Citations (162)
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Read on this site (6)
U Gröber, J Reichrath, MF Holick & K Kisters. (2014) Vitamin K: an old vitamin in a new perspective. Dermato-Endocrinology 6:1.
Read now
Read now
Mamoru Igarashi, Yoshiko Yogiashi, Masatomo Mihara, Ichiro Takada, Hirochika Kitagawa & Shigeaki Kato. (2007) Vitamin K Induces Osteoblast Differentiation through Pregnane X Receptor-Mediated Transcriptional Control of the Msx2 Gene. Molecular and Cellular Biology 27:22, pages 7947-7954.
Read now
Read now
Thorsten Schinke, Marc D McKee, Riku Kiviranta & Gerard Karsenty. (1998) Trends in Molecular Medicine: Molecular determinants of arterial calcification. Annals of Medicine 30:6, pages 538-541.
Read now
Read now
K. R. Huckle, D. H. Hutson & P. A. Warburton. (1988) Elimination and Accumulation of the Rodenticide Flocoumafen in Rats Following Repeated Oral Administration. Xenobiotica 18:12, pages 1465-1479.
Read now
Read now
Kathryn E. McLane, Jed Fisher & K. Ramakrishnan. (1983) Reductive Drug Metabolism. Drug Metabolism Reviews 14:4, pages 741-799.
Read now
Read now
Yale Nemerson, Bruce Furie & Craig M. Jackson. (1980) Zymogens and Cofactors of Blood Coagulatio. Critical Reviews in Biochemistry 9:1, pages 45-85.
Read now
Read now
Articles from other publishers (156)
Shotaro Goto, Shuichi Setoguchi, Nami Nagata-Akaho, Kazuki Terada, Daisuke Watase, Hirofumi Yamakawa, Erina Toki, Mitsuhisa Koga, Kazuhisa Matsunaga, Yoshiharu Karube & Jiro Takata. (2020) Ester derivatives of phyllohydroquinone effectively deliver the active form of vitamin K1 topically, owing to their non-photosensitivity. European Journal of Pharmaceutical Sciences 155, pages 105519.
Crossref
Crossref
Yashu Chen, Qin Mu, Kai Hu, Mo Chen, Jifang Yang, Jigang Chen, Bijun Xie & Zhida Sun. (2018) Characterization of MK8(H2) from Rhodococcus sp. B7740 and Its Potential Antiglycation Capacity Measurements. Marine Drugs 16:10, pages 391.
Crossref
Crossref
Kotomi Nagahashi, Kazuo Umemura, Naohiro Kanayama & Takayuki Iwaki. (2017) Successful synthesis of active human coagulation factor VII by co-expression of mammalian gamma-glutamyl carboxylase and modification of vit.K cycle in Drosophila Schneider S2 cells. Cytotechnology 69:2, pages 317-327.
Crossref
Crossref
Zygmunt Warzecha, Paweł Sendur, Piotr Ceranowicz, Marcin Dembiński, Jakub Cieszkowski, Beata Kuśnierz-Cabala, Rafał Olszanecki, Romana Tomaszewska, Tadeusz Ambroży & Artur Dembiński. (2016) Protective Effect of Pretreatment with Acenocoumarol in Cerulein-Induced Acute Pancreatitis. International Journal of Molecular Sciences 17:10, pages 1709.
Crossref
Crossref
Paweł Mateusz Nowak, Michał Woźniakiewicz, Monika Piwowarska & Paweł Kościelniak. (2016) Determination of acid dissociation constant of 20 coumarin derivatives by capillary electrophoresis using the amine capillary and two different methodologies. Journal of Chromatography A 1446, pages 149-157.
Crossref
Crossref
Sun Eun LeeKerry J. SchulzeRobert N. ColeLee S. F. WuJames D. YagerJohn GroopmanParul ChristianKeith P. WestJr.Jr.. (2016) Biological Systems of Vitamin K: A Plasma Nutriproteomics Study of Subclinical Vitamin K Deficiency in 500 Nepalese Children. OMICS: A Journal of Integrative Biology 20:4, pages 214-223.
Crossref
Crossref
Mohd Z.H. Haniza, Sally Adams, Eleanor P. Jones, Alan MacNicoll, Eamonn B. Mallon, Robert H. Smith & Mark S. Lambert. (2015)
Large-scale structure of brown rat (
Rattus norvegicus
) populations in England: effects on rodenticide resistance
. PeerJ 3, pages e1458.
Crossref
Crossref
Sol Schulman & Bruce Furie. (2015) How I treat poisoning with vitamin K antagonists. Blood 125:3, pages 438-442.
Crossref
Crossref
Maren Podszun & Jan Frank. (2014) Vitamin E–drug interactions: molecular basis and clinical relevance. Nutrition Research Reviews 27:2, pages 215-231.
Crossref
Crossref
Christine H. Parker, Christopher R. Morgan, Kasper D. Rand, John R. Engen, James W. Jorgenson & Darrel W. Stafford. (2014) A Conformational Investigation of Propeptide Binding to the Integral Membrane Protein γ-Glutamyl Carboxylase Using Nanodisc Hydrogen Exchange Mass Spectrometry. Biochemistry 53:9, pages 1511-1520.
Crossref
Crossref
Jürgen Römisch & Katharina Pock. 2013. Production of Plasma Proteins for Therapeutic Use. Production of Plasma Proteins for Therapeutic Use
65
79
.
