental Sciences, Newark, DE, USA
,
Jay I. GoodmanPharmcology & Toxicology, Michigan State University, East Lansing, MI, USA
,
Elke JensenDepartment of Biomedical & Clinical Sciences, University of Milan, Milan, Italy
,
Angelo MorettoDepartment of Biomedical & Clinical Sciences, University of Milan, Milan, Italy
,
Tami McMullinDow Corning Corporation, Midland, MI, USA
,
Timothy P. PastoorSyngenta Crop Protection LLC, Greensboro, NC, USA
,
Rita SchoenyUnited States Environmental Protection Agency, Washington, DC, USA
,
Brian SlezakDuPont Haskell Global Centers for Health & Environmental Sciences, Newark, DE, USA
,
Korinna WendDepartment of Orthopaedic Surgery, UCLA and Orthopaedic Hospital, Los Angeles, CA, USA;Orthopaedic Hospital Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
&
Michelle R. EmbryILSI Health and Environmental Sciences Institute, Washington, DC, USACorrespondence[email protected]
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Pages 43-53 | Received 10 Apr 2015, Accepted 11 Aug 2015, Published online: 09 Oct 2015

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Douglas C. Wolf & Michelle R. Embry. (2016) Response to letter to the editor from Chappelle, Spence, and Tury concerning Wolf et al. 2016: Illustrative case using the RISK21 roadmap and matrix: prioritization for evaluation of chemicals found in drinking water. 2016, Crit. Rev. Toxicol. Vol 46: 43–53. Critical Reviews in Toxicology 46:10, pages 913-914.
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Anne Harman Chappelle, Mark Spence & Bernard Tury. (2016) Letter to the editor RE: Wolf et al.. Critical Reviews in Toxicology 46:10, pages 911-912.
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Articles from other publishers (10)

Siti Soleha Ab Dullah, Mohd Redzwan Sabran, Ab Hamid Hasiah & Rozaini Abdullah. (2023) Risk assessment of aflatoxin B1 in herbal medicines and plant food supplements marketed in Malaysia using margin of exposure and RISK21 approaches. Genes and Environment 45:1.
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John Reginald Foster & Jeffery A. Engelhardt. 2023. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 : Safety Assessment Environmental Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 : Safety Assessment Environmental Toxicologic Pathology 567 615 .
Nikolai Chepelev, Alexandra S. Long, Marc Beal, Tara Barton‐Maclaren, George Johnson, Kerry L. Dearfield, Daniel J. Roberts, Jan van Benthem & Paul White. (2023) Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data. Environmental and Molecular Mutagenesis 64:1, pages 4-15.
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Mirjam Luijten, R. Corinne Sprong, Emiel Rorije & Leo T. M. van der Ven. (2022) Prioritization of chemicals in food for risk assessment by integrating exposure estimates and new approach methodologies: A next generation risk assessment case study. Frontiers in Toxicology 4.
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Pratibha Mistry, Elizabeth F. McInnes, Carol Beevers, Douglas Wolf, Richard A. Currie, Rejin Salimraj & Paul Parsons. (2021) An evaluation of carcinogenicity predictors from short-term and sub chronic repeat-dose studies of agrochemicals in rats: Opportunities to refine and reduce animal use. Toxicology Letters 351, pages 18-27.
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D. Krewski, M. E. Andersen, M. G. Tyshenko, K. Krishnan, T. Hartung, K. Boekelheide, J. F. Wambaugh, D. Jones, M. Whelan, R. Thomas, C. Yauk, T. Barton-Maclaren & I. Cote. (2019) Toxicity testing in the 21st century: progress in the past decade and future perspectives. Archives of Toxicology 94:1, pages 1-58.
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Marissa B. Kosnik & David M. Reif. (2019) Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases. Toxicology and Applied Pharmacology 379, pages 114674.
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Anne Marie Gannon, Marjory Moreau, Reza Farmahin, Russell S. Thomas, Tara S. Barton-Maclaren, Andy Nong, Ivan Curran & Carole L. Yauk. (2019) Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment. Food and Chemical Toxicology 131, pages 110581.
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Salmaan H. Inayat-Hussain, Masao Fukumura, A. Muiz Aziz, Chai Meng Jin, Low Wei Jin, Rolando Garcia-Milian, Vasilis Vasiliou & Nicole C. Deziel. (2018) Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment. Environment International 117, pages 348-358.
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Grace Patlewicz, John F. Wambaugh, Susan P. Felter, Ted W. Simon & Richard A. Becker. (2018) Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals. Computational Toxicology 7, pages 58-67.
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