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Review Article

Familial Hemophagocytic Lymphohistiocytosis: Too Little Cell Death Can Seriously Damage Your Health

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Pages 13-20 | Published online: 01 Jul 2009

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Read on this site (3)

Omer Jamy, Sara Nunnery, Smith Giri, Eric Wiedower, Benny Johnson, George Yaghmour & Mike G. Martin. (2016) Under-recognition of hemophagocytic syndrome in United States’ rural, non-teaching hospitals. Leukemia & Lymphoma 57:12, pages 2911-2913.
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Damali N. Martin, Isis S. Mikhail & Ola Landgren. (2009) Autoimmunity and hematologic malignancies: associations and mechanisms. Leukemia & Lymphoma 50:4, pages 541-550.
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Joseph Phillips, Harry Staszewski & Michael Garrison. (2008) Successful treatment of secondary hemophagocytic lymphohistiocytosis in a patient with disseminated histoplasmosis. Hematology 13:5, pages 282-285.
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Articles from other publishers (19)

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Kai Lehmberg, Fumihiro Ochi, Kim E. Nichols & Eiichi Ishii. 2018. Histiocytic Disorders. Histiocytic Disorders 215 231 .
Arthur ZimmermannArthur Zimmermann. 2017. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1807 1833 .
Arthur ZimmermannArthur Zimmermann. 2016. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1 28 .
Ling Zhang, Jun Zhou & Lubomir Sokol. (2014) Hereditary and Acquired Hemophagocytic Lymphohistiocytosis. Cancer Control 21:4, pages 301-312.
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Ryan McCormack, Lesley de Armas, Motoaki Shiratsuchi & Eckhard R. Podack. (2013) Killing machines: three pore-forming proteins of the immune system. Immunologic Research 57:1-3, pages 268-278.
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Jennifer E. LykensCatherine E. TerrellErin E. ZollerKimberly Risma & Michael B. Jordan. (2011) Perforin is a critical physiologic regulator of T-cell activation. Blood 118:3, pages 618-626.
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Eckhard R. Podack. 2010. Topley & Wilson's Microbiology and Microbial Infections. Topley & Wilson's Microbiology and Microbial Infections.
Nadine Rouphael Maakaroun, Abeer Moanna, Jesse T Jacob & Helmut Albrecht. (2010) Viral infections associated with haemophagocytic syndrome. Reviews in Medical Virology 20:2, pages 93-105.
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Elisabetta Orilieri, Giuseppe Cappellano, Rita Clementi, Angela Cometa, Massimo Ferretti, Elisa Cerutti, Francesco Cadario, Miryam Martinetti, Daniela Larizza, Valeria Calcaterra, Giuseppe D’Annunzio, Renata Lorini, Franco Cerutti, Graziella Bruno, Annalisa Chiocchetti & Umberto Dianzani. (2008) Variations of the Perforin Gene in Patients With Type 1 Diabetes. Diabetes 57:4, pages 1078-1083.
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Faramarz Naeim. 2008. Hematopathology. Hematopathology 489 512 .
Jan‐Inge Henter, AnnaCarin Horne, Maurizio Aricó, R. Maarten Egeler, Alexandra H. Filipovich, Shinsaku Imashuku, Stephan Ladisch, Ken McClain, David Webb, Jacek Winiarski & Gritta Janka. (2006) HLH‐2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatric Blood & Cancer 48:2, pages 124-131.
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P. F. Moore, V. K. Affolter & W. Vernau. (2016) Canine Hemophagocytic Histiocytic Sarcoma: A Proliferative Disorder of CD11d+ Macrophages. Veterinary Pathology 43:5, pages 632-645.
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Jan-Inge Henter, Chun-Bong Chow, Chi-Wai Leung & Yu-Lung Lau. (2006) Cytotoxic therapy for severe avian influenza A (H5N1) infection. The Lancet 367:9513, pages 870-873.
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AnnaCarin Horne, Chengyun Zheng, Ingrid Lorenz, Martina Lofstedt, Scott M. Montgomery, Gritta Janka, Jan-Inge Henter & E. Marion Schneider. (2005) Subtyping of natural killer cell cytotoxicity deficiencies in haemophagocytic lymphohistocytosis provides therapeutic guidance. British Journal of Haematology 129:5, pages 658-666.
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Eiichi Ishii, Shouichi Ohga, Shinsaku Imashuku, Nobuhiro Kimura, Ikuyo Ueda, Akira Morimoto, Ken Yamamoto & Masaki Yasukawa. (2005) Review of hemophagocytic lymphohistiocytosis (HLH) in children with focus on Japanese experiences. Critical Reviews in Oncology/Hematology 53:3, pages 209-223.
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Itziar Astigarraga, José Maria Prats, Aurora Navajas, Ana Fernández-Teijeiro & Alejandro Urberuaga. (2004) Near fatal cerebellar swelling in familial hemophagocytic lymphohistiocytosis. Pediatric Neurology 30:5, pages 361-364.
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H.Daniel Lacorazza, Yasushi Miyazaki, Antonio Di Cristofano, Anthony Deblasio, Cyrus Hedvat, Jin Zhang, Carlos Cordon-Cardo, Shifeng Mao, Pier Paolo Pandolfi & Stephen D. Nimer. (2002) The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer and NK-T Cells. Immunity 17:4, pages 437-449.
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I. Astigarraga Aguirre, A. Navajas Gutiérrez, A. Fernández-Teijeiro Álvarez, J. Latorre García & L. Aldamiz-Echevarria Azuara. (2002) Dificultades en el diagnóstico de la linfohistiocitosis hemofagocítica familiar. Anales de Pediatría 56:2, pages 168-170.
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