Benjamin J. Josey, Elizabeth S. Inks, Xuejun Wen & C. James Chou. (2013) Structure–Activity Relationship Study of Vitamin K Derivatives Yields Highly Potent Neuroprotective Agents. Journal of Medicinal Chemistry 56:3, pages 1007-1022.
Crossref
Crossref
Roger Lundblad. 2012. Biotechnology of Plasma Proteins. Biotechnology of Plasma Proteins
367
400
.
Martijn L.L. Chatrou, Kristien Winckers, Tilman M. Hackeng, Chris P. Reutelingsperger & Leon J. Schurgers. (2012) Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists. Blood Reviews 26:4, pages 155-166.
Crossref
Crossref
P. Medina, E. Bonet, S. Navarro, L. Martos, A. Estellés, F. Ferrando, V. Vicente, R. M. Bertina & F. España. (2012) Effects of oral anticoagulant therapy and haplotype 1 of the endothelial protein C receptor gene on activated protein C levels. Thrombosis and Haemostasis 107:3, pages 448-457.
Crossref
Crossref
E F HildebrandtJ W Suttie. (1983) The effects of salicylate on enzymes of vitamin K metabolism. Journal of Pharmacy and Pharmacology 35:7, pages 421-426.
Crossref
Crossref
Thomas Z?gg & Hans Brandstetter. 2011. Proteases in Health and Disease. Proteases in Health and Disease
51
103
.
Kensuke P. Watanabe, Aksorn Saengtienchai, Kazuyuki D. Tanaka, Yoshinori Ikenaka & Mayumi Ishizuka. (2010) Comparison of warfarin sensitivity between rat and bird species. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 152:1, pages 114-119.
Crossref
Crossref
Shayna L Showalter, Ziqiu Wang, Christina L Costantino, Agnieszka K Witkiewicz, Charles J Yeo, Jonathan R Brody & Brian I Carr. (2010) Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway. Journal of Gastroenterology and Hepatology 25:4, pages 738-744.
Crossref
Crossref
Kimie Nakagawa. (2010) New Developments in Research on Vitamin K Biosynthesis. JOURNAL OF HEALTH SCIENCE Journal of Health Science 56:6, pages 623-631.
Crossref
Crossref
REBECCA L C ADAMS & ROBERT J BIRD. (2009) Review article: Coagulation cascade and therapeutics update: Relevance to nephrology. Part 1: Overview of coagulation, thrombophilias and history of anticoagulants. Nephrology 14:5, pages 462-470.
Crossref
Crossref
Avi Cohen, Anat Shirvan, Galit Levin, Hagit Grimberg, Ayelet Reshef & Ilan Ziv. (2009) From the Gla domain to a novel small-molecule detector of apoptosis. Cell Research 19:5, pages 625-637.
Crossref
Crossref
Hagit Grimberg, Galit Levin, Anat Shirvan, Avi Cohen, Merav Yogev-Falach, Ayelet Reshef & Ilan Ziv. (2009) Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. Apoptosis 14:3, pages 257-267.
Crossref
Crossref
Thomas Zögg & Hans Brandstetter. (2009) Activation mechanisms of coagulation factor IX. Biological Chemistry 390:5/6.
Crossref
Crossref
Jeannine Yon-Kahn & G. HervéJeannine Yon-Kahn & Guy Hervé. 2010. Molecular and Cellular Enzymology. Molecular and Cellular Enzymology
251
266
.
Abdimajid Osman & Ulf Hannestad. (2008)
A possible ethanol-catalyzed rearrangement of vitamin K
1
detected by gas chromatography/mass spectrometry
. Rapid Communications in Mass Spectrometry 22:23, pages 3861-3866.
Crossref
Crossref
Xueyan Fu, Xiang-Dong Wang, Heather Mernitz, Reidar Wallin, M. Kyla Shea & Sarah L. Booth. (2008) 9-Cis Retinoic Acid Reduces 1 α,25-Dihydroxycholecalciferol-Induced Renal Calcification by Altering Vitamin K-Dependent γ-Carboxylation of Matrix γ-Carboxyglutamic Acid Protein in A/J Male Mice1,. The Journal of Nutrition 138:12, pages 2337-2341.
Crossref
Crossref
Toshio Okano, Yuka Shimomura, Makiko Yamane, Yoshitomo Suhara, Maya Kamao, Makiko Sugiura & Kimie Nakagawa. (2008) Conversion of Phylloquinone (Vitamin K1) into Menaquinone-4 (Vitamin K2) in Mice. Journal of Biological Chemistry 283:17, pages 11270-11279.
Crossref
Crossref
J. S. Johnson, B. A. Soute, C. S. Olver & D. C. Baker. (2016) Defective ?-Glutamyl Carboxylase Activity and Bleeding in Rambouillet Sheep. Veterinary Pathology 43:5, pages 726-732.
Crossref
Crossref
Atif ZaheerMonzur MurshedAlec M. De GrandTimothy G. MorganGerard KarsentyJohn V. Frangioni. (2006) Optical Imaging of Hydroxyapatite in the Calcified Vasculature of Transgenic Animals. Arteriosclerosis, Thrombosis, and Vascular Biology 26:5, pages 1132-1136.
Crossref
Crossref
Pen-Jen Lin, David L. Straight & Darrel W. Stafford. (2004) Binding of the Factor IX γ-Carboxyglutamic Acid Domain to the Vitamin K-dependent γ-Glutamyl Carboxylase Active Site Induces an Allosteric Effect That May Ensure Processive Carboxylation and Regulate the Release of Carboxylated Product. Journal of Biological Chemistry 279:8, pages 6560-6566.
