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Research Article

Modification of Genotoxicity by Naturally Occurring Flavorings and Their Derivatives

Pages 127-146 | Published online: 25 Sep 2008

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Ren Shan, Kyoung-Jin Lee, Byoung-Mog Kwon & Chi-Ho Lee. (2005) Protein Binding Characteristics of 2′-Benzoyloxycinnamaldehyde. Drug Development and Industrial Pharmacy 31:6, pages 545-549.
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S. Santosh Kumar, K. I. Priyadarsini & K. B. Sainis. (2002) Free radical scavenging activity of vanillin and o-vanillin using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. Redox Report 7:1, pages 35-40.
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Christina E. Schwab, Wolfgang W. Huber, Wolfram Parzefall, Gerhard Hietsch, Fekadu Kassie, Rolf Schulte-Hermann & Siegfried Knasmüller. (2000) Search for Compounds That Inhibit the Genotoxic and Carcinogenic Effects of Heterocyclic Aromatic Amines. Critical Reviews in Toxicology 30:1, pages 1-69.
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Articles from other publishers (41)

Bolaji B. Oluremi, Paul M. Osamudiamen, Johnson A. Adeniji & Olapeju O. Aiyelaagbe. (2022) Anti-Measles Virus Activity of 4-Hydroxy-3-Methoxy Benzaldehyde (Vanillin) isolated from Xylopia aethiopica (Dunal) A. Rich. Scientific African, pages e01506.
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Shin Yen Chong, Hsin-Yi Chiang, Tzu-Hung Chen, Yi-Ju Liang & Yi-Chen Lo. (2019) Green tea extract promotes DNA repair in a yeast model. Scientific Reports 9:1.
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Hajer Ben Saad, Dorra Driss, Ibtissem Ben Amara, Ons Boudawara, Tahia Boudawara, Samia Ellouz Chaabouni, Khaled Mounir Zeghal & Ahmed Hakim. (2016) Altered hepatic mRNA expression of immune response-associated DNA damage in mice liver induced by potassium bromate: Protective role of vanillin. Environmental Toxicology 31:12, pages 1796-1807.
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Masayuki Kanki, Min Gi, Masaki Fujioka & Hideki Wanibuchi. (2016) Detection of non-genotoxic hepatocarcinogens and prediction of their mechanism of action in rats using gene marker sets. The Journal of Toxicological Sciences 41:2, pages 281-292.
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Ashgar Abbas, Halil Gökce & Semiha Bahçeli. (2016) Spectroscopic (vibrational, NMR and UV–vis.) and quantum chemical investigations on 4-hexyloxy-3-methoxybenzaldehyde. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 152, pages 596-607.
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Denis Velic, Anthony Couturier, Maria Ferreira, Amélie Rodrigue, Guy Poirier, Fabrice Fleury & Jean-Yves Masson. (2015) DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles’ Heel of Cancer. Biomolecules 5:4, pages 3204-3259.
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Jason S. Garcia & Raymond D. Harbison. 2015. Hamilton & Hardy's Industrial Toxicology. Hamilton & Hardy's Industrial Toxicology 445 490 .
Jienny Lee, Jae Youl Cho, Sang Yeol Lee, Kyung-Woo Lee, Jongsung Lee & Jae-Young Song. (2014) Vanillin protects human keratinocyte stem cells against Ultraviolet B irradiation. Food and Chemical Toxicology 63, pages 30-37.
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Juan Sun, Yong Yin, Gui-Hua Sheng, Zhi-Bo Yang & Hai-Liang Zhu. (2013) Synthesis, molecular modeling and structural characterization of vanillin derivatives as antimicrobial agents. Journal of Molecular Structure 1039, pages 214-218.
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Soumya Basu, Avishek Ganguly, Paramita Chakraborty, Rupashree Sen, Kaushik Banerjee, Mitali Chatterjee, Thomas Efferth & Soumitra Kumar Choudhuri. (2012) Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff’s base to overcome MDR in cancer. Biochimie 94:1, pages 166-183.
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Huang-Hui Chen, Wenchang Chiang, Jang-Yang Chang, Ya-Lin Chien, Ching-Kuo Lee, Ko-Jiunn Liu, Yen-Ting Cheng, Ting-Fang Chen, Yueh-Hsiung Kuo & Ching-Chuan Kuo. (2011) Antimutagenic Constituents of Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) with Potential Cancer Chemopreventive Activity . Journal of Agricultural and Food Chemistry 59:12, pages 6444-6452.
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Ghanya Al-Naqeb, Maznah Ismail, Gururaj Bagalkotkar & Hadiza Altine Adamu. (2010) Vanillin rich fraction regulates LDLR and HMGCR gene expression in HepG2 cells. Food Research International 43:10, pages 2437-2443.
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Lu Yu, Na Guo, Yi Yang, Xiuping Wu, Rizeng Meng, Junwen Fan, Fa Ge, Xuelin Wang, Jingbo Liu & Xuming Deng. (2009) Microarray analysis of p-anisaldehyde-induced transcriptome of Saccharomyces cerevisiae. Journal of Industrial Microbiology & Biotechnology 37:3, pages 313-322.
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M. Mišík, A. Nersesyan, W. Parzefall & S. Knasmüller. 2009. Epigenetics and Human Health. Epigenetics and Human Health 105 124 .
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Palayyan Saraswathy Benherlal & Chami Arumughan. (2008) Studies on modulation of DNA integrity in Fenton’s system by phytochemicals. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 648:1-2, pages 1-8.
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Hong Zheng, Zhi-Wu Chen, Lin Wang, Si-Ying Wang, Yu-Qian Yan, Ke Wu, Qin-Zhi Xu, Shi-Meng Zhang & Ping-Kun Zhou. (2008) Radioprotection of 4-hydroxy-3,5-dimethoxybenzaldehyde (VND3207) in culture cells is associated with minimizing DNA damage and activating Akt. European Journal of Pharmaceutical Sciences 33:1, pages 52-59.
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Dharmendra Kumar Maurya, Soumyakanti Adhikari, Cherupally Krishnan K. Nair & Thomas P.A. Devasagayam. (2007) DNA protective properties of vanillin against γ-radiation under different conditions: Possible mechanisms. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 634:1-2, pages 69-80.
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Yu-Qian Yan, Bo Zhang, Lin Wang, Yue-Hua Xie, Tao Peng, Bei Bai & Ping-Kun Zhou. (2007) Induction of apoptosis and autophagic cell death by the vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde is accompanied by the cleavage of DNA-PKcs and rapid destruction of c-Myc oncoprotein in HepG2 cells. Cancer Letters 252:2, pages 280-289.
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Audrey A. King, Daniel T. Shaughnessy, Kanae Mure, Joanna Leszczynska, William O. Ward, David M. Umbach, Zongli Xu, Danica Ducharme, Jack A. Taylor, David M. DeMarini & Catherine B. Klein. (2007) Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 616:1-2, pages 60-69.
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Soo-Yeon Kim, Kyoung-Jin Lee, Young-Hee Shin & Chi-Ho Lee. (2004) Physicochemical properties of 2′-benzoyloxycinnamaldehyde. International Journal of Pharmaceutics 287:1-2, pages 21-26.
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S. Santosh Kumar, K. Indira Priyadarsini & Krishna B. Sainis. (2003) Inhibition of Peroxynitrite-Mediated Reactions by Vanillin. Journal of Agricultural and Food Chemistry 52:1, pages 139-145.
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