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Leukemia & Lymphoma Volume 41, 2001 - Issue 5-6
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Original Article

Apoptosis Inducing Novel Anti-Leukemic Agent, Bis(4,7-Dimethyl-1,10 Phenanthroline) Sulfatooxovanadium(IV)[VO(SO4)(Me2-Phen)2] Depolarizes Mitochondrial Membranes

Rama Krishna Narla Parker Hughes Cancer Center, Departments of Experimental Oncology and Chemistry, Drug Discovery Program Parker Hughes Institute, St Paul, Minnesota, 55113, USA
,
Yanhong Dong Parker Hughes Cancer Center, Departments of Experimental Oncology and Chemistry, Drug Discovery Program Parker Hughes Institute, St Paul, Minnesota, 55113, USA
&
Fatih M. Uckun Parker Hughes Cancer Center, Departments of Experimental Oncology and Chemistry, Drug Discovery Program Parker Hughes Institute, St Paul, Minnesota, 55113, USA
Pages 625-634 | Received 09 Sep 2000, Published online: 01 Jul 2009

Citations (11)

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Read on this site (1)

Osmond J D’Cruz & Fatih M Uckun. (2002) Metvan: a novel oxovanadium(IV) complex with broad spectrum anticancer activity. Expert Opinion on Investigational Drugs 11:12, pages 1829-1836.
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Articles from other publishers (10)

Marino F. A. Santos, Giuseppe Sciortino, Isabel Correia, Andreia C. P. Fernandes, Teresa Santos‐Silva, Federico Pisanu, Eugenio Garribba & João Costa Pessoa. (2022) Binding of V IV O 2+ , V IV OL, V IV OL 2 and V V O 2 L Moieties to Proteins: X‐ray/Theoretical Characterization and Biological Implications . Chemistry – A European Journal 28:40.
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Patrique Nunes, Isabel Correia, Isabel Cavaco, Fernanda Marques, Teresa Pinheiro, Fernando Avecilla & João Costa Pessoa. (2021) Therapeutic potential of vanadium complexes with 1,10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells. Journal of Inorganic Biochemistry 217, pages 111350.
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João Costa Pessoa & Isabel Correia. (2021) Misinterpretations in Evaluating Interactions of Vanadium Complexes with Proteins and Other Biological Targets. Inorganics 9:2, pages 17.
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Maria Le, Oliver Rathje, Aviva Levina & Peter A. Lay. (2017) High cytotoxicity of vanadium(IV) complexes with 1,10-phenanthroline and related ligands is due to decomposition in cell culture medium. JBIC Journal of Biological Inorganic Chemistry 22:5, pages 663-672.
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Tomoko Yamaguchi, Shinya Watanabe, Yuriko Matsumura, Yoshikazu Tokuoka & Akihiro Yokoyama. (2012) Oxovanadium complexes with quinoline and pyridinone ligands: Syntheses of the complexes and effect of alkyl chains on their apoptosis-inducing activity in leukemia cells. Bioorganic & Medicinal Chemistry 20:9, pages 3058-3064.
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Tomoko Yamaguchi, Shinya Watanabe, Yuriko Matsumura, Yoshikazu Tokuoka & Akihiro Yokoyama. (2012) Synthesis of Oxovanadium Complexes and Their Apoptosis-Inducing Activity in Leukemia Cells. Chemical and Pharmaceutical Bulletin 60:4, pages 508-512.
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Josefina Rivadeneira, Daniel A. Barrio, Gabriel Arrambide, Dinorah Gambino, Liliana Bruzzone & Susana B. Etcheverry. (2009) Biological effects of a complex of vanadium(V) with salicylaldehyde semicarbazone in osteoblasts in culture: Mechanism of action. Journal of Inorganic Biochemistry 103:4, pages 633-642.
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C Ma, J Zhang, L K Durrin, J Lv, D Zhu, X Han & Y Sun. (2006) The BCL2 major breakpoint region (mbr) regulates gene expression. Oncogene 26:18, pages 2649-2657.
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Fatih M. Uckun, Sanda Morar & Sanjive Qazi. (2006) Vinorelbine-based salvage chemotherapy for therapy-refractory aggressive leukaemias. British Journal of Haematology 135:4, pages 500-508.
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Zhen-yi Wang. (2003) Ham-Wasserman Lecture. Hematology 2003:1, pages 1-13.
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