Crossref
Crossref
Vasantha P. Mutucumarana, Francine Acher, David L. Straight, Da-Yun Jin & Darrel W. Stafford. (2003) A Conserved Region of Human Vitamin K-dependent Carboxylase between Residues 393 and 404 Is Important for Its Interaction with the Glutamate Substrate. Journal of Biological Chemistry 278:47, pages 46488-46493.
Crossref
Crossref
E.L. Saenko, N.M. Ananyeva, M. Shima, C.A.E. Hauser & S.W. Pipe. (2003) The future of recombinant coagulation factors. Journal of Thrombosis and Haemostasis 1:5, pages 922-930.
Crossref
Crossref
Marleen J. A. SimmelinkPhilip G. de GrootRonald H. W. M. DerksenJosé A. FernándezJohn H. Griffin. (2002) Oral anticoagulation reduces activated protein C less than protein C and other vitamin K–dependent clotting factors. Blood 100:12, pages 4232-4233.
Crossref
Crossref
Jiro Takata, Kazuhisa Matsunaga & Yoshiharu Karube. (2002) Delivery systems for antioxidant nutrients. Toxicology 180:2, pages 183-193.
Crossref
Crossref
A. Fregin. (2002) Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16. Blood 100:9, pages 3229-3232.
Crossref
Crossref
Vasantha P. Mutucumarana, Darrel W. Stafford, Thomas B. Stanley, Da-Yun Jin, Jesus Solera, Benjamin Brenner, Robert Azerad & Sheue-Mei Wu. (2000) Expression and Characterization of the Naturally Occurring Mutation L394R in Human γ-Glutamyl Carboxylase. Journal of Biological Chemistry 275:42, pages 32572-32577.
Crossref
Crossref
Susumu Itoh & Shoju Onishi. (2000) Developmental changes of vitamin K epoxidase and reductase activities involved in the vitamin K cycle in human liver. Early Human Development 57:1, pages 15-23.
Crossref
Crossref
Valery Larue, Josyane Gharbi-Benarous, Francine Acher, Veerappan Arulmozhi, Carine Tisné, Nathalie Todeschi, Robert Azerad & Jean-Pierre Girault. (1997) Solution conformation of α, β or γ-methylglutamyl-containing derivatives as probes of vitamin K-dependent carboxylase using molecular modelling and nuclear magnetic resonance. International Journal of Biological Macromolecules 20:2, pages 131-159.
Crossref
Crossref
David W. DeerfieldIIII & Lee G. Pedersen. (1996) Enol and deprotonated forms of acetic and malonic acid. Journal of Molecular Structure: THEOCHEM 368, pages 163-171.
Crossref
Crossref
Daniel P. Morris, Robert D. Stevens, David J. Wright & Darrel W. Stafford. (1995) Processive Post-translational Modification. Journal of Biological Chemistry 270:51, pages 30491-30498.
Crossref
Crossref
Wen-Lin Kuo, Darrel W. Stafford, Jesús Cruces, Joe Gray & Solera Jesú. (1995) Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12. Genomics 25:3, pages 746-748.
Crossref
Crossref
D.P. Morris, B.A. Soute, C. Vermeer & D.W. Stafford. (1993) Characterization of the purified vitamin K-dependent gamma-glutamyl carboxylase.. Journal of Biological Chemistry 268:12, pages 8735-8742.
Crossref
Crossref
F. von Bruchhausen, S. Ebel, E. Hackenthal, G. Dannhardt, A. W. Frahm, U. Holzgrabe, K. Keller, E. Nürnberg, H. Rimpler, G. Schneider, P. Surmann, H. U. Wolf & G. Wurm. 1993. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis
787
1056
.
R. Coppola, S. Tombesi, F. Valentini, S. Alborali, A. Albertini & P.M. Mannucci. (1992) Characterization of a CA (II)-independent monoclonal antibody that lacks reactivity with gla-domainless human factor VII. Thrombosis Research 68:3, pages 269-281.
Crossref
Crossref
Ramesh Soundararajan, David J. Leehey, Alex W. Yu, Todd S. Ing & J.Bruce Miller. (1992) Skin necrosis and protein C deficiency associated with vitamin K depletion in a patient with renal failure. The American Journal of Medicine 93:4, pages 467-470.
Crossref
Crossref
D.J. Weber, P Berkowitz, M.G. Panek, N.W. Huh, L.G. Pedersen & R.G. Hiskey. (1992) Modifications of bovine prothrombin fragment 1 in the presence and absence of Ca(II) ions. Loss of positive cooperativity in Ca(II) ion binding for the modified proteins.. Journal of Biological Chemistry 267:7, pages 4564-4569.
Crossref
Crossref
Enrique Cadenas, Paul Hochstein & Lars Ernster. 1992. Advances in Enzymology and Related Areas of Molecular Biology. Advances in Enzymology and Related Areas of Molecular Biology
97
146
.
Berry A.M. Soute, Ron Budé & Cees Vermeer. (1991) Vitamin K-dependent car☐ylation of poly-l-glutamate. Biochimica et Biophysica Acta (BBA) - General Subjects 1073:2, pages 434-436.
Crossref
Crossref
P. R. Winship & A. C. Dragon. (2008) Identification of haemophilia B patients with mutations in the two calcium binding domains of factor IX: importance of a β‐OH Asp 64→Asn change. British Journal of Haematology 77:1, pages 102-109.
Crossref
Crossref
G. E. Veenstra, D. E. Owen & K. R. Huckle. 1991. Recent Developments in Toxicology: Trends, Methods and Problems. Recent Developments in Toxicology: Trends, Methods and Problems
160
165
.
