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Original Article

Pulmonary Retention and Clearance of Inhaled Biopersistent Aerosol Particles: Data-Reducing Interpolation Models and Models of Physiologically Based Systems: - A Review of Recent Progress and Remaining Problems

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Pages 539-598 | Published online: 20 Mar 2010

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Kevin Dillon, Karin Jochims, Ursula Gerigk, Franz Jost, Hans Kobesen & Ruth Bialucha. (2020) No pathogenic responses in rat lung upon exposure to ground granulated blast furnace slag (GGBS). Inhalation Toxicology 32:1, pages 39-52.
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Walter Stinn, Ashok Teredesai, Erwin Anskeit, Klaus Rustemeier, Georg Schepers, Peter Schnell, Hans-Juergen Haussmann, Richard A. Carchman, Christopher R. E. Coggins & Wolf Reininghaus. (2005) Chronic Nose-only Inhalation Study in Rats, comparing Room-aged Sidestream Cigarette Smoke and Diesel Engine Exhaust. Inhalation Toxicology 17:11, pages 549-576.
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Domenico Vitarella, Owen Moss, David C. Dorman. (2000) PULMONARY CLEARANCE OF MANGANESE PHOSPHATE, MANGANESE SULFATE, AND MANGANESE TETRAOXIDE BY CD RATS FOLLOWING INTRATRACHEAL INSTILLATION. Inhalation Toxicology 12:10, pages 941-957.
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C. L. Tran, A. D. Jones, R. T. Cullen, K. Donaldson. (1999) MATHEMATICAL MODELING OF THE RETENTION AND CLEARANCE OF LOW-TOXICITY PARTICLES IN THE LUNG. Inhalation Toxicology 11:12, pages 1059-1076.
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Werner Stöber, FrederickJ. Miller & RogerO. McClellan. (1998) Requirements for a Credible Extrapolation Model Derived from Health Effects in Rats Exposed to Particulate Air Pollution: A Way to Minimize the Risks of Human Risk Assessment?. Applied Occupational and Environmental Hygiene 13:6, pages 421-431.
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Articles from other publishers (17)

Seyoung Kim, Daniel J. Fesenmeier, Sungwan Park, Sandra E. Torregrosa-Allen, Bennett D. Elzey & You-Yeon Won. (2022) Pulmonary Pharmacokinetics of Polymer Lung Surfactants Following Pharyngeal Administration in Mice. Biomacromolecules 23:6, pages 2471-2484.
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Helmut I. Padilla-Chavarría, Teobaldo R. C. Guizado & Andre S. Pimentel. (2015) Molecular dynamics of dibenz[a,h]anthracene and its metabolite interacting with lung surfactant phospholipid bilayers. Physical Chemistry Chemical Physics 17:32, pages 20912-20922.
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Jürgen Pauluhn. (2014) Derivation of occupational exposure levels (OELs) of Low-toxicity isometric biopersistent particles: how can the kinetic lung overload paradigm be used for improved inhalation toxicity study design and OEL-derivation?. Particle and Fibre Toxicology 11:1.
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Ndokiari Boisa, Nwabueze Elom, John R. Dean, Michael E. Deary, Graham Bird & Jane A. Entwistle. (2014) Development and application of an inhalation bioaccessibility method (IBM) for lead in the PM10 size fraction of soil. Environment International 70, pages 132-142.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 78 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 78 .
Jürgen Pauluhn. 2013. Nanomaterials. Nanomaterials 68 83 .
Katrin Burkart, Irene Nehls, Tin Win & Wilfried Endlicher. (2011) The carcinogenic risk and variability of particulate-bound polycyclic aromatic hydrocarbons with consideration of meteorological conditions. Air Quality, Atmosphere & Health 6:1, pages 27-38.
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Jürgen Pauluhn. (2011) Poorly soluble particulates: Searching for a unifying denominator of nanoparticles and fine particles for DNEL estimation. Toxicology 279:1-3, pages 176-188.
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Robert Sturm. (2010) Deposition and cellular interaction of cancer-inducing particles in the human respiratory tract: Theoretical approaches and experimental data. Thoracic Cancer 1:4, pages 141-152.
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Jürgen Pauluhn. (2010) Multi-walled carbon nanotubes (Baytubes®): Approach for derivation of occupational exposure limit. Regulatory Toxicology and Pharmacology 57:1, pages 78-89.
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Rajiv K. Saxena, M. Ian Gilmour, Mette C. Schladweiler, Michael McClure, Michael Hays & Urmila P. Kodavanti. (2009) Differential Pulmonary Retention of Diesel Exhaust Particles in Wistar Kyoto and Spontaneously Hypertensive Rats. Toxicological Sciences 111:2, pages 392-401.
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Jürgen Pauluhn. (2009) Pulmonary Toxicity and Fate of Agglomerated 10 and 40 nm Aluminum Oxyhydroxides following 4-Week Inhalation Exposure of Rats: Toxic Effects are Determined by Agglomerated, not Primary Particle Size. Toxicological Sciences 109:1, pages 152-167.
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Jürgen Pauluhn. (2009) Retrospective analysis of 4-week inhalation studies in rats with focus on fate and pulmonary toxicity of two nanosized aluminum oxyhydroxides (boehmite) and pigment-grade iron oxide (magnetite): The key metric of dose is particle mass and not particle surface area. Toxicology 259:3, pages 140-148.
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Robert Sturm. (2007) A computer model for the clearance of insoluble particles from the tracheobronchial tree of the human lung. Computers in Biology and Medicine 37:5, pages 680-690.
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Werner HofmannRobert Sturm. (2004) Stochastic Model of Particle Clearance in Human Bronchial Airways. Journal of Aerosol Medicine 17:1, pages 73-89.
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Roger McClellan. 2000. Particle-Lung Interactions. Particle-Lung Interactions 3 63 .

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