Christina Lind, Enrique Cadenas, Paul Hochstein & Lars Ernster. 1990. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants
287
301
.
Enrique Cadenas & Lars Ernster. 1990. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants
180
196
.
B R Hubbard, M Jacobs, M M Ulrich, C Walsh, B Furie & B C Furie. (1989) Vitamin K-dependent carboxylation. Journal of Biological Chemistry 264:24, pages 14145-14150.
Crossref
Crossref
Takashi Matsubara, Akira Touchi, Toshio Harauchi, Kyoji Takano & Toshio Yoshizaki. (1989) Depression of liver microsomal vitamin K epoxide reductase activity associated with antibiotic-induced coagulopathy. Biochemical Pharmacology 38:16, pages 2693-2701.
Crossref
Crossref
Maria Carla Roncaglioni, Ine Reyers, Chiara Cerletti, Maria Benedetta Donati & Giovanni de Gaetano. (1988) Moderate anticoagulation by salicylate prevents thrombosis without bleeding complications. Biochemical Pharmacology 37:24, pages 4743-4745.
Crossref
Crossref
Richard B. Silverman & Dhirendra L. Nandi. (1988) Reduced thioredoxin: A possible physiological cofactor for vitamin k epoxide reductase. further support for an active site disulfide. Biochemical and Biophysical Research Communications 155:3, pages 1248-1254.
Crossref
Crossref
K. Burger, P. Sipos, M. Véber, I. Horváth, B. Noszál & M. Löw. (1988) Formation microequilibria of proton, calcium and magnesium complexes of the γ-carboxyglutamate ion and related compounds. Inorganica Chimica Acta 152:4, pages 233-239.
Crossref
Crossref
David J. Weber, Jennifer S. Pollock, Lee G. Pedersen & Richard G. Hiskey. (1988) The determination of a calcium-dependent binding constant of the bovine prothrombin GLA domain (residues 1–45) to phospholipid vesicles. Biochemical and Biophysical Research Communications 155:1, pages 230-235.
Crossref
Crossref
Ulku S. Ramelow. (1988) The mechanism of enzymically induced chemiluminescence reactions of lucigenin. Journal of Photochemistry and Photobiology B: Biology 2:1, pages 91-108.
Crossref
Crossref
Lasse Uotila. (1988) Vitamin K-dependent carboxylase from calf liver: Studies on the steady-state kinetic mechanism. Archives of Biochemistry and Biophysics 264:1, pages 135-143.
Crossref
Crossref
Leena S. Trivedi, Myung Rhee, John H. Galivan & Michael J. Fasco. (1988) Normal and warfarin-resistant rat hepatocyte metabolism of vitamin K 2,3-epoxide: Evidence for multiple pathways of hydroxyvitamin K formation. Archives of Biochemistry and Biophysics 264:1, pages 67-73.
Crossref
Crossref
B. Connor Johnson. (1988) The vitamin K dependent reaction. Journal of Chromatography A 440, pages 499-508.
Crossref
Crossref
Bruce Furie & Barbara C. Furie. (1988) The molecular basis of blood coagulation. Cell 53:4, pages 505-518.
Crossref
Crossref
Alain BALLAND, Thérèse FAURE, Dorothée CARVALLO, Pascale CORDIER, Pascale ULRICH, Bernard FOURNET, Henri DE LA SALLE & Jean‐Pierre LECOCQ. (2005) Characterisation of two differently processed forms of human recombinant factor IX synthesised in CHO cells transformed with a polycistronic vector. European Journal of Biochemistry 172:3, pages 565-572.
Crossref
Crossref
Tatsushi OKA, Akira TOUCHI, Kiyoshi EZUMI, Masumi YAMAKAWA & Takashi MATSUBARA. (1988) In Vitro Effects of Various Heterocyclic Thiol Compounds and β-Lactam Antibiotics on Vitamin K-Dependent γ-Glutamylcarboxylation Activity in Liver Microsomes. Japanese Journal of Pharmacology 46:2, pages 165-172.
Crossref
Crossref
Minoru MATSUURA, Seiji SATOH, Kyoji TAKANO, Toshio HARAUCHI, Toshio YOSHIZAKI, Fumihiko KOBAYASHI, Takashi MATSUBARA & Kiyohisa UCHIDA. (1988) Vitamin K-Reversible Hypoprothrombinemia in Rats I. Sex Differences in the Development of Hypoprothrombinemia and the Effects of Beta-Lactam Antibiotics. Japanese Journal of Pharmacology 46:3, pages 303-310.
Crossref
Crossref
Keiko KAWAMOTO, Akira TOUCHI, Koichi SUGENO & Takashi MATSUBARA. (1988) In Vitro Effect of Beta-Lactam Antibiotics and N-Methyl-Tetrazolethiol on Microsomal Vitamin K Epoxide Reductase in Rats. Japanese Journal of Pharmacology 47:2, pages 169-178.
Crossref
Crossref
Minoru MATSUURA, Seiji SATOH, Fumihiko KOBAYASHI, Takashi MATSUBARA & Kiyohisa UCHIDA. (1988) Vitamin K Reversible Hypoprothrombinemia in Rats II. Efficacy of Vitamin K on Latamoxef-Induced Coagulopathy in Rats. Japanese Journal of Pharmacology 47:4, pages 357-365.
Crossref
Crossref
Johan Meijer & Joseph W. Depierre. (1988) Cytosolic epoxide hydrolase. Chemico-Biological Interactions 64:3, pages 207-249.
Crossref
Crossref
E Chan, L Aarons, M Serlin, A Breckenridge & M Rowland. (2012) Inter‐relationship among individual vitamin K‐dependent clotting factors at different levels of anticoagulation.. British Journal of Clinical Pharmacology 24:5, pages 621-625.
Crossref
Crossref
M J Rabiet, M J Jorgensen, B Furie & B C Furie. (1987) Effect of propeptide mutations on post-translational processing of factor IX. Evidence that beta-hydroxylation and gamma-carboxylation are independent events.. Journal of Biological Chemistry 262:31, pages 14895-14898.
Crossref
Crossref
Michael J. Fasco, Adrian C. Wilson, David Lincoln & John Gierthy. (2006) Evidence for a warfarin‐sensitive serum factor that participates in factor x activation by lewis lung tumor cells. International Journal of Cancer 39:5, pages 631-637.
Crossref
Crossref
Trevor M. Kitson. (1987) The effect of cephalosporin antibiotics on alcohol metabolism: A review. Alcohol 4:3, pages 143-148.
Crossref
Crossref
Paul A. Price & Yuri Kaneda. (1987) Vitamin K counteracts the effect of warfarin in liver but not in bone. Thrombosis Research 46:1, pages 121-131.
Crossref
Crossref
D.W. Deerfield2nd2nd, D.L. Olson, P. Berkowitz, P.A. Byrd, K.A. Koehler, L.G. Pedersen & R.G. Hiskey. (1987) Mg(II) binding by bovine prothrombin fragment 1 via equilibrium dialysis and the relative roles of Mg(II) and Ca(II) in blood coagulation.. Journal of Biological Chemistry 262:9, pages 4017-4023.
Crossref
Crossref
Michael J. Fasco, Adrian C. Wilson, Robert G. Briggs & John F. Gierthy. (1987) Identification of vitamin K1 chromenol—A novel metabolite of vitamin K1 formed in vitro by a component in blood. Archives of Biochemistry and Biophysics 252:2, pages 501-506.
Crossref
Crossref
Tatsushi OKA, Akira TOUCHI & Takashi MATSUBARA. (1987) Effect of N-Methyltetrazolethiol on Liver Microsomal gamma-Glutamylcarboxylation: Modification of the In Vitro Action of N-Methyltetrazolethiol. Japanese Journal of Pharmacology 44:4, pages 461-470.
Crossref
Crossref
Judith S. Bond & Robert J. Beynon. (1987) Proteolysis and physiological regulation. Molecular Aspects of Medicine 9:3, pages 173-287.
Crossref
Crossref
Adrian C. Wilson & Michael J. Fasco. (2006) Vitamin‐K‐dependent proteins in microsomes of primary lewis lung tumors. International Journal of Cancer 38:6, pages 877-882.
Crossref
Crossref
Lucia Pezzi, Marco Gerna, Maria Carla Roncaglioni, Cees Vermeer & Maria Benedetta Donati. (1986) Increased susceptibility to the anticoagulant effect of warfarin in mice bearing the lewis lung carcinoma. Biochemical Pharmacology 35:19, pages 3239-3242.
Crossref
Crossref
M.C. Roncaglioni, M.M.W. Ulrich, A.D. Muller, B.A.M. Soute, M.A.G. de Boer-van den Berg & C. Vermeer. (1986) The vitamin k-antagonism of salicylate and warfarin. Thrombosis Research 42:6, pages 727-736.
Crossref
Crossref
Toshio HARAUCHI, Kyoji TAKANO, Minoru MATSUURA & Toshio YOSHIZAKI. (1986) Liver and Plasma Levels of Descarboxyprothrombin (PIVKA II) in Vitamin K Deficiency in Rats. Japanese Journal of Pharmacology 40:4, pages 491-499.
Crossref
Crossref
C. Vermeer. 1986. Blood Coagulation. Blood Coagulation
87
101
.
Reidar Wallin. (1986) Rat liver vitamin K-dependent carboxylase: A study of antibodies raised against partially purified preparations of the enzyme. International Journal of Biochemistry 18:2, pages 123-130.
Crossref
Crossref
Jung Ja Lee, Louise M. Principe & Michael J. Fasco. (2002) Identification of a Warfarin-sensitive protein component in a 200S rat liver microsomal fraction catalyzing vitamin K and vitamin K 2,3-epoxide reduction. Biochemistry 24:25, pages 7063-7070.
Crossref
Crossref
Peter I. Karl, David L. Carnes & Paul A. Friedman. (1985) Effects of 1,25-dihydroxycholecalciferol administration on the rat renal vitamin K-dependent carboxylating system. FEBS Letters 192:2, pages 243-246.
Crossref
Crossref
M S Johnson & S A Kuby. (1985) Studies on NADH (NADPH)-cytochrome c reductase (FMN-containing) from yeast. Isolation and physicochemical properties of the enzyme from top-fermenting ale yeast.. Journal of Biological Chemistry 260:22, pages 12341-12350.
Crossref
Crossref
L E Sommerville, D D Thomas & G L Nelsestuen. (1985) Tb3+ binding to bovine prothrombin and bovine prothrombin fragment 1.. Journal of Biological Chemistry 260:19, pages 10444-10452.
Crossref
Crossref
Marian A.G. de Boer-van den Berg, Magda M.W. Ulrich, H.Coenraad Hemker, Berry A.M. Soute & Cees Vermeer. (1985) Vitamin K-dependent carboxylase: the carboxylation of exogenous substrates in different systems. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 831:1, pages 94-98.
Crossref
Crossref
Sharon Busby, Ashok Kumar, Michael Joseph, Laurel Halfpap, Maggie Insley, Kathleen Berkner, Kotoku Kurachi & Richard Woodbury. (1985) Expression of active human factor IX in transfected cells. Nature 316:6025, pages 271-273.
Crossref
Crossref
J. C. Swanson & J. W. Suttie. (2002) Prothrombin biosynthesis: characterization of processing events in rat liver microsomes. Biochemistry 24:15, pages 3890-3897.
Crossref
Crossref
Vera J. Stecher, John A. Carlson, Kevin M. Connolly & Denis M. Bailey. (2006) Disease‐modifying antirheumatic drugs. Medicinal Research Reviews 5:3, pages 371-390.
Crossref
Crossref
D. S. Anson, D. E. G. Austen & G. G. Brownlee. (1985) Expression of active human clotting factor IX from recombinant DNA clones in mammalian cells. Nature 315:6021, pages 683-685.
Crossref
Crossref
Alan D. MacNicoll. (1985) A comparison of warfarin resistance and liver microsomal vitamin K epoxide reductase activity in rats. Biochimica et Biophysica Acta (BBA) - General Subjects 840:1, pages 13-20.
Crossref
Crossref
Louise M. Canfield, Laura A. Davy & Gregory L. Thomas. (1985) Anti-oxidant/pro-oxidant reactions of vitamin K. Biochemical and Biophysical Research Communications 128:1, pages 211-219.
Crossref
Crossref
Rowan T. Chlebowski, Steven A. Akman & Jerome B. Block. (1985) Vitamin K in the treatment of cancer. Cancer Treatment Reviews 12:1, pages 49-63.
Crossref
Crossref
Jane B. Lian, Caren M. Gundberg, Peter V. Hauschka & Paul M. Gallop. 1985. Glutamate, Glutamine, Glutathione, and Related Compounds. Glutamate, Glutamine, Glutathione, and Related Compounds
133
146
.
Peter I. Karl & Paul A. Friedman. (1985) Responses of renal and hepatic vitamin k dependent γ-glutamyl carboxylase substrates to warfarin and vitamin k treatments. International Journal of Biochemistry 17:12, pages 1313-1316.
Crossref
Crossref
P Decottignies-Le Maréchal, C Ducrocq, A Marquet & R Azerad. (1984) The stereochemistry of hydrogen abstraction in vitamin K-dependent carboxylation.. Journal of Biological Chemistry 259:24, pages 15010-15012.
Crossref
Crossref
Eryka Guibé, Paulette Decottignies-Le Maréchal, Pierre Le Maréchal & Robert Azerad. (1984) Vitamin K-dependent carboxylation: inhibition by a peptide containing 4-methylene glutamic acid. FEBS Letters 177:2, pages 265-268.
Crossref
Crossref
SONIA BORY, JOËLLE DUBOIS, MICHEL GAUDRY & ANDRÉE MARQUET. (2009) Vitamin‐K‐dependent carboxylation. International Journal of Peptide and Protein Research 24:5, pages 505-515.
Crossref
Crossref
Peter C. Preusch & John W. Suttie. (1984) Lapachol inhibition of vitamin K epoxide reductase and vitamin K quinone reductase. Archives of Biochemistry and Biophysics 234:2, pages 405-412.
Crossref
Crossref
D.V. Shah, J.C. Swanson & J.W. Suttie. (1984) Abnormal prothrombin in the vitamin K-deficient rat. Thrombosis Research 35:4, pages 451-458.
Crossref
Crossref
Jung Ja Lee & Michael J. Fasco. (2002) Metabolism of vitamin K and vitamin K 2,3-epoxide via interaction with a common disulfide. Biochemistry 23:10, pages 2246-2252.
Crossref
Crossref
Peter C. Preusch & John W. Suttie. (1984) Formation of 3-Hydroxy-2,3-dihydrovitamin K1 In Vivo: Relationship to Vitamin K Epoxide Reductase and Warfarin Resistance. The Journal of Nutrition 114:5, pages 902-910.
Crossref
Crossref
Joel S. Bennett. (1984) Blood Coagulation and Coagulation Tests. Medical Clinics of North America 68:3, pages 557-576.
Crossref
Crossref
Louise M. Canfield & Ulkü Ramelow. (1984) Vitamin K-dependent carboxylase: Evidence for a semiquinone radical intermediate. Archives of Biochemistry and Biophysics 230:2, pages 389-399.
Crossref
Crossref
J J McTigue, M K Dhaon, D H Rich & J W Suttie. (1984) Vitamin K-dependent carboxylase. Carboxylation of aspartyl residues to beta-carboxyaspartyl residues in synthetic substrates.. Journal of Biological Chemistry 259:7, pages 4272-4278.
Crossref
Crossref
Alan D. MacNicoll, Allan K. Nadian & Michael G. Townsend. (1984) Inhibition by warfarin of liver microsomal vitamin K-reductase in warfarin-resistant and susceptible rats. Biochemical Pharmacology 33:8, pages 1331-1336.
Crossref
Crossref
E.F. Hildebrandt, P.C. Preusch, J.L. Patterson & J.W. Suttie. (1984) Solubilization and characterization of vitamin K epoxide reductase from normal and warfarin-resistant rat liver microsomes. Archives of Biochemistry and Biophysics 228:2, pages 480-492.
Crossref
Crossref
Berry A.M. Soute, Marian A.G. de Boer-v.d. Berg & Cees Vermeer. (1984) The separation of bovine prothrombin and descarboxyprothrombin by high-performance liquid chromatography. Analytical Biochemistry 137:1, pages 227-229.
Crossref
Crossref
Kiyohisa UCHIDA, Toyokazu ISHIGAMI & Taichiro KOMENO. (1984) Effects of Latamoxef and Methyltetrazolethiol on Gamma-Glutamylcarboxylase Activity. Japanese Journal of Pharmacology 35:3, pages 330-333.
Crossref
Crossref
Louise M. Canfield & Rita B. Holzman. (1984) Reaction of vitamin k and dithiothreitol on reversed-phase C18 high-performance liquid chromatographic columns. Journal of Chromatography A 299, pages 225-231.
Crossref
Crossref
Marian A. G. De Boer-V. D. Berg, M. Carla Roncaglioni, Berry A. M. Soute, Menno De Metz & Cees Vermeer. 1984. Haemostatic Failure in Liver Disease. Haemostatic Failure in Liver Disease
24
35
.
D L Anton & P A Friedman. (1983) Fate of the activated gamma-carbon-hydrogen bond in the uncoupled vitamin K-dependent gamma-glutamyl carboxylation reaction.. Journal of Biological Chemistry 258:23, pages 14084-14087.
Crossref
Crossref
Michael J. Fasco, Louise M. Principe, William A. Walsh & Paul A. Friedman. (2002) Warfarin inhibition of vitamin K 2,3-epoxide reductase in rat liver microsomes. Biochemistry 22:24, pages 5655-5660.
Crossref
Crossref
J J McTigue & J W Suttie. (1983) Vitamin K-dependent carboxylase. Demonstration of a vitamin K- and O2-dependent exchange of 3H from 3H2O into glutamic acid residues.. Journal of Biological Chemistry 258:20, pages 12129-12131.
Crossref
Crossref
. (2009) Conversion Of Vitamin K Epoxide To Hydroxyvitamin K By Liver Microsomes From Warfarin-Resistant Rats. Nutrition Reviews 41:8, pages 253-254.
Crossref
Crossref
Peter C. Preusch & John W. Suttie. (1983) Mechanism of ticrynafen potentiation of coumarin anticoagulant action. Biochemical Pharmacology 32:16, pages 2393-2398.
Crossref
Crossref
M.Carla Roncaglioni, Berry A.M. Soute, Marian A.G. de Boer - v.d. Berg & Cees Vermeer. (1983) Warfarin-induced accumulation of vitamin K-dependent proteins comparison between hepatic and non-hepatic tissues. Biochemical and Biophysical Research Communications 114:3, pages 991-997.
Crossref
Crossref
Takami Ueno & J.W. Suttie. (1983) High-pressure liquid chromatographic-reductive electrochemical detection analysis of serum trans-phylloquinone. Analytical Biochemistry 133:1, pages 62-67.
Crossref
Crossref
Charles M. Siegfried. (1983) Purification and properties of a factor from rat liver cytosol which stimulates vitamin K epoxide reductase. Archives of Biochemistry and Biophysics 223:1, pages 129-139.
Crossref
Crossref
M J Fasco, P C Preusch, E Hildebrandt & J W Suttie. (1983) Formation of hydroxyvitamin K by vitamin K epoxide reductase of warfarin-resistant rats.. Journal of Biological Chemistry 258:7, pages 4372-4380.
Crossref
Crossref
D.V. Shah, J.C. Swanson & J.W. Suttie. (1983) Vitamin K-dependent carboxylase: Effect of detergent concentrations, vitamin K status, and added protein precursors on activity. Archives of Biochemistry and Biophysics 222:1, pages 216-221.
Crossref
Crossref
Daniel H. Rich, Megumi Kawai, Hedda L. Goodman, Jean Engelke & J.W. Suttie. (1983) Vitamin K-dependent carboxylase: Synthesis of an inhibitor of the glutamyl binding site. FEBS Letters 152:1, pages 79-82.
Crossref
Crossref
Adrian C. Wilson & B.Kevin Park. (1983) Quantitative analysis of pharmacological levels of vitamin K1 and vitamin K1 2,3-epoxide in rabbit plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 277, pages 292-299.
Crossref
Crossref
P C Preusch & J W Suttie. (1983) Stereospecificity of vitamin K-epoxide reductase.. Journal of Biological Chemistry 258:2, pages 714-716.
Crossref
Crossref
Paul A. Friedman, David L. Anton & Stephen K. Kwan. 1983. Posttranslational Covalent Modifications of Proteins. Posttranslational Covalent Modifications of Proteins
281
294
.
J.W. Suttie, P.C. Preusch & J.J. McTigue. 1983. Posttranslational Covalent Modifications of Proteins. Posttranslational Covalent Modifications of Proteins
253
279
.
Philip CohenPhilip Cohen. 1983. Control of Enzyme Activity. Control of Enzyme Activity
25
41
.
J. C. Swanson & J. W. Suttie. (2002) Vitamin K dependent in vitro production of prothrombin. Biochemistry 21:23, pages 6011-6018.
Crossref
Crossref
M J Fasco, E F Hildebrandt & J W Suttie. (1982) Evidence that warfarin anticoagulant action involves two distinct reductase activities.. Journal of Biological Chemistry 257:19, pages 11210-11212.
Crossref
Crossref
Berry A.M. Soute, Menno de Metz & Cees Vermeer. (1982) Characteristics of vitamin K-dependent carboxylating systems from human liver and placenta. FEBS Letters 146:2, pages 365-368.
Crossref
Crossref
P A Friedman, W E Mitch & P Silva. (1982) Localization of renal vitamin K-dependent gamma-glutamyl carboxylase to tubule cells.. Journal of Biological Chemistry 257:18, pages 11037-11040.
Crossref
Crossref
P.J. Bunyan & P.I. Stanley. (1982) Toxic mechanisms in wildlife. Regulatory Toxicology and Pharmacology 2:2, pages 106-145.
Crossref
Crossref
E. F. Hildebrandt & J. W. Suttie. (2002) Mechanism of coumarin action: sensitivity of vitamin K metabolizing enzymes of normal and warfarin-resistant rat liver. Biochemistry 21:10, pages 2406-2411.
Crossref
Crossref
W K Sietsema & H F DeLuca. (1982) Retinoic acid 5,6-epoxidase. Properties and biological significance.. Journal of Biological Chemistry 257:8, pages 4265-4270.
Crossref
Crossref
Reidar Wallin & John W. Suttie. (1982) Vitamin K-dependent carboxylase: Evidence for cofractionation of carboxylase and epoxidase activities, and for carboxylation of a high-molecular-weight microsomal protein. Archives of Biochemistry and Biophysics 214:1, pages 155-163.
Crossref
Crossref
R. Wallin & S. Hutson. (1982) Vitamin K-dependent carboxylation. Evidence that at least two microsomal dehydrogenases reduce vitamin K1 to support carboxylation.. Journal of Biological Chemistry 257:4, pages 1583-1586.
Crossref
Crossref
C. Vermeer, B.A.M. Soute, M. De Metz & H.C. Hemker. (1982) A comparison between vitamin K-dependent carboxylase from normal and warfarin-treated cows. Biochimica et Biophysica Acta (BBA) - General Subjects 714:2, pages 361-365.
Crossref
Crossref
M. De Metz, B.A.M. Soute, H.C. Hemker & C. Vermeer. (1982) The inhibition of vitamin K-dependent carboxylase by cyanide. FEBS Letters 137:2, pages 253-256.
Crossref
Crossref
Linda J. Van Eldik, Joseph G. Zendegui, Daniel R. Marshak & D. Martin Watterson. 1982. International Review of Cytology Volume 77. International Review of Cytology Volume 77
1
61
.
BARBARA C. FURIE, MARIANNE BOROWSKI, BRUCE KEYT & BRUCE FURIE. 1982. Calcium and Cell Function. Calcium and Cell Function
217
242
.
Bruce Furie, Rita A. Blanchard, David J. Robison, Mindy M. Tai & Barbara C. Furie. 1982. Immunochemical Techniques Part D: Selected Immunoassays. Immunochemical Techniques Part D: Selected Immunoassays
60
83
.
Peter C. Preusch & John W. Suttie. (1981) Vitamin K-Dependent Reactions in Rat Liver: Role of Flavoproteins. The Journal of Nutrition 111:12, pages 2087-2097.
Crossref
Crossref
A.E. Larson, P.A. Friedman & J.W. Suttie. (1981) Vitamin K-dependent carboxylase. Stoichiometry of carboxylation and vitamin K 2,3-epoxide formation.. Journal of Biological Chemistry 256:21, pages 11032-11035.
Crossref
Crossref
M. de Metz, C. Vermeer, B.A. Soute & H.C. Hemker. (1981) Identification of phospholipid as an essential part of bovine vitamin K-dependent carboxylase.. Journal of Biological Chemistry 256:21, pages 10843-10846.
Crossref
Crossref
John P. Burnier, Marianne Borowski, Barbara C. Furie & Bruce Furie. (1981) Gamma-carboxyglutamic acid. Molecular and Cellular Biochemistry 39:1, pages 191-207.
Crossref
Crossref
DANIEL H. RICH, MEGUMI KAWAI, HEDDA L. GOODMAN & JOHN W. SUTTIE. (2009) SYNTHESIS OF TWO ANALOGS OF A CYCLIC HEXAPEPTIDE WITH DISULFIDE BRIDGE CORRESPONDING TO BOVINE PROTHROMBIN PRECURSOR SEQUENCE 18-23: Extent of Carboxylation by Vitamin K-Dependent Carboxylase. International Journal of Peptide and Protein Research 18:1, pages 41-51.
Crossref
Crossref
Sheri Almeda, David H. Bing, Richard Laura & Paul A. Friedman. (2002) Photoaffinity inhibition of rat liver NAD(P)H dehydrogenase by 3-(.alpha.-acetonyl-p-azidobenzyl)-4-hydroxycoumarin. Biochemistry 20:13, pages 3731-3737.
Crossref
Crossref
J. W. Suttie, J. McTigue, A. E. Larson & R. Wallin. (1981) BIOSYNTHESIS OF PROTHROMBIN COMPLEX PROTEINS*. Annals of the New York Academy of Sciences 370:1, pages 271-280.
Crossref
Crossref
B. Connor Johnson. (1981) Post-translational carboxylation of preprothrombin. Molecular and Cellular Biochemistry 38:1, pages 77-121.
Crossref
Crossref
B. Connor Johnson. 1982. The Biological Effects of Glutamic Acid and Its Derivatives. The Biological Effects of Glutamic Acid and Its Derivatives
77
121
.
John P. Burnier, Marianne Borowski, Barbara C. Furie & Bruce Furie. 1982. The Biological Effects of Glutamic Acid and Its Derivatives. The Biological Effects of Glutamic Acid and Its Derivatives
191
207
.
J.W. Suttie. (1980) Vitamin K-dependent carboxylation. Trends in Biochemical Sciences 5:11, pages 302-304.
Crossref
Crossref